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苦瓜种质资源农艺和品质性状遗传多样性分析

中国蔬菜 2024年第3期 104-110页

作者：汪自松李兆佳罗厚仟沈伟王涛涛杨静刘正鲁百色学院农业与食品工程学院广西百色533000 华中农业大学园艺植物生物学教育部重点实验室湖北武汉430070 贵州大学精细化工研究开发中心贵州贵阳550025

以48份苦瓜种质资源为试材,对与果实相关的10个农艺性状和5个品质性状进行变异性和相关性研究,并进行主成分分析和聚类分析。结果表明:农艺性状平均变异系数为33.9%,瓜棱变异系数最大,瓜长最小,变异范围为18.0%~49.6%,表明苦瓜的遗传基... 详细信息

以48份苦瓜种质资源为试材,对与果实相关的10个农艺性状和5个品质性状进行变异性和相关性研究,并进行主成分分析和聚类分析。结果表明:农艺性状平均变异系数为33.9%,瓜棱变异系数最大,瓜长最小,变异范围为18.0%~49.6%,表明苦瓜的遗传基础较宽。相关性分析与主成分分析表明,与果实相关的10个农艺性状间呈极显著相关,农艺性状与品质性状之间的相关性不高,且品质性状之间不存在显著相关关系,表明农艺性状与品质性状的遗传选择相对独立。农艺性状主成分分析中4个主成分累计贡献率为75.51%,单瓜鲜质量与单瓜干质量、瓜上径粗和瓜下径粗呈极显著正相关,表明选育瓜径粗较大的材料有利于配制单瓜鲜质量适中的高产杂交组合。聚类分析在D2=5时,将48份苦瓜材料分为特征不同的三大类,并筛选出早熟材料131-1、2101-2、2116,晚熟材料2106-4,综合性状较好的材料46-1-1、67-1、80-1,以及雌性系168-1,这8份苦瓜种质可作为优异目标亲本选择。

关键词：苦瓜遗传多样性主成分分析聚类分析

Evaluation of abundant hydrocarbon-generation depressions in the deepwater area of Qiongdongnan Basin,South China Sea

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Acta Oceanologica Sinica 2016年第2期35卷 137-144页

作者： LIU Zhen SUN Zhipeng wang zisong ZHANG Wei LI Tingan HE Weijun LI Fengxia CAO Shang LIU Jingjing LIN Lu Key Laboratory of Petroleum Resource and Prospecting China University of Petroleum Beijing 102249 China Zhanjiang Branch of China National Offshore Oil Corporation (CNOOC) Limited Zhanjiang 524057 China Petro China Jidong Oilfield Company Tangshan 063000 China Research Institute of Yanchang Petroleum Group Xi'an 710075 China Shenzhen Branch of China National Offshore Oil Corporation (CNOOC) Limited Guangzhou 510240 China

It has been confirmed that the key source rocks of Qiongdongnan Basin are associated with the Yacheng Formation, which was deposited in a transitional marine-continental environment. Because the distribution and evolution patterns of the source rocks in the major depressions are different, it is important to determine the most abundant hydrocarbon-generation depressions in terms of exploration effectiveness. Based on an analysis of organic matter characteristics of the source rocks, in combination with drilling data and seismic data, this paper establishes a model to evaluate the hydrocarbon-generation depressions in the deepwater area of Qiongdongnan Basin. First of all, by using the method of seismic-facies model analysis, the distribution of sedimentary facies was determined. Then, the sedimentary facies were correlated with the organic facies, and the distribution of organic facies was predicted. Meanwhile, the thickness of source rocks for all the depressions was calculated on the basis of a quantitative analysis of seismic velocity and lithology. The relationship between mudstone porosity and vitrinite reflectance（Ro） was used to predict the maturity of source rocks. Second, using the parameters such as thickness and maturity of source rocks, the quantity and intensity of gas generation for Yacheng and Lingshui Formations were calculated. Finally, in combination with the identified hydrocarbon resources, the quantity and intensity of gas generation were used as a guide to establish an evaluation standard for hydrocarbon-generation depressions, which was optimized for the main depressions in the Central Depression Belt. It is proposed that Lingshui, Ledong, Baodao and Changchang Depressions are the most abundant hydrocarbon depressions, whilst Songnan and Beijiao Depressions are rich hydrocarbon depressions. Such an evaluation procedure is beneficial to the next stage of exploration in the deep-water area of Qiongdongnan Basin.

