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Prevalence of malignant neoplasms in celiac disease patients-a nationwide United States population-based study

World Journal of Clinical Oncology 2024年第8期15卷 1048-1060页

作者： Maryam Bilal Haider ali al sbihi Sushmitha Nanja Reddy Peter Green Department of Gastroenterology Northshore University Health SystemEvanstonIL 60201United States Department of Hematology/Oncology University of Miami Miller School of MedicineMiamiFL 33101United States Department of Hematology/Oncology Karmanos Cancer Institute/Wayne State UniversityDetroitMI 48235United States Celiac Disease Center Columbia UniversityNew YorkNY 10032United States

BACKGROUND Celiac disease(CeD)is an autoimmune disorder triggered by the immune response to gluten in genetically predisposed *** research has unveiled a heightened risk of developing specific malignant neoplasms(MN)and various malignancies,including gastrointestinal,lymphomas,skin,and others,in individuals with *** To investigate the prevalence of MN in hospitalized CeD patients in the United *** Using data from the National Inpatient Sample spanning two decades,from January 2000 to December 2019,we identified 529842 CeD patients,of which 78128(14.75%)had *** score matching,based on age,sex,race,and calendar year,was employed to compare CeD patients with the general non-CeD population at a 1:1 *** Positive associations were observed for several malignancies,including small intestine,lymphoma,nonmelanoma skin,liver,melanoma skin,pancreas myelodysplastic syndrome,biliary,stomach,and other neuroendocrine tumors(excluding small and large intestine malignant carcinoid),leukemia,uterus,and ***,CeD patients exhibited a reduced risk of respiratory and secondary ***,certain malignancies showed null associations with CeD,including head and neck,nervous system,esophagus,colorectal,anus,breast,malignant carcinoids,bone and connective tissues,myeloma,cervix,and ovary *** Our study is unique in highlighting the detailed results of positive,negative,or null associations between different hematologic and solid malignancies and ***,it offers insights into evolving trends in CeD hospital outcomes,shedding light on advancements in its management over the past two *** findings contribute valuable information to the understanding of CeD’s impact on health and healthcare utilization.

关键词： Celiac disease Malignant neoplasm Autoimmune disorder Hospitalized patients Healthcare utilization Gastrointestinal malignancies Lymphomas Epidemiology

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Hereditary hemochromatosis:Temporal trends,sociodemographic characteristics,and independent risk factor of hepatocellular cancer–nationwide population-based study

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World Journal of Hepatology 2022年第9期14卷 1804-1816页

作者： Maryam Bilal Haider ali al sbihi Ahmed Jamal Chaudhary Syed M Haider Ahmed Iqbal Edhi Department of Internal Medicine Detroit Medical CenterWayne State UniversitySinai Grace HospitalDetroitMI 48235United States System Science Binghamton UniversityBinghamtonNY 13902United States Department of Gastroenterology William Beaumont HospitalRoyal OakMI 48073United States

BACKGROUND Hereditary hemochromatosis(HH)has an increased risk of hepatocellular cancer(HCC)both due to genetic risks and iron overload as iron overload can be carcinogenic;HH impacts the increasing risk of HCC,not only through the development of cirrhosis but concerning hepatic iron deposition,which has been studied further *** To evaluate HH yearly trends,patient demographics,symptoms,comorbidities,and hospital *** secondary aim sheds light on the risk of iron overload for developing HCC in HH patients,independent of liver cirrhosis *** study investigated HH(without cirrhosis)as an independent risk factor for *** We analyzed data from National Inpatient Sample(NIS)Database,the largest national inpatient data collection in the United States,and selected HH and HCC *** was first defined in 2011 International Classification of Disease-9th edition(ICD-9)as a separate diagnosis;the HH cohort is extracted from January 2011 to December 2019 using 275.01(ICD-9)and E83.110(ICD-10)diagnosis codes of *** were excluded from the HH cohort if they had a primary or secondary diagnostic code of cirrhosis(alcoholic,non-alcoholic,and biliary),viralhepatitis,alcoholic liver disease,non-alcoholic fatty liver disease(NAFLD),and non-alcoholic steatohepatitis(NASH).We removed these patients from the HH cohort to rule out bias or ICD-10 diagnostic *** HCC cohort is selected from January 2011 to December 2019 using the ICD-9 and ICD-10 codes of *** selected a non-HCC cohort with the 1:1 fixed ratio nearest neighbor(greedy)propensity score method using the patients'age,gender,and *** performed multivariate analysis for the risk factors of HCC in the HCC and non-HCC matched *** further analyzed HH without cirrhosis(removing HH patients with a diagnosis of cirrhosis)as an independent risk factor of HCC after adjusting all known risk factors of HCC in the multivariate *** During the 2011-2019 period,a total o

关键词： Hereditary hemochromatosis Hepatocellular carcinoma,cirrhosis Hepatitis Diabetes mellitus Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Wilson disease alpha1-antitrypsin deficiency Blood transfusion Epidemiology Demographics Big data Hospitalization

