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Cartilage tympanoplasty in the treatment of adhesive otitis media with and without Eustachian tube balloon dilatation

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Journal of Otology 2022年第4期17卷 226-231页

作者： ahmed abdel rahman abdel aziz ahmed Mahmoud Youssef Mostafa Mohamed Mostafa Mostafa talaat Khaled Mohamed abdelzaher ahmed Adel Sadeq Department of Otorhinolaryngology Faculty of MedicineEl MiniaEgypt Radiology Department Faculty of MedicineEl MiniaEgypt

Purpose:To compare cartilage tympanoplasty(CT)combined with eustachian tube balloon dilatation(ETBD)and cartilage tympanoplasty alone as a surgical treatment modality for adhesive otitis media(AdOM)in terms of graft healing,audiological outcomes,and impact on life style,using Chronic Otitis Media Outcome Test 15(COMOT-15).Methods:50 patients with AdOM were randomly classified into 2 groups:25 patients for cartilage tympanoplasty only(CT group)and 25 patients for cartilage tympanoplasty combined with eustachian tube balloon dilatation(CT t ETBD group).Clinical outcomes in both groups were compared at 3 and 6 months of follow up.Results:There was no significant difference in graft healing between the two groups.Postoperative COMOT-15 scores significantly decreased in both groups with a significant difference between the groups with regard to the decrease in COMOT-15 scores at 3 and 6 months of follow-up(P<0.05).Hearing improvement was achieved,as the mean preoperative ABG was 26.5±5.4 and 27.1±4.6 dB,and the mean postoperative ABG at 6 months was 19.4±4.4 and 14.6±3.9 dB in the CT and the CT t ETBD groups,respectively.The difference in the magnitude of ABG reduction in the two groups was significant at 3 and 6 months of postoperative follow-up(P<0.05)in favour of the CT t ETBD group.Conclusion:ETBD can increase the success rate of cartilage tympanoplasty in patients with AdOM by enhancing the audiological outcome and quality of life.

关键词： balloon healing otitis

Oncologic outcomes with and without amniotic membranes in robotic-assisted radical prostatectomy:A propensity score matched analysis

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Asian Journal of Urology 2024年第1期11卷 19-25页

作者： Jonathan Noël Daniel Stirt Marcio Covas Moschovas Sunil Reddy abdel rahman Jaber Marco Sandri Seetharam Bhat Travis Rogers Subuhee ahmed Anya Mascarenhas Ela Patel Vipul Patel Advent Health Global Robotics Institute CelebrationFLUSA University of Central Florida College of Medicine OrlandoFLUSA Big and Open Data Innovation Laboratory University of BresciaItaly SUNY Upstate Medical University SyracuseNYUSA Kansas City University College of Medicine Kansas CityMOUSA Harvard University CambridgeMAUSA

Objective:Placement of human placenta derived grafts during robotic-assisted radical prostatectomy(RARP)hastens the return of continence and potency.The long-term impact on the oncologic outcomes remains to be investigated.Our objective was to determine the oncologic outcomes of patients with dehydrated human amnion chorion membrane(dHACM)at RARP compared to a matched cohort.Methods:In a referral centre,from August 2013 to October 2019,599 patients used dHACM in bilateral nerve-sparing RARP.We excluded patients with less than 12 months follow-up,simple prostatectomy,and unilateral nerve-sparing.Patients with dHACM(amnio group)were 529,and were propensity score matched 1:1 to 2465 patients without dHACM(non-amnio group)and a minimum follow-up of 36 months.At the time of RARP,dHACM was placed around the neurovascular bundle in the amnio group.Continuous and categorical variables in matched groups was tested by two-sample Kolmogorov-Smirnov test and Fisher's exact test respectively.Outcomes measured were biochemical recurrence(BCR),adjuvant and salvage therapy rates.Results:Propensity score matching resulted in two groups of 444 patients.Cumulative incidence functions for BCR did not show a difference between the groups(p=0.3).Patients in the non-amnio group required salvage therapy more frequently than the amnio group,particularly after partial nerve-sparing RARP(6.3%vs.2.3%,p=0.001).Limitations are the absence of prospective randomization.Conclusion:The data suggest that using dHACM does not have a negative impact on BCR in patients.Outcomes of cancer specific and overall survival will require follow-up study to increase our understanding of these grafts’impact on prostate cancer biology.

