检索结果-南通市图书馆

On a Heuristic Viewpoint Concerning the Conversion and Transformation of Sound into Light

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of High Energy Physics, Gravitation and Cosmology 2024年第1期10卷 363-385页

作者： alessandro rizzo Brescia Italy

In the study of Terrestrial Gamma-ray Flashes (TGFs) and Sonoluminescence, we observe parallels with larger cosmic events. Specifically, sonoluminescence involves the rapid collapse of bubbles, which closely resembles gravitational collapse in space. This observation suggests the potential formation of low-density quantum black holes. These entities, which might be related to dark matter, are thought to experience a kind of transient evaporation similar to Hawking radiation seen in cosmic black holes. Consequently, sonoluminescence could be a valuable tool for investigating phenomena typically linked to cosmic scale events. Furthermore, the role of the Higgs boson is considered in this context, possibly connecting it to both TGFs and sonoluminescence. This research could enhance our understanding of the quantum mechanics of black holes and their relation to dark matter on Earth.

关键词： Planck Mass Gravity Light Phonons Phononic Field Vacuum Hydrodynamics Sonoluminescence Hawking Radiation Quantum Black Holes Theory of General Singularity

Combination therapy of dabrafenib plus trametinib in patients with BRAF^(V600E)-mutated biliary tract cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2021年第5期20卷 506-507页

作者： alessandro rizzo Angela Dalia Ricci Giovanni Brandi Division of Oncology Azienda Ospedaliero-Universitaria di Bolognavia Albertoni 15BolognaItaly

To the Editor: In the last decade, next-generation sequencing(NGS)-based molecular profiling has shed light on the molecular landscape of biliary tract cancer(BTC), revealing the presence of several potentially actionable mutations [1]. According to Clinical ***, there are at least 40 phase I to IV ongoing trials aimed at evaluating the role of targeted treatments in BTC, as monotherapy or in combination with other anticancer agents [2]. Early encouraging results have been observed with therapies targeting IDH mutations, FGFR fusions, HER family and, more recently, BRAF mutations [3].

关键词： BRAF cancer Clinical

Current status of the adjuvant therapy in uterine sarcoma: A literature review

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第14期7卷 1753-1763页

作者： alessandro rizzo Maria Abbondanza Pantaleo Maristella Saponara Margherita Nannini Department of Experimental Diagnostic and Specialty Medicine University of Bologna

Uterine sarcomas (US) are rare mesenchymal tumours accounting approximately for 3%–7% of all uterine cancers. Histologically, US are classified into mesenchymal tumours or mixed epithelial and mesenchymal tumours. The group of mesenchymal tumours includes uterine leiomyosarcoma (uLMS, 65% of cases), endometrial stromal sarcoma (ESS, 21%)– traditionally divided into low grade (LG-ESS) and high grade–undifferentiated uterine sarcoma (5%) and other rare subtypes such as alveolar or embryonal rhabdomyosarcoma. Despite the fact that several drugs demonstrated clinical activity in advanced or metastatic settings, the role of postoperative therapy in US remains controversial. In this review, we have summarised the current state of the art, including the chief trials on adjuvant treatment modalities in US, especially focusing on uLMS, LG-ESS and other rare histotypes.

关键词： Uterine sarcoma Uterine leiomyosarcoma Endometrial stromal sarcoma Adenosarcoma Adjuvant therapy Chemotherapy Radiotherapy

The Golden Ratio Theorem: A Framework for Interchangeability and Self-Similarity in Complex Systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Pure Mathematics 2023年第9期13卷 559-596页

作者： alessandro rizzo Brescia Italy

The Golden Ratio Theorem, deeply rooted in fractal mathematics, presents a pioneering perspective on deciphering complex systems. It draws a profound connection between the principles of interchangeability, self-similarity, and the mathematical elegance of the Golden Ratio. This research unravels a unique methodological paradigm, emphasizing the omnipresence of the Golden Ratio in shaping system dynamics. The novelty of this study stems from its detailed exposition of self-similarity and interchangeability, transforming them from mere abstract notions into actionable, concrete insights. By highlighting the fractal nature of the Golden Ratio, the implications of these revelations become far-reaching, heralding new avenues for both theoretical advancements and pragmatic applications across a spectrum of scientific disciplines.

