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积污对光触发晶闸管换流阀电压监测板的影响及其对策研究

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高压电器 2025年第2期61卷 141-150页

作者：刘子琛王黎明尹芳辉徐永生张福增国网南京供电公司南京210019 清华大学深圳国际研究生院广东深圳518055 南方电网科学研究院有限责任公司广州510080

近年来,特高压直流工程发生多起因晶闸管电压监测板(thyristor voltage monitoring board,TVMB)积污引起的换流阀停运事故。文中针对TVMB故障开展深入研究,介绍了TVMB的工作原理,针对关键模块开展电路分析,探讨了TVMB的失效机理;搭建了T... 详细信息

近年来,特高压直流工程发生多起因晶闸管电压监测板(thyristor voltage monitoring board,TVMB)积污引起的换流阀停运事故。文中针对TVMB故障开展深入研究,介绍了TVMB的工作原理,针对关键模块开展电路分析,探讨了TVMB的失效机理;搭建了TVMB电路模型并开展仿真工作,主要研究了元件参数变化对TVMB功能的影响;搭建了TVMB加压试验平台并对理论和仿真分析结果进行了验证;最后提出了针对TVMB失效故障的防治对策。研究结果表明TVMB长年运行后积污严重,在高湿环境中污层受潮使得均压电阻实际阻值减小,导致回报脉冲信号提前产生;储能电容并联电阻值减小,导致回报脉冲信号无法产生。可恢复性测试结果表明,TVMB失效故障不会造成破坏性损伤,文中据此提出降低阀厅相对湿度、定期开展TVMB清洗工作等防治对策并已在宝安换流站成功应用。

关键词：晶闸管电压监测板表面污秽相对湿度均压电阻储能电容

Bacteriophages in water pollution control:Advantages and limitations

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Frontiers of Environmental Science & Engineering 2021年第5期15卷 29-43页

作者： Mengzhi Ji zichen liu Kaili Sun Zhongfang Li Xiangyu Fan Qiang Li School of Biological Science and Technology University of JinanJinan250022China College of Food and Bioengineering Hezhou UniversityHezhou542899China

Wastewater is a breeding ground for many pathogens,which may pose a threat to human health through various water transmission ***,a simple and effective method is urgently required to monitor and treat *** bacterial viruses,bacteriophages(phages)are the most widely distributed and abundant organisms in the *** to their capacity to specifically infect bacterial hosts,they have recently been used as novel tools in water pollution *** purpose of this review is to summarize and evaluate the roles of phages in monitoring pathogens,tracking pollution sources,treating pathogenic bacteria,infecting bloom-forming cyanobacteria,and controlling bulking sludge and biofilm pollution in wastewater treatment *** also discuss the limitations of phage usage in water pollution control,including phage-mediated horizontal gene transfer,the evolution of bacterial resistance,and phage concentration *** review provides an integrated outlook on the use of phages in water pollution control.

关键词： Phage Water pollution monitoring Harmful bacteria biocontrol Horizontal gene transfer Bacterial resistance

Prophages domesticated by bacteria promote the adaptability of bacterial cells

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BIOCELL 2020年第2期44卷 157-166页

作者： zichen liu YUNFENG DENG MENGZHI JI WENQING SUN XIANGYU FAN College of Biological Science and Technology University of JinanJinan250022China Shandong Provincial Chest Hospital Jinan250013China

Prophages are temperate phages integrated into the host bacterial *** play an important role in the adaptation and the pathogenicity of bacteria,especially pathogenic *** this review,we described the distribution of prophages in different hosts and different environments,and focused on the significance of *** the singlecell level,prophages can help the host adapt to harsh external environments by directly carrying virulence genes,encoding regulatory factors and activating *** the population level,prophages can influence the overall evolutionary direction and ecological function of the host bacterial *** review will help us understand the important role of prophages as unique organisms in individual bacteria and microbial populations.

关键词： Temperate phage Adaptation Evolution Ecological function

Progresses of mycobacteriophage-based Mycobacterium tuberculosis detection

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BIOCELL 2020年第4期44卷 683-694页

作者： zichen liu SIYAO GUO MENGZHI JI KAILI SUN ZHONGFANG LI XIANGYU FAN School of Biological Science and Technology University of JinanJinan250022China Nanyang Technological University Food Technology Centre(NAFTEC) 637459Singapore School of Chemical and Biomedical Engineering Nanyang Technological University637459Singapore College of Food and Bioengineering Hezhou UniversityHezhou542899China

Tuberculosis(TB)remains a major cause of morbidity and mortality worldwide,particularly in developing countries.A rapid and efficient method for TB diagnosis is indispensable to check the trend of tuberculosis *** emergence of drug-resistant bacteria has increased the challenge of rapid drug resistance *** to its high specificity and sensitivity,bacteriophage-based diagnosis is intensively *** this review,we mainly described mycobacteriophage-based diagnosis in TB detection,especially two prevalent approaches:fluorescent reporter phage and phage amplified biologically assay(PhaB).The rationale of reporter phage is that phage carrying fluorescent genes can infect host bacteria *** amplified biological assay based on the principle that phages can infect the live Mycobacterium tuberculosis in the specimen under suitable conditions and produce *** phage-based diagnostic methods,such as a combination of the amplified biologically assay and nucleic acid amplification or lateral flow assays,are also actively *** review will help us improve the understanding of mycobacteriophages in TB detection and better promote the development of the rapid diagnosis of ***.

