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Hepatoprotective effect of leaves of Erythroxylum monogynum *** paracetamol induced toxicity

Asian Pacific Journal of Tropical Biomedicine 2013年第11期3卷 877-881页

作者： Sabeena Hussain Syed ajay gajanan namdeo Department of Pharmacognosy Bharati Vidyapeeth Deemed UniversityPoona College of Pharmacy

Objective:To investigate the hepatoprotective activity of methanolic extract of leaves of Erythroxylum monogynum(***)on paracetamol induced ***:Methanolic extract of leaves of *** was given in doses of 100 mg/kg,200 mg/kg and 400 mg/kg for 7 d and toxicity was induced by paracetamol(2 mg/kg)on Day ***(50 mg/kg)was used as reference *** 24 h of toxicity induction blood samples were collected from retro-orbital plexsus and analyzed for serum parameters like serum glutamic pyruvic transaminase,serum glutamic oxaloacetate transaminse,alkaline phosphatase and total *** isolated were studied for histopathological ***:Phytochemical analysis of methanolic extract of *** leaves showed the presence of carbohydrates,flavonoids,phenols and *** administration of this extract restored the elevated levels serum markers as compared to toxic group which is also confirmed by the histopathological changes ***:The present study showed that methanolic extract of leaves of *** possess hepatoprotective action against paracetamol induced hepatotoxicity.

关键词： Erythroxylum monogynum Hepatoprotection Paracetamol Silymarin

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Self-lubricating bidirectional carbon fiber reinforced smart aluminum composites by squeeze infiltration process

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Journal of Materials Science & Technology 2019年第11期35卷 2559-2569页

作者： K.M.Sree Manu L.ajay Raag T.P.D.Rajan B.C.Pai Vijay Petley Shweta namdeo Verma CSIR-National Institute for Interdisciplinary Science and Technology TrivandrumIndia Gas Turbine Research Establishment(GTRE) BangaloreIndia

Self-lubrication is one of the smart material properties required for producing components with enhanced wear resistance and low coefficient of ***(BD)satin weave polyacrylonitrile(PAN)based carbon fiber(Cf)fabric preform was successfully infiltrated with Al 6061 alloy by squeeze infiltration *** infiltrated composite shows uniform distribution of carbon fibers in the matrix with the elimination of porosities,fiber damage and close control on the formation of deleterious aluminum carbide(Al4C3)***/Al composite exhibits remarkable wear resistance compared to unreinforced alloy due to the formation of self-lubricating tribolayer on the pin surface,which intercepts the contact of matrix metal to counter *** BD carbon fiber enhanced the hardness and compressive strength of the composite by restraining the plastic flow behavior of *** resolution transmission electron microscopy shows the presence of Al2O3 and MgAl2O4 spinel,confirmed by EDS and SAD pattern,at the composite *** composite shows a lower density of 2.16 g/cm^3 which is a major ad vantage for weight reduction compared to the monolithic alloy(2.7 g/cm^3).

关键词： Metal matrix composites Squeeze infiltration Aluminum Carbon fiber fabric Tribology Microstructure

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