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Why would sea-level rise for global warming and polar ice-melt?

Geoscience Frontiers 2019年第2期10卷 481-494页

作者： aftab alam khan Department of Geology University of Dhaka

Two major causes of global sea level rise such as thermal expansion of the oceans and the loss of landbased ice for increased melting have been claimed by some researchers and recognized by the ***, other climate threat investigators revealed that atmosphere-ocean modeling is an imperfect representation, paleo-data consist of proxy climate information with ambiguities, and modern observations are limited in scope and accuracy. It is revealed that global warming and polar ice-melt although a reality would not contribute to any sea level rise. Floating-ice of the polar region on melting would reoccupy same displaced volume by floating ice-sheets. Land-ice cover in the polar region on melting can reduce load from the crust to activate elastic rebound that would raise land for its isostatic *** characteristics would not contribute to sea level rise. Equatorial bulge, polar flattening, elevation difference of the spheroidal surface between equator and pole with lower in the pole, strong gravity attraction of the polar region and week gravity attraction of the equatorial region, all these phenomena would play dominant role in preventing sea level rise. Palaeo-sea level rise and fall in macro-scale(10-100 m or so) were related to marine transgression and regression in addition to other geologic events like converging and diverging plate tectonics, orogenic uplift of the collision margin, basin subsidence of the extensional crust, volcanic activities in the oceanic region, prograding delta buildup, ocean floor height change and sub-marine mass avalanche. This study also reveals that geophysical shape, gravity attraction and the centrifugal force of spinning and rotation of the earth would continue acting against sea level rise.

关键词： Global warming Polar ice-melt Equatorial bulge Polar flattening Geologic events Sea level rise

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A Review of the Bentong-Raub Suture vis-à-vis New Insight of the Tectonic Evolution of Malay Peninsula,South East Asia

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Acta Geologica Sinica(English Edition) 2016年第5期90卷 1865-1886页

作者： aftab alam khan Mustaffa Kamal SHUIB Department of Geology University of Malaya Department of Geology University of Dhaka

Genesis of the so-called Bentong-Raub Suture of Malay Peninsula does not fit to the model of subduction-related *** has evolved from transpression tectonics resulting closure and exhumation of the inland basin which underwent extensive back-arc extension during *** having similar thickness（average-35 km） below entire Malay Peninsula nagate collision of two separate continental blocks rather supports single continental block that collided with South China continental block during *** subduction of intervening sea（Proto South China Sea） below Malay Peninsula resulted in widespread I- and S-Type granitization and volcanism in the back-arc basins during *** occurrence of Permo-Triassic Pahang volcanics of predominantly rhyolitic tuff suggest its derivation from back-arc ***-arc extension,basin development and sedimentation of the central belt of the peninsula continued until Cretaceous.A-Type granite of metaluminous to peraluminous character indicates their emplacement in an intraplate tectonic *** Peninsula suffered an anticlockwise rotation due to the rifting of Luconia-Dangerous Grounds from the east Asia in the Late Cretaceous-Early *** ductile and brittle deformation including crustal segmentation,pull-apart fracturing and faulting occurred during the closure and exhumation of the basins developed in the peninsula during Late Cretaceous-Early *** shortening in the central belt of the peninsula has been accomodated through strike-slip displacement,shearing and uplift.

关键词： Bentong-Raub fault intra-plate tectonics Triassic back-arc extension Cretaceoustranspression Malay Peninsula

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Retraction notice to“Why would sea-level rise for global warming and polar ice-melt?”[Geosci Front 10(2019)481-494]

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Geoscience Frontiers 2020年第3期11卷 1093-1093页

作者： aftab alam khan Department of Geology University of DhakaDhaka1000Bangladesh

This article has been retracted at the request of the Editor in Chief of the journal,as the author did not follow ethics in publication and plagiarized contents from online resources and published papers without due *... 详细信息

关键词： please journal polar

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Current updates on the epidemiology,pathogenesis and development of small molecule therapeutics for the treatment of Ebola virus infections

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Asian Pacific Journal of Tropical Medicine 2024年第7期17卷 285-298,I0001-I0007页

作者： Shah alam khan Neelima Shrivastava MdJawaid Akhtar aftab Ahmad Asif Husain Department of Pharmaceutical Chemistry College of PharmacyNational University of Science and TechnologyPO Box 620Postal code 130MuscatSultanate of Oman Centre of Molecular Medicine and Diagnostics(COMMAND) Saveetha Dental College&HospitalsSaveetha Institute of Medical&Technical SciencesSaveetha UniversityChennai 600077India Department of Pharmaceutical Chemistry School of Pharmaceutical Education and ResearchJamia HamdardNew Delhi-110062India Department of Health Information Technology the Applied CollegeKing Abdulaziz UniversityJeddah-21589Kingdom of Saudi Arabia

