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Effects of calibration process on the simulation of rear-end conflicts at roundabouts

Journal of Traffic and Transportation Engineering(English Edition) 2019年第2期6卷 175-184页

作者： Vincenzo Gallelli Giuseppe Guido alessandro Vitale Rosolino Vaiana Department of Civil Engineering University of Calabria

A methodology for calibrating and validating VISSIM simulation model is presented that allows to replicate the observed vehicles conflicts. A roundabout case study has been selected to test the usefulness of a combined approach of VISSIM simulation package and the surrogate safety assessment model(SSAM) for providing reliable estimates of traffic conflicts. Safety performance has been assessed from the field by video-recording vehicle interactions at the roundabout, and then expressed in terms of time to collision(TTC)*** proposed calibration procedure has been performed by a multistage methodology involving microscopic drivers' car following behavior parameters to enhance the correlation between observed and simulated queue lengths at the roundabout's entries. The calibration procedure is based on a statistical screening of inputs leading to a linear expression relating significant parameters to the queue length. The best estimates of the model's parameters have been determined using a genetic algorithm *** spatial distribution of the rear-end conflicts and the TTC values determined by SSAM have been finally compared with the observed ones to analyze the capability of the model of replicating rear-end *** results suggest to this calibration procedure impacts positively on the estimate of the safety performance measures obtained through the simulation *** the good results in the evaluation of the model's accuracy, the simulation seems to fail in reproducing the traffic phenomena linked to unusual driving behavior, and therefore it is not able to replicate forced drivers' maneuvers that can lead to a conflict situation.

关键词： Simulation Safety performance Unmanned aerial vehicle Roundabouts Traffic conflicts

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Disseminated intravascular coagulation after splenic artery aneurysm coils embolization:an unexpected surprise

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Gastroenterology Report 2023年第1期11卷 551-553页

作者： Marco Biolato alessandro D’Errico Fiammetta Maria Rognoni Giuseppe Marrone Luca Laurenti alessandro Cina Antonio Grieco Department of Medical and Surgical Sciences Fondazione Policlinico Universitario Agostino Gemelli IRCCSRomeItaly Institute of Internal Medicine Catholic University of the Sacred HeartRomeItaly Department of Diagnostic imaging Radiation oncology and HematologyFondazione Policlinico Universitario Agostino Gemelli IRCCSRomeItaly Institute of Hematology Catholic University of the Sacred HeartRomeItaly Institute of Radiology Catholic University of the Sacred HeartRomeItaly

Introduction The Society for Vascular Surgery recommends treating nonruptured splenic artery aneurysms(SAAs)of>3 cm with a demonstrable increase in size or with associated symptoms[1].Percutaneous intervention with embolization coils or covered stents has become popular due to its high technical success rates and low morbidity[2,3].

关键词： Surgery artery coils

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*** volcano high-resolution topography:airborne LiDAR modelling validated by GPS data

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International Journal of Digital Earth 2016年第7期9卷 710-732页

作者： Marina Bisson Claudia Spinetti Marco Neri alessandro Bonforte Istituto Nazionale di Geofisica e Vulcanologia via della Faggiola 32PisaItaly Istituto Nazionale di Geofisica e Vulcanologia Centro Nazionale Terremotivia di Vigna MurataRomeItaly Istituto Nazionale di Geofisica e Vulcanologia Sezione di CataniaOsservatorio EtneoPiazza RomaCataniaItaly

High-resolution digital topography is essential for land management and planning in any type of territory as well as the reproduction of the Earth surface in a geocoded digital format that allows several Digital Earth *** a volcanic environment,Digital Elevation Models are a valid reference for multi-temporal analyses aimed to observe frequent changes of a volcano edifice and for the relative detailed morphological and structural *** the first time,a DTM(Digital Terrain Model)and a DSM(Digital Surface Model)covering the entire *** volcano(Italy)derived from the same airborne Light Detection and Ranging(LiDAR)are here *** than 250 million 3D LiDAR points have been processed to distinguish ground elements from natural and anthropic *** end product is the highly accurate representation of *** landscape(DSM)and ground topography(DTM)dated *** models have a high spatial resolution of 2 m and cover an area of 620 *** DTM has been validated by GPS ground control *** vertical accuracy has been evaluated,resulting in a root-mean-square-error of±0.24 *** DTM is available as electronic supplement and represents a valid support for various scientific studies.

