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Concentration of Selected elements in the Tissues of the Knee Joint

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Biomedical and Environmental Sciences 2020年第10期33卷 807-811页

作者： BABUSka-ROCZNIAK Magdalena BRODZIAK-DOPIERALA Barbara MITKO Krzysztof CIPORa.elzbieta ROCZNIAK Wojciech The Jan Grodek State University in Sanok Medical Institute38-500 SanokPoland Department of Toxicology and Bioanalysis Faculty of Pharmaceutical ScienceMedical University of Silesia41-200 SosnowiecPoland Central Mining Institute The Laboratory of Water and Sewage Analyses40-166 KatowicePoland

The remodeling processes that occur in bone tissue allow for proper functioning and can lead to the inclusion of additional elements,including toxic ones,in the remodeled *** condition in turn affects the metabolic processes in the bond,which may result in disturbances to the bone-joint system,as manifested by changes in bone tissue and other organs[1].

关键词： organs remodeling bone

Tuberculosis among Chronic Hemodialysis Patients: A Senegalese Single Center Experience

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Open Journal of Nephrology 2015年第4期5卷 117-122页

作者： Mouhamadou Moustapha Cisse Rachid el ka.ouss Yaya kane Sidy Mouhamed Seck Ahmed Tall Lemrabott Maria Faye el Hadji Fary ka Ansoumana Diatta Abdou Niang Boucar Diouf Nephrology Department of Teaching Hospital Aristide le Dantec Dakar Senegal Department of Nephrology Assane Seck University Ziguinchor Senegal Department of Nephrology Gaston Berger University Saint Louis Senegal

Summary: Tuberculosis is a common infectious disease in chronic hemodialysis due to alteration of the immune system associated with chronic kidney disease. The objectives of this study are to determine the prevalence of tuberculosis in chronic hemodialysis patients and to identify its diagnostic and therapeutic difficulties. Methods and patients: This was a descriptive retrospective study over a period of 20 years (1994-2014). It includes the records of periodic hemodialysis patients in the Nephrology Department of the Aristide Le Dantec University Teaching Hospital in Dakar which clinical symptoms and laboratory favor tuberculosis. Results: Of 258 chronic hemodialysis patients treated in Hospital Aristide Le Dantec hemodialysis center, 29 cases (11.4%) of tuberculosis disease are diagnosed. The mean age is 43.21 ± 12.48 years, and the sex-ratio is 0.8. The median time to onset of tuberculosis after initiation of hemodialysis is 22.86 ± 28.86 months. The diagnosis of tuberculosis is sure only in 17% of cases. Extra-pulmonary sites are found in 79% of cases. The average duration of treatment is 9.39 ± 1.64 months (6 - 13 months). Various treatment protocols are adopted. Mortality is 21%, 50% due to disseminated tuberculosis. Conclusion: The diagnosis of tuberculosis in the chronic hemodialysis patients is often difficult due to the atypical symptoms, the frequency of extra-pulmonary location and the lack of evidence of sure diagnosis.

关键词： Tuberculosis Hemodialysis Dakar

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钒和钛微合金化钢的二次硬化

国外低合金钢（合金钢） 1990年第1期 33-36页

作者： el－F.,ka 吕延坤

Curative 3D Conformal Radiotherapy of Non-Operated Prostate Adenocarcinoma at Pointe-a-Pitre University Hospital (Gua.eloupe): About 29 Cases

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Journal of Cancer Therapy 2021年第5期12卷 279-288页

作者： Ibrahima Thiam kanta ka Awa Sadikh Badiane Mouhamadou Bachir Bâ el Hadj Amadou Sall Boucar Ndong Papa Ahmet Fall Mamadou Moustapha Dieng Papa Macoumba Gaye Joliot Curie Institute of Aristide Le Dantec Hospital Dakar Senegal Radiotherapy Department of the University Hospital Center of Dalal Jamm Guédiawaye Senegal Cheikh Anta Diop University Dakar Senegal Urology Department of the University Hospital Center of Dalal Jamm Guédiawaye Senegal

