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Nano Research 2011年第4期4卷 360-369页

作者： Ming-Chung Wu Andras Sapi Anna Avila Maria Szabo Jussi Hiltunen Mika Huuhtanen Geza Toth Akos Kukovecz zoltan konya Riitta Keiski Wei-Fang Su Heli Jantunen Krisztian Kordas Department of Electrical and Information Engineering University of Oulu P.O. Box 4500 FI-90014 University of Oulu Finland Department of Applied and Environmental Chemistry University of Szeged 6720 Szeged Rerrich Bela ter 1 Hungary Department of Process and Environmental Engineering P.O. Box 4300 F1-90014 University of Oulu Finland Department of Materials Science and Engineering National Taiwan University Taipei 106-17 Taiwan China

与磅和 Pd nanoparticles 装饰的 TiO2 nanofibers 在各种各样的 photocatalytic 过程被综合了并且学习。在水里的器官的染料的分解的优秀 photocatalytic 行为，灵活独立纤维素 / 催化剂的表面上的器官的污点的降级合成电影并且在从乙... 详细信息

与磅和 Pd nanoparticles 装饰的 TiO2 nanofibers 在各种各样的 photocatalytic 过程被综合了并且学习。在水里的器官的染料的分解的优秀 photocatalytic 行为，灵活独立纤维素 / 催化剂的表面上的器官的污点的降级合成电影并且在从乙醇用的氢的产生推迟了并且使不能调动催化剂被表明。基于 nanofiber 的 TiO2 材料的表演是在某情况 outperformstheir 的竞争 withand 常规基于 nanoparticle 的对应物。在所有情况中，装饰 Pd 的 TiO2 nanoparticles 和 nanofibers 证明了比他们的基于磅的对应物更有效，它能在在 TiO2 和金属 nanoparticles 之间的接触根据缩放 nano 的 Schottky 接口的形成被解释。形成纤维素 / 催化剂 composites 的可行性提供在大区域的涂层和独立电影利用光催化剂材料的一个新奇方法。

关键词： TiO2纳米纳米纤维有机染料复合薄膜光催化活性二氧化钛纳米粒子乙醇分解

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57万亿电动车市场引爆

商业周刊（中文版） 2024年第1期 42-47页

作者： Malcolm Scott Amy Stillman zoltan Simon Patpicha Tanakasempipat Paul Burkhardt Jacob Lorinc 许诺(译) 不详

长达一个世纪的内燃机汽车时代在迈向电动车时代,这一历史性转变正在世界经济的某些令人意想不到的角落制造引爆点。而且现在才刚刚开始。在自然资源丰富的加拿大“火环地带”,由于对环境退化的担忧,电动汽车生产所需矿物的开采许可审... 详细信息

长达一个世纪的内燃机汽车时代在迈向电动车时代,这一历史性转变正在世界经济的某些令人意想不到的角落制造引爆点。而且现在才刚刚开始。在自然资源丰富的加拿大“火环地带”,由于对环境退化的担忧,电动汽车生产所需矿物的开采许可审批速度放缓,不同的环保目标之间在发生冲突。

关键词：内燃机汽车环境退化电动汽车自然资源历史性转变引爆点电动车加拿大

Ranking parameters in urban energy models for various building forms and climates using sensitivity analysis

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建筑模拟(英文) 2023年第9期16卷 1587-1600页

作者： Aysegul Demir Dilsiz Kaitlynn Ng Jérôme Kämpf zoltan Nagy Department of Civil and Architectural Engineering and Construction Management University of WyomingLaramie WYUSA Intelligent Environments Lab Department of CivilArchitectural and Environmental EngineeringThe University of Texas at AustinAustin TXUSA Energy Informatics Group Idiap Research Institute1920 MartignySwitzerland

Urban Building Energy Modelling(UBEM)allows us to simulate buildings’energy performances at a larger ***,creating a reliable urban-scale energy model of new or existing urban areas can be difficult since the model requires overly detailed input data,which is not necessarily publicly *** calibration is a necessary step to reduce the uncertainties and simulation results in order to develop a reliable and accurate *** to the concerns over computational resources and the time needed for calibration,a sensitivity analysis is often required to identify the key parameters with the most substantial impact before the calibration is deployed in ***,we study the sensitivity of uncertain input parameters that affect the annual heating and cooling energy demand by employing an urban-scale energy model,*** goal is to determine the relative influence of each set of input parameters and their interactions on heating and cooling loads for various building forms under different ***,we conduct a global sensitivity analysis for annual cooling and heating consumption under different climate *** upon this,we investigate the changes in input sensitivity to different building forms,focusing on the indices with the largest Total-order ***,we determine First-order indices and Total-order effects of each input parameter included in the urban building energy *** also provide tables,showing the important parameters on the annual cooling and heating demand for each climate and each building *** find that if the desired calibration process require to decrease the number of the inputs to save the computational time and cost,calibrating 5 parameters;temperature set-point,infiltration rate,floor U-value,*** U-value and roof U-value would impact the results over 55%for any climate and any building form.