关键词： comprehensive evaluation hydrocarbon-generation depressions source rocks deepwater area Qiongdongnan Basin

A High-Contrast Autolysosome Probe for Detecting Interaction between Autophagosomes and Autolysosomes in Mitophagy

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Chinese Journal of Chemistry 2024年第8期42卷 858-866页

作者： Weihua wang Chu Han Shengjie Xie zisong Cong Zixuan Yang Yuxin Feng Limin Xiang Heng Song College of Chemistry and Molecular Sciences Wuhan UniversityWuhanHubei430072 China

Comprehensive Summary,Autophagy is a multi-step cell metabolism process in which cells remove damaged and unwanted *** autophagy,autophagosomes fuse with lysosomes to form *** membrane components are recycled from autolysosomes through the autophagosomal components recycling(ACR),while lysosomal components circulate on the autolysosomal surface through the autophagic lysosome reformation(ALR)*** contain components from autophagosomes and ***,whether there is a fusion between autolysosome and autophagosome or lysosome at the organelle level remains *** this study,a pH and viscosity dual-controlled mitochondria-targeting fluorescent probe Mito-Q was designed based on an asymmetric norcyanine to achieve the high-contrast imaging of mitochondria-containing ***-Q not only effectively detected mitochondrial viscosity changes and mitophagy with high sensitivity,but more importantly,the fusion of mitochondria-containing autolysosomes and autophagosomes(FMAA)was observed during autophagy by the real-time confocal imaging of HeLa cells.

关键词： Mitophagy Autolysosomes Bioimaging Biosensors Fluorescence imaging

Qingre Lishi Tuihuang therapy for acute icteric hepatitis B: A systematic review

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Journal of Traditional Chinese Medical Sciences 2017年第2期4卷 95-105页

作者： zisong wang Xueqian wang Jiajie Zhu Fafeng Cheng Haiqiang Yao Zheng Yang Zengliang Zhang Qingguo wang Beijing University of Chinese Medicine Beijing 100029China Department of Gastroenterology Wangjing HospitalChina Academy of Traditional Chinese MedicineBeijing 100102China Traditional Chinese Medicine College Inner Mongolia Medical UniversityHohhot 010110China

Objective:To assess the efficacy of Qingre Lishi Tuihuang therapy (QLTT) for acute icteric hepatitis B ***:Eight electronic databases were searched from inception to December 2016 with no language restrictions for reports of randomized controlled trials evaluating the effect of QLTT treating acute icteric hepatitis *** researchers independently extracted detailed data and assessed methodological *** 5.3.0 software was used to analyze the ***:A total of 13 randomized controlled trials involving 2238 participants were included in this *** methodological quality was generally *** results indicated that supplemented Yinchenhao decoction combined with non-specific treatments was more effective in improving the cure rate (risk ratio =1.80;95% CI 1.21-2.68) and reducing the serum levels of total bilirubin (mean difference =-29.74;95% CI-31.91 to-27.57) and aspartate *** self-made prescriptions conforming to QLTT plus non-specific treatments had beneficial effect for acute icteric hepatitis B in curing this disease (risk ratio =1.48;95% CI 1.27-1.73),as well as for negative seroconversion of HBeAg (risk ratio =1.39;95% CI 1.11-1.74).Supplemented Yinchenhao decoction plus non-specific treatments was more effective than other self-made prescriptions conforming to QLTT in reducing serum total bilirubin ***:Qingre Lishi Tuihuang therapy appears to improve effect based on non-specific treatments for the treatment of acute icteric hepatitis ***,it is premature to draw confirmative conclusions,owing to the poor methodological quality and high clinical heterogeneity of the included *** well-designed clinical randomized controlled trials with large sample sizes should be undertaken.

关键词： Qingre Lishi Tuihuang therapy Acute icteric hepatitis B Systematic review Traditional Chinese medicine

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超压盆地油气垂向运移高度研究

地质学报 2017年第7期91卷 1634-1640页

作者：刘震夏鲁王子嵩张旺中国石油大学油气资源与探测国家重点实验室北京102249 中国石油大学地球科学学院北京102249 中国石油冀东油田公司河北唐山063000 中国科学院地质与地球物理研究所北京100029

在超压盆地中,当断层活动断开超压烃源岩时,油气会沿断层面发生涌流式垂向运移,这一瞬态涌流过程为油气大规模运聚成藏提供了重要的油气来源。然而,对于油气沿断层垂向运移距离问题的研究,停留在定性分析阶段,较少考虑到断层开启时造成... 详细信息