关键词： Conservation Law Self-Similarity Interchangeability Golden Ratio Complex Systems Dynamic Exchange Structural Stability Mathematical Modeling Theoretical Framework P vs NP Millennium Problem

Is post-transplant chemotherapy feasible in liver transplantation for colorectal cancer liver metastases?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Communications 2020年第9期40卷 461-464页

作者： Giovanni Brandi Angela Dalia Ricci alessandro rizzo Chiara Zanfi Simona Tavolari Andrea Palloni Stefania De Lorenzo Matteo Ravaioli Matteo Cescon Department of Experimental Diagnostic and Specialty MedicineS.Orsola-Malpighi University HospitalBologna 40138Italy Department of General Surgery and Transplantation S.Orsola-Malpighi University HospitalBologna 40138Italy Center of Applied Biomedical Research S.Orsola-Malpighi University HospitalBologna 40138Italy

Dear Editor:In the last two decades,the indications of liver transplantation(LT)for primary and secondary hepatobiliary malignancies have been increasingly *** this attractive option still represents the“last court of appeal”in cancer patients,the role of LT is well established in hepatocellular carcinoma(HCC),where transplantation has also demonstrated a benefit for selected patients affected by peri-hilar cholangiocarcinoma,intrahepatic cholangiocarcinoma,and neuroendocrine tumors[1].Recently,the interest in LT in liver-limited stage IV colorectal cancer(CRC)has increased due to recent advances in transplantation techniques that have led to a re-evaluation of this approach.

关键词： colorectal cancer liver

Pancreatic mucinous cystadenocarcinoma in a patient harbouring BRCA1 germline mutation effectively treated with olaparib: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2020年第12期12卷 1456-1463页

作者： Mariacristina Di Marco Riccardo Carloni Stefania De Lorenzo Cristina Mosconi Andrea Palloni Elisa Grassi Daria Maria Filippini Angela Dalia Ricci alessandro rizzo alessandro Di Federico Donatella Santini Daniela Turchetti Claudio Ricci Carlo Ingaldi Laura Alberici Francesco Minni Rita Golfieri Giovanni Brandi Riccardo Casadei Department of Experimental Diagnosticand Specialty Medicine-DIMESSant'Orsola-Malpighi HospitalUniversity of BolognaBologna 40138Italy Division of Oncology Azienda Ospedaliero-Universitaria di BolognaBologna 40138Italy Radiology Unit Department of Diagnostic Medicine and PreventionSant'Orsola-Malpighi HospitalUniversity of BolognaBologna 40138Italy Medical Oncology Ospedale Degli InfermiFaenza 48018Italy Pathology Unit Sant'Orsola-Malpighi HospitalBologna 40138Italy Unit of Medical Genetics Sant'Orsola-Malpighi HospitalUniversity of BolognaBologna 40138Italy Division of Pancreatic Surgery Azienda Ospedaliero-Universitaria Di BolognaBologna 40138Italy Department of Internal Medicine and Surgery Alma Mater StudiorumUniversity of BolognaBologna 40138Italy

BACKGROUND Pancreatic mucinous cystadenocarcinoma(MCAC)is a rare malignancy with a poor prognosis when it presents metastases at *** to its very low incidence,there are no clear recommendations for the treatment of advanced ***(an oral PARP inhibitor)has been approved for the maintenance treatment of patients with metastatic pancreatic adenocarcinoma harbouring germline BRCA1/2 ***,we report the first case of a germline BRCA1 mutated unresectable MCAC which was effectively treated with *** SUMMARY A 41-year-old woman,without personal or family history of cancer,was diagnosed with ovarian and peritoneal metastases of *** underwent 12 cycles of gemcitabine plus oxaliplatin(GEMOX)obtaining a partial response and allowing radical *** year later,local recurrence was documented,and other 12 cycles of GEMOX were administered obtaining a complete *** years later,another local recurrence,not amenable to surgical resection,was *** started FOLFIRINOX(oxaliplatin,irinotecan,leucovorin and fluorouracil),obtaining a partial response after 8 *** the excellent response to platinum-based chemotherapy,BRCA testing was performed,and a BRCA1 germline mutation was *** was switched to maintenance olaparib due to chemotherapy-related toxicities and achieved an almost complete metabolic response,with a reduction in the diameter of the lesion,after three months of *** The current case suggests the beneficial effect of olaparib in BRCA mutated ***,further studies are required.

关键词： Mucinous cystadenocarcinoma Pancreatic cancer BRCA1 gene Olaparib Case report

Anti-TNF alpha in the treatment of ulcerative colitis:A valid approach for organ-sparing or an expensive option to delay surgery?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第17期20卷 4839-4845页

作者： Gianluca rizzo Daniela Pugliese alessandro Armuzzi Claudio Coco Department of Surgical Sciences Complesso Integrato ColumbusCatholic University of the Sacred Heart00168 RomeItaly Internal Medicine and Gastroenterology Unit Complesso Integrato ColumbusCatholic University of the Sacred Heart00168 RomeItaly

