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A single session of strength training changed plasma levels of resistin,but not leptin in overweight and obese men

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Sports Medicine and Health Science 2024年第4期6卷 324-330页

作者： Yago Martins Fortes Antonio Felipe Souza-Gomes alessandro Roberto Silveira Moreira Leo Nogueira Campos Samara Silva de Moura Lucelia Scarabeli Silva Barroso Marcelo Henrique Salviano de Faria Heliana de Barros Fernandes Aline Silva de Miranda Hugo Cesar Martins-Costa Ana Cristina Simoes e Silva Janaina Matos Moreira Albena Nunes-Silva Laboratory of Inflammation and Exercise Immunology Department of Physical EducationSchool of Physical EducationFederal University of Ouro PretoOuro PretoMGBrazil Postgraduate Program in Health and Nutrition Nutrition SchoolFederal University of Ouro PretoOuro PretoMGBrazil Interdisciplinary Medical Research Laboratory Faculty of MedicineFederal University of Minas GeraisBelo HorizonteMGBrazil Neurobiology Laboratory Institute of Biological SciencesFederal University of Minas GeraisBelo HorizonteMGBrazil Department of Physical Education Pontifical Catholic University of Minas GeraisBrazil Department of Pediatrics Faculty of MedicineFederal University of Minas Gerais(UFMG)Belo HorizonteMGBrazil

Obesity has a complex multifactorial etiology and is characterized by excessive accumulation of adipose *** adipose tissue has deleterious effects on health because it secretes large amounts of inflammatory *** calorie restriction associated with strength training may be useful in managing chronic systemic *** study aimed to evaluate the acute effect of a single strength-training session on plasma adipokine levels in sedentary,overweight,and obese young *** study included twelve men(Age:[34.95±9.77]years;Height:[174.16±3.66]centimeter[cm];Weight:[97.83±12.87]kilogram(kg);body mass index[BMI]:[32.30±4.51]kg/m2),who performed a single strength training *** strength training protocol consisted of 4 sets of 12 repetitions in the following six exercises,45°leg press,bench press,leg extension,machine row,leg curl,and shoulder *** samples were collected before,immediately after,and 1-h subsequent after strength *** plasma levels of resistin and leptin were measured.A significant decrease in resistin levels were found 1 h after the strength training session if compared to levels before the training session(pre-[before][2390±1199]picograms per milliliter[pg/mL]vs post-1 h[1-h subsequent][1523±798],6 pg/mL,p=0.0028).The plasma leptin levels did not differ at any time *** conclusion,a very well controlled single session of strength training significantly decreased the plasma levels of resistin without altering the concentration of leptin in overweight and obese *** effect,at least in part,supports the benefits of exercise by reducing the low grade inflammation and insulin resistance in obesity.

关键词： Strength training Adipose tissue Obesity Chronicinflammation Resistin Leptin

Matrix Algebras in Non-Hermitian Quantum Mechanics

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Communications in Theoretical Physics 2011年第7期56卷 96-98页

作者： alessandro Sergi School of Physics University of KwaZulu-NatalPietermaritzburg CampusPrivate Bag X01 Scottsville

In principle, non-Hermitian quantum equations of motion can be formulated using as a starting point either the Heisenberg＇s or the Schroedinger＇s picture of quantum dynamics. Here it is shown in both cases how to map the algebra of commutators, defining the time evolution in terms of a non-Hermitian Hamiltonian, onto a non-Hamiltonian algebra with a Hermitian Hamiltonian. The logic behind such a derivation is reversible, so that any Hermitian Hamiltonian can be used in the formulation of non-Hermitian dynamics through a suitable algebra of generalized （non-Hamiltonian） commutators. These results provide a general structure （a template） for non-Hermitian equations of motion to be used in the computer simulation of open quantum systems dynamics.

