检索结果-南通市图书馆

Indistinguishable cellular changes in gastric mucosa between Helicobacter pylori infected asymptomatic tribal and duodenal ulcer patients

引用

World Journal of Gastroenterology 2009年第9期15卷 1105-1112页

作者： Dhira Rani Saha Simanti Datta Santanu Chattopadhyay Rajashree Patra Ronita De Krishnan Rajendran abhijit Chowdhury Thandavaryan Ramamurthy Asish Kumar Mukhopadhyay Division of Histology & Electron microscopy. National Institute of Cholera and Enteric Diseases P 33 CIT Road Scheme XM Beliaghata Kolkata 700010 India School of digestive diseases Institute of Post Graduate Medical Education and Research 244 AJC Bose Road Kolkata 700020 India Division of Bacteriology National Institute of Cholera and Enteric Diseases P 33 CIT Road Scheme XM Beliaghata Kolkata 700010 India Data management Division National Institute of Cholera and Enteric Diseases P 33 CIT Road Scheme XM Beliaghata Kolkata 700010 India

AIM： To investigate the changing pattern of different histological parameters occurring in the stomach tissue of Helicobacter pylori （H pylori） infected tribal populations and duodenal ulcer patients among ethnic Bengalis and correlation of the genotypes of H pylori with different histological parameters. METHODS： One hundred and twelve adult individuals were enrolled into this study between 2002 and 2004. Among them, 72 had clinical features of duodenal ulcer （DU） from ethnic Bengali population and 40 were asymptomatic ethnic tribals. Endoscopic gastric biopsy samples were processed for histology, genotyping and rapid urease test. Histologically, haematoxylin and eosin staining was applied to assess the pathomorphological changes and a modified Giemsa staining was used for better detection of Hpylori. For intestinal metaplasia, special stainings, i.e. Alcian blue periodic acid-Schiff and high iron diamine-Alcian blue staining, were performed. PCR was performed on bacterial DNA to characterize the presence or absence of virulence-associated genes, like cagA, and distribution of different alleles of vacA and iceA. RESULTS： Intraglandular neutrophil infiltration, a hallmark of activity of gastritis, was present in 34 （94%） of tribals （TRs） and 42 （84%） of DU individuals infected with H pylori. Lymphoid follicles and aggregates, which are important landmarks in H pylori infection, were positive amongst 15 （41%） of TRs and 20 （40%） of DU subjects. Atrophic changes were observed in 60% and 27.7%, respectively, among DU cases and tribals （P 〉 0.003）. Metaplastic changes were detected in low numbers in both groups. Moderate to severe density distribution of Hpylori in the gastric mucosa was 63% among TRs, whereas it was 62% in DU subjects. There were no significant differences in the distribution of virulence-associated genes like cagA, vacA and iceA of H pylori strains carried by these two populations. CONCLUSION： Our study showed almost similar distribution of inflammato

关键词： Helicobacter pylori Tribal Neutrophil Mononuclear cells infiltration Lymphoid follicles

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer chemotherapy and beyond:Current status,drug candidates,associated risks and progress in targeted therapeutics