在超压盆地中,当断层活动断开超压烃源岩时,油气会沿断层面发生涌流式垂向运移,这一瞬态涌流过程为油气大规模运聚成藏提供了重要的油气来源。然而,对于油气沿断层垂向运移距离问题的研究,停留在定性分析阶段,较少考虑到断层开启时造成的泄压作用,也很少区分地层水和油气运移距离的差异。本文认为,油气顺断层向上运移的距离主要由源岩超压带内超压幅度决定,油气垂向运移理论高度可由超压幅度折算,因而超压幅度越大,油气垂向运移距离越远,油气上涌顶界面埋深越浅。油气初次上涌的起始位置不是地表面,而是有效烃源岩顶面。另外,由于油气的大量上涌,超压带快速泄压,大部分油气上涌实际距离不能达到理论上涌的最大距离。同时,考虑到沿断层运移时受到阻力作用,油气实际上垂向运移高度远远小于理论运移高度。

关键词：超压断层水头起始位置垂向运移高度

带水平滑移层框架空心砖填充墙的平面外稳定性

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西南交通大学学报 2023年第2期58卷 438-445页

作者：苏启旺杨寒李志黎王自松汪铸航西南交通大学土木工程学院四川成都610031

空心砖填充墙体内设置水平滑移层,能削弱墙充墙的斜撑作用,可有效减轻空心砖填充墙的破坏程度.为研究设置水平滑移层框架空心砖填充墙体的平面外稳定性,分析了填充墙平面外破坏模式,基于设置水平滑移层框架空心砖填充墙的平面内拟静力试... 详细信息

空心砖填充墙体内设置水平滑移层,能削弱墙充墙的斜撑作用,可有效减轻空心砖填充墙的破坏程度.为研究设置水平滑移层框架空心砖填充墙体的平面外稳定性,分析了填充墙平面外破坏模式,基于设置水平滑移层框架空心砖填充墙的平面内拟静力试验,建立设置水平滑移层和未设置水平滑移层的框架空心砖填充墙的有限元模型,开展了平面外数值模拟的对比分析.结果表明:水平滑移层会降低墙体整体性,削弱周边框架对墙体的约束作用;与未设置滑移层的普通填充墙相比,设置水平滑移层的填充墙在平面外荷载作用下的破坏程度增加,平面外位移和刚度退化速率增大,平面外开裂荷载降低43.1%,峰值荷载降低22.2%;设置水平滑移层的填充墙在不同抗震设防烈度的多遇和罕遇地震作用下,墙体平面外承载力大于按规范计算要求的平面外承载力,满足规范要求.

关键词：空心砖填充墙水平滑移层数值模拟平面外稳定性

Efficacy and safety of Yinchenwuling powder for hyperlipidemia: a systematic review and Meta-analysis

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Journal of Traditional Chinese Medicine 2016年第2期36卷 135-143页

作者： Yao Haiqiang Zhang Zengliang wang Ji Zuo Jiacheng Chen Yu Zhu Libing Li Xiaoke Yang Zheng wang zisong Sun Ranran Xu Xuanxuan Li Changming Wu Yanling Li Lingru wang Qi Basic Medi-cal College Beijing University of Chinese Medicine Beijing100029 China Traditional Chinese Medicine College in-ner Mongolia Medical University Hohhot 01011 O China Department of Nutrition Chinese-Japan Friend-ship Hospital Beijing 100029 China

OBJECTIVE:To assess the clinical effectiveness and adverse effects of Yinchenwuling powder(YCWLP)in the treatment of hyperlipidemia using ***:Seven electronic databases were searched for randomized controlled trials designed to evaluate the clinical effectiveness of YCWLP for hyperlipidemia published in any language prior to February *** reviewers independently identified articles,extracted data,assessed quality,and cross-checked the *** 5.3 was used to analyze the ***:Only five randomized controlled trials with poor methodology were included in the *** five trials compared YCWLP with conventional lipid-lowering ***-analysis indicated that YCWLP was more effective at the levels of total cholesterol and triglycerides,while increasing the level of high-density lipoprotein cholesterol without serious adverse ***,it was not more effective than lipid-lowering drugs in reducing low-density lipoprotein cholesterol and improving ***:YCWLP appeared to improve lipid ***,given the high risk of bias among the trials,we could not conclude that YCWLP was beneficial to patients with *** rigorous trials are required to provide stronger evidence for the conclusion.

