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Empowering Diagnosis: Cutting-Edge Segmentation and Classification in Lung Cancer Analysis

Computers, Materials & Continua 2024年第6期79卷 4963-4977页

作者： Iftikhar Naseer Tehreem Masood Sheeraz Akram Zulfiqar ali Awais Ahmad Shafiq Ur Rehman Arfan Jaffar Faculty of Computer Sciences&Information Technology The Superior UniversityLahore54000Pakistan Intelligent Data Visual Computing Research(IDVCR) Lahore54000Pakistan Information System Department College of Computer and Information SciencesImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia School of Computer Science and Electronic Engineering(CSEE) University of EssexWivenhoe ParkColchesterCO43SQUK

Lung cancer is a leading cause of global mortality *** detection of pulmonary tumors can significantly enhance the survival rate of ***,various Computer-Aided Diagnostic(CAD)methods have been developed to enhance the detection of pulmonary nodules with high ***,the existing method-ologies cannot obtain a high level of specificity and *** present study introduces a novel model for Lung Cancer Segmentation and Classification(LCSC),which incorporates two improved architectures,namely the improved U-Net architecture and the improved AlexNet *** LCSC model comprises two distinct *** first stage involves the utilization of an improved U-Net architecture to segment candidate nodules extracted from the lung ***,an improved AlexNet architecture is employed to classify lung *** the first stage,the proposed model demonstrates a dice accuracy of 0.855,a precision of 0.933,and a recall of 0.789 for the segmentation of candidate *** suggested improved AlexNet architecture attains 97.06%accuracy,a true positive rate of 96.36%,a true negative rate of 97.77%,a positive predictive value of 97.74%,and a negative predictive value of 96.41%for classifying pulmonary cancer as either benign or *** proposed LCSC model is tested and evaluated employing the publically available dataset furnished by the Lung Image Database Consortium and Image Database Resource Initiative(LIDC-IDRI).This proposed technique exhibits remarkable performance compared to the existing methods by using various evaluation parameters.

关键词： Lung cancer segmentation AlexNet U-Net classification

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Innovative approach to boosting the chemical stability of AZ31 magnesium alloy using polymer-modified hybrid metal oxides

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Journal of Magnesium and Alloys 2024年第3期12卷 1068-1081页

作者： Mosab Kaseem Ananda Repycha Safira Mohammad Aadil Tehseen Zehra Muhammad ali Khan Arash Fattah-alhosseini Corrosion and Electrochemistry Laboratory Department of Nanotechnology and Advanced Materials EngineeringSejong UniversitySeoul 05006Republic of Korea Department of Materials Engineering Bu-Ali Sina UniversityHamedan 65178-38695Iran

Meeting the demands of complex and advanced applications requires the development of high-performance hybrid materials with unique ***,the integration of polymeric frameworks with MgO/WO_(3) composite layers faces challenges due to the lack of understanding of the formation mechanism and the challenge of determining the impact of self-assembled architecture on anticorrosive *** this study,we aimed to enhance the corrosion resistance of the MgO layer produced by plasma electrolysis(PE)of AZ31 Mg alloy by incorporating WO_(3) with partially phosphorated poly(vinyl alcohol)(PPVA).Two types of porous MgO layers were produced using the PE process with an alkaline-phosphate electrolyte,one with and one without WO_(3) nanoparticles,which were subsequently immersed in an aqueous solution of *** PPVA into the WO_(3)-MgO layer resulted in hybrids being deposited in a fragmented manner,creating a“laminar reef-like structure”that sealed most of the structural defects in the *** PPVA-sealed WO_(3)-based coating exhibited superior corrosion resistance compared to the other *** analyses were employed to explore the mechanism underlying the formation of PPVA/WO_(3) hybrids on the MgO *** findings suggest that PPVA-WO_(3)-MgO hybrid coatings can potentially improve corrosion resistance in various fields.

关键词： Plasma electrolysis Poly(vinyl alcohol) Tungsten trioxide Sealing Corrosion DFT.

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PTEN as a Novel Diagnostic and Prognostic Biomarker of Head and Neck Squamous Cell Carcinoma

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Proceedings of Anticancer Research 2024年第4期8卷 75-86页