Ulcerative colitis (UC) is an inflammatory bowel disease affecting large bowel with variable clinical course. The history of disease has been modified by the introduction of biologic therapy, in particular Infliximab (IFX), that has demonstrated efficacy in inducing fast symptoms remission, promoting mucosal healing and maintaining long-term remission. However, surgery is still needed for UC patients: in case of failure of medical therapy and if acute complications or a malignancy occurred. Surgical treatment is associated with a short-term post-operative mortality and morbidity respectively of 0%-4% and 30%. In this study we systematically analyzed: the role of IFX in reducing the colectomy rate, the risk of post-operative morbidity in pre-operatively IFX-treated patients and the cost-effectiveness of IFX therapy. Four of 5 analyzed randomized controlled trials demonstrated that therapy with IFX significantly reduces the colectomy rate. Moreover, pre-operative treatment with IFX doesn’t seem to increase post-operative infectious complications. By an economic point of view, the cost-effectiveness of IFX-therapy was demonstrated for UC patients suffering from moderate to severe UC in a study based on a cost estimation of the National Health Service of England and Wales. However, the argument is debated.

关键词： Ulcerative colitis Infliximab Colectomy Post-operative complications Cost-effectiveness Inflammatory bowel disease

Fruit ripeness classification:A survey

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Artificial Intelligence in Agriculture 2023年第1期7卷 44-57页

作者： Matteo rizzo Matteo Marcuzzo alessandro Zangari Andrea Gasparetto Andrea Albarelli Ca’Foscari Department of Environmental Sciences Informatics and StatisticsVia Torino 155Mestre(VE)30172Italy Ca’Foscari Department of Management Cannaregio 873Fondamenta San GiobbeVenice 30121Italy

Fruit is a key crop in worldwide agriculture feeding millions of *** standard supply chain of fruit products involves quality checks to guarantee freshness,taste,and,most of all,*** important factor that determines fruit quality is its stage of *** is usually manually classified by field experts,making it a labor-intensive and error-prone ***,there is an arising need for automation in fruit ripeness *** automatic methods have been proposed that employ a variety of feature descriptors for the food item to be *** learning and deep learning techniques dominate the top-performing ***,deep learning can operate on raw data and thus relieve the users from having to compute complex engineered features,which are often *** this survey,we review the latest methods proposed in the literature to automatize fruit ripeness classification,highlighting the most common feature descriptors they operate on.

关键词： Fruit ripeness classification Machine learning Deep learning

Efficiency in hydrocarbon degradation and biosurfactant production by Joostella sp.A8 when grown in pure culture and consortia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2018年第5期30卷 115-126页

作者： Carmen rizzo alessandro Ciro Rappazzo Luigi Michaud Emilio De Domenico Carlos Rochera Antonio Camacho Angelina Lo Giudice Department of Chemical BiologicalPharmaceutical and Environmental Sciences(ChiBioFarAm)University of MessinaViale Ferdinando Stagno d'Alcontres 3198166 MessinaItaly Institute for the Coastal Marine Environment National Research Council(IAMC-CNR)Spianata San Raineri 8698122 MessinaItaly Cavanilles Institute for Biodiversity and Evolutionary Biology University of ValenciaCarrer del Catedratic Jose Beltran Martinez 246980 PaternaValenciaSpain Regional Centre for Water Studies(CREA) University of Castilla-La ManchaC/Altagracia 5013071 Ciudad RealSpain

Joostella strains are emerging candidates for biosurfactant production. Here such ability was analyzed for Joostella strain A8 in comparison with Alcanivorax strain A53 and Pseudomonas strain A6, all previously isolated from hydrocarbon enrichment cultures made of polychaete homogenates. In pure cultures Joostella sp. A8 showed the highest stable emulsion percentage（78.33%）, hydrophobicity rate（62.67%）, and an optimal surface tension reduction during growth in mineral medium supplemented with diesel oil（reduction of about 12 mN/m）, thus proving to be highly competitive with Alcanivorax and Pseudomonas strains. During growth in pure culture different level of biodegradation were detected for Alcanivorax strain A53（52.7%）,Pseudomonas strain A6（38.2%） and Joostella strain A8（26.8%）. When growing in consortia,isolates achieved similar abundance values, with the best efficiency that was observed for the Joostella-Pseudomonas co-culture. Gas-chromatographic analysis revealed an increase in the biodegradation efficiency in co-cultures（about 90%）, suggesting that the contemporary action of different bacterial species could improve the process. Results were useful to compare the efficiencies of well-known biosurfactant producers（i.e. Pseudomonas and Alcanivorax representatives） with a still unknown biosurfactant producer, i.e. Joostella, and to confirm them as optimal biosurfactant-producing candidates.

关键词： Joostella Biosurfactants Co-cultures Hydrocarbon degradation Biodegradation efficiency