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Cancer Pathogenesis and Therapy 2024年第2期2卷 74-80页

作者： Hanna Maroof Louise Paramore ahmed ali Department of Urology Frimley Park HospitalPortsmouth RdFrimleyCamberley GU167UJUnited Kingdom

Bladder cancer encapsulates a wide spectrum of disease severities,with non-muscle invasive bladder cancer(NMIBC)representing an entirely different entity from muscle-invasive *** Calmette-Guerin(BCG)is one of the most successful intravesical treatment methods for patients ***,a considerable pro-portion of patients fail to respond to BCG *** the propensity for recurrence in patients with high-risk bladder cancer,these patients present with surgical *** is currently no gold standard for salvage treatment post-BCG failure or unified definition as to what that *** this review,we discuss the mechanisms of action and pathophysiology of BCG,potential theories behind BCG failure,and the scope of novel treatments forthis surgical conundrum.

关键词： Cystectomy Hyperthermia Induced Immunotherapy Mycobacterium bovis Non-muscle-invasive bladder cancer

Single nucleotide polymorphism within chromosome 8q24 is associated with prostate cancer development in Saudi Arabia

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Asian Journal of Urology 2024年第1期11卷 26-32页

作者： Awad Elsid Osman Sahar Alharbi Atif ali ahmed Asim ali Elbagir Pathology and Clinical Laboratory Management Department(PCLM) King Fahad Medical CityRiyadhSaudi Arabia Department of Pathology and Laboratory Medicine University of Missouri at Children's Mercy HospitalKansas CityMOUSA

Objective: Genome-wide association studies have demonstrated that single nucleotide polymorphisms (SNPs) are important risk factors for the development of prostate cancer (PCa). Preliminary studies have suggested that the incidence of PCa in Saudi males is low but is probably familial or genetically ***: To identify any possible association of SNP with PCa development in Saudi patients, we investigated a group of SNPs in Saudi PCa patients (n=85) and compared the outcomes to healthy normal controls (n=115) and nodular hyperplasia patients (n=120). DNA was extracted from paraffin-embedded formalin fixed tissue or whole blood from both patients’ groups and healthy control group. A total of thirteen SNPs were genotyped using TaqMan® minor groove binder polymerase chain reaction ***: The rs16901979A, s629242T and rs1447295A alleles were found at significantly higher frequency in PCa patients than controls (p< 0.05). The rs16901979 CA genotype was found at significantly greater frequency in PCa patients than in healthy controls (43% vs. 14%, odds ratio=4.6, p=0.0001) and benign hyperplasia group (43% vs. 25%, odds ratio=2.2, p=0.009).Conclusion: Our study has highlighted the association of rs16901979 SNP with PCa in Saudi males. Such findings have important implications in the PCa diagnosis and in screening unaffected family members of Saudi patients.

关键词： Prostatecancer Saudi Singlenucleotide polymorphism Allele

A gated recurrent unit model to predict Poisson’s ratio using deep learning

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 123-135页

作者： Fahd Saeed Alakbari Mysara Eissa Mohyaldinn Mohammed Abdalla Ayoub Ibnelwaleed A.Hussein ali Samer Muhsan Syahrir Ridha Abdullah Abduljabbar salih Petroleum Engineering Department Universiti Teknologi PETRONAS32610Bandar Seri IskandarPerakMalaysia Institute of Hydrocarbon Recovery Universiti Teknologi PETRONAS32610Bandar Seri IskandarPerakMalaysia Gas Processing Center College of EngineeringQatar UniversityP.O.Box 2713DohaQatar Department of Chemical Engineering College of EngineeringQatar UniversityP.O.Box 2713DohaQatar Mechanical Engineering Department Universiti Teknologi PETRONAS32610Bandar Seri IskandarPerakMalaysia

Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand *** models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical *** this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error *** GRU model showed the proper trends,and the model data ranges were wider than previous *** GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other *** GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,*** group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.

