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Simulating FAS-induced apoptosis by using p systems

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progress in Natural Science:Materials International 2007年第4期17卷 424-431页

作者： Smitha Cheruku Andrei pǎun Francisco J. Romero-Campero Mario J. pérez-Jiménez Oscar H. Ibarra Department of Computer Science/IfM Louisiana Tech UniversityP.O. Box 10348RustonLA 71272USA Department of Computer Science and Artificial Intelligence University of SevilleAvda. Reina Mercedes s/n 41012SevillaSpain Department of Computer Science University of California-Santa BarbaraSanta BarbaraCA 93106USA

In contrast to differential equations, p systems are an unconventional model of computation which takes into consideration the discrete character of the quantity of components and the inherent randomness that exists in biological phenomena. The key feature of p systems is their compartmentalised structure which represents the heterogeneity of the structural organisation of the cells, and where one can take into account the role played by membranes in the functioning of the system, for example signalling at the cell surface, selective uptake of substances from the media, diffusion across different compartments, etc. We show here that p systems can be a reliable tool for Systems Biology and could even outperform in some cases the current simulation techniques based on differential equations. We will also use a strategy based on the well known Gillespie algorithm but running on more than one compartment called Multi-compartmental Gillespie Algorithm.

关键词： FAS-induced apoptosis p systems deterministic waiting times algorithm multi-compartmental Gillespie algorithm.

Weighted residual method for diffraction of plane p-waves in a 2-D elastic half-spaceⅢ:on an almost circular arbitrary-shaped alluvial valley

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Earthquake Science 2018年第1期31卷 19-34页

作者： Heather p.Brandow Vincent Lee Brandow&Nastar Inc. Rancho Santa MargaritaCA 92688USA Asanti Civil Environmental Engineering University of Southern CaliforniaLos AngelesCA 90089-2531USA

Scattering and diffraction of elastic in-plane p- and SV-waves by a surface topography such as an elastic canyon at the surface of a half-space is a classical problem which has been studied by earthquake engineers and strong motion seismologists for over forty years. The case of out-of- plane SH-waves on the same elastic canyon that is semicircular in shape on the half-space surface is the first such problem that was solved by analytic closed-form solutions over forty years ago by Trifunac. The corresponding case of in-plane p- and SV- waves on the same circular canyon is a much more complicated problem because the in-plane p- and SV- scattered waves have different wave speeds and together they must have zero normal and shear stresses at the half-space surface. It is not until recently in 2014 that analytic solution for such problem is found by Lee and Liu. This paper uses their technique of defining these stress-free scattered waves, which Brandow and Lee previously used to solve the problem of the scattering and diffraction of these in-plane waves on an almost-circular surface canyon that is arbitrary in shape, to the study of the scattering and diffraction of these in-plane waves on an almost circular arbitrary-shaped alluvial valley.

关键词： Scattering Diffraction Alluvial valley Arbitrary shaped Weighted-residues Amplification

Hybrids of gold nanoparticles and oligo(p-phenyleneethynylene)s end-functionalized with alkynylruthenium groups:Outstanding two-photon absorption in the second biological window

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Nano Research 2020年第10期13卷 2755-2762页

作者： Cristóbal Quintana Mahbod Morshedi Jun Du Joseph p.L.Morrall Jan K.Zaręba Marek Samoc Marie p.Cifuentes Mark G.Humphrey I Research School of Chemistry Australian National UnriversityCanberraACT 2601Australia Advanced Materials Engineering and Modelling Group Wroclaw University of Science and TechnologyWroclaw 50370Poland

Oligo(p-phenyleneethynylene)s(OpEs)end-capped with(alkynyl)bis(diphosphine)ruthenium and thiol/thiolate groups stabilize ca.2 nm diameter gold nanoparticles(AuNps).The morphology,elemental composition and stability of the resultant organometallic OpE/AuNp hybrid materials have been defined using a combination of molecular-and nano-material chacterization *** hybrids display long-term stability in solution(more than a month),good solubility in organic solvents,reversible rutheniumcentered oxidation,and transparency beyond 800 nm,and possess very strong nonlinear absorption activity at the first biological window,and unprecedented two-photon absorption activity in the second biological window(σ2 up to 38,000 GM at 1,050 nm).