关键词： Prostatectomy Prostatecancer Robotic Oncology Outcome Allograft Biomaterial Dehydrated human amnionchorion membrane

Rescue effects of aqueous seed extracts of Foeniculum vulgare and Carum carvi against cadmium-induced hepatic, renal and gonadal damage in female albino rats

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Asian Pacific Journal of Tropical Medicine 2017年第12期10卷 1123-1133页

作者： ahmed abdel-Wahab abdel-Razik Hashem abdel-Razik Rabie Lotfy abdel aziz Physiology Department Faculty of Veterinary MedicineMinia University61519 El-MiniaEgypt Histology Department Faculty of Veterinary MedicineBeni-Suef University62512 Beni-SuefEgypt Department of Theriogenology Faculty of Veterinary MedicineBeni-Suef University62512 Beni-SuefEgypt

Objective: To investigate the protective effects of aqueous seed extracts of fennel"Foeniculum vulgare"(FVE) and caraway "Carum carvi"(CCE) on liver, kidney and reproductive organs in female rats against cadmium chloride(CC) intoxication.Methods: A total of 36 adult female rats were divided into six groups, six in each group.Control group(fed normal diet), CC-treated group(50 mg CC/kg diet), CCE-treated group(150 mg CCE/kg diet), CCE + CC group, FVE(150 mg/kg diet) and FVE + CC. One month later, all rats were sacrificed and all samples were collected at proestrus phase.Results: The toxic effects of CC were confirmed biochemically by significant increase of serum concentration of liver enzymes(P < 0.05), and creatinine(P < 0.001). Moreover,CC increased significantly the serum level of malondialdehyde(MDA) and decreased the total antioxidant capacity(TAC)(P < 0.001). In addition, serum concentrations of estrogen, progesterone, follicle-stimulating hormone(FSH) and luteinizing hormone(LH)were significantly decreased(P < 0.01). Histopathologically, CC-treated group revealed marked pathological changes in renal, hepatic, ovarian and uterine tissues. All toxic findings observed in liver and kidney with CC treatment were found to be ameliorated markedly after co-treatments with FVE or CCE. Furthermore, co-treatment of FVE with CC improved significantly all studied reproductive parameters(P < 0.01).Conclusions: Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication.

关键词： Cadmium Carum carvi Foeniculum vulgare Liver Kidney Fertility

Electromagnetic effects on the orbital motion of a charged spacecraft

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Research in Astronomy and Astrophysics 2014年第5期14卷 589-600页

作者： Yehia ahmed abdel-aziz Khalil Ibrahim Khalil National Research Institute of Astronomy and Geophysics (NRIAG) Helwan Cairo 11721Egypt Department of Mathematics Hail University Hail 2440 Kingdom of Saudi Arabia

This paper deals with the effects of electromagnetic forces on the orbital motion of a spacecraft. The electrostatic charge which a spacecraft generates on its surface in the Earth＇s magnetic field will be subject to a perturbative Lorentz force. A model incorporating all Lorentz forces as a function of orbital elements has been developed on the basis of magnetic and electric fields. This Lorentz force can be used to modify or perturb the spacecraft＇s orbits. Lagrange＇s planetary equations in the Gauss variational form are derived using the Lorentz force as a perturbation to a Keplerian orbit. Our approach incorporates orbital inclination and the true anomaly. The numer- ical results of Lagrange＇s planetary equations for some operational satellites show that the perturbation in the orbital elements of the spacecraft is a second order perturba- tion for a certain value of charge. The effect of the Lorentz force due to its magnetic component is three times that of the Lorentz force due to its electric component. In addition, the numerical results confirm that the strong effects are due to the Lorentz force in a polar orbit, which is consistent with realistic physical phenomena that occur in polar orbits. The results confirm that the magnitude of the Lorentz force depends on the amount of charge. This means that we can use artificial charging to create a force to control the attitude and orbital motion of a spacecraft.

关键词： space vehicles -- atmospheric effects -- celestial mechanics -- kine-matics and dynamics

Antifouling evaluation of extracts from Red Sea soft corals against primary biofilm and biofouling

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 991-997页

作者： Yosry abdel aziz Soliman ahmed Mohammed Brahim ahmed Hussein Moustafa Mohamed abdel Fattah Hamed Marine Chemistry Lab. Marine Environment DivisionNational Institute of Oceanography and FisheriesSuezEgypt Department of Chemistry Faculty of ScienceZagazig UniversityZagazigEgypt