关键词： Airborne LiDAR GPS DEM Mt.Etna

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An Advanced Prediction Mechanism to Analyse Pore Geometry Shapes and Identification of Blocking Effect in VRLA Battery System

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International Journal of Automation and computing 2017年第1期14卷 21-32页

作者： alessandro Mariani Kary Thanapalan Peter Stevenson Jonathan Williams Faculty of Computing Engineering and Science University of South Wales Pontypridd CF37 1DL UK Yuasa Battery (UK) Ltd Rassau Industrial Estate Ebbw Vale NP23 5SD UK

The aim of this investigation is to define a model of an alternating current impedance response that can identify the state of health of a porous electrode due to the blocked diffusion effect. To identify and simulate different pore geometries, an analytical differential equations system was studied. Standard and low performance battery products were simulated by the model and validated with electrochemical impedance spectroscopy （EIS） experimental data. The correlation between pore structure geometries and the related battery efficiency is also addressed. This investigation may clarify the possible reasons for low performance batteries. Identifying the benchmark pore geometry, parameters may be useful for the battery producers to improve the efficiency of their products. Various recovery methods are also included in this investigation to disperse the build-up of lead sulphate crystal that limits the electrolysis process in the low performance batteries.

关键词： Positive active material crystal structure valve regulated lead acid (VRLA) batteries modelling estimation and recoverytechniques.

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Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B

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World Journal of Gastroenterology 2007年第4期13卷 525-531页

作者： Giada Sebastiani alessandro Vario Maria Guido Alfredo Alberti Depart-ment of Clinical and Experimental Medicine University of Pado-va Padova Italy Department of Oncological and Surgical Sciences University of Padova Padova Italy

AIM： To assess the performance of several noninvasive markers and of our recently proposed stepwise combination algorithms to diagnose significant fibrosis （F ≥ 2 by METAVIR） and cirrhosis （F4 by METAVIR） in chronic hepatitis B （CHB）.METHODS： One hundred and ten consecutive patients （80 males, 30 females, mean age： 42.6 ± 11.3） with CHB undergoing diagnostic liver biopsy were included. AST-to-Platelet ratio （APRI）, Forns＇ index, AST-to-ALT Ratio, Goteborg University Cirrhosis Index （GUCD, Hui＇s model and Fibrotest were measured on the day of liver biopsy. The performance of these methods and of sequential algorithms combining Fibrotest, APRI and biopsy was defined by positive （PPV） and negative （NPV） predictive values, accuracy and area under the curve （AUC）. RESULTS： PPV for significant fibrosis was excellent （100%） with Forns and high （〉 92%） with APR1, GUCI, Fibrotest and Hui. However, significant fibrosis could not be excluded by any marker （NPV 〈 65%）. Fibretest had the best PPV and NPV for cirrhosis （87% and 90%, respectively）. Fibrotest showed the best AUC for both significant fibrosis and cirrhosis （0.85 and 0.76, respectively）. Stepwise combination algorithms of APR1, Fibrotest and biopsy showed excellent performance （0.96 AUC, 100% NPV） for significant fibrosis and 0.95 AUC, 98% NPV for cirrhosis, with 50%-80% reduced need for liver biopsy. CONCLUSION： In CHB sequential combination of APRI, Fibrotest and liver biopsy greatly improves the diagnostic performance of the single non-invasive markers. Need for liver biopsy is reduced by 50%-80% but cannot be completely avoided. Non-invasive markers and biopsy should be considered as agonists and not antagonists towards the common goal of estimating liver fibrosis.

