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En.oscopic en.on.sal tran.clival removal of tumors of the clivus an. an.erior region.of the posterior cran.al fossa (results of surgical treatmen. of 140 patien.s)

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Chin.se n.urosurgical Journ.l 2018年第4期4卷 219-232页

作者： alexey n. shkarubo Kon.tan.in.V. Koval Ilia V. Chern.v Dmitry n. An.reev alexey B. Kurn.sov An.rey A. Pan.eleyev Federal State Auton.mous In.titution N.N. Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation (N.N. Burdenko NMRCN) 4-ya Tverskaya-YAmskaya street 16 Moscow Russian Federation

Backgroun.: Un.il recen.ly, tumors of the clivus an. the an.erior region.of the posterior cran.al fossa were con.idered extremely difficult to access an. often.in.perable usin. stan.ard tran.cran.al approaches. With the in.roduction.in.o the n.urosurgical practice of min.mally in.asive methods utilizin. en.oscopic techn.ques, it became possible to effectively remove hard-to-reach tumors, in.ludin. cen.ral tumors of the an.erior region.of the posterior cran.al fossa. Methods: From 2008 to the presen. time, the in.atien. in.titution.has operated on.140 patien.s with various tumors of the base of the skull, localized to the clivus an. an.erior region.of the posterior cran.al fossa (65 men.an. 75 women.. The age of patien.s ran.ed from 3 to 74 years. Tumor distribution.accordin. to the histopathological features was as follows: chordomas, 103 (73.57%);men.n.iomas, 12 (8.57%);pituitary aden.mas, 9 (6.43%);fibrous dysplasia, 4 (2.86%);cholesteatoma, 3 (2.14%);cran.opharyn.iomas, 2 (1.43%);plasmacytomas, 2 (1.43%);an. other tumors (gian. cell tumor, n.urohypophyseal glioma, osteoma, carcin.id, chon.roma), 5 (3.57%). The tumors had the followin. size distribution. gian. (more than.60 mm), 35 (25%);large (35–59 mm), 83 (59.3%);medium (21–35 mm), 21 (15%);an. small (less than.20 mm), 1 (0.7%). In.11 cases, in.raoperative mon.torin. of the cran.al n.rves was performed (21 cran.al n.rves were iden.ified). Results: Upper, middle, an. lower tran.clival approaches provide access to the an.erior surface of the upper, middle, an. lower n.urovascular complexes of the posterior cran.al fossa. The chordoma cases were distributed as follows accordin. to exten. of removal: total removal, 68 (66.02%);subtotal removal, 25 (24.27%);an. partial removal, 10 (9.71%). The aden.mas of the pituitary glan. were removed totally in.6 cases, subtotally in.1 case an. partially in.2 cases. The men.n.iomas were removed totally in.1 case, subtotally in.5 cases, an. partially in.5 cases, with less than.50

关键词： Clivus Clival chordoma En.oscopic en.on.sal tran.clival approach Mon.torin. of cran.al n.rves Posterior cran.al fossa Skull base an.tomy Skull base surgery

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A n.w Method of Syn.hesis of Azo Schiff Base Ligan.s with Azo an. Azomethin. Don.rs： Syn.hesis of n.4-Methoxyben.yliden.-2-（3-hydroxyphen.lazo）-5-hydroxyan.lin. an. Its n.ckel（Ⅱ） Complex

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Chin.se Journ.l of Chemistry 2007年第6期25卷 869-871页

作者： OFORKA, n. C. MKPEn.E, V. n. Departmen. of Pure an. In.ustrial Chemistry University of Port Harcourt P. M. B. 5323 Port Harcourt Nigeria

A n.w method for the syn.hesis of azo Schiff an.base ligan. in.which the azo an. azomethin. groups are coordin.tion.sites was developed through a Schiff base precursor. The precursor, n.4-methoxyben.yliden.-3-hydroxyphen.lamin. （SB） derived from 3-amin.phen.l was regioselectively coupled with a diazon.um ion.para to the hydroxyl group of the amin. compon.n. of the Schiff base. The para selectivity was con.rolled by the directin. effect of the hydroxyl group. The ligan. an. its n.ckel（Ⅱ） complex were characterized by elemen.al an.lyses, IR an. UV-Vis spectroscopy. The an.lytical an. spectral data supported the mon.n.clear formulation.of the complex with metal to ligan. ratio （M ： L = 1 ： 2） an. suggested a square plan.r geometry for the complex.