Objectives: To evaluate antifouling property of extracts from Red Sea soft corals against primary biofilm and biofouling.Methods: Seven species of soft corals Sarcophyton glaucum(a), Sinularia compressa,Sinularia cruciata(a), Heteroxenia fuscescens(a), Sarcophyton glaucum(b), Heteroxenia fuscescens(b) and Sinularia cruciata(b) were chosen to test their extracts as antibacterial and antifouling agents in Eastern Harbour of Alexandria, Mediterranean Sea.Bioactive compounds of soft corals were extracted by using methanol and concentrated under vacuum. The residues of extracts were mixed in formulation of inert paint which consisted of rosin, chlorinated rubber and ferrous oxide against micro and macro fouling organisms. The formulated paints were then applied on PVC panels twice by brush,hanged in a steel frame and immersed in Eastern Harbour of Alexandria Mediterranean Sea followed by visual inspection and photographic recordings.Results: After 185 days of immersion in seawater, the antifouling results agreed with the antibacterial results where extracts of Sinularia compressa and Heteroxenia fuscescens(b) gave the best activity against marine fouling tubeworms and barnacles. The inhibition activity was correlated with the major functional groups(hydroxyl, amino, carbonyl,aliphatic(fatty acids), C]C of alkene or aromatic rings and CeC l of aryl halides) of the extracts.Conclusions: The strong antifouling activity makes them promising candidates for new antifouling additives. After the screening and application of natural organic compounds from soft corals, marine organisms show activity against micro and macro fouling organisms.

关键词： Antibacterial Antifouling Paints Seawater Marine Organisms

Improvement of Selected Morphological, Physiological, and Biochemical Parameters of Banana (Musa acuminata L.) Using Potassium Silicate under Drought Stress Condition Grown in vitro

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Phyton-International Journal of Experimental Botany 2023年第4期92卷 1019-1036页

作者： Hosny abdel aziz Mohamed Sharaf Magdy Omar ahmed Abou El-Yazied Nada Ibrahim AlJwaizea Shaimaa Ismail Mohamed M.A.Omar Khadiga Alharbi Amr Elkelish Moataz Tawfik Department of Horticulture Faculty of AgricultureAl-Azhar UniversityCairo11651Egypt Department of Biochemistry Faculty of AgricultureAl-Azhar UniversityCairo11651Egypt Department of Biochemistry and Molecular Biology College of Marine Life SciencesOcean University of ChinaQingdao266003China Department of Agricultural Botany Faculty of AgricultureAl-Azhar UniversityNasr CityCairo11751Egypt Department of Horticulture Faculty of AgricultureAin Shams UniversityCairo11566Egypt Department of Biology College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia Department of Biochemistry Faculty of AgricultureAin Shams UniversityCairo11566Egypt Biology Department College of ScienceImam Mohammad ibn Saud Islamic University(IMSIU)Riyadh11623Saudi Arabia Botany Department Faculty of ScienceSuez Canal UniversityIsmailia41522Egypt Botany Department Faculty of SciencePort Said UniversityPort Said42511Egypt

Drought stress has become more common in recent years as a result of climate change impacts on the production of banana crops and other fruit trees.The growth and productivity of Musa spp are severely impacted by the gradual degradation of water resources and the erratic distribution pattern of annual precipitation amount.The aim of the work includes increased drought tolerance in light of water scarcity in the world as a result of the bananas’being gluttonous for water needs.This investigation was carried out from 2019 to 2020 to study the effect of potassium silicate on morphological growth and biochemical parameters of Musa acuminata L under drought stress by PEG.As a result,drought stress reduced the morphological characteristics such as shoots number,shoot length,roots number,and survival percentage and biochemical characteristics such as chlorophyll a,b,carotenoids,stomatal status,and RWC.While proline content increased in the leaf of M.acuminata L.Media complemented with K2SiO3(2 to 6 mM)either individually or in combination with PEG led to an improvement in all morphological and biochemical characteristics.The activities of CAT,POD,and PPO enzymes increased significantly compared to control.Furthermore,the lowest PPO,CAT,and POD activity were achieved.Additionally,K2SiO3 treatments under drought stress successfully enhanced the leaf stomatal behavior.Our results suggest that K2SiO3 can help to maintain plant integrity in the tested cultivar under drought stress.

关键词： Musa acuminata L potassium silicate photosynthetic pigments stomata enzymatic activity

Types of trematodes infecting freshwater snails found in irrigation canals in the East Nile locality,Khartoum,Sudan

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Infectious Diseases of Poverty 2016年第1期5卷 139-148页

作者： Nidal A.I.Mohammed Henry Madsen abdel aziz A.R.M.ahmed Department of Zoology Khartoum College of Medical SciencesKhartoumSudan Parasitology and Aquatic Diseases Department of Veterinary Disease BiologyFaculty of Health and Medical SciencesUniversity of CopenhagenFrederiksbergDenmark Education Expert Company RiyadhKingdom of Saudi Arabia

