Multifunctional roles of inflammation and its causative factors in primary liver cancer:A literature review
作者机构：Department of PharmacologySchool of Basic Medical SciencesTranslational Medicine Research CenterGuizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina School of Clinical MedicalTranslational Medicine Research CenterGuizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina Zhejiang Provincial Key Laboratory of Medical GeneticsKey Laboratory of Laboratory MedicineMinistry of EducationWenzhou 325035Zhejiang ProvinceChina Department of EndocrinologyThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina Department of EndocrinologyThe People's Hospital of YuhuanThe Yuhuan Branch of The First Affiliated Hospital of Wenzhou Medical UniversityYuhuan 317600Zhejiang ProvinceChina
出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)
年 卷 期：2023年第15卷第12期
页 面：1258-1271页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by the National Natural Science Foundation of China,No.82260567 Science and Technology Fund of Guizhou Provincial Health Commission,No.gzwkj2022-082 Excellent Young Talents Plan of Guizhou Medical University,No.2023(112) Taizhou Social Development Science and Technology Plan Project,No.23ywb146 and Start-up Fund of Guizhou Medical University,No.J2021032
主 题：Inflammation Primary liver cancer Hepatocellular carcinoma Nonalcoholic fatty liver disease Hepatitis virus
摘 要：Primary liver cancer is a severe and complex disease,leading to 800000 global deaths *** evidence suggests that inflammation is one of the critical factors in the development of hepatocellular carcinoma(HCC).Patients with viral hepatitis,alcoholic hepatitis,and steatohepatitis symptoms are at higher risk of developing ***,not all inflammatory factors have a pathogenic function in HCC *** current study describes the process and mechanism of hepatitis development and its progression to HCC,particularly focusing on viral hepatitis,alcoholic hepatitis,and ***,the roles of some essential inflammatory cytokines in HCC progression are described in addition to a summary of future research directions.
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