Context: Technological advances have improved the toxicities of radiotherapy. We are evaluating the 3D technique in prostate cancer. Materials and Methods: Retrospective study from January 2015 to December 2015 with 29 files. Survival was calculated by Kaplan-Meier method. Results: We collected 29 patient records over the study period. The median age was 75 years with the following extremes: 54 years and 83 years. The median PSA level was 12 ng/ml with a range of 3.05 to 79 ng/ml. Gleason score analysis showed 6 patients (20.69%) with a score of 6 (3 + 3), 23 patients (79.31%) with a score of 7 including 12 patients (41.38%) with grade 3 and 11 patients (37.93%) with grade 4. The median dose delivered was 74 Gy, with a mean dose of 73.79 Gy and extremes of 70 Gy for the minimum and 76 Gy for the maximum. Hormone therapy was combined with radiotherapy in 17 patients (58.62%). Seven patients (24.14%) had grade 1 acute bladder toxicity and one patient (3.45%) had grade 2 acute toxicity. Late bladder toxicity was grade 1 in 5 patients (17.24%), grade 2 in 3 patients (10.34%) and grade 3 in 1 patient (3.45%). Late rectal toxicity, grade 2 in 3 patients (10.34%), grade 3 in 1 patient, was noted. Overall survival at 2 years was 100% and 89.65% at 5 years. Relapse-free survival at 2 years was 82.76% and 62.07% at 5 years. There were 3 deaths (10.34%) of which only one was related to prostate cancer.

Quality of Life of Patients on Peritoneal Dialysis in Dakar: A Senegalese Single Centre Experience

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Open Journal of Nephrology 2016年第2期6卷 37-42页

作者： kane Yaya Cisse Mouhamadou Moustapha Seck Sidy Mohamed Lemrabott Ahmed Tall Faye Maria Hounsounou Christian Diallo kalilou Ka.el Hadji Fary Niang Abdou Diouf Boucar Nephrology and Internal Medicine Department of Assane Seck University Ziguinchor Senegal Nephrology Department of Teaching Hospital Aristide Le Dantec Dakar Senegal Nephrology Department of Gaston Berger University Saint-Louis Senegal

Introduction: Measuring the quality of life (QOL) in recent years has become an indispensable tool in monitoring patients suffering from chronic diseases. We conducted this study to assess QOL of patients undergoing peritoneal dialysis in Dakar, and to identify associated factors. Patients and Methods: This is a cross-sectional study which was carried out from 10 to 30 June, 2011 in the peritoneal dialysis unit at university hospital in Dakar. We included all patients with end-stage renal disease (ESRD) of any age, who were on PD since at least six months and who gave their consent. The QOL was assessed using the Kidney Disease Quality of Life Short-Form 1.2 (KDQoL-SF). Results: Sixteen patients were included with a mean age of 50.25 ± 13.48 years and a sex-ratio of 1.27. Considering SF-36, the overall mean score (SMG) was 60.11 ± 15.96 with a Mean Physical Component Summary Scale of 53.66 ± 16.98 and a Mental Component Summary Scale of 70.85 ± 6.14. Concerning the KDQoL-SF, the global mean score was 61.83 ± 19.35 with a mean physical score of 50.55 ± 16.52 and a mean mental score of 62.52 ± 21.53. The mean dialysis specific dimension score was 62.52 ± 21.53 and the mean mental health score was 85.93 ± 12.06. Age, weight, level of instruction and social support were correlated with a worse QOL. Conclusion: This study showed an alteration of our PD patients’ QOL, particularly in their physical health. However, the number of patients included in the study is not enough to permit a formal conclusion.

关键词： Quality of Life Peritoneal Dialysis Dakar

Peripheral Arterial Disease among Patient Undergoing Maintenance Hemodialysis in Dakar (Senegal)

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Open Journal of Nephrology 2021年第2期11卷 242-251页

作者： Habin Yabama Aida Lengani Mouhamadou Moustapha Cissé Hamadoun Yattara Alassane Mbaye Gérard Coulibaly Joseph Salvador Mingou el Hadj Fary ka Abdou Niang Abdoul kane Boucar Diouf Departement of Nephrology University Hospital Yalgado Ouédraogo Ouagadougou Burkina Faso Departement of Nephrology University Hospital Aristide le Dantec Dakar Sénégal Departement of Nephrology University Hospital of Point G Bamako Mali Departement of Cardiology National Hospital Grand Yoff Dakar Sénégal Cheikh Anta Diop University Dakar Sénégal