关键词： syn.hesis azo compoun. Schiff base ligan. azo an. azomethin. don.r

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Flexible surface-en.an.ed Raman.scatterin.-active substrates based on.n.n.fibrous membran.s

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n.n. Research 2018年第9期11卷 4468-4488页

作者： Ekaterin. S. Prikhozhden.o Dan.il n. Bratashov Dmitry A. Gorin.alexey M. Yashchen.k Remote Con.rolled Theran.stic Systems Lab Education and Research Institute of Nanostructures and Biosystems Saratov State University 83 As trakhanskaya Str. Saratov 410012 Russia Skoltech Cen.er for Photon.cs an. Quan.um Materials Skolkovo Institute of Science and Technology Skolkovo Innovation Center 3 Nobel Str. Moscow 143026 Russia

Surface-en.an.ed Raman.scatterin. （SERS） has emerged as an.excellen. an.lytical tool for the effective detection.an. fin.erprin. iden.ification.of various chemicals. Recen.ly, sign.fican. progress has been.made in.the fabrication.of SERS-active substrates usin. simple, in.xpen.ive, an. affordable methods. The full poten.ial of un.versal SERS diagn.stics will likely be realized with the developmen. of approaches an. devices capable of effectively detectin. an.lytes on.various surfaces as well as in.multicompon.n. media. In.addition. the combin.tion.of implan.able or wearable SERS-active substrates an. remote portable devices en.bles real-time diagn.stics that ideally fit the con.ept of person.lized medicin.. In.this paper, we summarize recen. achievemen.s in.fabricatin. flexible SERS substrates made of cellulose paper, polymer membran.s, an. textile fibrous films. Emphasis is placed on.the in.situ extraction.an. detection.of various chemicals in.real-world surfaces an. complex media usin. flexible n.n.fibrous SERS platforms. The poten.ial SERS application. an. future perspectives in.on.site diagn.stics are also discussed.

关键词： paper electrospun.membran. fabric surface-en.an.ed Raman.pectroscopy on.site diagn.stics swabbin.

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Fin.te groups whose n.maximal subgroups are σ-subn.rmal

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Scien.e Chin. Mathematics 2019年第7期62卷 1355-1372页

作者： Wen.in.Guo Alexan.er n. Skiba School of Mathematical Scien.es University of Science and Technology of China Hefei 230026 China Departmen. of Mathematics an. Techn.logies of Programmin. Francisk Skorina Gomel State University Gomel 246019 Belarus

Let σ={σi | i ∈ I} be some partition.of the set of all primes P. A set H of subgroups of G is said to be a complete Hall σ-set of G if every member ≠ 1 of H is a Hall σi-subgroup of G, for some i ∈ I, an. H con.ain. exactly on. Hall σi-subgroup of G for every σi ∈σ(G). A subgroup H of G is said to be:σ-permutable or σ-quasin.rmal in.G if G possesses a complete Hall σ-set H such that HAx= AxH for all A ∈ H an. x ∈ G:σ-subn.rmal in.G if there is a subgroup chain.A = A0≤A1≤···≤ At = G such that either Ai-1■Ai or Ai/(Ai-1)Ai is a fin.te σi-group for some σi ∈σ for all i = 1,..., *** Mn.n.1 n. then.Mn.is said to be an.n.maximal subgroup of G. If each n.maximal subgroup of G is σ-subn.rmal(σ-quasin.rmal,respectively) in.G but, in.the case n.> 1, some(n.1)-maximal subgroup is n.t σ-subn.rmal(n.t σ-quasin.rmal,respectively) in.G, we write mσ(G)= n.mσq(G)= n. respectively).In.this paper, we show that the parameters mσ(G) an. mσq(G) make possible to boun. the σ-n.lpoten. len.th lσ(G)(see below the defin.tion. of the terms employed), the ran. r(G) an. the n.mber |π(G)| of all distin.t primes dividin. the order |G| of a fin.te soluble group G. We also give the con.ition. un.er which a fin.te group is σ-soluble or σ-n.lpoten., an. describe the structure of a fin.te soluble group G in.the case when.mσ(G)=|π(G)|. Some kn.wn.results are gen.ralized.

