检索结果-南通市图书馆

基于“预印本+开放评议”的我国学术出版模式探析

在线全文

学校读者我要写书评

暂无评论

中国科技期刊研究 2024年第8期35卷 1057-1065页

作者：方卿李子星丁靖佳武汉大学信息管理学院湖北省武汉市430072

【目的】为满足科学共同体对科学研究公开、透明的需要,尝试探索预印本与开放评议深度融合的学术出版模式。【方法】以学术出版现存问题为逻辑基点,探讨预印本、开放评议与学术出版的关系,并论述预印本与开放评议结合的理论可行性和实... 详细信息

【目的】为满足科学共同体对科学研究公开、透明的需要,尝试探索预印本与开放评议深度融合的学术出版模式。【方法】以学术出版现存问题为逻辑基点,探讨预印本、开放评议与学术出版的关系,并论述预印本与开放评议结合的理论可行性和实践可行性。在此基础上提出并概述“预印本+开放评议”模式,围绕出版流程、参与主体、核心特质、功能价值等4个方面阐释该模式的主要内涵与运行机理机制。【结果】结合我国国情提出“预印本+开放评议”模式的实践策略:推动参与主体转变思想观念、循序渐进地公开各项内容、搭建学术期刊与已有预印本平台合作的桥梁、修订完善配套制度规范等。【结论】研究成果能够为我国学术出版模式变革提供借鉴。

关键词：学术出版模式审稿模式同行评议 “预印本+开放评议”模式

Al和Ti含量对激光熔炼Al_(x)NbTi_(y)V轻质高熵合金组织与性能的影响

在线全文

学校读者我要写书评

暂无评论

材料工程 2024年第1期52卷 137-145页

作者：李子兴朱言言程序张言嵩高红卫霍海鑫北京航空航天大学前沿科学技术创新研究院北京100191 北京航空航天大学大型金属构件增材制造国家工程实验室北京100191 北京航空航天大学宁波创新研究院浙江宁波315800 北京航空航天大学材料科学与工程学院北京100191

轻质高熵合金在结构材料轻量化方面显示出巨大的应用价值,激光熔炼和激光增材制造技术因其极端冶金条件,为高熵合金研制提供了新思路。采用激光熔炼技术制备Al_(x)NbTiV(x=0.5~7)和AlNbTi_(y)V(y=1~7)纽扣试样,并对其相结构、显微组织... 详细信息

轻质高熵合金在结构材料轻量化方面显示出巨大的应用价值,激光熔炼和激光增材制造技术因其极端冶金条件,为高熵合金研制提供了新思路。采用激光熔炼技术制备Al_(x)NbTiV(x=0.5~7)和AlNbTi_(y)V(y=1~7)纽扣试样,并对其相结构、显微组织和硬度进行了系统研究。结果表明:Al含量对合金相结构和显微组织有显著影响,Al含量低(x≤2)时,Al_(x)NbTiV合金由BCC单相固溶体组成;Al含量高(2

关键词：激光熔炼高熵合金成分变化显微组织相结构硬度

Investigation on the Thermal Conductivity of 3-Dimensional and 4-Directional Braided Composites

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2007年第4期20卷 327-331页

作者： liu Zhenguo Zhang Haiguo Lu zixing li Diansen Institute of Solid Mechanics Beijing University of Aeronautics and Astronautics Beijing 100083 China

It is vital to choose a factual and reasonable micro-structural model of braided composites for improving the calculating precision of thermal property of 3-D braided composites by finite element method （FEM）. On the basis of new microstructure model of braided composites proposed recently, the model of FEM calculation for thermal conductivity of 3-dimennsional and 4-directional braided composites is set up in this paper. The curves of coefficient of effective thermal conductivity versus fiber volume ratio and interior braiding angle are obtained. Furthermore, comparing the results of FEM with the available experimental data, the reasonability and veracity of calculation are confirmed at the same time.