关键词： gold nanoparticles inorganic materials metal alkynyl complexes nonlinear optics organometallics

JMCB Symposium 2019:The Legend of p53 ***

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Journal of Molecular Cell Biology 2019年第7期11卷 628-629页

作者： ping Zhang Suzanne p.Christen Gareth L.Bond Ludwig Institute for Cancer Research Nuffield Department of MedicineUniversity of OxfordOxford 0X3 7DQUK The Simons Center for Systems Biology Institute for Advanced StudyPrincetonNJ 08540USA

The exciting symposium hosted by Journal of Molecular Cell Biology (JMCB),with the theme 'The Legend of p53 ***',took place in Hangzhou,China on May 10-12,*** symposium provided the opportunity for delegates in the fields of p53 biology,epigenetics,and cancer research to share scientific updates and to bridge the gap between basic scienee and translational *** delegates also enjoyed celebrations ofthe 40th anniversary ofthe discovery of p53,as well as the 50th anniversary ofthe discovery of RNA polymerases.

关键词： symposium JMCB polymerases

Analysis of structural,optical and electrical properties of metal/p-ZnO-based Schottky diode

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Journal of Semiconductors 2017年第10期38卷 56-62页

作者： Lucky Agarwal Shweta Tripathi p.Chakrabarti Department of Electronics & Communication Engineering Motilal Nehru National Institute of Technology Department of Electronics Engineering Indian Institute of Technology(Banaras Hindu University)

A systematic study of the behaviour of pd/p-ZnO thin film Schottky diode has been *** p-type ZnO thin film with improved stability has been grown on n-type Si by doping ZnO with *** measurement confirmed the p-type nature of Cu-doped ZnO thin *** X-ray diffraction spectra of the deposited film revealed polycrystalline nature with preferred growth orientation of （101） of ZnO *** surface morphological study demonstrated the conformal deposition of a thin film over n-Si *** estimated bandgap of Cu-doped ptype ZnO thin film from ellipsometric measurement turns out to be 3.14 eV at 300 *** measured electrical parameters of the proposed pd/p-ZnO Schottky diode have also been validated by the results of numerical simulation obtained by using ATLAS^（TM） device simulator.

关键词： p-type ZnO Cu-doped ZnO sol-gel method Schottky diode

Changes in Lipid profiles and ^(32)p-Uptake Into phosphoprotein (Vitellogenin) Content of the Ovary and Liver in the Female Catfish, Clarias batrachus,Exposed to Mercury

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Biomedical and Environmental Sciences 1995年第1期8卷 35-44页

作者： R.KIRUBAGARN K.p.JOY CentreofAdvancedStudyinZoology BanarasHinduUniversityVaranasi－221005India CentreofAdvancedStudyinZo

Toxic effects of selected sublethal concentrations of mercuric chloride (HgCl2, 0.05 mg ·L-1), methylmercuric chloride (CH3HgCl, 0.04 mg·L-1) and Emisan 6 (an organic mcrcurial fungicide, 0.5 mg·L-1) on levels of lipids (total lipids-TL, phospholipids-pL, free cholesterol-FC; esterified cholesterol-EC and free fatty acids-FFA), and uptake of 32p into phosphoprotein fraction of the ovary and liver are reported in Clarias batrachus exposed for 45, 90 and 180 days from February to July (preparatory to spawning phase of the annual reproductive cycle). The TL level decreased significantly only in the ovary of 180-day Hg groups. The ovarian pL and FC levels showed a significant reduction at all durations of Hg exposure. In contrast, the hepatic pL and FC levels increased significantly at all durations except the pL content in the 45-day Emisan 6 and CH3HgCl groups. The EC level in the ovary showed a significant decline after both 90 and 180 days of Hg treatment whereas in the liver, it decreased significantly only after 180 days. The level of FFA in the ovary decreased significantly only in the 180-day HgCl2 group while in the liver, it showed a significant increase in all the 180-day Hg groups. The rate and level of incorporation of 32p into phosphoprotein fraction of the ovary and liver showed a progressive decline in the Hg-treated groups, the effect being significantly different only after 90 and 180 days. The results suggest that the decrease in ovarian lipid levels is lareely due to their immobilization from the liver and the reduction in vitellogenin content may be due to both the inhibition of its synthesis in the liver and subsequent incorporation into the ovary.