作者： Zain ali Akbar ali Nishtar Medical College Pakistan

This review article explores phosphatase and tensin homolog(PTEN)’s role in head and neck squamous cell carcinoma(HNSCC)through comprehensive expression and methylation examinations,genetic mutation investigation,and prognostic *** the UALCAN informational collection,PTEN expression examination uncovered a critical over-expression in HNSCC cells isolated from normal control samples,proposing its role in HNSCC ***,analysis of PTEN expression across various clinical limits has shown critical up-regulation in different cancer development stages,racial groups,gender,and age classes within the context of HNSCC patients,suggesting its major role in cancer *** expression was validated by utilizing the GEPIA2.0 online tool,which showed PTEN expression was particularly significantly expressed in HNSCC cancer improvement when it appeared differently from normal control ***,examining PTEN validation across different phases of cancer advancement showed dysregulation in each of the four phases with the most raised expression in stage I and the least expression in stage ***,this study investigated the promoter methylation level of PTEN,figuring out a basic relationship between HNSCC samples and normal control *** promoter methylation across various clinical limits uncovered massive variations,with specific methylation patterns seen across malignant growth stages,race groups,gender,and age *** survival and disease-free survival(OS and DFS)utilizing the KM plotter tool showed a critical relationship between PTEN expression levels in HNSCC patients,showing high PTEN expression exhibited good overall survival when showed up distinctively comparable to low PTEN expression *** addition,in disease-free survival(DFS)evaluation HNSCC patients showing low PTEN expression experienced great DFS relative to HNSCC patients with high PTEN ***,to validate PTEN expression against surviv

关键词： Head and neck squamous cell carcinoma Diagnosis Treatment Biomarker

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Chemical-assisted MMP reduction on methane-oil systems:Implications for natural gas injection to enhanced oil recovery

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Petroleum 2024年第1期10卷 101-108页

作者： Mohamed Almobarak Matthew B.Myers Colin D.Wood Yongbing Liu ali Saeedi Quan Xie Discipline of Petroleum Engineering WA School of Mines: Minerals Energy and Chemical Engineering Curtin University Commonwealth Scientific and Industrial Research Organization Curtin University Oil and Gas Innovation Centre Management State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation

Miscible natural gas injection is widely considered as a practical and efficient enhanced oil recovery technique. However, the main challenge in this process is the high minimum miscibility pressure（MMP）between natural gas and crude oil, which limits its application and recovery factor, especially in hightemperature reservoirs. Therefore, we present a novel investigation to quantify the effect of chemicalassisted MMP reduction on the oil recovery factor. Firstly, we measured the interfacial tension（IFT） of the methane-oil system in the presence of chemical or CO2to calculate the MMP reduction at a constant temperature（373K） using the vanishing interfacial tension（VIT） method. Afterwards, we performed three coreflooding experiments to quantify the effect of MMP reduction on the oil recovery factor under different injection *** interfacial tension measurements show that adding a small fraction（1.5 wt%） of the tested surfactant（SOLOTERRA ME-6） achieved 9% of MMP reduction, while adding 20 wt% of CO2to the methane yields 13% of MMP reduction. Then, the coreflooding results highlight the significance of achieving miscibility during gas injection, as the ultimate recovery factor increased from 65.5% under immiscible conditions to 77.2% using chemical-assisted methane, and to 79% using gas mixture after achieving near miscible condition. The results demonstrate the promising potential of the MMP reduction to significantly increase the oil recovery factor during gas injection. Furthermore, these results will likely expand the application envelop of the miscible gas injection, in addition to the environmental benefits of utilizing the produced gas by re-injection/recycling instead of flaring which contributes to reducing the greenhouse gas emissions.

关键词： Gas injection Enhanced oil recovery Miscibility Coreflooding

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Estimation of monthly global solar radiation over twelve major cities of Libya

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Energy and Built Environment 2024年第1期5卷 46-57页

作者： Alhassan ali Teyabeen Najeya B.Elhatmi Akram A.Essnid F.Mohamed Libyan Center for Solar Energy Research and Studies TripoliLibya Libyan Authority of Scientific Research TripoliLibya

This study aims to estimate monthly averaged daily horizontal global solar *** climatological data collected at twelve major cities located across Libya’s map were used to establish 7 different empirical *** empirical coefficients of the models were calculated using the least square *** accuracy of the models was evaluated using different statistical criteria such as Taylor diagram,mean absolute percentage error,MAPE,and root mean square error,*** results indicated that the sunshine duration-based models are more accurate than air temperature-based models,and the best performance was obtained by the quadratic regression model for all twelve Libyan ***,this regression model can be used for the prediction of monthly mean horizontal global solar radiation at a specific site across Libya’s regions with minimum ***,the results of the global solar irradiance produced by this method can be used for designing solar systems applications.