关键词： global sensitivity analysis Sobol’method urban energy modeling building stocks energy modelling parameter screening Sobol’indices sustainable urban planning

Real-world challenges for multi-agent reinforcement learning ingrid-interactive buildings

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能源与人工智能(英文) 2022年第4期10卷 161-170页

作者： Kingsley Nweye Bo Liu Peter Stone zoltan Nagy Intelligent Environments Laboratory Department of CivilArchitectural and Environmental EngineeringThe University of Texas at Austin301 E.Dean Keeton St.ECJ 4.200Austin78712-1700TXUSA Department of Computer Science The University of Texas at Austin2317 SpeedwayGDC 2.302Austin78712-1700TXUSA

Building upon prior research that highlighted the need for standardizing environments for building controlresearch, and inspired by recently introduced challenges for real life reinforcement learning (RL) control, herewe propose a non-exhaustive set of nine real world challenges for RL control in grid-interactive buildings(GIBs). We argue that research in this area should be expressed in this framework in addition to providing astandardized environment for repeatability. Advanced controllers such as model predictive control (MPC) andRL control have both advantages and disadvantages that prevent them from being implemented in real worldproblems. Comparisons between the two are rare, and often biased. By focusing on the challenges, we caninvestigate the performance of the controllers under a variety of situations and generate a fair comparison.

关键词： Grid-interactive buildings Benchmarking Reinforcement learning

Negative weights in network time model

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Frontiers of Engineering Management 2022年第2期9卷 268-280页

作者： zoltan A.VATTAI Levente MALYUSZ Faculty of Architecture Budapest University of Technology and EconomicsMuegyetem rkp.3H-llll BudapestHungary

Time does not go backward.A negative duration,such as“time period”at first sight is difficult to *** network techniques(CPM/PERT/PDM)did not support negative parameters and/or loops(potentially necessitating recursive calculations)in the model because of the limited computing and data storage capabilities of early *** Roy and John Fondahl implicitly introduced negative weights into network techniques to represent activities with fixed or estimated durations(MPM/PDM).Subsequently,the introduction of negative lead and/or lag times by software developers(IBM)apparently overcome the limitation of not allowing negative time parameters in time *** to general digraph(Event on Node)representation where activities are represented by pairs of nodes and pairwise relative time restrictions are represented by weighted arrows,we can release most restraints in constructing the graph structure(incorporating the dynamic model of the inner logic of time plan),and a surprisingly flexible and handy network model can be developed that provides all the advantages of the above-mentioned *** paper aims to review the theoretical possibilities and technical interpretations(and use)of negative weights in network time models and discuss approximately 20 types of time-based restrictions among the activities of construction *** focus on pure relative time models,without considering other restrictions(such as calendar data,time-cost trade-off,resource allocation or other constraints).

关键词： graph technique network technique construction management scheduling

Longitudinal changes in personalized platelet count metrics are good indicators of initial 3-year outcome in colorectal cancer

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World Journal of Clinical Cases 2022年第20期10卷 6825-6844页

作者： zoltan Herold Magdolna Herold Julia Lohinszky Attila Marcell Szasz Magdolna Dank Aniko Somogyi Division of Oncology Department of Internal Medicine and OncologySemmelweis UniversityBudapest 1083Hungary Department of Internal Medicine and Hematology Semmelweis UniversityBudapest 1088Hungary