关键词： Mycobacteriophage Tuberculosis Diagnosis Reporter phage Phage amplified biologically assay

Effect of contamination and relative humidity on the function of thyristor voltage monitoring board

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High Voltage 2022年第6期7卷 1165-1174页

作者： zichen liu Liming Wang Hongwei Mei Bin Cao Fanghui Yin Yongsheng Xu Fuzeng Zhang Yi Jiang Masoud Farzaneh Shenzhen International Graduate School Tsinghua UniversityShenzhenChina Electric Power Research Institute China Southern Power Grid Co.LtdGuangzhouChina Department of Applied Sciences University of Quebec at ChicoutimiChicoutimiQuebecCanada

In recent years,shutdown accidents caused by thyristor voltage monitoring(TVM)board failure have occurred several times in converter *** the increase of operation time,the working reliability problem of TVM board becomes a challenge to the safe *** paper studies the effects of pollution severity and relative humidity(RH)on the function of TVM *** results show that the increase of RH can lead to the advance or even disappearance of check-back ***,the increase of pollution severity can decrease the failure RH *** simulation and equivalent experiment,it is verified that the resistance decrease of the voltage balancing resistor under the combined effect of contamination and RH is the main reason for the advance of check-back *** to the experiments,it is found that the upper surface contamination has a greater effect on the function of TVM board than the lower surface contamination,resulting in more decrease of the failure RH *** addition,leakage current at different RH is also *** show that the pulse peak of leakage current is closely related to check-back *** the pulse peak is too small or disappears,check-back signals also disappear,indicating that the TVM board fails.

关键词： function humidity TVM

肺癌合并非结核分枝杆菌感染的临床病理学特征

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检验医学与临床 2025年第1期22卷 81-85页

作者：林海峰孙祖钰苏丹周立娟刘子臣车南颖首都医科大学附属北京胸科医院病理科北京101149

目的分析肺癌合并非结核分枝杆菌(NTM)感染的临床病理学特征、诊断及鉴别诊断,以提高对肿瘤合并感染的认识及诊断水平。方法回顾性分析2010年1月至2023年12月该院16例肺癌合并NTM感染患者的临床病理特征、免疫表型及分子生物学特征,... 详细信息

目的分析肺癌合并非结核分枝杆菌(NTM)感染的临床病理学特征、诊断及鉴别诊断,以提高对肿瘤合并感染的认识及诊断水平。方法回顾性分析2010年1月至2023年12月该院16例肺癌合并NTM感染患者的临床病理特征、免疫表型及分子生物学特征,并结合文献进行探讨。结果 16例肺癌合并NTM感染的患者临床主要表现为发热、咳嗽咳痰、咯血及胸闷等呼吸系统症状,仅1例无临床症状。有2例患者有吸烟史,3例患者患有潜在的肺部疾病,如双肺多发囊状支气管扩张和肺囊肿。肺癌的组织学类型为常见的鳞状细胞癌5例,腺癌10例(其中5例为原位腺癌或微小浸润性腺癌)及小细胞癌1例;分枝杆菌感染结果显示,感染胞内分枝杆菌5例,龟/脓肿分枝杆菌4例,鸟分枝杆菌3例,蟾蜍分枝杆菌3例及堪萨斯分枝杆菌1例;肿瘤分期为Ⅰ~Ⅱ期12例,Ⅲ期3例。经随访,1例患者因放弃肿瘤治疗出现呼吸衰竭而死亡。结论肺癌合并NTM感染是罕见的肺部疾病,在肺癌的诊治过程中,局限性肿块的穿刺后要反复检测来诊断是否NTM感染与肺癌合并发生,尤其是对于已经确诊肺癌的高危患者,如出现间质性肺病、支气管扩张及新辅助免疫的相关治疗等因素,需要进一步明确是否存在NTM感染。

关键词：肺癌非结核菌分枝杆菌感染孤立肿块分子病理诊断

Superconductivity in ThMo_2Si_2C with Mo_2C square net

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Science China(Physics,Mechanics & Astronomy) 2021年第7期64卷 120-125页