关键词： Chronic hepatitis B Hepatic fibrosis Liverbiopsy Non-invasive markers Stepwise combinationalgorithms

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The Nature of “Natural Disasters”: Survivors’ Explanations of Earthquake Damage

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International Journal of Disaster Risk Science 2019年第3期10卷 293-305页

作者： alessandro Massazza Chris R.Brewin Helene Joffe Department of Clinical Educational and Health PsychologyUniversity College London

The distinction between natural and human-made disasters is ingrained in everyday language. Disaster scientists have long been critical of this dichotomy. Nonetheless,virtually no attention has been paid to how disaster survivors conceptualize the causes of the disasters they experience. In this mixed-methods longitudinal study, 112 survivors of the2016–2017 Central Italy earthquakes completed questionnaires 3 and 16 months following the earthquakes, with the aim of assessing attributions of blame for the earthquake damage. In-depth interviews were also conducted with 52 participants at the 3-month mark to explore representations of causation for the earthquake damage. The distinction between disasters caused by nature and disasters caused by humans was not supported by survivors of the earthquake. In the longitudinal surveys, building firms and the State were assigned as much blame as nature for the earthquake damage, at both 3 months and 16 months after the *** this complexity, in the interviews, the causes of the earthquake damage, rather than being understood as purely natural, were perceived as a complex mosaic composed of political, technological, natural, and moral *** empirical work shows that disaster survivors combine both nature-based and human-based explanations of disasters, rather than subscribing to one or the other. These findings have practical implications for disaster risk reduction and response.

关键词： Amatrice Attributions Disaster causes Disaster survivors Human-made disasters Natural disasters 2016–2017 Central Italy earthquakes

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Super-resolution GANs for upscaling unplanned urban settlements from remote sensing satellite imagery - the case of Chinese urban village detection

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International Journal of Digital Earth 2023年第1期16卷 2623-2643页

作者： alessandro Crivellari Hong Wei Chunzhu Wei Yuhui Shi Department of Computer Science and Engineering SouthernUniversity of Science and TechnologyShenzhenPeople’s Republic of China Ministry of Education Ecological Field Station for East Asian Migratory Birds Department of Earth System ScienceInstitute for Global Change StudiesTsinghua UniversityBeijingPeople’s Republic of China School of Geography and Planning Sun Yat-sen UniversityGuangzhouPeople’s Republic of China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiPeople’s Republic of China

The semantic segmentation of informal urban settlements represents an essential contribution towards renovation strategies and reconstruction *** this context,however,a big challenge remains unsolved when dealing with incomplete data acquisitions from multiple sensing devices,especially when study areas are depicted by images of different *** practice,traditional methodologies are directed to downgrade the higher-resolution data to the lowest-resolution measure,to define an overall homogeneous dataset,which is however ineffective in downstream segmentation activities of such crowded unplanned urban *** this purpose,we hereby tackle the problem in the opposite direction,namely upscaling the lower-resolution data to the highest-resolution measure,contributing to assess the use of cutting-edge super-resolution generative adversarial network(SR-GAN)*** experimental novelty targets the particular case involving the automatic detection of‘urban villages’,sign of the quick transformation of Chinese urban *** aligning image resolutions from two different data sources(Gaofen-2 and Sentinel-2 data),we evaluated the degree of improvement with regard to pixel-based landcover segmentation,achieving,on a 1 m resolution target,classification accuracies up to 83%,67%and 56%for 4x,8x,and 10x resolution upgrades respectively,disclosing the advantages of artificially-upscaled images for segmenting detailed characteristics of informal settlements.

关键词： SR-GAN resolution upscaling informal settlements urban villages cross-sensor analytics

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Laparoscopic pancreaticoduodenectomy: a descriptive and comparative review

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Chinese Journal of Cancer Research 2015年第4期27卷 368-375页

作者： Justin Merkow alessandro Paniccia Barish H.Edil Department of Surgery University Of Colorado