Background: Peripheral arterial disease (PAD) is common in patients with chronic kidney disease (CKD). It is a surrogate marker of generalized atherosclerosis. In sub-Saharan Africa, PAD remains understudied in CKD. Ankle-brachial index (ABI) is a non-invasive and cost-effective tool to diagnose PAD. Objectives: Our aim was to determine the prevalence and associated risk factors for PAD in hemodialysis patients. Patients and Methods: We conducted a cross-sectional study from July 1 to December 31, 2012 in the department of Nephrology of the University Hospital Aristide le Dantec of Dakar. All consenting patients, aged above 18 years, on hemodialysis for at least 6 months were included. ABI measurements were performed using a handled pulse doppler. PAD was defined as an ABI of Results: A total of 53 patients with a mean age of 49.15 ± 15.18 were included. The sex ratio was 0.70. Hypertension (83.01%), low HDL-cholesterol (26.41%) and cigarette smoking (20.75%) were the main cardiovascular risk factors. Prevalence of PAD was 47.16%. Among patients with PAD, 52% had no suggestive symptoms. Lower pre-dialysis (p = 0.0384) and post-dialysis (p = 0.0447) diastolic blood pressure (BP) were significantly associated with PAD. The conventional risk factors (tobacco consumption, diabetes, alcohol consumption, dyslipidemia, hypertension, age), iPTH and CRP levels were not correlated with PAD. Conclusion: PAD is common among patients undergoing maintenance hemodialysis in Senegal. Early diagnosis and management of PAD should be routinely performed in CKD patients.

关键词： Ankle Brachial Index Peripheral Arterial Disease Hemodialysis

Correlation between Glomerulopathy and Retinopathy in an African Population of Type 2 Diabetics

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Journal of Diabetes Mellitus 2020年第2期10卷 64-72页

作者： Michel Assane Ndour Jean Pierre Diagne Demba Diedhiou Djiby Sow Esperance Ciss Ibrahima Mane Diallo Muriel Diembou el Hadj Fary ka Papa Amadou Ndiaye Anna Sarr Maimouna Ndour Mbaye Department of Internal Medicine Abass Ndao Hospital Center Dakar Sénégal Department of Ophtalmology Abass Ndao Hospital Center Dakar Sénégal Department of Nephrology Aristide Le DantecHospital Center Dakar Sénégal

Introduction: Diabetic microangiopathies are common, but their time to onset in a diabetic patient varies from subject to subject. The aim of our study was to study the correlation between renal and ophthalmic disorders in patients with type 2 diabetes. Patients and methods: This longitudinal, analytical study took place from March 1, 2018 to March 31, 2019 at the Abass Ndao University Hospital Center. It was studying retinal involvement in diabetic patients with glomerulopathy. Results: Of the 100 cases of diabetic glomerulopathy, they are divided into 70 women and 30 men with an average age of 58.2 years. The average duration of diabetes was 6.1 years and their average glycated hemoglobin (HbA1c) was 8.1%. Only 37% of patients had an HbA1c level below 7%. The other cardiovascular risk factors were high blood pressure (HBP) (39%), dyslipidemia (36%), and obesity (15%). Among these patients, diabetic retinopathy was present in 21% of the cases. Retinopathies were more frequent in the group of patients diagnosed with diabetes for less than 6 years (69%) and in patients with chronic renal disease with slightly reduced glomerular filtration rate (GFR) (34%). Conclusion: Our study allowed us to conclude that during the course of type 2 diabetes, the onset of chronic kidney disease does not systematically imply the presence of diabetic retinopathy. It is thus important to make screenings and assessments of systematic complications.

