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Establishment of predictive models and determinants of preoperative gastric retention in endoscopic retrograde cholangiopancreatography

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2574-2582页

作者： Ying Jia Hao-Jun Wu Tang Li Jia-Bin liu Ling Fang zi-ming liu Department of Thyroid Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Division of Biliary Tract Surgery Department of General SurgeryWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Division of General Surgery West China Hospital-Chengdu Shangjin NanfuWest China HospitalChengdu 611730Sichuan ProvinceChina

BACKGROUND Study on influencing factors of gastric retention before endoscopic retrograde cholangiopancreatography(ERCP)background:With the wide application of ERCP,the risk of preoperative gastric retention affects the smooth progress of the *** study found that female,biliary and pancreatic malignant tumor,digestive tract obstruction and other factors are closely related to gastric retention,so the establishment of predictive model is very important to reduce the risk of *** A retrospective analysis was conducted on 190 patients admitted to our hospital for ERCP preparation between January 2020 and February *** baseline clinical data were collected using an electronic medical record *** were randomly matched in a 1:4 ratio with data from 190 patients during the same period to establish a validation group(n=38)and a modeling group(n=152).Patients in the modeling group were divided into the gastric retention group(n=52)and non-gastric retention group(n=100)based on whether gastric retention occurred *** data of patients in the validation group and identify factors influencing preoperative gastric retention in ERCP patients.A predictive model for preoperative gastric retention in ERCP patients was constructed,and calibration curves were used for *** receiver operating characteristic(ROC)curve was analyzed to evaluate the predictive value of the *** We found no statistically significant difference in general data between the validation group and modeling group(P>0.05).The comparison of age,body mass index,hypertension,and diabetes between the two groups showed no statistically significant difference(P>0.05).However,we noted statistically significant differences in gender,primary disease,jaundice,opioid use,and gastrointestinal obstruction between the two groups(P<0.05).Mul-tivariate logistic regression analysis showed that gender,primary disease,jaundice,opioid use,and gastrointestina

关键词： Cholangiopancreatography Gastric retention Influencing factors Predictive model Endoscope

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Prediction model establishment and validation for enteral nutrition aspiration during hospitalization in patients with acute pancreatitis

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2583-2591页

作者： Ping Hou Hao-Jun Wu Tang Li Jia-Bin liu Quan-Qing Zhao Hong-Jiang Zhao zi-ming liu Division II of General Surgery West China Hospital-Chengdu Shangjin NanfuWest China HospitalSichuan UniversityChengdu 611730Sichuan ProvinceChina Division of Biliary Tract Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Hepatobiliary and Pancreatic Surgery West China Hospital-Chengdu Shangjin NanfuWest China HospitalSichuan UniversityChengdu 611730Sichuan ProvinceChina Department of Thyroid Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Oncology West China Hospital-Chengdu Shangjin NanfuWest China HospitalSichuan UniversityChengdu 611730Sichuan ProvinceChina Division of Biliary Tract Surgery Department of General SurgeryWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Acute pancreatitis(AP)is a disease caused by abnormal activation of pancreatic enzymes and can lead to self-digestion of pancreatic tissues and dysfunction of other *** nutrition plays a vital role in the treatment of AP because it can meet the nutritional needs of patients,promote the recovery of intestinal function,and maintain the barrier and immune functions of the ***,the risk of aspiration during enteral nutrition is high;once aspiration occurs,it may cause serious complications,such as aspiration pneumonia,and suffocation,posing a threat to the patient’s *** study aims to establish and validate a prediction model for enteral nutrition aspiration during hospitalization in patients with *** To establish and validate a predictive model for enteral nutrition aspiration during hospitalization in patients with *** A retrospective review was conducted on 200 patients with AP admitted to Chengdu Shangjin Nanfu Hospital,West China Hospital of Sichuan University from January 2020 to February *** data were collected from the electronic medical record *** were randomly divided into a validation group(n=40)and a modeling group(n=160)in a 1:4 ratio,matched with 200 patients from the same time *** modeling group was further categorized into an aspiration group(n=25)and a non-aspiration group(n=175)based on the occurrence of enteral nutrition aspiration during *** and multivariate logistic regression analyses were performed to identify factors influencing enteral nutrition aspiration in patients with AP during hospitalization.A prediction model for enteral nutrition aspiration during hospitalization was constructed,and calibration curves were used for *** operating characteristic curve analysis was conducted to evaluate the predictive value of the *** There was no statistically significant difference in general data between the validation and mode

关键词： Acute pancreatitis Hospitalization Enteral nutrition Predictive model Aspiration

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Who Is Looking After the Elderly?

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Women of China 1999年第4期 21-22页

作者： ming zi liu XIAOHONG

STATSTICS from the All-ChinaCommittee of the Elderly show that,since 1990,the population of thecountry’s elderly has grown annually by3.32 *** to experts,it willreach 132 million by the end of thiscentury;that will be 10.5 percent of theChinese *** that time,Chinawill have become another of the world’s“aged” *** kind of conditions arethe elderly in China living in today?Howare their families and society treating them?