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Preparation and Characterization of alkyd Resins Based on Citrullus colocynthis Seed Oil

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Journal of Renewable Materials 2018年第6期6卷 651-661页

作者： Hassen Mohamed sbihi Hamid Shaikh Lahssen El Blidi Imed Arbi Nehdi Ubair Abdus Samad Moufida Romdhani-Younes Saud Ibrahim al-Resayes King Saud University College of ScienceChemistry DepartmentP.O.Box 2454Riyadh 1145Saudi Arabia King Saud University Chemical Engineering DepartmentP.O.Box 800Riyadh 11421Saudi Arabia Laboratory of Structural Organic Chemistry Department of ChemistryFaculty of Sciences of TunisUniversity of Tunis El Manar2092TunisTunisia

In this study,different samples of alkyd resins based on Citrullus colocynthis seed oil(CCSO)—which has a high content of linoleic acid—were prepared as a renewable raw ***(I),medium(II),and long(III)alkyd resins were synthesized using oil,glycerol,and phthalic anhydride(PA)in different *** mahaleb seed oil(PMSO),which contains conjugated linolenic acid,was blended with CCSO in different proportions to examine the effect of PMSO on the film properties of alkyd resins(IV and V).all synthesized resins were characterized by FTIR and 1H NMR spectroscopic *** resins were also cured by an epoxy resin and their film properties(pencil hardness,adhesion,gloss,and chemical resistance)were *** of these alkyds reveals that CCSO can be used as a new potential raw material for coating applications.

关键词： Citrullus colocynthis seed oil Prunus mahalab seed oil alkyd resin alcoholysis-polyesterification renewability

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GIS and Intra-Site Spatial Analyses: An Integrated Approach for Recording and Analyzing the Fossil Deposits at Casablanca Prehistoric Sites (Morocco)

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Journal of Geographic Information System 2011年第4期3卷 373-381页

作者： R. Gallotti A. Mohib M. El Graoui F. Z. sbihi-alaoui J.-P. Raynal 不详

The Mio-Plio-Pleistocene sequence at Casablanca, covering the last six million years, is well known in scientific literature. The variability and the chronology of the Acheulian sequence is documented by systematic, modern and controlled investigations in various sites (Unit L and Hominid Cave at Thomas I Quarry, Rhinoceros Cave at Oulad Hamida 1 Quarry, Sidi Abderrahman Extension Quarry, Bear’s Cave and Cap Chatelier at Sidi Abderrahman Quarry) which have taken place within the framework of the Franco-Moroccan co-operative project “Casablanca”. In order to manage the excavation data and to explore the taphonomic nature of Unit L, Hominid Cave and Rhinoceros Cave, where research is still in progress, an approach combining a Geographic Information System (GIS) and spatial analysis techniques was developed, incorporating all existing information produced from previous excavations and recent surveys of the sites. The amalgamation of this data into a GIS has resulted in a digital database that allows the production of simultaneous or separate visualizations and analyses of the fossils, artifacts and geological materials within their original spatial contexts and also permits intra-site spatial analyses that allow a comprehensive investigation of the site formation processes.

关键词： Morocco Casablanca Prehistoric Archaeology GIS Intra-Site Spatial Analyses Site Formation Processes

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经腋路臂丛神经阻滞时手臂摆放位置对阻滞起效及持续时间的影响

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麻醉与镇痛 2008年第3期4卷 29-31页

作者： Adil Ababou Nizar Marzouk Ahlam Mosadiq Ahmed sbihi 曹雷(译) 李成辉(校) The SICU and Emergency Medidne Centre Hospitalier Universitaire(CHU) de Rabat Universit6 Mohamed V Rabat Morocco 不详

背景评估经腋路臂丛神经阻滞（axinary block，AXB）后，不同手臂摆放位置对阻滞成功率、阻滞起效时间和持续时间的影响。方法实施AXB后，患者被随机分为2组：内收组患者迅速将手臂内收放置在身体两侧，外展组患者手臂依然保持阻滞时的... 详细信息

背景评估经腋路臂丛神经阻滞（axinary block，AXB）后，不同手臂摆放位置对阻滞成功率、阻滞起效时间和持续时间的影响。方法实施AXB后，患者被随机分为2组：内收组患者迅速将手臂内收放置在身体两侧，外展组患者手臂依然保持阻滞时的外展姿势。这2组患者分别保持相应姿势到阻滞成功为止。结果外展组患者感觉神经及运动神经的阻滞起效时间显著短于内收组患者，外展组患者AXB的持续时间亦显著长于内收组患者（P〈0．001）。结论实施AXB后保持手臂外展体位，可以使感觉神经和运动神经的阻滞起效更快，阻滞持续时间更长。

关键词：腋路臂丛神经阻滞持续时间摆放位置手臂阻滞起效时间运动神经感觉神经姿势

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