关键词： Static Poisson’s ratio Deep learning Gated recurrent unit(GRU) Sand control Trend analysis Geomechanical properties

Some of the Chemical and Physical Characteristics of the Graff River in Kut City, Iraq

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Open Journal of Modern Hydrology 2024年第1期14卷 56-67页

作者： salih Mahdi ali Imad Kazem ali Ministry of Education Wasit Education Directorate Wasit Governorate Iraq Department of Animal Production College of Agriculture Sumer University Al-Rifai Iraq

Some of the chemical and physical water qualities of the Graff River in the city of Kut were studied, and for two sites of the river, One was at the Crimea site, the other in the Jihad district, and for the period from October/2018 to March/2019, Seven variables of river water have been analyzed: temperature PH, electrical conductivity, TDS, turbidity, alkaline, and chloride. The results showed that most of the chemical and physical water properties of the river were in normal proportions and did not rise, except for the turbidity, which was at a very high level, and that the pH values were close to the basal side. The results of the statistical analysis revealed positive significant relationships between the pH and (chloride and TDS). On the other hand, between electrical conductivity and both previous variables as well. And a negative significant connection between temperature and alkaline.

关键词： Graff River Kut City Iraq Chemical Characteristics Physical Characteristics

AI-Driven Energy Optimization in UAV-Assisted Routing for Enhanced Wireless Sensor Networks Performance

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Computers, Materials & Continua 2024年第9期80卷 4085-4110页

作者： Syed Kamran Haider Abbas ahmed Noman Mujeeb Khan ali Nauman Sung Won Kim College of Internet of Things(IoT)Engineering Hohai UniversityChangzhou213001China Department of Electrical and Electronics Engineering Beaconhouse International CollegeIslamabad44000Pakistan School of Computer Science and Engineering Yeungnam UniversityGyeongsan38428Republic of Korea

In recent advancements within wireless sensor networks(WSN),the deployment of unmanned aerial vehicles(UAVs)has emerged as a groundbreaking strategy for enhancing routing efficiency and overall network *** research introduces a sophisticated framework,driven by computational intelligence,that merges clustering techniques with UAV mobility to refine routing strategies in *** proposed approach divides the sensor field into distinct sectors and implements a novel weighting system for the selection of cluster heads(CHs).This system is primarily aimed at reducing energy consumption through meticulously planned routing and path *** a greedy algorithm for inter-cluster dialogue,our framework orchestrates CHs into an efficient communication *** comparative analysis,the proposed model demonstrates a marked improvement over traditional methods such as the cluster chain mobile agent routing(CCMAR)and the energy-efficient cluster-based dynamic algorithms(ECCRA).Specifically,it showcases an impressive 15%increase in energy conservation and a 20%reduction in data transmission time,highlighting its advanced ***,this paper investigates the impact of various network parameters on the efficiency and robustness of the WSN,emphasizing the vital role of sophisticated computational strategies in optimizing network operations.

关键词： UAV trajectory clustering next-generation wireless sensor network(NGWSN) energy efficiency mobile sink

Secure and Reliable Routing in the Internet of Vehicles Network:AODV-RL with BHA Attack Defense

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 633-659页

作者： Nadeem ahmed Khalid Mohammadani ali Kashif Bashir Marwan Omar Angel Jones Fayaz Hassan School of Electronic Science Beijing University of Post and TelecommunicationBeijing100086China Department of Computer Science Huanggang Normal UniversityHuanggangChina Department of Computing and Mathematics Manchester Metropolitan UniversityManchesterUK Woxsen School of Business Woxsen UniversityHyderabad502345India Department of Computer Science and Mathematics Lebanese American UniversityBeirutLebanon Information Technology and Management Illinois Institute of TechnologyChicagoUSA College of Computing Capital Technology UniversityLaurelUSA

Wireless technology is transforming the future of transportation through the development of the Internet of Vehicles(IoV).However,intricate security challenges are intertwinedwith technological progress:Vehicular ad hoc Networks(VANETs),a core component of IoV,face security issues,particularly the Black Hole Attack(BHA).This malicious attack disrupts the seamless flow of data and threatens the network’s overall reliability;also,BHA strategically disrupts communication pathways by dropping data packets from legitimate nodes *** the importance of this challenge,we have introduced a new solution called ad hoc On-Demand Distance Vector-Reputation-based mechanism Local Outlier Factor(AODV-RL).The significance of AODVRL lies in its unique approach:it verifies and confirms the trustworthiness of network components,providing robust protection against *** additional safety layer is established by implementing the Local Outlier Factor(LOF),which detects and addresses abnormal network *** testing of our solution has revealed its remarkable ability to enhance communication in ***,Our experimental results achieve message delivery ratios of up to 94.25%andminimal packet loss ratios of just 0.297%.Based on our experimental results,the proposedmechanismsignificantly improves VANET communication reliability and *** results promise a more secure and dependable future for IoV,capable of transforming transportation safety and efficiency.