关键词： Hyperlipidemias Review Meta-analy sis Yinchenwuling powder Randomized controlled trials

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辽东湾断陷油气成藏模式及主控因素

地球科学（中国地质大学学报） 2014年第10期39卷 1407-1420页

作者：杨宝林叶加仁王子嵩薛海琴中国地质大学构造与油气资源教育部重点实验室湖北武汉430074 中国地质大学资源学院湖北武汉430074 中国石油冀东油田公司河北唐山063004 中国地质大学江城学院湖北武汉430200

为深入研究辽东湾断陷油气成藏机理,利用地震、钻井、地化、试油等资料,在分析油气成藏条件与特征的基础上,总结划分了辽东湾断陷的典型油气成藏模式,并对比分析了不同成藏模式的主控因素.研究成果表明:辽东湾断陷具有优越的油气成藏条... 详细信息

为深入研究辽东湾断陷油气成藏机理,利用地震、钻井、地化、试油等资料,在分析油气成藏条件与特征的基础上,总结划分了辽东湾断陷的典型油气成藏模式,并对比分析了不同成藏模式的主控因素.研究成果表明:辽东湾断陷具有优越的油气成藏条件,发育沙三段、沙一段和东三段3套烃源岩系和上、中、下3套储盖组合及多类型输导介质,已发现的油气藏类型以构造型为主;油气纵向上以东二段、潜山和沙一二段最为富集,横向上主要分布在断裂带附近.辽东湾断陷的油气成藏模式可划分为单向单源单一潜山型、单向单一古储型、复合古储型、单向深源复合新储型和自生自储自盖型5大类15个亚类.潜山型油气藏主要分布在辽西低凸起北段和中段,成藏主控因素为流体动力和潜山物性;单一古储型油气藏主要分布在辽西、辽中凹陷的洼陷带和陡坡带,成藏主要受断层控制,烃源岩成熟度控制了油气性质;复合古储型油气藏主要分布在辽西低凸起中北段和辽中凹陷南洼缓坡带,成藏主控因素主要为流体动力和输导通道;新储型油气藏主要分布在辽东湾南部大断层附近,油气富集主要受盖层和新近系断裂活动的共同控制;自生自储自盖油气藏主要分布在生烃洼陷烃源岩内部,主要受储层物性的影响.

关键词：油气成藏特征成藏模式主控因素辽东湾断陷石油地质

大柴胡汤现代文献可视化研究及其临床配伍分析

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中国临床研究 2023年第5期36卷 704-709页

作者：赵世同王梓淞王佳曹锐首都医科大学附属北京朝阳医院中医科北京100020 中国中医科学院针灸研究所北京100700

目的通过对大柴胡汤相关文献及验案进行分析,明确其研究历史、研究现状及临床配伍规律。方法运用文献计量学方法,检索中国知网(CNKI)中1961年至2021年大柴胡汤相关文献,对其发表数量、期刊、病种和药理作用进行统计分析,同时使用CiteSp... 详细信息

目的通过对大柴胡汤相关文献及验案进行分析,明确其研究历史、研究现状及临床配伍规律。方法运用文献计量学方法,检索中国知网(CNKI)中1961年至2021年大柴胡汤相关文献,对其发表数量、期刊、病种和药理作用进行统计分析,同时使用CiteSpace对其进行可视化分析。筛选2011年至2021年大柴胡汤效案,建立标准处方数据库,形成药物共现复杂网络,并进行聚类分析。结果通过检索共纳入文献1898篇,1961年至2021年间相关文献的发表数量总体呈上升趋势,以中医类期刊为主。本方具有抗炎、保肝、利胆、抗动脉粥样硬化和降脂等作用,临床上主要用于急性胰腺炎、胆囊炎及胆石症等的治疗。大柴胡汤及加减方对相关疾病的临床治疗是主要研究重点。此外,大柴胡汤常配伍金钱草、郁金、鸡内金等利胆排石、疏肝止痛之药,而桂枝茯苓丸是其最为常用的合方之一。结论大柴胡汤是临床及科研的热门经方之一,但目前仍缺乏高级别的循证医学证据和机理探讨,亟待学者深入研究。

关键词：大柴胡汤文献可视化分析急性胰腺炎胆囊炎胆石症研究重点配伍规律