关键词： non-hermitian quantum mechanics non-Hamiltonian dynamics open quantum systems

Recent Advances in the Catalytic Functionalization of “Electrophilic” Indoles

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Chinese Journal of Chemistry 2020年第3期38卷 287-294页

作者： alessandro Cerveri Marco Bandini Dipartimento di Chimica"Giacomo Ciamician"-Alma Moter Studiorum Universita di Bologna Via Selmi 240126 BolognaItaly Consorzio C.I.N.M.P.I.S.Via Selmi 2 40126 BolognaItaly

When "dark"is bright:the scarcely explored electrophilic profile of the indolyl core(dark side)continues to inspire developments in organic synthesis by means of new catalytic *** advancements in the field enabled mol... 详细信息

关键词： chemistry. Catalytic heterocyclic

Cysteine carboxyethylation:a novel post-translational modification associated with autoimmune arthritis

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3561-3562页

作者： alessandro Didonna Department of Anatomy and Cell Biology Brody School of MedicineEast Carolina UniversityGreenvilleNC 27834USA

In a study recently published in Science,Zhai et *** that protein carboxyethylation results in the formation of neoantigens with the ability to trigger autoimmune arthritis in the context of ankylosing spondylitis(AS)pathology.1 This work defines a novel molecular mechanism underlying immune tolerance breakdown,which could serve as a target for innovative therapeutic strategies against AS and other autoimmune disorders.

关键词： autoimmune pathology

The association of type and number of high-risk criteria with cancer-specific mortality in prostate cancer patients treated with radical prostatectomy

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Current Urology 2024年第2期18卷 128-132页

作者： Francesco Chierigo Rocco Simone Flammia GabrieleSorce Benedikt Hoeh Lukas Hohenhorst Andrea Panunzio Zhe Tian Fred Saad Marcus Graefen Michele Gallucci Alberto Briganti Francesco Montorsi Felix K.H.Chun Shahrokh F.Shariat alessandro Antonelli Giovanni Guano Guglielmo Mantica Marco Borghesi Nazareno Suardi Carlo Terrone Pierre I.Karakiewicz Department of Surgical and Diagnostic Integrated Sciences University of GenovaGenovaItaly IRCCS Ospedale Policlinico San Martino GenovaItaly Cancer Prognostics and Health Outcomes Unit Division of UrologyUniversity ofMontréal Health CenterMontréalQuébecCanada Department of Urology IRCCS Policlinico San MartinoGenovaItaly Department of Maternal-Child and Urological Sciences Sapienza Rome UniversityPoliclinico Umberto I HospitalRomeItaly Department of Urology University Hospital FrankfurtFrankfurt am MainGermany Martini-Klinik Prostate Cancer Center University Hospital Hamburg-EppendorfHamburgGermany Department of Urology University of VeronaAzienda Ospedaliera Universitaria Integrata di VeronaVeronaItaly Division of Experimental Oncology/Unit of Urology URIUrological Research InstituteIRCCS San Raffaele Scientific InstituteMilanItaly Department of Urology Comprehensive Cancer CenterMedical University of ViennaViennaAustria Department of Urology Weill Cornell Medical CollegeNew YorkNYUSA Department of Urology University of Texas SouthwesternDallasTXUSA Department of Urology Second Faculty of MedicineCharles UniversityPragueCzech Republic Institute for Urology and Reproductive Health I.M.Sechenov First Moscow State Medical UniversityMoscowRussia Division of Urology Department of Special SurgeryJordan University HospitalThe University of JordanAmmanJordan