关键词： 3-dimennsional and 4-directional braided composites thermal conductivity FEM

ROP11 GTPase is a Negative Regulator of Multiple ABA Responses in Arabidopsis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2012年第3期54卷 169-179页

作者： zixing li Jun Kang Ning Sui Dong liu MOE Key Laboratory of Bioinformatics School of Life Sciences Tsinghua University Beijing 100084 China

The phytohormone abscisic acid （ABA） plays crucial roles in plant development and plant responses to environmental stresses. Although ABA receptors and a minimal set of core molecular components have recently been discovered, understanding of the ABA signaling pathway is still far from complete. In this work, we characterized the function of ROP11, a member of the plant-specific ROP small GTPases family, in the ABA signaling process. ROP11 is preferentially expressed in guard cells in all plant organs with stomata. Expression of a constitutively active ROP11 （CA-ROP11） suppresses ABA-mediated responses, whereas reduced expression of ROP11 or expression of its dominant-negative form （DN-ROP11） causes the opposite phenotypes. The affected ABA-mediated responses by ROP11 include seed germination, seedling growth, stomatal closure, induction of ABA-responsive genes, as well as plant response to drought stress. Furthermore, we showed that ROP11 and its closest-related family member, ROP10, act in parallel in mediating these responses. ABA treatment does not affect ROP11 transcription and protein abundance; however, it causes the accumulation of CA-ROP11 in the nucleus. These results demonstrated that ROP11 is a negative regulator of multiple ABA responses in Arabidopsis.

关键词： ROP11 GTPase ABA responses negative regulator rop10rop1 double mutant Arabidopsis.

在线全文

学校读者我要写书评

暂无评论

重组人尿激酶原的临床应用研究现状

国际外科学杂志 2024年第3期51卷 212-216页

作者：李子兴毅力起高占峰内蒙古医科大学附属医院血管外科呼和浩特010059

重组人尿激酶原(rhPro-UK)已被广泛应用于治疗各种血栓性疾病,其疗效显著且无明显不良反应,在多个新技术领域也得到了广泛的应用。本文重点介绍了rhPro-UK在急性心肌梗死、脑血管疾病、下肢深静脉血栓形成、动脉血栓形成等疾病治疗中的... 详细信息

重组人尿激酶原(rhPro-UK)已被广泛应用于治疗各种血栓性疾病,其疗效显著且无明显不良反应,在多个新技术领域也得到了广泛的应用。本文重点介绍了rhPro-UK在急性心肌梗死、脑血管疾病、下肢深静脉血栓形成、动脉血栓形成等疾病治疗中的应用情况。rhPro-UK在这些疾病中表现出良好的溶栓效果和安全性,尤其是在急性心肌梗死患者中,辅助经皮冠状动脉介入治疗可以显著提高心肌再灌注,改善心功能,且不增加出血风险。针对脑血管病,rhPro-UK可显著改善神经功能缺损程度,安全性也较高。在下肢深静脉血栓形成治疗中,rhPro-UK相较于尿激酶显示出更优的溶栓效果和安全性。对于动脉血栓形成和生物支架方面,rhPro-UK的应用也取得了一定疗效,但还需要更多的研究来证实其有效性和安全性。此外,超声介导的载药溶栓系统在rhPro-UK治疗中也具有潜在的应用前景,对于rhPro-UK未来的研究重点将会更加集中在新技术的开发上。

关键词：血栓溶解疗法血栓栓塞药物洗脱支架声学微泡重组人尿激酶原

在线全文

学校读者我要写书评

暂无评论

激光辐照对竹材抗劈力的影响

家具 2024年第2期45卷 16-19,31页

作者：朱骏杰李子欣王雪花南京林业大学家居与工业设计学院南京210037

竹材内应力大、横向连接弱是造成竹材容易劈裂、影响其使用的重要原因。激光处理热效率高,可调整基体结构,细化晶粒,消除内应力。为研究激光对竹材抗劈力的影响,通过激光辐照毛竹材,分析激光功率、辐照时间、试件厚度及竹材表皮保留情... 详细信息

竹材内应力大、横向连接弱是造成竹材容易劈裂、影响其使用的重要原因。激光处理热效率高,可调整基体结构,细化晶粒,消除内应力。为研究激光对竹材抗劈力的影响,通过激光辐照毛竹材,分析激光功率、辐照时间、试件厚度及竹材表皮保留情况对毛竹抗劈力的影响,结果表明:毛竹抗劈力较低,小于2.5 N/mm;毛竹抗劈力随激光功率的增大而增大,激光功率为2 100 mW时较未处理毛竹的抗劈力提高13.5%;激光辐照处理30 s时较未处理毛竹抗劈力提高13.5%;随辐照时间延长、试件厚度增加,毛竹抗劈力减小;保留竹青有利于提高竹材的抗劈力;激光辐照对竹黄侧抗劈力的提高效果最好,可使其提高20%。