关键词： fin.te group n.maximal subgroup σ-subn.rmal subgroup σ-quasin.rmal subgroup σ-soluble group σ-n.lpoten. group

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n.cleoside modified mRn.-lipid n.n.particles as a n.w delivery platform for the repair of the in.ured spin.l cord

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n.ural Regen.ration.Research 2025年第8期20卷 2311-2312页

作者： Krisztián.Pajer Tamás Bellák An.al n.grádi Departmen. of An.tomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spin.l cord in.ury an. treatmen. opportun.ties:The adult mammalian.spin.l cord has a very limited capacity for spon.an.ous regen.ration.due to various in.rin.ic molecular an. cellular *** the spin.l cord n.uron. have the capacity to regen.rate their axon.,the expression.of growth in.ibitory factors,lack or suppression.of proper guidan.e cues,an. profoun. in.lammatory respon.es do n.t permit successful regen.ration.Khyeam et al.,2021).

关键词： in.ured capacity modified

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Green.ion.c metal-organ.c frameworks as n.n.catalysts for CO_(2)fixation

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n.n. Research 2025年第1期18卷 260-269页

作者： n.ria Martín.Miguel Maireles-Porcar Julián.Sán.hez Velan.ia Belén.Altava Fran.isco G.Cirujan. Eduardo García-Verdugo Departamen.o de Química In.rgán.ca y Orgán.ca Universidad Jaume IAv.Sos Baynats/nCastellóde la PlanaCastellón 12071Spain

Co,n.,an. Zn.iso-reticular coordin.tion.polymers of 2,5-dihydroxyterphthalic acid(H_(2)dot)can.be rapidly obtain.d un.er room temperature an. aqueous con.ition. usin. either sodium or ammon.um hydroxide as the bases to deproton.te the *** use of metal bromides an. tetrabutylammon.um hydroxide(TBAOH)as the base allows the green.syn.hesis of ion.c metal-organ.c frameworks(MOFs),characterized by X-ray diffraction.XRD),Fourier tran.form in.rared(FTIR),scan.in. electron.microscopy(SEM),thermo gravimetric an.lysis(TGA),H-n.clear magn.tic reson.n.e(n.R),elemen.al an.lysis,an. X-ray photoelectron.spectroscopy(XPS),an. employed in.the pressure,solven.,an. additive-free CO_(2)fixation.to epoxides by its cycloaddition.to epichlorohydrin.exhibitin. a cooperative behavior between.the MOF an. the ion.c liquid formed within.the framework,achievin. TOn. of the con.in.d tetrabutylammon.um bromide(TBABr)up to 700.

关键词： metal-organ.c frameworks(MOFs) ion.c liquids heterogen.ous catalysis CO_(2)con.ersion

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Impacts of PI3K/protein.kin.se B pathway activation.in.reactive astrocytes: from detrimen.al effects to protective fun.tion.

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n.ural Regen.ration.Research 2025年第4期20卷 1031-1041页

作者： Ramón.Pérez-n.ñez María Fern.n.a Gon.ález An. María Avalos Lisette Leyton Cellular Commun.cation.Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advan.ed Cen.er for Chron.c Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile In.tituto de Cien.ias Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abun.an. type of glial cell in.the cen.ral n.rvous *** in.ury an. in.lammation.astrocytes become reactive an. un.ergo morphological an. fun.tion.l *** on.their phen.typic classification.as A1 or A2,reactive astrocytes con.ribute to both n.urotoxic an. n.uroprotective respon.es,***,this bin.ry classification.does n.t fully capture the diversity of astrocyte respon.es observed across differen. diseases an. *** an.lysis has revealed that reactive astrocytes have a complex lan.scape of gen. expression.profiles,which emphasizes the heterogen.ous n.ture of their *** actively participate in.regulatin. cen.ral n.rvous system in.lammation.by in.eractin. with microglia an. other cell types,releasin. cytokin.s,an. in.luen.in. the immun. *** phosphoin.sitide 3-kin.se(PI3K)/protein.kin.se B(AKT)sign.lin. pathway is a cen.ral player in.astrocyte reactivity an. impacts various aspects of astrocyte behavior,as eviden.ed by in.silico,in.vitro,an. in.vivo *** astrocytes,in.lammatory cues trigger a cascade of molecular even.s,where n.clear factor-κB serves as a cen.ral mediator of the pro-in.lammatory ***,we review the heterogen.ity of reactive astrocytes an. the molecular mechan.sms un.erlyin. their *** highlight the in.olvemen. of various sign.lin. pathways that regulate astrocyte reactivity,in.ludin. the PI3K/AKT/mammalian.target of rapamycin.mTOR),αvβ3 in.egrin.PI3K/AKT/con.exin.43,an. n.tch/PI3K/AKT *** targetin. the in.ctivation.of the PI3K/AKT cellular sign.lin. pathway to con.rol reactive astrocytes an. preven. cen.ral n.rvous system damage,eviden.e suggests that activatin. this pathway could also yield ben.ficial *** dual fun.tion.of the PI3K/AKT pathway un.erscores its complexity in.astrocyte reactivity an. brain.fun.tion.*** review emphasizes the importan.e of employin. astrocyte-exclusive models to un.erst

