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Contribution of phylogenetics to understanding the evolution and epidemiology of dengue virus

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Animal Models and Experimental Medicine 2022年第5期5卷 410-417页

作者： xi yu Gong Cheng Tsinghua-Peking Center for Life Sciences School of MedicineTsinghua UniversityBeijingChina Institute of Infectious Diseases Shenzhen Bay LaboratoryShenzhenChina Institute of Pathogenic Organisms Shenzhen Center for Disease Control and PreventionShenzhenChina School of Life Sciences Tsinghua UniversityBeijingChina

Dengue virus(DENV)is one of the most important arboviral pathogens in the tropics and subtropics,and nearly one-third of the world's population is at risk of *** transmission of DENV involves a sylvatic cycle between nonhuman primates(NHP)and Aedes genus mosquitoes,and an endemic cycle between human hosts and predominantly Aedes *** belongs to the genus Flavivirus of the family Flaviviridae and consists of four antigenically distinct serotypes(DENV-1-4).Phylogenetic analyses of DENV have revealed its origin,epidemiology,and the drivers that determine its molecular evolution in *** review discusses how phyloge-netic research has improved our understanding of DENV evolution and how it affects viral ecology and improved our ability to analyze and predict future DENV emergence.

关键词： dengue virus(DENV) evolution flavivirus phylogenetics

Isothermal Crystallization of iPP in Environment-friendly Diluents:Effect of Binary Diluents and Crystallization Temperature on Crystallization Kinetics

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Chinese Journal of Polymer Science 2019年第6期37卷 617-626页

作者： yu-Jie Wang Su-Ying Yan Zhi-Ping Zhao Zhen-yu xi School of Chemistry and Chemical Engineering Beijing Institute of Technology Environmental Protection Research Institute Beijing Research Institute of Chemical IndustrySINOPEC

The growing demand for non-toxic solvents for membrane preparation has motivated the studies for green and sustainable alternatives of solvents. The effect of droplet isothermal growth within the liquid-liquid phase separation region on isothermal spherulitic growth rate of isotactic polypropylene(iPP) was investigated. The results showed that the droplets grew up at a rate of 0.0172 μm·s^(-1). The larger droplets slowed down the isothermal spherulitic growth rate of iPP. Higher mass ratio of carnauba wax(Cwax)/soybean oil(SO)resulted in faster droplet growth due to weak interaction with polymers. The isothermal crystallization behaviors of iPP in environmentfriendly binary diluents consisting of Cwax and SO mixture were further investigated experimentally using polarized optical *** was demonstrated that the isothermal spherulitic growth rate of iPP in diluents decreased nonlinearly with the increasing crystallization temperature. Compared with virgin iPP, isothermal spherulitic growth rate of iPP in SO diluent was significantly slowed down. The spherulitic growth was further retarded after the addition of Cwax in mixed diluents, resulting in a lower crystallization rate than that in SO. Moreover, the crystal form of iPP membranes was found to be α type through the characterization of small angle X-ray scattering and wide angle X-ray diffraction.

关键词： Isotactic polypropylene Carnauba wax Isothermal crystallization kinetics PP membrane

A molecular mechanics approach for analyzing tensile nonlinear deformation behavior of single-walled carbon nanotubes

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Acta Mechanica Sinica 2007年第6期23卷 663-671页

作者： yu Wang Daining Fang ai Kah Soh Bin Liu Department of Engineering Mechanics Tsinghua University Beijing 100084 China Department of Mechanical Engineering University of Hong Kong Hong Kong China

In this paper, by capturing the atomic information and reflecting the behaviour governed by the nonlinear potential function, an analytical molecular mechanics approach is proposed. A constitutive relation for single-walled carbon nanotubes （SWCNT＇s） is established to describe the nonlinear stress-strain curve of SWCNT＇s and to predict both the elastic properties and breaking strain of SWCNT＇s during tensile deformation. An analysis based on the virtual internal bond （VIB） model proposed by P. Zhang et al. is also presented for comparison. The results indicate that the proposed molecular mechanics approach is indeed an acceptable analytical method for analyzing the mechanical behavior of SWCNT＇s.