引用

Genes & Diseases 2023年第4期10卷 1367-1401页

作者： Uttpal Anand abhijit Dey Arvind K.Singh Chandel Rupa Sanyal Amarnath Mishra Devendra Kumar Pandey Valentina De Falco Arun Upadhyay Ramesh Kandimalla Anupama Chaudhary Jaspreet Kaur Dhanjal Saikat Dewanjee Jayalakshmi Vallamkondu José M.Pérez de la Lastra Department of Life Sciences Ben-Gurion University of the NegevBeer-Sheva 84105Israel Department of Life Sciences Presidency UniversityKolkataWest Bengal 700073India Center for Disease Biology and Integrative Medicine Faculty of MedicineThe University of TokyoTokyo 113-0033Japan Department of Botany Bhairab Ganguly College(affiliated to West Bengal State University)KolkataWest Bengal 700056India Faculty of Science and Technology Amity Institute of Forensic SciencesAmity University Uttar PradeshNoida 201313India Department of Biotechnology School of Bioengineering and BiosciencesLovely Professional UniversityPhagwaraPunjab 144411India Institute of Endocrinology and Experimental Oncology(IEOS) National Research Council(CNR)Department of Molecular Medicine and Medical Biotechnology(DMMBM)University of Naples Federico IINaples 80131Italy Department of Biochemistry School of Life SciencesCentral University of RajasthanBandar SindariKishangarh AjmerRajasthan 305817India CSIR-Indian Institute of Chemical Technology HyderabadTelangana 500007India Department of Biochemistry Kakatiya Medical CollegeWarangalTelangana 506007India Orinin-BioSystems LE-52Lotus Road 4CHD CityKarnalHaryana 132001India Department of Computational Biology Indraprastha Institute of Information Technology Delhi(IIIT-D)Okhla Industrial EstatePhase IIINew Delhi 110020India Advanced Pharmacognosy Research Laboratory Department of Pharmaceutical TechnologyJadavpur UniversityKolkata 700032India Department of Physics National Institute of Technology-WarangalWarangalTelangana 506004India Biotechnology of Macromolecules Research Group Instituto de Productos Naturales y AgrobiologíaIPNA-CSICSan Cristóbal de La Laguna 38206TenerifeSpain

Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and produce aggressive malignancies that causes millions of deaths every *** the new understanding of the molecular mechanism(s)of disease progression,our knowledge about the disease is snowballing,leading to the evolution of many new therapeutic regimes and their successive *** the past few decades,various combinations of therapies have been pro-posed and are presently employed in the treatment of diverse *** drug therapy,immunotherapy,and personalized medicines are now largely being employed,which were not common a few years *** field of cancer discoveries and therapeutics are evolving fast as cancer type-specific biomarkers are progressively being identified and several types of cancers are nowadays undergoing systematic therapies,extending patients’disease-free survival *** growing evidence shows that a systematic and targeted approach could be the future of cancer medicine,chemotherapy remains a largely opted therapeutic option despite its known side effects on the patient’s physical and psychological ***-apeutic agents/pharmaceuticals served a great purpose over the past few decades and have remained the frontline choice for advanced-stage malignancies where surgery and/or radiation therapy cannot be prescribed due to specific *** present report succinctly reviews the existing and contemporary advancements in chemotherapy and assesses the status of the enrolled drugs/pharmaceuticals;it also comprehensively discusses the emerging role of specific/targeted therapeutic strategies that are presently being employed to achieve better clinical success/survival rate in cancer patients.

关键词： Antimicrobial peptides Cancer therapies Clinical trials Combination therapy Immunotherapy Patient survival Personalized medicine Targeted drug delivery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Over expression of resistin in adipose tissue of the obese induces insulin resistance

引用

World Journal of Diabetes 2012年第7期3卷 135-141页

作者： Sadashiv Sunita Tiwari S Dhananjai Bhola N Paul Sandeep Kumar abhijit Chandra Mahendra PS Negi Department of Physiology CSM Medical UniversityLucknow 226003 India Immunobiology Division Indian Institute of Toxicological ResearchLucknow 226001 India Department of Surgery CSM Medical UniversityLucknow 226003 India Department of Gastroenterology CSM Medical UniversityLucknow 226003 India Institute for Data Computing and Training Lucknow 226021 India

