Calcific Uremic Arteriolopathy or Calciphylaxis in a Hemodialysis Patient: Case Study and Review of the Literature
Calcific Uremic Arteriolopathy or Calciphylaxis in a Hemodialysis Patient: Case Study and Review of the Literature作者机构：Department of Nephrology Dialysis and Kidney Transplantation of Aristide Le Dantec Hospital Dakar Senegal Department of Nephrology Dialysis of Louis Pasteur Hospital Chartres France Department of Nephrology Dialysis of Ouakam Military Hospital Dakar Senegal
出 版 物：《Open Journal of Nephrology》 (肾脏病（英文）)
年 卷 期：2022年第12卷第3期
页 面：303-310页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Calcific Uremic Arteriolopathy Calciphylaxis Hemodialysis
摘 要：Calcific uremic arteriolopathy (CUA) is a rare pathology affecting 5% of dialysis patients but with a poor prognosis. It is characterized by calcification and thrombotic lesions of the microcirculation leading to hyperalgesic ischemic skin lesions. Several risk factors have been identified, mainly warfarin treatment, mineral and bone disorders (MBD), inflammation and malnutrition. In the evocative forms, the diagnosis is made based upon the physical examination finding of classic painful ulcerated lesions that are covered by a black eschar. Skin biopsy, due to the risk of aggravation and delayed healing, is only performed in case of doubt diagnosis. The therapeutic attitude due to the lack of solid randomized studies is based on expert consensus and requires a multidisciplinary approach. We report here the case of a patient with CUA revealed in the form of multiple ulcerative-necrotic skin lesions associated with pressure sores and arterial wounds.
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