Objectives:This study aimed to test the association between of type and number of D'Amico high-risk criteria(DHRCs)with cancer-specific mortality(CSM)in high-risk prostate cancer patients treated with radical *** and methods:In the Surveillance,Epidemiology,and End Results database(2004–2016),we identified 31,281 radical prostatectomy patients with at least 1 DHRC,namely,prostate-specific antigen(PSA)>20 ng/mL(hrPSA),biopsy Gleason Grade Group(hrGGG)score of 4 and 5,or clinical tumor stage≥T3(hrcT).Multivariable Cox regression models and competing risks regression models(adjusting for other cause mortality)tested the association between DHRCs and 5-year ***:Of 31,281 patients,14,394(67%)exclusively harbored hrGGG,3189(15%)harbored hrPSA,and 1781(8.2%)harbored *** 2132 patients(6.8%)harbored a combination of the 2 DHRCs,and 138(0.6%)had all 3 ***-year CSMrates ranged from 0.9%to 3.0%when any individual DHRC was present(hrcT,hrPSA,and hrGGG,in that order),1.6%to 5.9%when 2 DHRCs were present(hrPSA-hrcT,hrcT-hrGGG,and hrPSA-hrGGG,in that order),and 8.1%when all 3 DHRCs were *** regression models and competing risks regression confirmed the independent predictor status of DHRCs for 5-year CSM that was observed in univariable analyses,with hazard ratios from 1.00 to 2.83 for 1 DHRC,2.35 to 5.88 for combinations of 2 DHRCs,and 7.13 for all 3 ***:Within individual DHRCs,hrcT and hrPSA exhibited weaker effects than hrGGG ***,a dose-response effect was identified according to the number of ***,the type and number of DHRCs allow further risk stratification within the high-risk subgroup.

关键词： High risk prostate cancer Radical prostatectomy Cancer-specific mortality Staging SEER

Comparing leaf area index estimates in a Mediterranean forest using field measurements, Landsat 8, and Sentinel-2 data

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Ecological Processes 2023年第1期12卷 402-414页

作者： alessandro Sebastiani Riccardo Salvati Fausto Manes Research Centre for Forestry and Wood(FL) Council for Agricultural Research and Economics(CREA)Via Valle Della Quistione 2700166 RomeItaly Research Institute On Terrestrial Ecosystems(IRET) National Research Council of Italy(CNR)Strada Provinciale 35d900015 Monterotondo(RM)Italy Presidential Estate of Castelporziano Via Pontina 69000128 RomeItaly Department of Environmental Biology Sapienza University of RomeP.Le Aldo Moro500185 RomeItaly

Background Leaf area index(LAI)is a key indicator for the assessment of the canopy’s processes such as net primary production and *** this reason,the LAI is often used as a key input parameter in ecosystem services’modeling,which is emerging as a critical tool for steering upcoming urban reforestation ***,LAI field measures are extremely time-consuming and require remarkable economic and human *** this context,spectral indices computed using high-resolution multispectral satellite imagery like Sentinel-2 and Landsat 8,may represent a feasible and economic solution for estimating the LAI at the city ***,as far as we know,only a few studies have assessed the potential of Sentinel-2 and Landsat 8 data doing so in Mediterranean forest *** fill such a gap,we assessed the performance of 10 spectral indices derived from Sentinel-2 and Landsat 8 data in estimating the LAI,using field measurements collected with the LI-COR LAI 2200c as a *** hypothesized that Sentinel-2 data,owing to their finer spatial and spectral resolution,perform better in estimating vegetation’s structural parameters compared to Landsat *** We found that Landsat 8-derived models have,on average,a slightly better performance,with the best model(the one based on NDVI)showing an R^(2) of 0.55 and NRMSE of 14.74%,compared to R^(2) of 0.52 and NRMSE of 15.15%showed by the best Sentinel-2 model,which is based on the *** models were affected by spectrum saturation for high LAI values(e.g.,above 5).Conclusion In Mediterranean ecosystems,Sentinel-2 and Landsat 8 data produce moderately accurate LAI estimates during the peak of the growing ***,the uncertainty introduced using satellite-derived LAI in ecosystem services’assessments should be systematically accounted for.