关键词： Black hole attack IoV vehicular ad hoc network AODV routing protocol

A Comprehensive Review on Charging Topologies and Power Electronic Converter Solutions for Electric Vehicles

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 675-694页

作者： Abdelfatah ali Hossam H.H.Mousa Mostafa F.Shaaban Maher A.Azzouz ahmed S.A.Awad the Department of Electrical Engineering American University of Sharjah26666 SharjahUnited Arab Emirates the Department of Electrical Engineering South Valley University83523 QenaEgypt the Department of Electrical and Computer Engineering University of WindsorWindsorON N9B 3P4 Canada Electrical Engineering Department Qatar UniversityDoha 2713Qatar Department of Electrical and Computer Engineering Sultan Qaboos UniversityMuscat123Oman

Electric vehicles(EVs)are becoming more popular worldwide due to environmental concerns,fuel security,and price *** performance of EVs relies on the energy stored in their batteries,which can be charged using either AC(slow)or DC(fast)***,EVs can also be used as mobile power storage devices using vehicle-to-grid(V2G)*** electronic converters(PECs)have a constructive role in EV applications,both in charging EVs and in ***,this paper comprehensively investigates the state of the art of EV charging topologies and PEC solutions for EV *** examines PECs from the point of view of their classifications,configurations,control approaches,and future research prospects and their impacts on power *** can be classified into various topologies:DC-DC converters,AC-DC converters,DC-AC converters,and AC-AC *** address the limitations of traditional DC-DC converters such as switching losses,size,and high-electromagnetic interference(EMI),resonant converters and multiport converters are being used in high-voltage EV ***,power-train converters have been modified for high-efficiency and reliability in EV *** paper offers an overview of charging topologies,PECs,challenges with solutions,and future trends in the field of the EV charging station applications.

关键词： Charging station charging topology electric vehicle power electronic converter vehicle-to-grid

Rhizobium Inoculation and Micronutrient Addition Influence the Growth,Yield,Quality and Nutrient Uptake of Garden Peas(Pisum sativum L.)

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Phyton-International Journal of Experimental Botany 2024年第5期93卷 901-922页

作者： MdAbdul Quddus MdAtaur Rahman Razu ahmed Mohammad Eyakub ali Khokan Kumer Sarker MdAlamgir Siddiky Mohibur Rahman Lamya ahmed Alkeridis Samy Sayed ahmed Gaber Akbar Hossain Horticulture Research Centre Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Soil Science Division Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Irrigation and Water Management Division Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Regional Agricultural Research Station Bangladesh Agricultural Research InstituteCumilla3500Bangladesh Department of Biology College of SciencePrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Science and Technology University College‑RanyahTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Economic Entomology and Pesticides Faculty of AgricultureCairo UniversityGiza12613Egypt Department of Genetics Faculty of AgricultureCairo UniversityGiza12613Egypt Department of Biology College of ScienceTaif UniversityTaif21944Saudi Arabia Division of Soil Science Bangladesh Wheat and Maize Research InstituteDinajpur5200Bangladesh

Garden pea productivity and qualities are hampered in zinc(Zn),boron(B),and molybdenum(Mo)deficient ***,the combination of micronutrients(i.e.,Zn,B,and Mo)and rhizobium is necessary to increase the productivity and quality of garden peas,since this management for garden peas is neglected in ***,the present study was made to assess the effectiveness of rhizobium inoculant singly or in combination with the micronutrients(i.e.,Zn,B,and Mo)on growth,yield,nutrient uptake,and quality of garden *** were:T_(1)=Control,T_(2)=Rhizobium inoculation at 50 g/kg seed,T_(3)=T_(2)+Zn_(3)Mo1,T_(4)=T_(2)+B_(2)Mo1,T_(5)=T_(2)+Zn_(3)B_(2),T_(6)=T_(2)+Zn_(3)B_(2)Mo1 and T_(7)=Zn_(3)B_(2)*** treatments were arranged in a randomized complete block design and repeated all treatments in three *** application of 3 kg Zn,2 kg B,and 1 kg Mo ha^(−1)with inoculation of Rhizobium at 50 g kg^(−1)seed(T_(6))facilitated to increase of 44.8%in the green pod and 29.7%seed yield over *** same treatment contributed to attaining the maximum nodulation(25.3 plant^(−1)),Vitamin C(43.5 mg 100 g^(−1)),protein content(22.2%),and nutrient uptake as well as accumulation in garden *** all treatment combinations,treatment T_(6)was found superior to others based on microbial activities,soil fertility,and *** results of the study found that the application of 3 kg Zn,2 kg B,and 1 kg Mo ha^(−1)in combination with Rhizobium inoculation(50 g kg^(−1)seed)can improve the yield and quality of garden *** results of the study have the potential for the areas,where there is no use of Rhizobium inoculant or Zn,B,and Mo fertilizer for cultivation of garden pea.