关键词： Who Is Looking After the Elderly

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Peroral endoscopic myotomy for management of gastrointestinal motility disorder

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World Journal of Clinical Cases 2020年第11期8卷 2116-2126页

作者： Zhe Feng zi-ming liu Xiang-Lei Yuan Lian-Song Ye Chun-Cheng Wu Qing-Hua Tan Bing Hu Department of Gastroenterology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

Achalasia is a type of esophageal motility disorder,consisting of relaxation dysfunction of the lower esophagus and disturbed esophageal *** clinical symptoms include dysphagia,regurgitation,chest pain,and weight *** treatment options include endoscopic botulinum toxin injection,endoscopic pneumatic dilation,and laparoscopic Heller’s *** therapies mainly relieve symptoms by reducing the pressure on the lower esophageal sphincter and reducing blood flow resistance at the esophagogastric *** on endoscopic submucosal dissection and natural orifice transluminal endoscopic surgery,peroral endoscopic myotomy(POEM)is a purely endoscopic method of myotomy with minimal invasiveness and a low rate of adverse events when performed by experienced *** then,numerous studies have shown the significant clinical efficacy and safety of *** purpose of this article is to introduce different modified POEMs,special indications for different POEMs,and their advantages as well as disadvantages.

关键词： Endoscopy Achalasia Peroral endoscopic myotomy Esophageal diverticula Gastroparesis Pyloric stenosis

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Are Men and Women Equal in Employment?

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Women of China 1996年第4期 8-9页

作者： zi ming liu QIAN

EQUALITY was one of the themes of the Fourth World Conference on Women. The motto of the Conference was "Action for Equality, Development and Peace." But is there a real possibility for equality between men and women? Equality in employment remains an important concern. Recently, Zheng Yefu, research worker of the Beijing Academy of

关键词： Are Men and Women Equal in Employment

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Efficacy of endoscopic ultrasound in the evaluation of small gastrointestinal stromal tumors

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World Journal of Gastroenterology 2022年第37期28卷 5457-5468页

作者： Qi-Chao Ge Yu-Fan Wu zi-ming liu Zhe Wang Sheng Wang Xiang liu Nan Ge Jin-Tao Guo Si-Yu Sun Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Pathology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Gastrointestinal stromal tumors(GISTs)with a diameter of5/50 high power field in 8(3.1%)*** irregularity,ulceration,strong echo foci,and heterogeneity were detected in 1(0.4%),2(0.8%),22(8.6%),and 67(65.1%)patients,***,cystic changes were not *** size was positively correlated with the mitotic index(P1.48 cm was associated with higher risk classification(P1.48 cm)with positive EUS features should receive intensive surveillance or unde

关键词： Gastrointestinal stromal tumors Endoscopic ultrasound Diagnosis Risk classification

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Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao De-En Xu ming-Lei Wu Ji-Chuan liu zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

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对外传播中国文化的新途径——我国网络文学海外输出现状与思考

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编辑之友 2017年第8期 17-20页

作者：董子铭刘肖四川师范大学影视与传媒学院四川成都600068 四川大学马克思主义学院四川成都610207

我国网络文学在短短十几年间,从最初萌生到原创速增,再到走出国门、走遍东亚、走进欧美,其海外输出已走在世界前列。然而,网络文学对外传播在蓬勃发展的同时,更需要思考如何厘清现实、把握趋势、走向成熟。面对我国网络文学的境外民间... 详细信息

我国网络文学在短短十几年间,从最初萌生到原创速增,再到走出国门、走遍东亚、走进欧美,其海外输出已走在世界前列。然而,网络文学对外传播在蓬勃发展的同时,更需要思考如何厘清现实、把握趋势、走向成熟。面对我国网络文学的境外民间自发翻译活跃的现状,亟须建立网络文学译介推广机制,持续输出优质内容。针对我国网络文学呈现类型化主流化趋势,亟须构建网络文艺批评机制,探索与中国文化价值内涵的融合路径。

关键词：网络文学对外传播译介推广文艺批评

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Effects of ulinastatin on renal ischemia-reperfusion injury in rats

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Acta Pharmacologica Sinica 2004年第10期 94-100页

作者： Cong-cong CHEN, zi-ming liu, Hui-hua WANG, Wei HE, Yi WANG, Wei-dong WUDepartment of Anesthesiology, Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310009,China

AIM: To investigate the effect and possible mechanism of ulinastatin on renal ischemia-reperfusion injury in rats. METHODS: Male Sprague-Dawley rats were subjected to 45-min bilateral renal ischemia, treated with intravenously 12 500 U ulinastatin at 30 min prior to ischemia and at the beginning of reperfusion, compared with a nontreated group without ulinastatin and a sham-operation group without bilateral renal ischemia. After 0 h, 2 h, 6 h, 12 h, and 24 h of reperfusion, serum creatinine and blood urea nitrogen were measured for the assessment of renal function, renal sections were used for histologic grading of renal injury, for immunohistochemical localization of Bcl-2 and heat shock protein 70. Renal ultrastructure was observed through a transmission electron microscope. RESULTS: Ulinastatin significantly reduced the increase in blood urea nitrogen and creatinine produced by renal ischemia-reperfusion, suggesting an improvement in renal function. Ulinastatin reduced the histologic evidence of renal

关键词： reperfusion injury urinastatin immunohistochemistry ultrastructure

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Methods to increase the diagnostic efficiency of endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic lesions:An updated review

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World Journal of Gastrointestinal Endoscopy 2024年第3期16卷 117-125页

作者： Xin Yang zi-ming liu Xue Zhou Fan Yang Wen-Zhuang Ma Xin-Zhu Sun Si-Yu Sun Nan Ge Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

Endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)is a means to procure adequate specimens for histological and cytologic *** ideal EUS-FNA should be safe,accurate,and have a high sample adequacy rate and low adverse events *** recent years,many guidelines and trials on EUS-FNA have been *** purpose of this article is to provide an update on the influence of some of the main factors on the diagnostic efficiency of EUS-FNA as well as a rare but serious complication known as needle tract seeding.

关键词： Endoscopic ultrasound EUS-FNA Pancreatic cancer Diagnostic efficiency

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