关键词： Molecular mechanics approach Carbon nanotube Constitutive relation Young's modulus

Wireless Powered IoE for 6G: Massive Access Meets Scalable Cell-Free Massive MIMO

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China Communications 2020年第12期17卷 92-109页

作者： Shuaifei Chen Jiayi Zhang yu Jin Bo ai School of Electronic and Information Engineering Beijing Jiaotong UniversityBeijing 100044China State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong UniversityBeijing 100044China Henan Joint International Research Laboratory of Intelligent Networking and Data Analysis Zhengzhou UniversityZhengzhou 450001China

A key challenge to the scalable deployment of the energy self-sustainability(ESS)Internet of Everything(IoE)for sixth-generation(6G)networks is juggling massive connectivity and high spectral efficiency(SE).Cell-free massive multiple-input multiple-output(CF mMIMO)is considered as a promising solution,where many wireless access points perform coherent signal processing to jointly serve the ***,massive connectivity and high SE are difficult to obtain at the same time because of the limited pilot *** solve this problem,we propose a new framework for ESS IoE networks where the user activity detection(UAD)and channel estimation are decoupled.A UAD detector based on deep convolutional neural networks,an initial access scheme,and a scalable power control policy are proposed to enable the practical scalable CF mMIMO *** derive novel and exact closed-form expressions of harvested energy and SE with maximum ratio(MR)*** local partial minimum mean-square error and MR combining,simulation results prove that the proposed framework can serve more users,improve the SE performance,and achieve better user fairness for the considered ESS IoE networks.

关键词： 6G network cell-free massive MIMO energy self-sustainability Internet of Everything

Investigation ofβ—‑decay half‑life and delayed neutron emission with uncertainty analysis

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Nuclear Science and Techniques 2023年第1期34卷 111-123页

作者： yu‑Feng Gao Bo‑Shuai Cai Cen‑xi yuan Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China

β-decay half-life and β-delayed neutron emission(βn) are of great importance in the development of basic science and industrial applications, such as nuclear physics and nuclear energy, where β--decay plays an important role. Many theoretical models have been proposed to describe β-decay half-lives, whereas the systematic study of βn is still rare. This study aimed to investigate β--decay half-lives and βn probabilities through analytical formulas and by comparing them with experimental data. Analytical formulas for β--decay properties have been proposed by considering prominent factors, that is, decay energy,odevity, and the shell effect. The bootstrap method was used to simultaneously evaluate the total uncertainty on calculations,which was composed of statistic and systematic uncertainties. β--decay half-lives, βn probabilities, and the corresponding uncertainties were evaluated for the neutron-rich region. The experimental half-lives were well reproduced. Additional predictions are also presented with theoretical uncertainties, which helps to better understand the disparity between the experimental and theoretical results.

关键词： Neutron-rich nucleus -delayed neutron emissions Bootstrap method

Microstructure and properties of 1100 MPa grade low-carbon hot-rolled steel by laser welding

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Journal of Iron and Steel Research International 2018年第2期25卷 228-234页

作者： Chen Dong ai-min Zhao xi-tao Wang Qi-hang Pang Hui-bin Wu Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083 China Engineering Research Institute University of Scienceand Technology Beijing Beijing 100083 China

The microstructure and mechanical properties of the butt joint of 1100 MPa grade hot-rolled low-carbon steel by laser welding were investigated by scanning electron microscopy, micro-hardness and tensile tests. The yield strength and tensile strength of the laser welded joint reached 100.2 and 99.5% of the base material （BM）, respectively. However, the elongation of the welded joint only reached about 60% of BM. The lowest and highest hardness areas both existed in the incomplete recrystallization zone. The width of the softened area of the welded joint is about 240-260 pro. The element distribution has no obvious change for C, Cr, Si, Mn, Ti, etc.