AIM: To compare resistin mRNA expression in subcutaneous adipose tissue (SAT) and its correlation with insulin resistance (IR) in postmenopausal obese women. METHODS: A total of 68 postmenopausal women (non obese = 34 and obese = 34) were enrolled for the study. The women of the two groups were age matched (49-70 years). Fasting blood samples were collected at admission and abdominal SAT was obtained during surgery for gall bladder stones or hysterectomy. Physical parameters [age, height, weight, body mass index (BMI)] were measured. Biochemical (plasma insulin and plasma glucose) parameters were estimated by enzymatic methods. RNA was isolated by the Trizol *** resistin mRNA expression was done by real time- reverse transcription polymerase chain reaction (RT-PCR) by using Quanti Tect SYBR Green RT-PCR master mix. Data was analyzed using independent Student's t test, correlation and simple linear regression analysis. RESULTS: The mean weight (52.81 ± 8.04 kg vs 79.56 ± 9.91 kg; P < 0.001), BMI (20.23 ± 3.05 kg/m 2 vs 32.19 ± 4.86 kg/m 2 ; P < 0.001), insulin (8.47 ± 3.24 U/mL vs 14.67 ± 2.18 U/mL; P < 0.001), glucose (97.44 ± 11.31 mg/dL vs 109.67 ± 8.02 mg/dL; P < 0.001) and homeostasis model assessment index (2.01 ± 0.73 vs 3.96 ± 0.61; P < 0.001) were significantly higher in postmenopausal obese women compared to postmenopausal non obese women. The mean serum resistin level was also significantly higher in postmeno-pausal obese women compared to postmenopausal non obese women (9.05 ± 5.15 vs 13.92 ± 6.32, P < 0.001). Furthermore, the mean SAT resistin mRNA expression was also significantly (0.023 ± 0.008 vs 0.036 ± 0.009; P < 0.001) higher and over expressed 1.62 fold (upregulated) in postmenopausal obese women compared to postmenopausal non obese women. In postmeno-pausal obese women, the relative SAT resistin mRNA expression showed positive (direct) and significant correlation with BMI (r = 0.78, P < 0.001) and serum resistin (r = 0.76, P < 0.001). Furt

关键词： Resistin Subcutaneous adipose tissue Insu-lin resistance Obesity Body mass index

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Minimization of Air Consumption and Potential Savings of Textile Denim Fabric Manufacturing Process

引用

Journal of Textile Science and Technology 2023年第1期9卷 69-83页

作者： Md. Enamul Haque Md. Bokthier Rahman Waliul Kafi Md. Suja Uddin Kaiser abhijit Dey Khulna University of Engineering & Technology (KUET) Khulna Bangladesh Bangladesh University of Textiles (BUTEX) Dhaka Bangladesh

One of the most important aspects of Bangladesh’s textile industry is denim. Bangladesh now has a new opportunity thanks to the global demand for denim among fashion industry professionals. Entrepreneurs from Bangladesh provide denim products to well-known international merchants all over the world. The worldwide denim market is predicted to expand by roughly 8% through the year 2020. We must raise the standard of denim if we are to keep up with the expanding industry. In contrast to projectile and rapier systems, air-jet weaving machines nowadays can weave practically all types of yarns without any issues and at higher rates. Due to this, air-jet looms are an excellent substitute for other weft insertion techniques. This kind of device still has one significant flaw, though, and that is the enormous power consumption brought on by the creation of compressed air. Researchers and manufacturers of air-jet looms have therefore worked very hard to find a solution to this issue and achieve a huge reduction in air consumption without compromising loom performance or fabric quality. Therefore, the purpose of this project is to look into ways to decrease air consumption and reduce auxiliary selvedge waste without any decrease in loom performance and fabric quality on existing air-jet weaving looms which reduce the manufacturing costs with process improvement. Just updating the air pressure allowed a weaving mill to reduce air usage by 11 cfm. So, with just almost no cost, a company with 100 looms could save $0.15 M each year, on compressed air. Two new methods for decreasing process costs on air jet looms have also been developed by this project work.

关键词： Denim Woven Textiles Weaving Machine Air Consumption Cost Reduction Waste Reduction Potential Savings

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

机顶盒带内实现多应用协调和查询式应用调用

引用

有线电视技术 2000年第12期7卷 57-61页

作者： abhijit Chatterjee Navneeth Kannan

如今,先进的模拟机顶盒都具备很大的内存容量,以便于为用户提供大量的应用。随着电缆经营商们以及用户们对机顶盒多功能用途的不断认识,他们对一些新的以及先进的交互式应用的需求也随之增长。那么,这些应用之间的协调问题和内存节省开... 详细信息