关键词： Nodulation nutrient content Pisum sativum L. profitability rhizobium Zn B Mo

Standardization of meibomian gland dysfunction in an Egyptian population sample using a non-contact meibography technique

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 61-65页

作者： ahmed Mohamed Karara Zeinab El-Sanabary Mostafa ali El-Helw Tamer ahmed Macky Mohamad Amr Salah Eddin Abdelhakim Department of Ophthalmology Kasr Al-Ainy HospitalCairo UniversityCairo 11431Egypt

AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population ***:Observational,cross-sectional,analytic study,in which 104 Egyptian volunteers were *** upper lids were examined,using“Sirius CSO”*** eyelid was given a degree of meibomian gland loss(MGL),which was calculated by the software of the ***:Mean percentage MGL in right upper lid was of 30.9%±12.6%,and that of left upper lid was 32.6%±11.8%.Thirty-four volunteers(32.7%)had first-degree MGL in their right upper lid,and 67.3%had second-degree *** volunteer(1%)had zero-degree MGL in left upper lid,28(26.9%)had first-degree loss,and 75(72.1%)had second-degree *** of MGL in right upper eyelid was not related to age,but degree of MGL in left upper eyelid increased with *** was statistically significant difference between both genders for degree of MGL in right eye(P=0.036)and in left eye(P=0.027).CONCLUSION:Noncontact meibography is a useful non-invasive tool for diagnosing *** is diagnosed in 100%of apparently normal individuals;26.9%-32.7%of which have first-degree MGL,and 67.3%-72.1%have second-degree MGL.

关键词： Egyptian population meibomian gland dysfunction non-contact meibography standardization upper lid

Numerical Analysis of Bacterial Meningitis Stochastic Delayed Epidemic Model through Computational Methods

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 311-329页

作者： Umar Shafique Mohamed Mahyoub Al-Shamiri ali Raza Emad Fadhal Muhammad Rafiq Nauman ahmed Department of Mathematics National College of Business Administration and EconomicsLahore54660Pakistan Department of Mathematics Applied CollegeMahayl AssirKing Khalid UniversityAbha62529Saudi Arabia Department of Physical Sciences The University of ChenabGujrat50700Pakistan Department of Mathematics&Statistics College of ScienceKing Faisal UniversityP.O.Box 400Al-Ahsa31982Saudi Arabia Department of Computer Science and Mathematics Lebanese American UniversityBeirut1102-2801Lebanon Department of Mathematics Faculty of Science and TechnologyUniversity of Central PunjabLahore54000Pakistan Department of Mathematics and Statistics University of LahoreLahore54000Pakistan

Based on theWorld Health Organization(WHO),Meningitis is a severe infection of the meninges,the membranes covering the brain and spinal *** is a devastating disease and remains a significant public health *** study investigates a bacterial meningitis model through deterministic and stochastic ***-compartment population dynamics explain the concept,particularly the susceptible population,carrier,infected,and *** model predicts the nonnegative equilibrium points and reproduction number,i.e.,the Meningitis-Free Equilibrium(MFE),and Meningitis-Existing Equilibrium(MEE).For the stochastic version of the existing deterministicmodel,the twomethodologies studied are transition probabilities and non-parametric ***,positivity,boundedness,extinction,and disease persistence are studiedrigorouslywiththe helpofwell-known *** and nonstandard techniques such as EulerMaruyama,stochastic Euler,stochastic Runge Kutta,and stochastic nonstandard finite difference in the sense of delay have been presented for computational analysis of the stochastic ***,standard methods fail to restore the biological properties of the model,so the stochastic nonstandard finite difference approximation is offered as an efficient,low-cost,and independent of time step *** addition,the convergence,local,and global stability around the equilibria of the nonstandard computational method is studied by assuming the perturbation effect is *** simulations and comparison of the methods are presented to support the theoretical results and for the best visualization of results.

关键词： Bacterial Meningitis disease stochastic delayed model stability analysis extinction and persistence computational methods