BACKGROUND Platelet count or complete blood count(CBC)-based ratios including lymphocyteto-monocyte(LMR),neutrophil-to-lymphocyte(NLR),hemoglobin-to-platelet(HPR),red blood cell count distribution width-to-platelet(RPR),and platelet-tolymphocyte(PLR)ratio are good predictors of colorectal cancer(CRC)*** change in time is not well documented,*** To investigate the effect of longitudinal CBC ratio changes on CRC survival and their possible associations with clinicopathological properties,comorbidities,and anamnestic *** A retrospective longitudinal observational study was conducted with the inclusion of 835 CRC patients,who attended at Semmelweis University,*** ratios and two additional newly defined personalized platelet count metrics(pPLT_(D)and pPLT_(S),the platelet counts relative to the measurement at the time of CRC diagnosis and to the one 4-6 wk after tumor removal surgery,respectively)were *** The 835 CRC patients had a total of 4608 measurements(5.52 visits/patient,in average).Longitudinal survival models revealed that the increases/decreases in LMR[hazard ratio(HR):0.4989,P<0.0001],NLR(HR:1.0819,P<0.0001),HPR(HR:0.0533,P=0.0038),pPLT_(D)(HR:4.9229,P<0.0001),and pPLT_(S)(HR:4.7568,P<0.0001)values were poor prognostic signs of disease-specific *** same was obtained for all-cause *** abnormal changes occurred within the first 3 years after the diagnosis of *** and PLR had an only marginal effect on diseasespecific(P=0.0675)and all-cause mortality(Bayesian 95%credible interval:0.90–186.05),*** LMR,NLR,and HPR are good metrics to follow the prognosis of the ***_(D)and pPLT_(S)perform just as well as the former,while the use of RPR and PLR with the course of the disease is not *** detection of the abnormal changes in pPLT_(D),pPLT_(S),LMR,NLR,or HPR may alert the practicing oncologist for further therapy decisions in a timely manner.

关键词： Personalized platelet count Lymphocyte-to-monocyte ratio Neutrophil-to-lymphocyte ratio Hemoglobin-to-platelet ratio Platelet-to-lymphocyte ratio Colorectal neoplasms

New therapeutic approaches for type 1 diabetes:Disease-modifying therapies

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World Journal of Diabetes 2022年第10期13卷 835-850页

作者： Geza Nagy Tekla Evelin Szekely Aniko Somogyi Magdolna Herold zoltan Herold Department of Internal Medicine and Hematology Semmelweis UniversityBudapest H-1088Hungary Division of Oncology Department of Internal Medicine and OncologySemmelweis UniversityBudapest H-1083Hungary

It has been 100 years since the first successful clinical use of insulin, yet it remains the only treatment option for type 1 diabetes mellitus(T1DM) patients. Advances in diabetes care, such as insulin analogue therapies and new devices, including continuous glucose monitoring with continuous subcutaneous insulin infusion have improved the quality of life of patients but have no impact on the pathogenesis of the disease. They do not eliminate long-term complications and require several lifestyle sacrifices. A more ideal future therapy for T1DM, instead of supplementing the insufficient hormone production(a consequence of β-cell destruction), would also aim to stop or slow down the destructive autoimmune process. The discovery of the autoimmune nature of type 1 diabetes mellitus has presented several targets by which disease progression may be altered. The goal of disease-modifying therapies is to target autoimmune mechanisms and prevent β-cell destruction. T1DM patients with better β-cell function have better glycemic control, reduced incidence of long-term complications and hypoglycemic episodes. Unfortunately, at the time symptomatic T1DM is diagnosed, most of the insulin secreting β cells are usually lost. Therefore, to maximize the salvageable β-cell mass by disease-modifying therapies, detecting autoimmune markers in an early, optimally presymptomatic phase of T1DM is of great importance. Diseasemodifying therapies, such as immuno-and regenerative therapies are expected to take a relevant place in diabetology. The aim of this article was to provide a brief insight into the pathogenesis and course of T1DM and present the current state of disease-modifying therapeutic interventions that may impact future diabetes treatment.

关键词： Type 1 diabetes Mesenchymal stem cell Immunotherapy Islet cells Autoimmunity Regenerative medicine

High plasma CD40 ligand level is associated with more advanced stages and worse prognosis in colorectal cancer

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World Journal of Clinical Cases 2022年第13期10卷 4084-4096页

作者： zoltan Herold Magdolna Herold Gyorgy Herczeg Agnes Fodor Attila Marcell Szasz Magdolna Dank Aniko Somogyi Division of Oncology Department of Internal Medicine and OncologySemmelweis UniversityBudapest H-1083Hungary Department of Internal Medicine and Hematology Semmelweis UniversityBudapest H-1088Hungar Department of General Surgery Szent Imre University Teaching HospitalBudapest H-1115Hungary

