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Chinese Physics B 2022年第6期31卷 580-588页

作者： Ning Wei ai-qiang shi Zhi-Hui Li Bing-Xian Ou Si-Han Zhao Jun-Hua Zhao Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology Jiangnan UniversityWuxi 214122China China Aerodynamics Research and Development Center Mianyang 621000China National Laboratory for Computational Fluid Dynamics Beijing 100191China National Graphene Products Quality Supervision and Inspection Center Special Equipment Safety Supervision Inspection Institute of Jiangsu ProvinceWuxi 214174China

The plastic deformation properties of cylindrical pre-void aluminum-magnesium(Al-Mg)alloy under uniaxial tension are explored using molecular dynamics simulations with embedded atom method(EAM)*** factors of Mg content,void size,and temperature are *** results show that the void fraction decreases with increasing Mg in the plastic deformation,and it is almost independent of Mg content when Mg is beyond 5%.Both Mg contents and stacking faults around the void affect the void *** phenomena are explained by the dislocation density of the sample and stacking faults distribution around the *** variation trends of yield stress caused by void size are in good agreement with the Lubarda ***,temperature effects are explored,the yield stress and Young’s modulus obviously decrease with *** results may enrich and facilitate the understanding of the plastic mechanism of Al-Mg with defects or other alloys.

关键词： Al-Mg alloys molecular dynamics nanovoid plastic deformation

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： shi-Yan Sun Lingyun Nie Jing Zhang Xue Fang Hongmei Luo Chuanhai Fu Zhiyi Wei ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

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新疆萨热克铜矿床矿石组构特征与成因

矿物学报 2017年第5期37卷 638-645页

作者：李世恒刘正桃黄行凯艾世强赵路通昆明理工大学国土资源工程学院云南昆明650000 北京矿产地质研究院北京100012

萨热克铜矿位于新疆乌恰县境内,是我国目前最大规模的砂砾岩容矿的层状铜矿床,主要赋矿地层为上侏罗统库孜贡苏组(J3k)的砾岩及砂砾岩,具有"辉铜矿-斑铜矿-黄铜矿-黄铁矿"的矿化分带,发育完整的杂色地层组合,与典型砂岩铜矿特征相似。... 详细信息

萨热克铜矿位于新疆乌恰县境内,是我国目前最大规模的砂砾岩容矿的层状铜矿床,主要赋矿地层为上侏罗统库孜贡苏组(J3k)的砾岩及砂砾岩,具有"辉铜矿-斑铜矿-黄铜矿-黄铁矿"的矿化分带,发育完整的杂色地层组合,与典型砂岩铜矿特征相似。通过系统的野外和镜下观察,总结了该矿床矿石的组构特征,结合矿物组合、结构构造、交插关系等特征,将该矿床划分为3个成矿期次,分别为沉积成矿期、热液改造期及表生富集期,初步认为该矿床为与盆地卤水活动有关的低温热液矿床。

关键词：萨热克铜矿砂岩型铜矿矿物组成结构构造矿床成因

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

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Science China Chemistry 2025年第1期 174-180页

作者： Fan-Xiao Meng Xing-Yu Wang Ka Lu Ju-Song Yang Fu-Min Zhang ai-Jun Ma Bao Du Yong-qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

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新疆萨热克铜矿辉绿岩地球化学特征与动力学意义

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矿物学报 2017年第5期37卷 646-652页

作者：黄行凯艾世强崔乐乐李世恒赵路通赵志丹北京矿产地质研究院北京100012 中国地质大学(北京)地球科学与资源学院北京100083 昆明理工大学国土资源工程学院云南昆明650093

萨热克铜矿的南矿带发育了大量的辉绿岩脉,本文针对地表和钻孔中采集的辉绿岩样品开展了岩石地球化学研究。结果显示,岩石w(Si O2)在40.36%~44.78%之间,w(TFe2O3)(全铁)和w(Ti O2)变化范围分别为7.19%~10.67%和2.28%~2.73%,呈现高钛、... 详细信息

萨热克铜矿的南矿带发育了大量的辉绿岩脉,本文针对地表和钻孔中采集的辉绿岩样品开展了岩石地球化学研究。结果显示,岩石w(Si O2)在40.36%~44.78%之间,w(TFe2O3)(全铁)和w(Ti O2)变化范围分别为7.19%~10.67%和2.28%~2.73%,呈现高钛、富碱和贫硅的演化趋势,属于高钛系列辉长(绿)岩类;稀土和微量元素具有与OIB相似的特征。萨热克辉绿岩岩石地球化学特征与托云盆地玄武岩极其相似,二者应为同源产物,形成于板内拉伸构造环境,可能与岩石圈拆沉作用有关,受控于印度-亚洲大陆碰撞的远程效应。