关键词： Vitellogenin Content of the Ovary and Liver in the Female Catfish Hg In Clarias batrachus,Exposed to Mercury Changes in Lipid profiles and

Influence of temperature on tunneling-enhanced recombination in Si based p–i–n photodiodes

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Journal of Semiconductors 2014年第8期35卷 10-14页

作者： p.Dalapati N.B.Manik A.N.Basu Condensed Matter physics Research Center Department of Physics Jadavpur University

We investigate the dominant dark current transport mechanism in Si based p-i-n photodiodes, namely, BpW 21R, SFH 205FA and BpX 61 photodiodes in the temperature range of 350 to 139 K. The forward current- voltage characteristics of these photodiodes are explained via the tunneling enhanced recombination model, which gives a quantitative description of the electronic mechanism in the p-i-n junction photodiodes. The observed tem- perature dependence of the saturation current and the diode ideality factor of these devices agree well with theo- retical predictions; the analysis also indicates the importance of doping for enhancement of tunneling. The present study will be helpful in applying the devices at low temperature ambience.

关键词： photodiode low temperature ideality factor reverse saturation current tunneling energy

Microbial Biomass C,N and p in Disturbed Dry Tropical Forest Soils,India

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pedosphere 2010年第6期20卷 780-788页

作者： J.S.SINGH D.p.SINGH A.K.KASHYAp Department of Environmental Science Babasaheb Bhimrao Ambedkar University Department of Botany Banaras Hindu University

Variations in microbial biomass C (MB-C),N (MB-N) and p (MB-p) along a gradient of different dominant vegeta- tion covers (natural forest,mixed deciduous forest,disturbed savanna and grassland ecosystems) in dry tropical soils of Vindhyan plateau,India were studied from January 2005 to December *** water holding capacity,organic C,total N,total p and soil moisture content were comparatively higher in forest soils than in the savanna and grassland *** different study sites the mean annual MB-C,MB-N and MB-p at 0-15 cm soil depth varied from 312.05 ± 4.22 to 653.40 ± 3.17,32.16 ± 6.25 to 75.66 ± 7.21 and 18.94 ± 2.94 to 30.83 ± 23.08 μg g ?1 dry soil,*** all the investigated sites,the maximum MB-C,MB-N and MB-p occurred during the dry period (summer season) and the minimum in wet period (rainy season).In the present study,soil MB-C,MB-N and MB-p were higher at the forest sites compared to savanna and grassland *** differences in MB-C,MB-N and MB-p were significant (p p p p (p positively correlated with organic C,while the relationship between soil moisture and MB-C,MB-N and MB-p (p p p pectively) was *** decreasing order of MB-C,MB-N and MB-p along study ecosystems was natural forest > mixed deciduous forest > savanna > *** results suggested that deforestation and land use practices (conversion of forest into savanna and grassland) caused the alterations in soil properties,which as a consequence,led to reduction in soil nutrients and MB-C,MB-N and MB-p in the soil of disturbed sites (grassland and savanna) compared to undisturbed forest ecosystems.

关键词： deciduous forest grassland savanna soil moisture vegetation

Optimisation of laser welding parameters for welding of p92 material using Taguchi based grey relational analysis

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Defence Technology（防务技术） 2016年第4期12卷 343-350页

作者： Shanmugarajan B. Rishabh SHRIVASTAVA Sathiya p. Buvanashekaran G. Welding Research Institute Bharat Heavy Electricals Ltd. Tiruchirappalli 620014 Tamil Nadu India GE India Technology Centre Bangalore India Department of production Engineering NIT Tiruchirappalli India

Creep strength enhanced ferritic(CSEF) steels are used in advanced power plant systems for high temperature applications. p92(Cr–W–Mo–V)steel, classified under CSEF steels, is a candidate material for piping, tubing, etc., in ultra-super critical and advanced ultra-super critical boiler applications. In the present work, laser welding process has been optimised for p92 material by using Taguchi based grey relational analysis(GRA).Bead on plate(BOp) trials were carried out using a 3.5 k W diffusion cooled slab CO_2 laser by varying laser power, welding speed and focal position. The optimum parameters have been derived by considering the responses such as depth of penetration, weld width and heat affected zone(HAZ) width. Analysis of variance(ANOVA) has been used to analyse the effect of different parameters on the responses. Based on ANOVA, laser power of 3 k W, welding speed of 1 m/min and focal plane at-4 mm have evolved as optimised set of parameters. The responses of the optimised parameters obtained using the GRA have been verified experimentally and found to closely correlate with the predicted value.? 2016 China Ordnance Society. production and hosting by Elsevier B.V. All rights reserved.

关键词： Laser Welding Optimisation Taguchi p92