Ebola virus disease(EVD)is a rare,highly contagious and a deadly disease with a variable fatality rate ranging from 30%to 90%.Over the past two decades,Ebola pandemic has severely affected the sub-Sahara region including Democratic Republic of the Congo(DRC),and *** causative agents of the most EVD cases are three distinct species out of six Ebolaviruses namely Zaire Ebolavirus(ZEBOV),Sudan Ebolavirus(SUDV)and Bundibugyo Ebolavirus(BDBV).In recent years,significant strides have been made in therapeutic ***,the US Food and Drug Administration has approved two monoclonal antibodies:InmazebTM(REGN-EB3)and Ansuvimab or ***,many small molecules are currently in the developmental stage,promising further progress in medical *** the critical need for preventive measures,this review provides an in-depth analysis of the licensed Ebola vaccines-Ervebo and the combination of Zabdeno(***)and Mvabea(MVA-BN-Filo)as well as the vaccines which are currently being tested for their efficacy and safety in clinical *** vaccines might play an important role in curbing the spread and mitigating the impact of this lethal *** current treatment landscape for EVD encompasses both nutritional(supportive)and drug *** review comprehensively details the origin,pathogenesis,and epidemiology of EVD,shedding light on the ongoing efforts to combat this devastating *** explores small molecules in various stages of the development,discusses patents filed or granted,and delves into the clinical and supportive therapies that form the cornerstone of EVD *** review aims to provide the recent developments made in the design and synthesis of small molecules for scientific community to facilitate a deeper understanding of the disease and fostering the development of effective strategies for prevention,treatment,and control of EVD.

关键词： Ebola Epidemic Vaccine Ebola virus diseas

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Sagbi-Gröbner Bases Under Composition

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Journal of Systems Science & Complexity 2023年第5期36卷 2214-2224页

作者： KANWAL Nazish khan Junaid alam Department of Sciences&Humanities FAST-National University of Computer&Emerging SciencesKarachicampusPakistan Department of Mathematical Sciences School of Mathematics and Computer ScienceInstitute of Business AdministrationKarachiPakistan

The process of substituting variables in a polynomial with other polynomials is dubbed polynomial *** behaviour of Gröbner bases and Sagbi bases under composition is well *** this paper,the authors provide a sufficient and necessary condition on a setΘof polynomials under which the Sagbi-Gröbner basis computation commutes with *** has natural applications to the computations of Sagbi-Gröbner bases for subsets of composed polynomials of subalgebra.

关键词： Polynomial composition sagbi bases Sagbi-Gr?bner bases

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Utilizing the γ-Irradiated Sodium Alginate as a Plant Growth Promoter for Enhancing the Growth,Physiological Activities,and Alkaloids Production in Catharanthus roseus L.

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Agricultural Sciences in China 2011年第8期10卷 1213-1221页

作者： Mohd Idrees Mohd Naeem Masidur alam Tariq aftab Nadeem Hashmi Mohd Masroor Akhtar khan Moinuddin Lalit Varshney Department of Botany Aligarh Muslim University Bhabha Atomic Research Centre

Sodium alginate is a polysaccharide that is largely obtained from the brown algae （Sargassum sp.）.It has been used as a wonderful growth promoting substance in its depolymerized form for various *** aim of this study was to find out the effects of various concentrations of γ-irradiated sodium alginate （ISA）,viz.,deionized water （control,T0）,20 （T1）,40 （T2）,60 （T3）,80 （T4）,and 100 ppm （T5） on the agricultural performance of Catharanthus roseus L.（Rosea） in terms of growth attributes,photosynthesis,physiological activities,and alkaloid *** present work revealed that ISA applied as leaf-sprays at concentrations from 20 to 100 ppm might improve growth,photosynthesis,physiological activities,and alkaloid production in *** *** the various ISA concentrations,80 ppm proved to be the best one compared to other concentrations applied.

关键词： γ-irradiated sodium alginate plant growth promoter chlorophyll and carotenoids content carbonic anhydrase and nitrate reductase activities growth attributes photosynthesis

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An Implementation of Haar Wavelet Based Method for Numerical Treatment of Time-fractional Schrdinger and Coupled Schrdinger Systems

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IEEE/CAA Journal of Automatica Sinica 2019年第1期6卷 177-187页

作者： Najeeb alam khan Tooba Hameed the Department of Mathematics University of Karachi

The objective of this paper is to solve the timefractional Schr¨odinger and coupled Schr¨odinger differential equations(TFSE) with appropriate initial conditions by using the Haar wavelet approximation. For the most part, this endeavor is made to enlarge the pertinence of the Haar wavelet method to solve a coupled system of time-fractional partial differential equations. As a general rule, piecewise constant approximation of a function at different resolutions is presentational characteristic of Haar wavelet method through which it converts the differential equation into the Sylvester equation that can be further simplified easily. Study of the TFSE is theoretical and experimental research and it also helps in the development of automation science,physics, and engineering as well. Illustratively, several test problems are discussed to draw an effective conclusion, supported by the graphical and tabulated results of included examples, to reveal the proficiency and adaptability of the method.