关键词：西南天山萨热克铜矿辉绿岩地球化学特征动力学意义

Clinical features and treatment of near-work-related acquired esotropia

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International Journal of Ophthalmology(English edition) 2022年第8期15卷 1338-1343页

作者： Rui-Lin Guo Li-Kun ai shi-qiang Zhao Department of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical UniversityBeijing 100730China

aiM:To investigate the characteristics of near-workrelated esotropia and the clinical efficacy of botulinum toxin type A(BTXA)injection therapy on ***:A total of 107 patients aged 15-57y with near-work-related esotropia were taken as the BTXA-treated group,and 30 other peers without near-work-related esotropia were included in the control *** participants were refractive corrected to analyse the clinical characteristics of near-work-related *** subjects were examined including Worth4 spot examination,stereoscopic vision,strabismus angle,accommodative convergence to accommodation ratio(AC/A),far and near positive and negative convergence,positive and negative fusion range,positive and negative relative *** efficacy was evaluated at a period of 10mo ***:The distant and near stereopsis were found in 84.9%and 77.5%of patients in the BTXA-treated group,*** the control group,all patients had distant and near *** incidence of taking off one's glasses to see close objects was significantly higher in the BTXA-treated group than in the control group(P<0.05).The BTXA-treated group showed a smaller range of infusion(9.84±5.72)°than the control group(22.04±8.71)°(P<0.05).The near esotropia angle of the BTXA-treated group(17.08±11.98)△was significantly smaller than the distant esotropia angle(19.07±11.68)△(P<0.05).Ten months after injection,the diplopia and esotropia of most patients underwent improvements after treatment(P<0.05).CONCLUSION:This study reveals that the accommodation function and the habit of near work without wearing spectacles are associated with near-work-related esotropia,while the length of time for near work and the onset time are independent of near-work-related ***,BTXA injection therapy plays a vital role in relieving diplopia and restoring eye position.

关键词： esotropia near-work botulinum toxin accommodation electromyography

Protective effect of high-oleic acid peanut oil and extra-virgin olive oil in rats with diet-induced metabolic syndrome by regulating branched-chain amino acids metabolism

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Journal of Integrative Agriculture 2022年第3期21卷 878-891页

作者： ZHAO Zhi-hao shi ai-min GUO Rui LIU Hong-zhi HU Hui WANG qiang Institute of Food Science and Technology Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-Products ProcessingMinistry of Agriculture and Rural AffairsBeijing 100193P.R.China Collaborative Innovation Center for Modern Grain Circulation and Safety College of Food Science and EngineeringNanjing University of Finance and EconomicsNanjing 210023P.R.China

High-oleic acid peanut oil(HOPO)and extra-virgin olive oil(EVOO)have been reported previously to have an attenuating effect on metabolic syndrome(MS).This study aimed to evaluate the metabolic effect of HOPO and EVOO supplementation in attenuating MS and the role of gut microbiota in regulating the metabolic ***-Dawley rats were continuously fed with a normal diet,high-fructose and high-fat(HFHF)diet,HFHF diet containing HOPO,or a HFHF diet containing EVOO for 12 *** metabolomics profiles of feces and serum samples were compared using untargeted metabolomics based on UPLC-Q/*** Least Squares Discriminant Analysis(PLS-DA)was used to identify the potential fecal and serum biomarkers from different *** between gut microbiota and biomarkers was assessed,and pathway analysis of serum biomarkers was *** in metabolic patterns in feces and serum were observed among different *** were 8 and 12 potential biomarkers in feces and 15 and 6 potential biomarkers in serum of HOPO group and EVOO group,respectively,suggesting that HOPO and EVOO supplementation mainly altered amino acids,peptides,and their analogs in feces and *** branched-chain amino acids(BCAAs)biosynthesis pathway was identified as a major pathway regulated by HOPO or *** study suggests that HOPO and EVOO supplementation ameliorate diet-induced MS,mainly via modulation of the BCAAs biosynthesis pathway.