Laparoscopic pancreaticoduodenectomy（LPD） is an extremely challenging surgery. First described in 1994, it has been slow to gain in popularity. Recently, however, we have seen an increase in the number of centers performing this operation, including our own institution, as well as an increase in the quantity of published data. The purpose of this review is to describe the current status of LPD as described in the literature. We performed a literature search in the Pub Med database using Me SH terms ＂laparoscopy＂ and ＂pancreaticoduodenectomy＂. We then identified articles in the English language with over 20 patients that focused on LPD only. Review articles were excluded and only one article per institution was used for descriptive analysis in order to avoid overlap. There were a total of eight articles meeting review criteria, consisting of 492 patients. On descriptive analysis we found that percent of LPD due to high-grade malignancy averaged 47% over all articles. Average operative time was 452 minutes, blood loss 369 cc＇s, pancreatic leak rate 15%, delayed gastric emptying 8.6%, length of hospital stay 9.4 days, and short term mortality 2.3%. Comparison studies between open pancreaticoduodenectomy（OPD） and LPD suggested decreased blood loss, longer operative time, similar post-operative complication rate, decreased pain, and shorter hospital length of stay for LPD. There was also increased number of lymph nodes harvested and similar margin free resections with LPD in the majority of studies. LPD is a safe surgery, providing many of the advantages typically associated with laparoscopic procedures. We expect this operation to continue to gain in popularity as well as be offered in increasingly more complex cases. In future studies, it will be beneficial to look further at the oncologic outcome data of LPD including survival.

关键词： Laparoscopic laparoscopy pancreaticoduodenectomy whipple review laparoscopic vs.open

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ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients

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World Journal of Gastroenterology 2010年第6期16卷 732-739页

作者： lsabel Hostettler Inti Zlobec Luigi Terracciano alessandro Lugli Institute for Pathology University Hospital of Basel

AIM:To analyze the expression of 8 putative cancer stem cell(CSC) markers within colorectal cancer tumor buds and to determine their prognostic impact in patients with this disease. METHODS:Immunohistochemistry was performed on 101 colorectal cancer resections for CK22(to identify tumor buds) as well as CD133,CD166,CD24,CD44s,CD90,EpCAM,ALDH1,and ABCG5,and their expression within tumor buds was evaluated. RESULTS:CD90,CD44s,and CD133 expression in tumor buds was found in less than 5%of all cases. ALDH1,CD24,CD166 were expressed in 16.5%,16.2%,and 34%cases,respectively,while ABCG5 and EpCAM expression was more frequent and found in 35%and 69%of cases,*** the 8 markers studied,EpCAM and ABCG5 positivity in tumor buds were significantly associated with poor prognosis(P=0.023,P=0.038,respectively) in multivariable analysis with pT and pN classificationP=0.048;hazard ratio(HR) :2.64;95%CI:1.0-6.9,for EpCAM and P=0.029;HR:2.22;95%CI:1.0-4.5,for *** survival time was particularly striking for lymph node-negative patients with ABCG5-positive buds(P<0.001) . CONCLUSION:Expression of putative stem cell markers EpCAM and ABCG5 within the tumor buds of colorectal cancer are frequently noted and are associated with poor prognosis.

关键词： Colorectal cancer Cancer stem cells Tumor budding ABCG5 Prognosis

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Continuous generating grinding method for beveloid gears and analysis of grinding characteristics

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Advances in Manufacturing 2022年第3期10卷 459-478页

作者： Bing Cao Guo-Long Li alessandro Fortunato Heng-Xin Ni College of Mechanical and Vehicle Engineering Chongqing UniversityChongqing 400030People's Republic of China State Key Laboratory of Mechanical Transmission Chongqing UniversityChongqing 400044People's Republic of China Department of Industrial Engineering(DIN) Alma Mater StudiorumUniversity of BolognaViale Risorgimento 2Bologna 40136Italy

Continuous generating grinding has become an important gear processing method owing to its high efficiency and *** this study,an adaptive design model is proposed for the continuous generation of beveloid gears in common gear grinding *** on this model,a method for determining the installation position and grinding kinematics is developed alongside an analytical meshing model for grinding contact trace and derivation of key grinding *** combining these aspects,a general mathematical model for the continuous generation of beveloid gears is presented,comprising the entire grinding process from worm wheel dressing to the evaluation of grinding *** effects of the worm and dressing wheel parameters on the grinding deviation were analysed,facilitating the development of an approach to improve the grinding *** presented procedure represents a novel design method for the continuous generation of beveloid gears in common gear grinding machines,facilitating the appropriate selection of worm and dressing wheel parameters.

关键词： Beveloid gears Continuous generating grinding Meshing model Kinematics model

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