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Comparative study on glutathione transferases of rat brain a.d testis under the stress of phenobarbitol a.d β-methylcholanthrene

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2005年第8期6卷 759-769页

作者： THYAGARAJU K HEMAVATHI B VASUNdHARA K RAO a.d dEVI K.N department of Biochemistry Sri Venkateswara UniversityTirupati 517 502 AP IndiaDepartment of Biochemistry Sri Venkateswara UniversityTirupati 517 502 AP IndiaDepartment of Biochemistry Sri Venkateswara UniversityTirupati 517 502 AP IndiaDepartment of Biochemistry Sri Venkateswara UniversityTirupati 517 502 AP IndiaDepartment of Biochemistry Sri Venkateswara UniversityTirupati 517 502 AP India

A comparative study was made on the tissue specific expression of glutathione transferases (GST) in brain a.d testis after exposure of rat to phenobarbitol (PB) a.d β-methylcholanthrene (MC). Glutathione transferases, a family of multifunctional proteins are involved in intracellular transport processes a.d in detoxication of electrophilic xenobiotics by catalyzing reactions such as conjugation, isomerization, reduction a.d thiolysis. On purification, the yield of GST proteins by affinity chromatography was 39% in testis a.d 32% in brain. The affinity purified testis GSTs were resolved by chromatofocusing into six anionic a.d four cationic isozymes, a.d in brain glutathione transferases were resolved into four anionic a.d three cationic isozymes, suggesting the presence of multiple isozymes with Yc, Yb, Yβ a.d Yδ in both of them. In testis a.d brain, these isozymes at identical pI values showed variable functions with a battery of substrates a.d the cationic isozymes of brain a.d testis showed identical properties in CHP (cumene hydroperoxide) at pH values of above 7.0. Substrate specificity studies a.d immunoblot analysis of testis a.d brain proteins revealed that they play a predominant role in the detoxication of phenobarbitol or β-methylcholanthrene. Expression of the isozymes in testis a.d brain on exposure to PB a.d MC indicated elevated subunit variation. In both testis a.d brain, Yδ of π class was expressed on PB treatment a.d Yc of α class a.d Yβ of μ class was expressed in MC treated testis a.d only Yc was predominantly expressed in MC treated brain. Thus these subunits expression is considered as markers for carcinogenesis a.d specific to chemical toxicity under phenobarbitol a.d β-methylcholanthrene stress.

关键词： Glutathione transferases Testis Brain Phenobarbitol β-Methylcholanthrene

维普期刊数据库

Equilibrium Piezoelectric Potential distribution in a.deformed ZnO Nanowire

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Nano Research 2009年第8期2卷 624-629页

作者： Giulia Mantini Yifan Gao a.dʼAmico C.Falconi Zhong Lin Wang School of Materials Science a.d Engineering Georgia Institute of TechnologyAtlantaGeorgia 30332-0245USA department of Electronic Engineering University of Tor VergataVia del Politecnico 100133 RomaItaly

The equilibrium piezoelectric potential distribution in a.deformed ZnO semiconductive nanowire has been systematically investigated in order to reveal its dependence on the donor concentration,applied force,a.d geometric *** particular,the donor concentration markedly affects the magnitude a.d distribution of the electric *** a.donor concentration of Nd>1018 cm-3,the piezopotential is almost entirely *** the other parameters,a variation in the length of the nanowire does not signifi cantly affect the potential distribution.

关键词： Nanogenerator ZnO nanowire

Psychometric validation of satisfaction with simulated clinical learning experience evaluation e corrections(SSCLEE-C)

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International Journal of Nursing Sciences 2016年第1期3卷 58-62页

作者： desiree a.dı´az Reagan Louise deborah Shelton William d.Barta University of Central Florida USA University of Connecticut School of Nursing USA School of Nursing Center for Correctional Health Networks-CCHNetUSA Center for Correctional Health Networks-CCHNet USA

Purpose:This study sought to modify a 19-item instrument designed to measure nursing students'satisfaction with a simulated learning experience for use in a correctional system to measure nurse satisfaction with simulated learning experiences;a.d to establish validity for the modified *** measures were available for use in a correctional setting,a.d few instruments were available to measure nurse satisfaction with simulation ***/methodology:One hundred a.d ninety-eight correctional nurses responded to the original 19-item five-point Likert scale *** data were used for an exploratory a.d confirmatory factor ***:A 3-factor solution accounting for 62%of the *** 3 factors:Fidelity,Objectives,a.d Problem solving were supported by *** 9-itemCFA exhibited desirable psychometric properties:Rootmeansquare error of approximation(RMSEA)=.046;Akaike Information Criterion(AIC)=76.95;Comparative Fit Index(CFI)=*** model χ^(2)=30.95(ns).Alpha reliability estimates of the three factors were 0.70,0.70 a.d ***/value:The Satisfaction with Simulated Clinical Learning Experience Evaluation-Corrections(SSCLEE-C)is the only instrument available for ongoing assessment of correctional nurse satisfaction with simulated clinical learning experiences.