关键词： Diabetic Retinopathy Diabetic Nephropathy Microangiopathy Daka

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下颌角肥大整形术相关解剖

解剖学报 2018年第5期49卷 660-665页

作者：陈卡娜邵正仁范华李理 MARIYA M.el Akka wi 颜玲宁波市第二医院整形美容科浙江宁波315010 蚌埠医学院解剖学教研室安徽蚌埠2330030 中山大学附属第三医院整形美容科广州510630

目的精细解剖下颌角周围软组织结构及下颌神经管,为下颌角肥大整形术提供解剖学参考。方法20例大体标本,观察及测量面动静脉、面神经下颌缘支及咬肌区的血管和神经。据下颌骨表面骨性标志定位5条径线,测量该5条径线上下颌神经管在下颌... 详细信息

目的精细解剖下颌角周围软组织结构及下颌神经管,为下颌角肥大整形术提供解剖学参考。方法20例大体标本,观察及测量面动静脉、面神经下颌缘支及咬肌区的血管和神经。据下颌骨表面骨性标志定位5条径线,测量该5条径线上下颌神经管在下颌骨中的位置。计算各软组织结构和下颌神经管的安全范围。结果面动脉距下颌角点为23. 18~36. 28 mm,距咬肌前缘为-9. 51~9. 27 mm。面静脉距离下颌角点为17. 79~32. 03mm。面神经下颌缘支贴近下颌角部及下颌骨下缘走行,距离下颌角点为-8. 57~10. 70 mm,而咬肌前缘下颌缘支距下颌骨下缘为-8. 83~11. 06 mm。咬肌的血供主要有面动脉咬肌支、颈外动脉咬肌支、上颌动脉咬肌支及面横动脉咬肌支这四大来源。咬肌神经多与咬肌动脉伴行进入咬肌。下颌神经管在5个截面中距离下颌骨外侧点分别大于10. 50 mm、14. 72 mm、15. 60 mm、8. 53 mm、6. 74 mm。结论在剥离下颌角区软组织时,注意对咬肌前缘面动脉、面神经下颌缘支及下颌角点附近面神经下颌缘支的保护。去除咬肌的最佳层次为咬肌深层中份最厚点及中下份。而在截骨或劈骨时,根据下颌神经管的安全范围,可在下颌骨颊侧骨板快速画出一条指导性的安全线。

关键词：下颌角肥大下颌神经管截骨解剖学成人

Compressive Myeloradiculopathies in Multiple Myeloma: Clinical and Radiological Characteristics of a Series of 29 Patients

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Open Journal of Blood Diseases 2021年第4期11卷 133-139页

作者： el Hadji Daouda Niang Mbodji Ahmadou Bamba ka Mamadou Fall Seynabou Seck Moussa Mbaye Khalifa Ababacar Bousso elimane Sarr Khadim Faye Atoumane Ndiaye Fatou Samba Diago Ndiaye Moustapha Diop Saliou Department of Haematology Cheikh Anta Diop University Dakar Senegal Department of Neurology Cheikh Anta Diop University Dakar Senegal Internal Medicine Service Aristide Le Dantec Hospital Cheikh Anta Diop University Dakar Senegal

Introduction: Patients with multiple myeloma (MM) develop neurological complications such as root and/or spinal cord compression in at least 5% of cases. The aim of this work is to describe the clinical and radiological features of root and/or spinal cord compression occurring during multiple myeloma. Patients and Methods: We conducted a retrospective study in the Clinical Haematology Department of Dalal Jamm Hospital and the National Blood Transfusion Centre, the Neurological Clinic of Fann Hospital Centre and the Internal Medicine Department of Aristide Le Dantec Hospital in Dakar between January 2016 and December 2019. All patients whose multiple myeloma diagnosis was established according to the International Myeloma Working Group’s 2014 and who had root, spinal or myeloradicular compression, were included in our study. Results: A total of 29 patients were included. The average age was 54.31 years [32 - 76 years]. The sex ratio (M/F) was 1.6. Motor deficits were the reason for consultation in 68% of the patients and spinal pains were reported by 93% of the patients. Neurological signs revealed multiple myeloma in all our patients. 25 patients (86.2%) had paraplegia and 1 patient had tetraparesis. Hypoesthesia to a defined sensory level was noted in 8 patients (28%). 5 patients (17.24%) had sphincter disorders. The types of lesions showed by imaging were vertebral lysis in 100% of cases, vertebral compression in 37% of cases, and epidural infiltration in 34% of cases. 12 patients (41.37%) had spinal compression, 14 patients (48.27%) had

关键词： Multiple Myeloma Spinal Cord Compression Root Compression Bone Lesions