关键词： Monthly global solar radiation Clearness index Empirical models Performance evaluation Taylor diagram Libya

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Surface Morphology and Thermo-Electrical Energy Analysis of Polyaniline (PANI) Incorporated Cotton Fabric

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Energy Engineering 2024年第1期121卷 1-12页

作者： Md.Shohan Parvez Md.Mustafizur Rahman Mahendran Samykano Mohammad Yeakub ali Automotive Engineering Research Group Faculty of Mechanical and Automotive Engineering TechnologyUniversiti Malaysia Pahang Al-Sultan AbdullahPekanMalaysia Department of Textile Engineering Khulna University of Engineering&Technology(KUET)KhulnaBangladesh Centre for Research in Advanced Fluid and Processes(CARIFF) Universiti Malaysia Pahang Al-Sultan AbdullahLebuhraya Tun RazakGambangMalaysia Mechanical Engineering Programme Area Faculty of EngineeringUniversiti Teknologi BruneiBruneiDarussalam

With the exponential development in wearable electronics,a significant paradigm shift is observed from rigid electronics to flexible wearable ***(PANI)is considered as a dominant material in this sector,as it is endowed with the optical properties of both metal and ***,its widespread application got delineated because of its irregular rigid form,level of conductivity,and precise choice of *** PANI in textile materials can generate promising functionality for wearable *** research work employed a straightforward in-situ chemical oxidative polymerization to synthesize PANI on Cotton fabric surfaces with varying dopant(HCl)***-treatment using NaOH is implemented to improve the conductivity of the fabric surface by increasing the monomer *** research explores the morphological and structural analysis employing SEM,FTIR and *** surface resistivity was measured using a digital multimeter,and thermal stability is measured using *** successful polymerization,a homogenous coating layer is *** is revealed that the simple pre-treatment technique significantly reduces the surface resistivity of Cotton fabric to 1.27 kΩ/cm with increasing acid concentration and thermal *** electro-thermal energy can also reach up to 38.2°C within 50 s with a deployed voltage of 15 *** modified fabric is anticipated to be used in thermal regulation,supercapacitor,sensor,UV shielding,antimicrobial and other prospective functional applications.

关键词： Polyaniline cotton in-situ polymerization SEM TGA heating fabric

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Numerical study of convective heat transfer in static arrangements of particles with arbitrary shapes:A monolithic hybrid lattice Boltzmann-finite difference-phase field solver

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Particuology 2024年第2期85卷 186-197页

作者： Reza Namdar Mohammadhassan Khodsiani Hesameddin Safari Tanya Neeraj Seyed ali Hosseini Frank Beyrau Benoit Fond Dominique Thevenin Fathollah Varnik Interdisciplinary Centre for Advanced Materials Simulation(ICAMS) Ruhr-University BochumBochum44801Germany Laboratory of Technical Thermodynamics University of Magdeburg"Otto von Guericke"Magdeburg39106Germany Laboratory of Fluid Dynamics and Technical Flows University of Magdeburg"Otto von Guericke"MagdeburgD-39106Germany Department of Mechanical and Process Engineering ETH ZurichZurich8092Switzerland ONERA The French Aerospace Lab Department of AerodynamicsAeroelasticity and Acoustics(DAAA)Paris-Saclay UniversityMeudon92190France

A compressible lattice Boltzmann-finite difference method is extended by the phase-field approach into a monolithic scheme to study fluid flow and heat transfer through regular arrangements of solid bodies of circular,elliptical and irregular *** advantage of using the phase-field method is demon-strated both in its simplicity of accounting for flow and thermal boundary conditions at solid surfaces with irregular shapes and in the capability of generating such complex-shaped *** an array of discs,numerical results for the overall solid-to-gas heat transfer rate are validated via experiments on flow through arrays of hot *** thus validated compressible LB-FD-PF hybrid scheme is used to study the dependence of heat transfer on flow and thermal boundary conditions(Reynolds number,temperature difference between the hot solid bodies and the inlet gas),porosity as well as on the shape of solid *** are rationalized in terms of the residence time of the gas close to the solid body and downstream variations of gas velocity and *** for further applications of the proposed methodology are also discussed.

关键词： Lattice Boltzmann method Finite difference scheme Convective heat transfer Diffuse interface Thermal compressible flow

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Combinational therapy with Myc decoy oligodeoxynucleotides encapsulated in nanocarrier and X-irradiation on breast cancer cells

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Oncology Research 2024年第2期32卷 309-323页

作者： BEHROOZ JOHARI MILAD PARVINZAD LEILAN MAHMOUD GHARBAVI YOUSEF MORTAZAVI ali SHARAFI HAMED REZAEEJAM Department of Medical Biotechnology School of MedicineZanjan University of Medical SciencesZanjanIran Zanjan Pharmaceutical Biotechnology Research Center Zanjan University of Medical SciencesZanjanIran Nanotechnology Research Center Ahvaz Jundishapur University of Medical SciencesAhvazIran Department of Radiology Technology School of Allied Medical SciencesZanjan University of Medical SciencesZanjanIran