如今,先进的模拟机顶盒都具备很大的内存容量,以便于为用户提供大量的应用。随着电缆经营商们以及用户们对机顶盒多功能用途的不断认识,他们对一些新的以及先进的交互式应用的需求也随之增长。那么,这些应用之间的协调问题和内存节省开支问题也就成为机顶盒软件设计人员所面对的两个主要问题。

关键词：机顶盒多应用协调查询式应用调用

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-systemic melioidosis

引用

World Journal of Clinical Cases 2024年第28期12卷 6151-6154页

作者： Basavraj S Nagoba Shree V Dhotre abhijit S Rayate Sachin S Mumbre Pradnya S Dhotre Department of Microbiology Maharashtra Institute of Medical Sciences and Research(Medical College)Latur 413531India Department of Microbiology Ashwini Rural Medical CollegeSolapur 413001India Department of Surgery Maharashtra Institute of Medical Sciences and Research(Medical College)Latur 413531India Department of Community Medicine Ashwini Rural Medical CollegeSolapur 413006India Department of Biochemistry Ashwini Rural Medical CollegeSolapur 413001India

This editorial is a commentary on the article by Ni et al,which was published in the World Journal of Clinical *** article discusses the diagnostic and therapeutic challenges of melioidosis caused by Burkholderia *** case study highlights a rare instance of multisystemic melioidosis in a female patient who did not have a travel history,emphasizing the significance of recognizing this condition in non-endemic *** complexities and therapeutic strategies are addressed,emphasizing the need for heightened clinical suspicion,comprehensive evaluation,and multidisciplinary *** editorial delves into the clinical presentation,diagnostic dilemmas,therapeutic approaches,and their implications for patient care in managing multi-systemic melioidosis.

关键词： Melioidosis Burkholderia pseudomallei Multi-systemic Diagnosis Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

英国医学院校的公共卫生本科教育改革

引用

复旦教育论坛 2007年第4期5卷 85-88页

作者： Stephen Gillam abhijit Bagade 魏芬上海理工大学教务处上海200093

随着公共卫生在政策体系中地位的上升,该领域的教学问题也越来越重要。本文主要通过对英国医学院校公共卫生教学现状的调查,分析本科医学课程的教学投入和现有教学资源状况;探讨公共卫生教学面临的挑战及其对策。

关键词：公共卫生医学本科教育教学英国

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

神经网络模式识别及其实现

引用

1999年

作者：（美）（A.S.潘迪）abhijit S.Pandya （美）（R.B.梅西）Robert B.Macy 徐勇等译

本书主要包括：概述、预处理、有监督学习的前馈网络、其它类型的神经网络、特征提取等。

ISBN: (纸本)7505350889

本书主要包括：概述、预处理、有监督学习的前馈网络、其它类型的神经网络、特征提取等。

关键词：神经网络模式识别

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

脂肪酸改性炭黑性能的分析

引用

橡胶科技市场 2010年第8期8卷 10-14页

作者： abhijit Adhikary 朱永康

介绍利用市售试剂过氧化二异丙苯和N-1,3-二甲基丁基-N′-苯基对苯二胺和长链脂肪酸混合物对炭黑表面进行改性,并通过不同分析手段对改性炭黑的特征和性能进行了研究和表征,分析了影响改性炭黑性能的因素。

关键词：炭黑脂肪酸改性过氧化物表面附着

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Higher dimensional bianchi type-V universe in creation-field cosmology

引用

Natural Science 2010年第5期2卷 484-488页

作者： Kishor S. Adhav Shivdas D. Katore abhijit S. Bansod Prachi S. Gadodia 不详

We have studied the Hoyle-Narlikar C-field cosmology with Bianchi type-V non static space- time in higher dimensions. Using methods of Narlikar and Padmanabham [1], the solutions have been studied when the creation field C is a function of time t only as space time is non static. The geometrical and physical aspects for model are also studied.

关键词： Bianchi Type-V Space-Time Creation Field Cosmology Cosmological Model of Universe Higher Dimensions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：