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Effectiveness of cardioneuroablation in different subtypes of vasovagal syncope

Journal of Geriatric Cardiology 2024年第6期21卷 651-657页

作者： Bin TU zi-hao lai Ai-Yue CHEN Zhi-Yuan WENG Si-Min CAI Zhu-Xin ZHANG Li-Kun ZHOU Li-Hui ZHENG Yan YAO Arrhythmia Center Fuwai HospitalNational Center for Cardiovascular DiseasesNational Key LaboratoryChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Cardiac Center Beijing Chaoyang HospitalCapital Medical UniversityBeijingChina Cardiovascular Department The First Affiliated HospitalFujian Medical UniversityFujian Institute of HypertensionFujianChina Department of Cardiovascular The Second Affiliated Hospital of Zhejiang University School of MedicineZhejiangChina

BACKGROUND Cardioneuroablation(CNA)has shown encouraging results in patients with vasovagal syncope(VVS).However,data on different subtypes was *** This observational study retrospectively enrolled 141 patients[mean age:40±18 years,51 males(36.2%)]with the diagnosis of *** characteristics among different types of VVS and the outcomes after CNA were *** After a mean follow-up of 4.3±1.5 years,41 patients(29.1%)experienced syncope/pre-syncope events after ***/pre-syncope recurrence significantly differed in each subtype(P=0.04).The cardioinhibitory type of VVS had the lowest recurrence rate after the procedure(n=6,16.7%),followed by mixed(n=26,30.6%)and vasodepressive(n=9,45.0%).Additionally,a significant difference was observed in the analyses of the Kaplan-Meier survival curve(P=0.02).Syncope/pre-syncope burden was significantly reduced after CNA in the vasodepressive type(P<0.01).Vasodepressive types with recurrent syncope/pre-syncope after CNA have a lower baseline deceleration capacity(DC)level than those without(7.4±1.0 ms vs.9.0±1.6 ms,P=0.01).Patients with DC<8.4 ms had an 8.1(HR=8.1,95%CI:2.2-30.0,P=0.02)times risk of syncope/pre-syncope recurrence after CNA compared to patients with DC≥8.4 ms,and this association still existed after adjusting for age and sex(HR=8.1,95%CI:2.2-30.1,P=0.02).CONCLUSIONS Different subtypes exhibit different event-free *** vasodepressive type exhibited the lowest event-free rate,but those patients with DC≥8.4 ms might benefit from CNA.

关键词： syncope subtypes diagnosis

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Ultrasound-guided stellate ganglion blockade: an appealing tactic for cardiac electrical storm

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Journal of Geriatric Cardiology 2023年第5期20卷 376-382页

作者： zi-hao lai Li-Hui ZHENG Yan YAO Arrhythmia Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Ventricular arrhythmia(VA)is a life-threatening cardiac *** VA occurs three times or more within 24 h and interventions are required,it is defined as an electrical storm(ES)characterized by refractoriness and recurrence.[1]For patients with implantable cardioverter defibrillator(ICD),the notion is redefined as no fewer than three appropriate and separate(at least 5 min for each interval)ICD interventions given within 24 h.

关键词： cardiac storm electrical

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Enhancing force sensing in a squeezed optomechanical system with quantum nondemolition measurement

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Communications in Theoretical Physics 2024年第1期76卷 49-60页

作者： Shi-Lei Chao zi-hao Li Xin-You Lü School of Physics Huazhong University of Science and Technology430074 WuhanChina

A theoretical scheme is proposed to enhance the sensitivity of force sensors with quantum nondemolition measurement(QND)in an optomechanical setup assisted by four-tone optical driving and an optical parametric amplifier(OPA).With the help of special drive,the system can be simplified as the typical type of QND for force sensing,so that the backaction noise can be evaded to surpass the standard quantum ***,the added noise can be suppressed owing to the modified optical susceptibility resulting from the *** introducing two oscillators coupling with two charged bodies respectively,the signal can be enhanced with the nonlinearity caused by Coulomb interaction,while the noise presents an exponential ***,considering the homodyne detection effect,the range of system parameters and frequency bands will be *** present investigation may provide a route toward simultaneously evading backaction noise,reducing the mechanical thermal noise,and enhancing the external signal,which can be an alternative design for sensitive devices.