BACKGROUND Colorectal cancer(CRC)is often associated with elevated platelet count(>400×10^(9)/L),known as *** role of CD40 ligand(CD40L),a member of the tumor necrosis factor family,is controversial in *** CD40L is higher in CRC,but its relationship with disease staging and local and distant metastasis is not *** most of the circulating CD40L is produced by platelets,no previous study investigated its relationship with CRC-related *** To investigate the role of CD40L to predict the outcome of CRC and its relation to *** A total of 106 CRC patients and 50 age and sex-matched control subjects were enrolled for the *** data including comorbidities and histopathological data were *** measurements were performed at the time of CRC diagnosis and 1.5 mo and at least 6 mo after the surgical removal of the *** CD40L and thrombopoietin were measured via enzyme-linked immunosorbent assay,while plasma interleukin-6 was measured via electrochemiluminescence *** follow-ups were terminated on January 31,*** Plasma CD40L of CRC patients was tendentiously higher,while platelet count(P=0.0479),interleukin-6(P=0.0002),and thrombopoietin(P=0.0024)levels were significantly higher as opposed to the control *** of the 106 CRC patients(11.3%)had *** higher CD40L was found in the presence of distant metastases(P=0.0055)and/or thrombocytosis(P=0.0294).A connection was found between CD40L and platelet count(P=0.0045),interleukin-6(P=0.0130),and thrombocytosis(P=0.0155).CD40L was constant with the course of CRC,and all baseline differences persisted throughout the whole *** pre-and postoperative elevated platelet count,CD40L,and interleukin-6 level were associated with poor overall and disease-specific survival of *** negative effect of CD40L and interleukin-6 on patient survival remained even after the stra

关键词： CD40 ligand Colorectal neoplasms Interleukin-6 Thrombocytosis Thrombopoietin

Long term sediment transport simulation of the Danube,Sava,and Tisa rivers

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International Journal of Sediment Research 2020年第5期35卷 550-561页

作者： Mirjana Horvat zoltan Horvat University of Novi Sad Faculty of Civil Engineering Subotica

The aim of this paper is to evaluate a newly developed one dimensional unsteady flow,sediment transport and bed evolution model for a looped river network through a long term simulation of a reallife *** model was assessed by verifying it for the Danube,Tisa,and Sava rivers in Serbia for a five year time *** total length of the modeled domain was 741.94 km from which 486.48 km is the length of the modeled Danube River reach,132.50 km the modeled section of the Sava and 122.96 km the length of the modeled Tisa River *** simulated domain included smaller tributaries such as the Kolubara,Mlava,Nera,Pek,Porecka,Tamis,and Great Morava *** to the size of the domain that was included in the model,the work also includes extensive research regarding the available measurements,issues with measurement errors,and suggestions on overcoming incomplete measurements by developing different types of *** attained results were analyzed by comparing the simulation results with measured water levels,discharges,and suspended sediment *** implemented evaluation of the results confirmed the developed model's reliability.

关键词： 1-D sediment transport Looped river network Long term simulation Calibration Verification

Computational fluid dynamic(CFD)simulation of pilot operated intermittent gas lift valve

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Petroleum Research 2020年第3期5卷 254-264页

作者： Nagham Amer Sami zoltan Turzo Petroleum and Natural Gas Institute Faculty of Earth Science and EngineeringUniversity of Miskolc3515MiskolcHungary

To design an efficient intermittent gas-lift installation,reliable information is needed in the performance of all process components,from the outer boundary of the reservoir to the surface *** gas lift valve is the one critical component that affects the design of the whole *** intermittent producing system,the pilot gas-lift valve is extremely used to control the point of compressed gas entry into the production tubing and acts as a pressure regulator.A novel approach using computational fluid dynamics simulation was performed in this study to develop a dynamic model for the gas passage performance of a 1-in.,Nitrogen-charged,pilot gas-lift *** performance curves were obtained by using Methane as an injection gas with flow rates reaching up to 4.5 MMscf/*** study investigates the effect of internal pressure,velocity and temperature distribution within the pilot valve that cannot be predicted in the experiments and mathematical models during the flow-performance studies.A general equation of the nonconstant discharge coefficient has been developed for 1-inch pilot valve to be used for further calculation in the industry without using CFD *** developed model significantly reduces the complexity of the data required to calculate the discharge coefficient.

关键词： Gas lift Intermittent Pilot valve CFD Discharge coefficient