关键词： metabolic syndrome high-oleic acid peanut oil extra-virgin olive oil metabolomics UPLC-Q/TOF-MS

Simulation and Prediction of Alkalinity in Sintering Process Based on Grey Least Squares Support Vector Machine

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Journal of Iron and Steel Research International 2009年第5期16卷 1-6页

作者： SONG qiang WANG ai-min Mechanical Engineering Department Anyang Institute of Technology Anyang 455000 Henan China Computer and Information Engineering College Anyang Normal University Anyang 455000 Henan China

The prediction of the alkalinity is difficult during the sintering process. Whether or not the level of the alkalinity of sintering process is successful is directly related to the quality of sinter. There is no very good method for predicting the alkalinity by now owing to the high complexity, high nonlinearity, strong coupling, high time delay, and etc. Therefore, a new technique, the grey squares support machine, was introduced. The grey support vector machine model of the alkalinity enabled the development of new equation and algorithm to predict the alkalinity. During modelling, the fluctuation of data sequence was weakened by the grey theory and the support vector machine was capable of processing nonlinear adaptable information, and the grey support vector machine has a combination of those advantages. The results revealed that the alkalinity of sinter could be accurately predicted using this model by reference to small sample and information. The experimental results showed that the grey support vector machine model was effective and practical owing to the advantages of high precision, less samples required, and simple calculation.

关键词： alkalinity sinter grey least squares support vector machine prediction sintering process grey model

The behavior of deep convective clouds over the warm pool and connection to the Walker circulation

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Science China Earth Sciences 2018年第11期61卷 1605-1621页

作者： Wenjing shi Ziniu XIAO Yufei ai Beijing Institute of Applied Meteorology Beijing 100029 China Beijing Goldwind Science & Creation Windpower Equipment Co. Ltd. Xinjiang Goldwind Science & Technology Co. Ltd. Beijing 100176 China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG) Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Laboratory for Climate and Ocean-Atmosphere Studies Department of Atmospheric and Oceanic Sciences School of Physics Peking University Beijing 100871 China

As the deep convective clouds(DCCs) over the western Pacific and Indian Ocean warm pool may play different roles in the climate system, variations in DCC properties over these two sectors are investigated and compared. The DCC intensity and area varies more significantly in the Indian Ocean than the western Pacific sector, while the DCC frequency is comparable in both sectors at the seasonal scale. Although the Indian Ocean sector is strongly dominated by the seasonal evolution, the interannual variations in the two sectors are comparable for all three DCC properties(frequency, intensity, and area). Besides,Walker circulation is closely correlated with the interannual variability of DCCs in both sectors. The Walker circulation strengthens(weakens) as the DCCs shift eastward(westward) over the Indian Ocean sector and westward(eastward) over the western Pacific sector. When more or stronger DCCs occur over the Indian Ocean sector(western Pacific sector), the Walker circulation becomes stronger(weaker) and shifts westward(eastward). Interestingly, the response of the Walker circulation to DCC variability over the warm pool is asymmetry. The asymmetry response of the Walker circulation to the negative and positive DCC anomaly may be related to the non-linearity internal variability of the atmosphere. DCCs over the Indian Ocean sector have a much weaker nonlinear correlation with the Walker circulation than DCCs over the western Pacific sector.

关键词： Satellite data Deep convective clouds Asymmetry response Walker circulation

POINCARE-LIGHTHILL-KUO METHOD AND SYMBOLIC COMPUTATION

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Applied Mathematics and Mechanics(English Edition) 2001年第3期22卷 261-269页

作者： Dai shi-qiang(戴世强) Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 P R China

This paper elucidates the effectiveness of combining the Poincare-Lighthill-Kuo method (PLK method, for short) and symbolic computation. Firstly, the idea and history of the PLK method are briefly introduced. Then, the difficulty of intermediate expression swell, often encountered in symbolic computation, is outlined. For overcoming the difficulty, a semi-inverse algorithm was proposed by the author, with which the lengthy ports of intermediate expressions are first frozen in the form of symbols till the Fnal stage of seeking perturbation solutions. Tn discuss the applications of the above algorithm, the related work of the author and his research group on nonlinear oscillations and waves is concisely reviewed. The computer-extended perturbation solution of the Duffing equation shows that the asymptotic solution obtained with the PLK method possesses the convergence radius of 1 and thus the range of validity of the solution is considerably enlarged. The studies on internal solitary waves in stratified fluid and on the head-on collision between two solitary waves in a hyperelastic rod indicate that by means of the presented methods, very complicated manipulation, unconceivable in hand calculation, can be conducted and thus result in higher-order evolution equations and asymptotic solutions. The examples illustrate that the algorithm helps to realize the symbolic computation on micro-commputers. Finally, it is concluded that,vith the aid of symbolic computation, the vitality of the PLK method is greatly. Strengthened and at least for the solutions to conservative systems of oscillations and waves, it is a powerful tool.

关键词： PLK method perturbation methods symbolic computation intermediate expression swell semi-inverse algorithm