关键词： force sensing optical parametric amplifier quantum non-demolition measurement optomechanical system

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Nonreciprocal generation of Schrodinger cat state induced by topology

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 23-30页

作者： zi-hao Li Li-Li Zheng Ying Wu Xin-You Lü School of Physics and Institute for Quantum Science and Engineering Huazhong University of Science and Technologyand Wuhan Institute of Quantum TechnologyWuhan 430074China Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education Jianghan UniversityWuhan 430074China

The Schrodinger cat state produced differently in two directions is anticipated to be a critical quantum resource in quantum information *** exploring the interplay between quantum nonreciprocity and topology in a one-dimensional microcavity array,we obtain the Schrodinger cat state(a pure quantum state)in a chosen direction at the edge cavity,whereas a classical state in the other *** nonreciprocal generation of the cat state originates from the topologically protected chiralitymode excitation in the nontrivial phase,but in the trivial phase,the nonreciprocal generation of cat state ***,our proposal is switchable by tuning the parameters so that a topological phase transition ***,the obtained cat state has nonreciprocal high fidelity,nonclassicality,and quantum coherence,which are sufficient to be used in various one-way quantum technologies,e.g.,invisible quantum sensing,noise-tolerant quantum computing,and chiral quantum *** work provides a general approach to control quantum nonreciprocities with the topological effect,which substantially broadens the fields of nonreciprocal photonics and topological physics.

关键词： Schr?dinger cat state nonreciprocity topology

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Realizing high initial Coulombic efficiency in manganese-based layered oxide cathodes for sodium-ion batteries via P2/O'3 biphasic structure optimization

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Rare Metals 2024年第5期43卷 2093-2102页

作者： Bo Peng zi-hao Zhou Ping Xuan Jie Xu Lian-Bo Ma School of Materials Science and Engineering Anhui University ofTechnologyMa'anshan 243002China Anhui Product Quality Supervision&Inspection Research Institute Hefei 230051China

Mn-based layered oxides are among the most promising cathode materials for sodium-ion batteries owing to the advantages of abundance,environmenta friendliness,low cost and high specific capacity.P2 and O'3 are two representative structures of Mn-based layered ***,the P2 structure containing insufficien Na generally exhibits low initial charge capacity,while O'3structure with sufficient Na delivers high initial charge capacity but poor cycle *** study prepared a multitude of Na_(x)MnO_(2)(x=0.7,0.8,0.9)cathode materials with varying P2/O'3 ratios and further investigated their electrochemical *** optimized Na_(0.8)MnO_(2) comprising 69.9 wt%O'3 and 30.1 wt%P2 phase,exhibited relatively balanced specific capacity,Coulombic efficiency and cycle ***,it achieved a high specific capacity of 128.9 mAh·g^(-1) with an initia Coulombic efficiency of 98.2%in half-cell configuration The Na_(0.8)MnO_(2)//hard carbon full cell also achieved a high specific capacity of 126.7 mAh·g^(-1) with an initia Coulombic efficiency of 98.9%.Moreover,the capacity fading mechanism was revealed by combining in-situ and ex-situ X-ray *** findings of this study provide theoretical guidance for further modification design of Mnbased layered cathodes.

关键词： Sodium-ion batteries Cathode materials Mn-based layered oxides P2/0'3 composites

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Coexistence of All-Order Topological States in a Three-Dimensional Phononic Topological Crystalline Insulator

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Research 2024年第2期2023卷 511-518页

作者： Hua-Shan lai hao Chen Chu-hao Xia Si-Yuan Yu Cheng He Yan-Feng Chen National Laboratory of Solid State Microstructures&Department of Materials Science and Engineering Nanjing UniversityNanjng 210093China Collaborative Innovation Center of Advanced Microstructures Nanjing University Nanjng 210093China Jiangsu Key Laboratory of Artificial Functional Materials Nanjing University Nanjing 210093China

Classical-wave topological materials lacking intrinsic half-integer spins are less robust while more ***,we explore a single 3-dimensional phononic topological crystalline insulator that simultaneously exhibits a whole family of first-order quadratic surface,second-order hinge,and third-order corner states within the same *** a topological crystalline insulator hosting all-order phases originates from the different topological nature when hierarchically projected onto different facets and lower dimensions,thus free from trivial cladding *** work offers an ideal platform for either robust wave propagation or localization in on-demand dimensions and may facilitate dimension division multiplexing technology.

关键词： topological dimensions crystalline

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Experimental research on the launching system of auxiliary charge with filter cartridge structure

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Defence Technology（防务技术） 2024年第1期31卷 41-48页

作者： zi-Jun Chen Ze He Hong-hao Ma Lu-Qing Wang Zhao-Wu Shen CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefeiAnhui230027PR China State Key Laboratory of Fire Science University of Science and Technology of ChinaHefeiAnhui230026PR China