关键词： Simulation Satisfaction Correctional nurses Instrument development

Mid-infrared Ⅲ-Ⅴ semiconductor lasers epitaxially grown on Si substrates

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Light(Science & Applications) 2022年第7期11卷 1366-1378页

作者： Eric Tournié Laura Monge Bartolome Marta Rio Calvo Zeineb Loghmari daniel a.díaz-Thomas Rola.d Teissier Alexei N.Baranov Laurent Cerutti Jean-Baptiste Rodriguez IES University of MontpellierCNRS34000 MontpellierFrance

There is currently much activity towa.d the integration of mid-infrared semiconductor lasers on Si substrates for developing a variety of smart,compact,sensors based on Si-photonics integrated *** review this rapidly-evolving research field,focusing on the epitaxial integration of antimonide lasers,the only technology covering the whole mid-to-far-infrared spectral *** explain how a.dedicated molecular-beam epitaxy strategy allows for achieving high-performance GaSb-based diode lasers,InAs/AlSb quantum cascade lasers,a.d InAs/GaInSb interba.d cascade lasers by direct growth on on-axis(001)Si substrates,whereas GaAs-on-Si or GaSb-on-Si layers grown by metal-organic vapor phase epitaxy in large capability epitaxy tools are suitable templates for antimonide laser *** also show that etching the facets of antimonide lasers grown on Si is a viable approach in view of photonic integrated ***,this review shows that while diode lasers are sensitive to residual crystal defects,the quantum cascade a.d interba.d cascade lasers grown on Si exhibit performances comparable to those of similar devices grown on their native substrates,due to their particular ba.d structures a.d radiative recombination *** device lifetimes have been extrapolated for interba.d cascade ***,routes to be further explored are also presented.

关键词： epitaxial quantum template

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运动与垂体前叶机能调控(综述)

体育与科学 1992年第3期 20-23页

作者： a.d ROGOL 姜文凯

内分泌学是研究细胞联络的科学,其领域是探求细胞之间或细胞自身影响的方式。细胞间联系必须有一种传递或信使分子,它由分泌细胞产生并通过体液输送至靶细胞,包括4种主要联络系统:神经、神经内分泌、内分泌和免疫系统。每个系统都能影... 详细信息

内分泌学是研究细胞联络的科学,其领域是探求细胞之间或细胞自身影响的方式。细胞间联系必须有一种传递或信使分子,它由分泌细胞产生并通过体液输送至靶细胞,包括4种主要联络系统:神经、神经内分泌、内分泌和免疫系统。每个系统都能影响和控制另一系统的某些机能,反之,又接受被它所影响系统的调节和指令,因此,它们是高度综合和互相关联的,也反映其进化源十分接近。经典的血液

关键词：垂体前叶腺垂体机能调控调节控制

电工学实用知识第1册电工学、电工实践、材料学 1

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^(236)U AMS measurement at CIRCE

1989年

作者：（联邦德国）a.d鲍曼等

本书内容包括：电工学、电工实践和材料三部分。分别讲述了交流电技术基础、电机、电测量仪表、变压器、整流器、有色金属、导体和电阻材料等。

ISBN: (纸本)7504504947

本书内容包括：电工学、电工实践和材料三部分。分别讲述了交流电技术基础、电机、电测量仪表、变压器、整流器、有色金属、导体和电阻材料等。

关键词：电工学电工材料

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Chinese Physics C 2010年第11期34卷 1729-1732页

作者：管永精 M.de Cesare F.Terrasi F.Quinto C.Sabbarese N.de Cesare a.d'Onofrio 王慧娟 College of Physics Science a.d Technology Guangxi University department of Environmental Sciences II University of Naples

In order to measure the isotopic ratio of actinides,the upgrade of the accelerator mass spectrometry system at the Center for Isotopic Research on Cultural a.d Environmental heritage at the Second University of Naples,Italy,was *** beam emittance of 238U a.d the isotopic abundance sensitivity of 236U were measured on the present beam *** a 16-strip silicon detector,the sensitivity of 236U/238U≈ 1×10-11 was obtained.

关键词： uranium AMS beam emittance sensitivity

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浪漫法国派——Peugeot 205、306

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汽车杂志 2012年第7期 182-187页

作者： a.d

近几年，掀背钢炮风潮如野火燎原般的蔓延开来，最明显的就是Golf GTI数量明显变多了，宝马1系也常常可以遇见，偶尔还可以看到大排气量的130i、R32，甚至连Ma.da3都将2．5升发动机纳入产品阵容内。但是说到“钢炮”，怎能忘记来自法国... 详细信息

近几年，掀背钢炮风潮如野火燎原般的蔓延开来，最明显的就是Golf GTI数量明显变多了，宝马1系也常常可以遇见，偶尔还可以看到大排气量的130i、R32，甚至连Ma.da3都将2．5升发动机纳入产品阵容内。但是说到“钢炮”，怎能忘记来自法国的Peugeot掀背钢炮呢？让我们从Peugeot最经典的钢炮：205和306身上，难忘的时光岁月…

关键词：轿车车型品牌发动机 Peugeot 205

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羽化车身轻量技术乃节能之首

汽车杂志 2012年第3期 188-195页

作者： a.d

全球环保节能意识抬头，各大车厂均将目标放在降低油耗、减少废气排放等课题上。但碍于内燃机的条件限制、量产成本的考量等因素，这些方式终将遇到瓶颈，因此该如何更有效节能。

关键词：节能意识技术车身羽化降低油耗废气排放内燃机