Background:The planorbid freshwater snails of the two genera,Biomphalaria and Bulinus-have been vigorously studied due to the role they play as intermediate hosts of schistosomiasis.In Sudan specifically,most studies have focused on the chemical and ecological control of the two genera,but few studies have looked at their biological control.This study explored the coexistence of other species of freshwater snails and the two genera along with their trematode infections in relation to a number of environmental factors in the East Nile locality,Khartoum state,Sudan.Methods:Freshwater snails from irrigation canals(abueshreens)were sampled monthly from January 2004 to December 2005.The snails were examined for trematode infections by cercarial emergence immediately after collection and then weekly for an additional four weeks to allow for the maturation of prepatent infections.Vegetation cover in the study sites as well as the physicochemical characteristics of the water,including temperature,were also recorded.Results:A total of 10,493 snails,representing seven species,were collected.The most abundant species was Biomphalaria pfeifferi,representing 48.6%of the sample.Overall,14.1%of the snails were found to be shedding some type of cercariae.Five species were found to have infections;among these the Bulinus truncatus species was found to be the most heavily infected,with an overall prevalence of 46.2%.Double infections were recorded in only two B.truncatus snails and one Cleopatra bulimoides snail.Twenty different morphotypes of cercariae were recorded,seven of which appeared not to conform to previously described cercariae from Africa.Xiphidiocercariae type 1 was the most common type of cercariae recovered,accounting for 44.3% of all infections.The density of snails tended to be lower during the summer months than the winter months,except for M.tuberculata snails,which were not affected by seasonal changes.Conclusion:The findings of this study indicate that besides schistosomes,other larval trematodes are found,and

关键词： Freshwater snails Trematode cercariae Biomphalaria Bulinus East Nile locality Khartoum Sudan

Assessment of heme oxygenase-1 （HO-1） activity in the cavernous tissues of sildenafil citrate-treated rats

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Asian Journal of Andrology 2007年第3期9卷 377-381页

作者： M. Talaat abdel aziz M. Farid Al-Asmar Taymour Mostafa Hazem Atta Laila Rashed Dina Sabry Shedeed Ashour ahmed T. abdel aziz Molecular Biology Unit Medical Biochemistry Department Faculty of Medicine Cairo University Cairo 11553 Egypt Medical Biochemistry Department Faculty of Medicine Ain Shams University Cairo Egypt Andrology Department Faculty of Medicine Cairo University Cairo 11553 Egypt

Aim： To assess heine oxygenase-1 （HO-1） activity in the cavemous tissue of sildenafil citrate-treated rats. Methods： One hundred and ninety-two Sprague-Dawley male rats, divided into four equal groups, were investigated. Group 1, the control group, received regular animal chow; group 2 received sildenafil citrate by intragastric tube; group 3 received sildenafil and HO inhibitor （zinc protoporphyrin, ZnPP）; and group 4 received sildenafil and nitric oxide synthase （NOS） inhibitor L-nitroarginine methyl ester （L-NAME）. Twelve rats from each group were killed after 0.5 h, 1 h, 2 h and 3 h of drug administration. Then HO-1 activity, cGMP levels and NOS enzymatic activity in the cavernous tissues were estimated. Results： In cavemous tissue, HO-1 activity, NOS enzymatic activity and cGMP concentration increased significantly in sildenafil-treated rats compared to other groups throughout the experiment. Rats receiving either HO or NOS inhibitors showed a significant decrease in these parameters. HO- 1 cavemous tissue activity and NOS enzymatic activity demonstrated a positive significant correlation with cGMP levels （r = 0.646, r = 0.612 respectively; P 〈 0.001）. Conclusion： The actions of PDE5 inhibitor sildenafil citrate in the cavernous tissue are partly mediated through the interdependent relationship between both HO-1 and NOS activities.

关键词： erectile dysfunction heme oxygenase sildenafil citrate nitric oxide synthase carbon monoxide

An efficient oxidation of benzylic and alicylic compounds with water-soluble copper catalysts in t-butyl hydroperoxide at room temperature

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Chinese Chemical Letters 2011年第6期22卷 691-693页

作者： Ateeq rahman S.M.Al Zahrani abdel aziz Nait Ajjou College of Engineering Department of Chemical Engineering King Saud University Department of Chemistry and Biochemistry University of Moncton

水可溶的催化系统包括 CuCl2 和 2,2-biquinoline-4,4-dicarboxylic 酸 dipotassium 盐(BQC ) 是为 benzylic 和脂环的混合物的选择氧化的高度有效的器官的金属性的催化剂到相应酉同类，前：indan 到 indanone，乙醇苯到 acetophenone。

关键词：选择性氧化化合物铜催化剂水溶性有机金属催化剂室温苄基丁基