A launching system with a filter cartridge structure was proposed to improve the muzzle velocity of the *** combustion chamber of the launching system is divided into two fixed chambers,one is located in the breech chamber,and the other is arranged in the *** breech chamber charge was ignited first,and the charges in the auxiliary chambers were ignited by the high-temperature,highpressure combustible gas trailing the *** this way,the combustible gas in the auxiliary chambers could compensate for the pressure drop caused by the movement of the *** proposed device features the advantage of launching a projectile with high muzzle velocity without exceeding the maximum pressure in the *** order to obtain some internal ballistic characteristics of the launch system,some critical structure,such as the length of the filter cartridge auxiliary charge,the combustion degree of the propellant in the chamber,and the length of the barrel,are *** experimental results show that with the increased auxiliary charge length,a pressure plateau or even a secondary peak pressure can be formed,which is less than the peak *** projectile velocity increased by 23.57%,14.64%,and 7.65%when the diaphragm thickness was 0 mm,1 mm,and2 mm,*** muzzle velocity of the projectile can be increased by 13.42%by increasing the length of the *** the same charge condition,with the increase of barrel length,the energy utilization rate of propellant increases by 28.64%.

关键词： Interior ballistics Charge structures Launch system Charge design

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Pharmacological Effects of Botanical Drugs on Myocardial Metabolism in Chronic Heart Failure

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Chinese Journal of Integrative Medicine 2024年第5期30卷 458-467页

作者： HU Yu-xuan QIU Sheng-lei SHANG Ju-ju WANG zi lai Xiao-lei Beijing Hospital of Traditional Chinese Medicine Capital Medical UniversityBeijing 100010China

Although there have been significant advances in the treatment of heart failure in recent years,chronic heart failure remains a leading cause of cardiovascular disease-related *** studies have found that targeted cardiac metabolic remodeling has good potential for the treatment of heart ***,most of the drugs that increase cardiac energy are still in the theoretical or testing *** research has found that botanical drugs not only increase myocardial energy metabolism through multiple targets but also have the potential to restore the balance of myocardial substrate *** this review,we summarized the mechanisms by which botanical drugs(the active ingredients/formulas/Chinese patent medicines)improve substrate utilization and promote myocardial energy metabolism by activating AMP-activated protein kinase(AMPK),peroxisome proliferator-activated receptors(PPARs)and other related *** the same time,some potential protective effects of botanical drugs on myocardium,such as alleviating oxidative stress and dysbiosis signaling,caused by metabolic disorders,were briefly discussed.

关键词： botanical drugs chronic heart failure myocardial metabolism pharmacological effects review

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Dynamical switchable quantum nonreciprocity induced by off-resonant chiral two-photon driving

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 31-37页

作者： Da-Wei Liu zi-hao Li Shi-Lei Chao Ying Wu Liu-Gang Si School of Physics and Institute for Quantum Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China

Optical nonreciprocity,which refers to the direction-dependent emission,scattering and absorption of photons,plays a very important role in quantum engineering and quantum information ***,we propose an all-optical approach to achieve the optical dynamical switchable quantum nonreciprocity by an off-resonant chiral two-photon driving in a single microring cavity,which differs from the conventional nonreciprocal *** is shown that the optical field with time-dependent statistical properties can be generated and the nonreciprocity flips periodically,with switchable photon blockade and photon-induced tunneling *** find that the dynamical system is robust and immune to the parameter variations,which loosens the parameter range of ***,the time window for one-way quantum information is sufficiently wide and *** work opens a new idea for the current quantum nonreciprocal research,which can facilitate a memory functionality and be used for future inmemory superconducting quantum *** other nonreciprocal quantum devices,i.e.,dynamical switchable nonreciprocal squeezing and entanglement,may be inspired by our method,which is expected to have important applications in future quantum technology.

关键词： dynamical switchable nonreciprocity single-photon source chiral two-photon driving

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Antiviral treatment standards for hepatitis B:An urgent need for expansion

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World Journal of Gastroenterology 2024年第4期30卷 418-420页

作者： zi-Hong Bao Zhi-Kun Dai hao-Xian Tang Department of Infectious Diseases The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Medical College Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of Cardiology The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The present letter to the editor is related to the review with the title“Past,present,and future of long-term treatment for hepatitis B virus.”Chronic hepatitis B(CHB)represents an important and pressing public health *** identification and effective antiviral therapy hold the potential to reduce liver-related mortality attributable to chronic infection with hepatitis B virus(HBV)***,the current global treatment rates for CHB remain conspicuously low,with the excessively stringent treatment criteria advocated by national CHB guidelines being a contributing factor to these low ***,recent strides in comprehending this malady and the emergence of novel antiviral agents prompt the imperative re-evaluation of treatment standards to extend the sphere of potential *** impending need arises for a novel paradigm for the classification of patients with CHB,the expansion of antiviral treatment eligibility for HBV-infected individuals,and even the streamlining of the diagnostic process for CHB to amplify cost-effectiveness and augment survival prospects.

关键词： Hepatitis B virus Chronic hepatitis B Antiviral treatment criteria Serum alanine aminotransferase Liver-related mortality Letter to the Editor

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