关键词： Hot-rolled steel Laser welding Microstructure Mechanical property Element distribution

A novel machine learning approach(svm Somatic) to distinguish somatic and germline mutations using next-generation sequencing data

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Zoological Research 2021年第2期42卷 246-249页

作者： yu-Fang Mao xi-Guo yuan yu-Peng Cun School of Computer Science and Technology Xidian UniversityXi'anShaanxi 710071China iFlora Bioinformatics Center Germplasm Bank of Wild SpeciesKunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China

DEAR EDITOR,Somatic mutations are a large category of genetic variations,which play an essential role in tumorigenesis. Detection of somatic single nucleotide variants(SNVs) could facilitate downstream analysis of tumorigenesis. Many computational methods have been developed to detect SNVs, but most require normal matched samples to differentiate somatic SNVs from the normal state, which can be difficult to obtain.

关键词： data A novel machine learning approach svm Somatic

Multifunctional roles of inflammation and its causative factors in primary liver cancer:A literature review

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World Journal of Hepatology 2023年第12期15卷 1258-1271页

作者： Hong-Jin Chen Ting-xiong Huang yu-xi Jiang xiong Chen ai-Fang Wang Department of Pharmacology School of Basic Medical SciencesTranslational Medicine Research CenterGuizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina School of Clinical Medical Translational Medicine Research CenterGuizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina Zhejiang Provincial Key Laboratory of Medical Genetics Key Laboratory of Laboratory MedicineMinistry of EducationWenzhou 325035Zhejiang ProvinceChina Department of Endocrinology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina Department of Endocrinology The People's Hospital of YuhuanThe Yuhuan Branch of The First Affiliated Hospital of Wenzhou Medical UniversityYuhuan 317600Zhejiang ProvinceChina

Primary liver cancer is a severe and complex disease,leading to 800000 global deaths *** evidence suggests that inflammation is one of the critical factors in the development of hepatocellular carcinoma(HCC).Patients with viral hepatitis,alcoholic hepatitis,and steatohepatitis symptoms are at higher risk of developing ***,not all inflammatory factors have a pathogenic function in HCC *** current study describes the process and mechanism of hepatitis development and its progression to HCC,particularly focusing on viral hepatitis,alcoholic hepatitis,and ***,the roles of some essential inflammatory cytokines in HCC progression are described in addition to a summary of future research directions.

关键词： Inflammation Primary liver cancer Hepatocellular carcinoma Nonalcoholic fatty liver disease Hepatitis virus

Remote Preparation of an Entangled State in Nonideal Conditions

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Communications in Theoretical Physics 2006年第2X期46卷 221-224页

作者： CHEN ai-xi DENG Li LI Jia-Hua ZHAN Zhi-Ming Department of Physics East China Jiaotong University Nanchang 330013 China Center of Cold Atom Physics the Chinese Academy of Sciences Wuhan 430071 China Department of Physics Huazhong University of Science and Technology Wuhan 430074 China 4Department of Physics Jianghan University Wuhan 430056 China

In this paper, the theoretical investigation of remote preparation of an entangledstate is studied in nonideal conditions. Our studies include two parts. In the first part, we consider the remote state preparation （RSP） of an entangled state through two equally noisy quantum channel states, namely, a mixture of Bell states. Studies show there is a particular mixed-state channel for which all pure entangled states remain entangled after this inexact RSP. In the second part, we suppose that noises which quantum channels suffer from can be expressed as the Lindblad operators. The master equation of the system can be expressed in the Lindblad form. Through solving the master equation, we calculate the fidelity as a function of decoherence rates and parameters of the state to be prepared. For a given entangled state, we investigate the influence of different types of noises on the fidelity.

关键词： remote state preparation fidelity entanglement