关键词： Fractional calculus Haar wavelets operational matrix wavelets

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Chemical modification of acetaminophen：PASS assisted in vivo antiinflammatory activity of chalcones,flavanones and Schiff bases

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Journal of Chinese Pharmaceutical Sciences 2017年第8期26卷 611-620页

作者： Syed Misbahul Hasan Shah alam khan Kavita Golani Jaswinder Lamba aftab Ahmad Asif Husain Department of Pharmaceutical Chemistry School of Pharmaceutical Education and Research Jamia Hamdard (Hamdard University)New Delhi 110062 India Faculty of Pharmacy Integral University Lucknow UP 226026 India Department of Pharmacy Oman Medical College PO Box 620 Postal code-130 Muscat Sultanate of Oman Health Information Technology Department Jeddah Community College King Abdulaziz University deddah Kingdom of Saudi Arabia

In the present study,synthetic chalcones,flavanones and Schiff bases were prepared starting from paraceamol,and evaluated their anticipated anti-inflammatory *** were synthesized by reacting 3-acetyl-4-hydroxy acetanilide and aromatic aldehydes in alcoholic potassium hydroxide(KOH) solution under Claisen-Schmidt condensation *** chalcones were cyclized in the presence of piperidine in isoamyl alcohol to obtain flavonone *** bases were synthesized by condensing 3-acetyl-4-hydroxy anilines with aromatic aldehydes in the presence of *** Schiff bases were further reacted with other aromatic aldehydes in alcoholic KOH *** cheminformatics software was used to predict the anti-inflammatory activity of synthesized *** software predicted that chalcone-based Schiff bases 6a–d contained structural features that can exhibit anti-inflammatory *** the prepared derivatives of acetaminophen exhibited moderate to excellent in vivo anti-inflammatory activity in carrageenan-induced edema in rat *** the Schiff bases coupled chalcones showed good anti-inflammatory activity compared with the reference drug,*** evaluation of their therapeutic potential and safety profile is required in the future study.

关键词： p-Acetaminophen Anti-inflammatory Chalcone Flavanone

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Repurposing of FDA-Approved drugs to predict new inhibitors against key regulatory genes in Mycobacterium tuberculosis

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BIOCELL 2021年第6期45卷 1569-1583页

作者： XINJUN YANG aftab alam NAIYAR IQBAL KHALID RAZA Department of Pediatrics 3201 HospitalHanzhongChina Centre for Interdisciplinary Research in Basic Sciences Jamia Millia IslamiaNew DelhiIndia Department of Computer Science and Information Technology Maulana Azad National Urdu UniversityHyderabadIndia Department of Computer Science Jamia Millia IslamiaNew DelhiIndia

Tuberculosis(TB)disease has become one of the major public health concerns globally,especially in developing *** research studies have already been carried out for TB,but we are still struggling for a complete and quick cure for *** progress of Mycobacterium tuberculosis(MTB)strains resistant to existing drugs makes its cure and control very ***,it is the need of the hour to search for newer and effective drugs that can inhibit an increasing number of putative drug *** applied the drug repurposing concept to identify promising FDAapproved drugs against five key-regulatory genes(FurB,IdeR,KstR,MosR,and RegX3)of the *** FDA drugs were virtually screened using a structure-based approach by GOLD versions 5.2,and subjected to rigid docking followed by an induced-fit docking algorithm to enhance the accuracy and prioritize drugs for *** found 11 candidate drugs(including ZINC03871613,ZINC03871614,ZINC03871615 as top scorer candidate drugs)that were frequently present within the top 20 GoldScore ranks and showed promising ***,molecular dynamics simulation was performed to monitor the effect of the top scorer drugs on the structural stability of all the five targets,indicating that inhibitors preferentially bind to the active site of the *** work suggests that these known FDA-approved drugs open new application domains in the form of anti-tuberculosis agents.

关键词： Virtual screening Molecular docking MD simulation PPI network

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Food habits of striped hyena(Hyaena hyaena) in a semi-arid conservation area of India

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Journal of Arid Land 2015年第6期7卷 860-866页

作者： M Shamshad alam Jamal A khan Department of Wildlife Sciences Aligarh Muslim University

Striped hyena（Hyaena hyaena） is a near-threatened large carnivore known to occur in arid and semi-arid landscapes in many parts of the world. Its population is declining globally and ecological information is required urgently to meet their conservation needs. We studied the diet pattern of the striped hyena in the semi-arid Gir National Park and Sanctuary（GNPS）, western India. Prey items eaten by the striped hyena were identified from scats. Around 44.4% scats represented single to three mammalian preys while 55.6% of them represented four preys to seven preys. A variety of food items were identified including mammals, birds, insects and vegetable matters. Scats analysis showed that 63.91% diet of striped hyena was contributed by wild prey items, 20.94% by domestic prey and 3.31% by birds, whereas vegetable and insects contributed 9.92% and 1.93%, respectively. Diet diversity of the striped hyena computed by the Shannon-Weiner Index（H） was found to be 2.64. The presence of domestic mammals in the scat remains implied that the striped hyena might frequently visit human habitation in search for food and hence, a potential conflict between human and wildlife might arise. Reducing the dependence of hyena on domestic livestock is a challenge to ensure the survival of striped hyena outside the protected area.

关键词： diet pattern Gir National Park and Sanctuary Hyaena hyaena scat analysis

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