The Myc gene is the essential oncogene in triple-negative breast cancer(TNBC).This study investigates the synergistic effects of combining Myc decoy oligodeoxynucleotides-encapsulated niosomes-selenium hybrid nanocarriers with X-irradiation exposure on the MDA-MB-468 cell *** and scramble ODNs for Myc transcription factor were designed and synthesized based on promoter sequences of the Bcl2 *** nanocarriers were synthesized by loading Myc ODNs and selenium into chitosan(Chi-Se-DEC),which was then encapsulated in niosome-nanocarriers(NISM@Chi-Se-DEC).FT-IR,DLS,FESEM,and hemolysis tests were applied to confirm its characterization and physicochemical ***,cellular uptake,cellular toxicity,apoptosis,cell cycle,and scratch repair assays were performed to evaluate its anticancer effects on cancer *** anticancer assessments were repeated under X-ray irradiation conditions(fractionated 2Gy).Physicochemical characteristics of niosomes containing SeNPs and ODNs showed that it is synthesized *** revealed that the anticancer effect of NISM@Chi-Se-DEC can be significantly improved in combination with X-ray irradiation *** can be concluded that NISM@Chi-Se-DEC nanocarriers have the potential as a therapeutic agent for cancer treatment,particularly in combination with radiation therapy and in-vivo experiments are necessary to confirm the efficacy of this nano-drug.

关键词： Combinational therapy Antisense therapy Myc signaling pathway Niosomes Radiation therapy SeNPs

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Comparative Study of the Effects of Nano ZnO and CuO on the Biodegradation,Biocompatibility,and Antibacterial Properties of Micro-arc Oxidation Coating of Magnesium Alloy

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Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 242-254页

作者： Ying Shen Xianfeng Shan Iniobong P.Etim Muhammad ali Siddiqui Yang Yang Zewen Shi Xuping Su Junxiu Chen Key Laboratory of Materials Surface Science and Technology of Jiangsu Province Changzhou UniversityChangzhou213164China Department of Stomatology The Affiliated Xinhua Hospital of Dalian UniversityDalian116000China Department of Physics University of CalabarCalabar540242Nigeria Metallurgical Engineering Department NED University of Engineering and TechnologyUniversity RoadKarachi75270Pakistan Ningbo No.2 Hospital Ningbo315010China

This research systematically examined the degradation,antibacterial effects,and biocompatibility of micro-arc oxidation(MAO)coatings with nano CuO and ZnO on extruded Mg *** copper(Cu)and Zinc(Zn)possess antibacterial *** findings demonstrated that adding ZnO will appreciably reduce the degradation rate of MAO-coating alloy due to the self-sealing micro ***+MAO coating exhibited excellent antibacterial performance,with an antibacterial rate of over 90%within 6 h co-cultured with Staphylococcus ***,the antibacterial rate of ZnO+MAO coating reached 90%after 12 h *** test using MG63 cell indicated that the incorporation of CuO and ZnO did not notably affect the cell viability rate of the ***,after 14 days of culture,the CuO+MAO and ZnO+MAO coated samples exhibited higher alkaline phosphatase(ALP)activity than the MAO-coated and uncoated samples,suggesting favorable osteogenic properties.

关键词： Copper oxide Zinc oxide Micro-arc oxidation(MAO)coating Corrosion behavior Antibacterial characteristics

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A Comprehensive Review on Charging Topologies and Power Electronic Converter Solutions for Electric Vehicles

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 675-694页

作者： Abdelfatah ali Hossam H.H.Mousa Mostafa F.Shaaban Maher A.Azzouz Ahmed S.A.Awad the Department of Electrical Engineering American University of Sharjah26666 SharjahUnited Arab Emirates the Department of Electrical Engineering South Valley University83523 QenaEgypt the Department of Electrical and Computer Engineering University of WindsorWindsorON N9B 3P4 Canada Electrical Engineering Department Qatar UniversityDoha 2713Qatar Department of Electrical and Computer Engineering Sultan Qaboos UniversityMuscat123Oman

Electric vehicles(EVs)are becoming more popular worldwide due to environmental concerns,fuel security,and price *** performance of EVs relies on the energy stored in their batteries,which can be charged using either AC(slow)or DC(fast)***,EVs can also be used as mobile power storage devices using vehicle-to-grid(V2G)*** electronic converters(PECs)have a constructive role in EV applications,both in charging EVs and in ***,this paper comprehensively investigates the state of the art of EV charging topologies and PEC solutions for EV *** examines PECs from the point of view of their classifications,configurations,control approaches,and future research prospects and their impacts on power *** can be classified into various topologies:DC-DC converters,AC-DC converters,DC-AC converters,and AC-AC *** address the limitations of traditional DC-DC converters such as switching losses,size,and high-electromagnetic interference(EMI),resonant converters and multiport converters are being used in high-voltage EV ***,power-train converters have been modified for high-efficiency and reliability in EV *** paper offers an overview of charging topologies,PECs,challenges with solutions,and future trends in the field of the EV charging station applications.

关键词： Charging station charging topology electric vehicle power electronic converter vehicle-to-grid

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