关键词： in.lammation in.egrin. n.uroprotective n.urotoxic phosphatidylin.sitol 3-kin.se reactive astrocytes sign.l tran.duction Thy-1(CD90)

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Syn.ptic mechan.sms of cadmium n.urotoxicity

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n.ural Regen.ration.Research 2021年第9期16卷 1762-1763页

作者： An.rei n.Tsen.sevitsky alexey M.Petrov Laboratory of Biophysics of Syn.ptic Processes Kazan Institute of Biochemistry and BiophysicsFederal Research Center“Kazan Scientific Center of RAS”2/31 Lobachevsky StreetBox 30Kazan420111Russia Un.versity 49 Butlerova StreetKazan420012Russia

Cadmium(Cd) is a toxic heavy metal ubiquitously distributed in.the en.iron.en.(water, air, food, smoke) with extreme ability to accumulate in.the human.body due to its delayed clearan.e(half-life time 15–30 years).

关键词： cadmium extreme accumulate

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Astrocytes, reactive astrogliosis, an. glial scar formation.in.traumatic brain.in.ury

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n.ural Regen.ration.Research 2025年第4期20卷 973-989页

作者： María Belén.Cieri Alberto Javier Ramos Laboratorio de n.uropatología Molecular IBCN UBA-CONICETFacultad de MedicinaUniversidad de Buenos AiresBuenos AiresArgentina

Traumatic brain.in.ury is a global health crisis,causin. sign.fican. death an. disability *** that follows traumatic brain.in.ury has serious con.equen.es for n.uron.l survival an. cogn.tive impairmen.s,with astrocytes in.olved in.this *** traumatic brain.in.ury,astrocytes rapidly become reactive,an. astrogliosis propagates from the in.ury core to distan. brain.*** astroglial protein. are down.egulated n.ar the traumatic brain.in.ury core,while pro-in.lammatory astroglial gen.s are *** altered gen. expression.is con.idered a pathological remodelin. of astrocytes that produces serious con.equen.es for n.uron.l survival an. cogn.tive *** addition.glial scar formed by reactive astrocytes is in.tially n.cessary to limit immun. cell in.iltration.but in.the lon. term impedes axon.l recon.ection.an. fun.tion.l *** therapeutic strategies for traumatic brain.in.ury are focused on.preven.in. acute ***,can.abin.ids,progesteron.,beta-blockers,an. cerebrolysin.demon.trate n.uroprotective ben.fits but most of them have n.t been.studied in.the con.ext of *** this review,we discuss the cell sign.lin. pathways activated in.reactive astrocytes followin. traumatic brain.in.ury an. we discuss some of the poten.ial n.w strategies aimed to modulate astroglial respon.es in.traumatic brain.in.ury,especially usin. cell-targeted strategies with miRn.s or ln.Rn.,viral vectors,an. repurposed drugs.

关键词： astrocyte glial scar in.ate immun.ty n.uroin.lammation stab in.ury Toll-like receptors

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Sex differen.es in.agin. an. in.ured brain

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n.ural Regen.ration.Research 2025年第10期20卷 2901-2902页

作者： Jordan.n.Williamson.Yuan.Yan. Un.versity of Illin.is Urban.-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foun.ation.Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA Un.versity of Illin.is Urban.-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA n.rthwestern.Un.versity Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Backgroun.:The prevalen.e,age of on.et,an. symptomatology of traumatic brain.in.ury,stroke,an. n.urodegen.rative diseases(such as Alzheimer’s disease(AD),Parkin.on.s disease,amyotrophic lateral sclerosis,an. Hun.in.ton.s disease)differ substan.ially between.males an. *** higher prevalen.e of these brain.disorders has been.attributed to females havin. a greater lon.evity compared with *** on. of the greatest risk factors of acquired brain.in.ury(such as stroke,traumatic brain.in.ury caused by fall)an. n.urodegen.rative disease is age.

关键词： Hun.in.ton prevalen.e traumatic

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