关键词： Mediterranean forest Leaf area index Field measurement Multispectral satellite imagery Sentinel-2 Landsat 8 Spectral vegetation index Global change

Comparison Between Deep Learning Models and Traditional Machine Learning Approaches for Facial Expression Recognition in Ageing Adults

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Journal of Computer Science & Technology 2020年第5期35卷 1127-1146页

作者： Andrea Caroppo alessandro Leone Pietro Siciliano Institute for Microelectronics and Microsystems National Research Council of ItalyLecce 73100Italy

Facial expression recognition is one'of the most active areas of research in computer vision since one of the non-verbal communication methods by which one understands the lnood/mental state of a person is the expression of ***,it has been used in various fields such as human-robot interaction,security,computer graphics animation,and ambient ***,it remains a challenging task since existing approaches lack generalizability and almost all studies ignore the effects of facial attributes,such as *** expression recognition even though the research indicates that facial expression inanifestation varies with ***,a lot of progress has been made in this topic and great improvements in classification task were achieved with the emergence of deep learning *** approaches have sliown how hierarchies of features can be directly learned from original data,thus avoiding classical hand designed feature extraction methods that generally rely on manual operations witli labelled ***,research papers systematically exploring tlu4 performance of existing deep architectures for the task of classifying expression of ageing adults are absent in the *** the present work a tentative to try this gap is done considering the performance of three recent deep convolutiorial neural networks models(VGG-16,AlexNet and GoogLeNet/Inception V1)and evaluating it on four different benchmark datcisets(FACES,Lifespan,CIFE,and FER2013)which also contain facial expressions performed by elderly *** the baseline,and with the aim of making a comparison,two traditional inacliine learning approaches based on handcrafted features extraction process are evaluated on the same *** out an exhaustive and rigorous experimentation focused on the concept of "transfer learning",which consists of replacing the output level of the deep architectures considered with new output levels appropriate to the number of classes(facial expressions),

关键词： computer vision deep learning facial expression machine learning ageing adult

Attitude Regulation With Bounded Control in the Presence of Large Disturbances With Bounded Moving Average

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IEEE/CAA Journal of Automatica Sinica 2022年第5期9卷 834-846页

作者： Ang Li alessandro Astolfi Ming Liu School of Astronautics Harbin Institute of TechnologyHarbin 150080China Department of Electrical and Electronic Engineering Imperial College LondonLondon SW72AZUK Dipartimento di Ingegneria Civile e Ingegneria Informatica University of Rome Tor VergataRoma 00133Italy IEEE

The attitude regulation problem with bounded control for a class of satellites in the presence of large disturbances,with bounded moving average,is solved using a Lyapunov-like *** analysis and design approaches are introduced in the case in which the underlying system is an integrator and are then applied to the satellite attitude regulation *** performance of the resulting closed-loop systems are studied in detail and it is shown that trajectories are ultimately bounded despite the effect of the persistent *** results on a model of a small satellite subject to large,but bounded in moving average,disturbances are presented.

关键词： control cubeSats robust attitude regulation ultimate boundedness

Vibration suppression of speed-controlled robots with nonlinear control

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Frontiers of Mechanical Engineering 2016年第2期11卷 204-212页

作者： Paolo BOSCARIOL alessandro GASPARETTO Dipartimento Politecnico di Ingegneria e Architettura (DPIA) University of Udine Via delle Scienze 206 Udine 33100 Italy

In this paper, a simple nonlinear control strategy for the simultaneous position tracking and vibration damping of robots is presented. The control is developed for devices actuated by speed-controlled servo drives. The conditions for the asymptotic stability of the closed-loop system are derived by ensuring its passivity. The capability of achieving improved trajectory tracking and vibration suppression is shown through experimental tests conducted on a three-axis Cartesian robot. The control is aimed to be compatible with most industrial applications given the simplicity of implementation, the reduced computational requirements, and the use of joint position as the only measured signal.

关键词： industrial robot nonlinear control vibrationdamping model-free control motion control