关键词：竹材抗劈力激光功率处理时间表面状况

Removal of Microcystin-LR in lake water sample by hydrophilic mesoporous silica composites under high-throughput MALDI-TOF MS detection platform

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第5期35卷 380-385页

作者： Wantong Zhang zixing Xu Guofei Dai Zhijian li Chunhui Deng Department of Chemistry Institute of Metabolism&Integrate Biology(IMIB)Fudan UniversityShanghai 200433China Jiangxi Key Laboratory of Organic Chemistry Jiangxi Science and Technology Normal UniversityNanchang 330013China Jiangxi Academy of Water Science and Engineering Nanchang 330029China

Microcystins(MCs),a family of cyclic heptapeptide cyanotoxins,exists in aquatic environment where cyanobacterial bloom happens,which will accumulate in aquatic organisms and transfer through the food chain to higher trophic levels,posing a health risk to both animals and human *** various MCs,Microcystin-LR(MC-LR)is worthiest studied for its strong toxicity,ubiquity and *** in this work,iminodiacetic acid(IDA)decorated magnetic mesoporous silica(mSiO_(2))nanocomposites(Fe_(3)O_(4)@mSiO_(2)-IDA)were facilely synthesized which possessed the merits of large surface area(188.21 m^(2)/g),accessible porosity(2.66 nm),excellent hydrophilicity and rapid responsiveness to magnetic *** the composites were successfully employed to the removal process of Microcystin-LR in real water samples followed by Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF MS)analysis,achieving the removal efficiency above 92.5%even after ten recycles of the *** provided a potential method for removing MC-LR in aqueous environment with high effectiveness,lower costs and less secondary contamination.

关键词： Microcystin-LR Mesoporous silica Magnetic composites MALDI-TOF MS analysis

ROP11 GTPase Negatively Regulates ABA Signaling by Protecting ABI1 Phosphatase Activity from Inhibition by the ABA Receptor RCAR1/PYL9 in Arabidopsis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2012年第3期54卷 180-188页

作者： zixing li Zheng li Xiang Gao Viswanathan ChinnusamyI Ray Bressant Zhi-Xin Wang Jian-Kang Zhu Jia-Wei Wu Dong liu MOE Key Laboratory of Bioinformatics School of Life Sciences Tsinghua University Beijing 100084 China Division of Plant Physiology Indian Agricultural Research Institute New Delhi 110012 India Department of Horticulture and Landscape Purdue University West Lafayette Indiana 47907 USA

The phytohormone abscisic acid （ABA） regulates many key processes in plants, such as seed germina- tion, seedling growth, and abiotic stress tolerance. In recent years, a minimal set of core components of a major ABA signaling pathway has been discovered. These components include a RCAR/PYR/PYL family of ABA receptors, a group of PP2C phosphatases, and three SnRK2 kinases. However, how the interactions between the receptors and their targets are regulated by other proteins remains largely unknown. In a companion paper published in this issue, we showed that ROP11, a member of the plant- specific Rho-like small GTPase family, negatively regulates multiple ABA responses in Arabidopsis. The current work demonstrated that the constitutively active ROP11 （CA-ROP11） can modulate the RCAR1/PYL9-mediated ABA signaling pathway based on reconstitution assays in Arabidopsis thaliana protoplasts. Furthermore, using luciferase complementation imaging, yeast two-hybrid assays, co- immunoprecipitation assays in Nicotiana benthamiana and bimolecular fluorescence complementation assays, we demonstrated that CA-ROP11 directly interacts with ABI1, a signaling component downstream of RCAR1/PYL9. Finally, we provided biochemical evidence that CA-ROP11 protects ABI1 phosphatase activity from inhibition by RCAR1/PYL9 and thus negatively regulates ABA signaling in plant cells. A model of how ROP11 acts to negatively regulate ABA signaling is presented.

关键词： ROP11 GTPase ABA signaling RCAR1/PYL9A ABI1 Arabidopsis.

Ruins of the Bronze Age Inscribed on the World Heritage list

在线全文

学校读者我要写书评

暂无评论

China & The World Cultural Exchange 2006年第9期72卷 22-24页

作者： Zhou Wei & li zixing

On July 13, Yin Xu, ruins of ancient Shang Dynasty capital in Anyang City was inscribed on the World Heritage list and became China’s 33rd World Heritage site.

关键词：世界遗产目录商朝首都安阳青铜器中国文化事业考古