作者： zichen liu BaiZhuo Li YuSen Xiao QingChen Duan YanWei Cui YuXue Mei Qian Tao ShuLi Wei ShuGang Tan Qiang Jing Qing Lu YuPing Sun YunYan liu ShengGui Fu Hao Jiang Zhi Ren ZhuAn Xu Cao Wang GuangHan Cao School of Physics and Optoelectronic Engineering Shandong University of TechnologyZibo255000China Department of Physics Zhejiang Province Key Laboratory of Quantum Technology and DevicesInterdisciplinary Center for Quantum Informationand State Key Lab of Silicon MaterialsZhejiang UniversityHangzhou310027China School of Science Westlake UniversityHangzhou310064China School of Physics and Optoelectronics Xiangtan UniversityXiangtan411105China

We report the superconductivity of a new quaternary compound ThMo_(2)Si_(2)C, synthesized with the arc-melting technique. The compound crystallizes in a tetragonal CeCr_(2)Si_(2)C-type structure with cell parameters of a = 4.2296A and c = 5.3571 A. An interlayer Si–Si covalent bonding is suggested by the atomic distance. The electrical resistivity and magnetic susceptibility measurements indicate a Pauli-paramagnetic metal with dominant electron-electron scattering in the normal-state. Bulk superconductivity at 2.2 K is demonstrated with a dimensionless specific-heat jump of △C/γnT = 0.98. The superconducting parameters of the critical magnetic fields, coherence length, penetration depth, and superconducting energy gap are given.

关键词： superconductivity quaternary compound physical properties

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戈壁区露天矿无组织扬尘源定量预测研究

煤炭工程 2024年第8期56卷 25-31页

作者：刘子晨中煤科工集团北京华宇工程有限公司北京100120

定量预测戈壁区露天矿开发过程中风蚀扰动和机械扰动产生的无组织扬尘的浓度和影响范围是露天矿大气环境影响评价的重点和难点。以红沙梁露天矿为研究对象,基于扬尘源颗粒物排放清单编制技术指南(试行)和ADMS-EIA软件,建立气象数据预处... 详细信息

定量预测戈壁区露天矿开发过程中风蚀扰动和机械扰动产生的无组织扬尘的浓度和影响范围是露天矿大气环境影响评价的重点和难点。以红沙梁露天矿为研究对象,基于扬尘源颗粒物排放清单编制技术指南(试行)和ADMS-EIA软件,建立气象数据预处理—无组织源强核算—模型定量预测的评价策略,以等值线图可视化扬尘控制措施下TSP、PM_(10)和PM_(2.5)网格浓度。研究表明,露天矿开发无组织扬尘主要集中在扰动工作面1000 m范围内,相比定期洒水扬尘控制措施,使用化学覆盖剂对主导风向下风向500 m处TSP、PM_(10)和PM_(2.5)浓度贡献分别降低56%、56%和41%。露天矿无组织扬尘源定量化预测可为大气环境防护距离确定和污染控制措施可行性评估提供支撑。

关键词：露天矿无组织扬尘戈壁风蚀定量预测环境影响评价

基于最小化各向同性误差的LiDAR-双目相机标定方法

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华南理工大学学报（自然科学版） 2023年第2期51卷 1-9页

作者：陈忠刘梓琛张宪民华南理工大学机械与汽车工程学院广东广州510640

LiDAR(Laser Imaging,Detection,and Ranging,激光雷达)与双目相机的多模态数据融合是3D重建领域的一个重要研究方向,两种传感器各有优缺点,通过多模态数据融合可以实现互补,获得更好的重建效果。为了实现数据融合,首先需要将两种数据... 详细信息

LiDAR(Laser Imaging,Detection,and Ranging,激光雷达)与双目相机的多模态数据融合是3D重建领域的一个重要研究方向,两种传感器各有优缺点,通过多模态数据融合可以实现互补,获得更好的重建效果。为了实现数据融合,首先需要将两种数据统一到同一个坐标系下,LiDAR与相机之间外参的高精度标定结果对后续的3D重建十分重要。在LiDAR与相机的外参标定过程中,受LiDAR点云的稀疏性与其定位误差的影响,提取精确的特征点并构建正确的点对应关系是一个挑战性的问题。此外,LiDAR在球坐标系下完成测量工作,而大多数标定方法忽略这一特性,直接使用笛卡尔坐标测量结果进行标定,引入了沿坐标轴各向异性分布的误差,导致标定精度下降。针对该问题,有研究者提出了各向异性权重方法,但仍存在一些缺陷。文中提出了一种最小化LiDAR球坐标误差的LiDAR与双目相机标定方法。首先,提出了一种使用形心特征点的新的标定板,改善特征点的提取精度;其次,将各向异性的LiDAR笛卡尔坐标误差转换为各向同性的球坐标误差,直接最小化球坐标误差求解外参。实验研究表明,本文提出的各向同性误差法相比各向异性权重方法保证求解结果为全局最优,且在牺牲部分精度的前提下所需标定样本数大幅减少,在最优标定误差为2.75 mm的情况下牺牲3.6%的精度能够减少约54.5%的数据量。

关键词： LiDAR 双目相机各向异性标定