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Considerations and Experience in the Treatment of Lung Cancer with VMAT SBRT + DIBH in Arms-Down Position

International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2021年第2期10卷 69-80页

作者： Yulin Song Boris Mueller Kenneth Dow ziad saleh Xiaoli Tang Melissa Zinovoy Daphna Gelblum Borys Mychalczak Department of Medical Physics Memorial Sloan Kettering Cancer Center New York USA Department of Radiation Oncology Memorial Sloan Kettering Cancer Center New York USA

The arms-up position is the most common treatment position adopted for lung cancer patients treated with radiation therapy. However, many elderly or frail patients have shoulder problems and cannot tolerate such an overstretched position for an extended period. Therefore, the arms-down position becomes the only alternative for this group of patients during radiation therapy. Even though the arms-down position is not ideal, it does provide a stable and comfortable patient immobilization position for radiation treatments that require a longer delivery time, such as stereotactic body radiation therapy (SBRT). In this study, we designed a protocol to treat lung cancer patients with VMAT stereotactic body radiation therapy (VMAT SBRT) and deep inspiration breath-hold (DIBH) in the arms-down position. Our initial clinical experience with this protocol indicates that it is reliable for patient immobilization and accurate in delivered dosimetry.

关键词： Lung Cancer VMAT SBRT DIBH Arms-Down Position

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Novel Wavelet-Based Segmentation of Prostate CBCT Images with Implanted Calypso Transponders

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2017年第3期6卷 336-343页

作者： Yingxia Liu ziad saleh Yulin Song Maria Chan Xiang Li Chengyu Shi Xin Qian Xiaoli Tang Shandong Communication and Media College Jinan China Medical Physics Department Memorial Sloan Kettering Cancer Center New York NY USA Radiation Oncology North Shore Long Island Jewish Health System New Hyde Park NY USA

Segmentation of prostate Cone Beam CT (CBCT) images is an essential step towards real-time adaptive radiotherapy (ART). It is challenging for Calypso patients, as more artifacts generated by the beacon transponders are present on the images. We herein propose a novel wavelet-based segmentation algorithm for rectum, bladder, and prostate of CBCT images with implanted Calypso transponders. For a given CBCT, a Moving Window-Based Double Haar (MWDH) transformation is applied first to obtain the wavelet coefficients. Based on a user defined point in the object of interest, a cluster algorithm based adaptive thresholding is applied to the low frequency components of the wavelet coefficients, and a Lee filter theory based adaptive thresholding is applied on the high frequency components. For the next step, the wavelet reconstruction is applied to the thresholded wavelet coefficients. A binary (segmented) image of the object of interest is therefore obtained. 5 hypofractionated Calypso prostate patients with daily CBCT were studied. DICE, Sensitivity, Inclusiveness and ΔV were used to evaluate the segmentation result.

关键词： CBCT Prostate Segmentation Wavelets MWDH

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A Novel Technique to Validate Dosimetry for Single-Isocenter Multiple-Target VMAT Stereotactic Radiosurgery

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2021年第2期10卷 59-68页

作者： Yulin Song Miao Zhang Laszlo Voros Xiaoli Tang ziad saleh Weixing Cai Jeho Jeong Boris Mueller Borys Mychalczak Department of Medical Physics Memorial Sloan Kettering Cancer Center New York USA Department of Radiation Oncology Memorial Sloan Kettering Cancer Center New York USA

Each year, 170,000 cancer patients in the United States develop brain metastases. Many of them present with multiple small lesions. Historically, Linac-based stereotactic radiosurgery (SRS) was used to treat single solitary brain metastasis with a diameter of less than 3.0 cm, while whole brain radiation therapy (WBRT) was used to treat multiple brain metastases mainly as palliative therapy. Evidence-based practices reveal that WBRT results in poor treatment outcomes, with high local recurrence rates, decreased cognitive function, and even the onset of dementia. Recently, volumetric modulated arc therapy (VMAT) SRS has been tested as an alternative treatment to WBRT. Owing to its inherent complexity and high risk, it is imperative to perform rigorous testing prior to its clinical implementation. In this paper, we present a novel technique for dosimetry validation of VMAT SRS.

关键词： Brain Metastasis VMAT SRS WBRT Film Dosimetry

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Erratum to “Novel Wavelet-Based Segmentation of Prostate CBCT Images with Implanted Calypso Transponders” [International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 6 (2017) 336-343]

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2017年第4期6卷 376-376页

The original online version of this article (Liu, Y.X., saleh, Z., Song, Y.L., Chan, M., Li, X., Shi, C.Y., Qian, X. and Tang, X.L (2017) Novel Wavelet-Based Segmentation of Prostate CBCT Images with Implanted Calypso Transponders. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, 6, 336-343. doi: 10.4236/ijmpcero.2017.63030) was published without acknowledging our support. The authors wish to add the acknowledgments.

关键词： Erratum

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