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Effects of 105 traditional Chinese medicines on the detection ofβ-agonists in medicine extracts and swine urine based on colloidal gold immunochromatographic assay

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Journal of Integrative Agriculture 2021年第6期20卷 1626-1635页

作者： WANG zi-lin FENG Ke-ying GE Xiu-feng MAI jia-cheng WANG Han-chuan LIU Wen-zi ZHANG jia-hui SHEN Xiang-guang Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation South China Agricultural UniversityGuangzhou 510642P.R.China Animal and Poultry Products Quality Control Inspection and Testing CenterMinistry of Agriculture and Rural AffairsGuangzhou 510642P.R.China

Colloidal gold immunochromatographic assay(CGIA)is commonly used for the on-site detection ofβ-agonists that are sometimes used illegally as feed additives in swine ***,few studies have evaluated the causes of false-positive results that sometimes occur when applying CGIA in agricultural *** this study,we investigated if this false-positive phenomenon is related to the addition of certain traditional Chinese medicines(TCMs)to swine *** established and verified an extraction method for TCMs,and then applied CGIA to detectβ-agonists in the extracts of 105 TCMs and in the urine of swine dosed with TCMs,*** chromatography-tandem mass spectrometry was used to validate the results of the urine samples tested positive forβ-agonists using *** results were also verified using TCMs and colloidal gold test strips produced by different *** extracts of Citri Reticulatae Pericarpium Viride,Citri Reticulatae Pericarpium,Magnoliae Officinalis Cortex,Chaenomelis Fructus,and Rhodiolae Crenulatae Radix Et Rhizoma were tested positive forβ-***,the addition of Citri Reticulatae Pericarpium Viride and Citri Reticulatae Pericarpium to swine feed resulted in false-positive results forβ-agonists in swine *** results provide a new way to explain false-positive CGIA results and provide valuable information for livestock feeding programs.

关键词： colloidal gold immunochromatographic assay false positive traditional Chinese medicine β-agonists swine urine

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Application of energy,electronic and interface bonding properties in highly reliable brazing joints between dissimilar materials

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Journal of Iron and Steel Research International 2024年第10期31卷 2344-2364页

作者： Xing-xing Wang Yuan-long jiang jia-shuo chang Zhi-peng Yuan jian-jun Shi zi-cheng Ling Jun-yi jiang Hong-gang Dong Fei Gao Jinhua Shuanghuan Brazing Alloys Co. Ltd.Jinhua321000ZhejiangChina School of Materials Science and Engineering Dalian University of TechnologyDalian116024LiaoningChina Henan International Joint Laboratory of High-Efficiency Special Green Welding North China University of Water Resources and Electric PowerZhengzhou450045HenanChina Luoyang Bearing Research Institute Co. Ltd.Luoyang471000HenanChina

Brazing,an important welding and joining technology,can achieve precision joining of materials in advanced *** the first principle calculation is a new material simulation method in high-throughput *** can calculate the interfacial structure,band structure,electronic structure,and other properties between dissimilar materials,predicting various *** plays an important role in assisting practical research and guiding experimental designs by predicting material *** can largely improve the quality of welded components and joining *** relevant theoretical foundation is reviewed,including the first principle and density functional ***-correlation functional and pseudopotential plane wave approach was also ***,the latest research progress of the first principle in brazing was also *** application of first principle calculation mainly includes formation energy,adsorption energy,surface energy,adhesion work,interfacial energy,interfacial contact angle,charge density differences,density of states,and mulliken *** energy,mechanical,and electronic properties were ***,the limitations and shortcomings of the research in the first principle calculation of brazed interface were pointed *** developmental directions were presented to provide reference and theoretical basis for realizing high-throughput calculations of brazed joint interfaces.

关键词： Brazing First principle Joining interface Density functional theory Bonding property Dissimilar material

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Artificial intelligence in individualized retinal disease management

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International Journal of Ophthalmology(English edition) 2024年第8期17卷 1519-1530页

作者： zi-Ran Zhang jia-Jun Li Ke-Ran Li The Affiliated Eye Hospital of Nanjing Medical University Nanjing 210029Jiangsu ProvinceChina Nanjing Medical University Nanjing 210029Jiangsu ProvinceChina

Owing to the rapid development of modern computer technologies,artificial intelligence(AI)has emerged as an essential instrument for intelligent analysis across a range of *** has been proven to be highly effective in ophthalmology,where it is frequently used for identifying,diagnosing,and typing retinal *** increasing number of researchers have begun to comprehensively map patients’retinal diseases using AI,which has made individualized clinical prediction and treatment *** include prognostic improvement,risk prediction,progression assessment,and interventional therapies for retinal *** have used a range of input data methods to increase the accuracy and dependability of the results,including the use of tabular,textual,or image-based input *** also combined the analyses of multiple types of input *** give ophthalmologists access to precise,individualized,and high-quality treatment strategies that will further optimize treatment outcomes,this review summarizes the latest findings in AI research related to the prediction and guidance of clinical diagnosis and treatment of retinal diseases.

关键词： artificial intelligence artificial intelligence in ophthalmology retinal disease

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Extended-state-observer-based robust torsional vibration suppression for rolling mill main drive system with input saturation

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Journal of Iron and Steel Research International 2023年第5期30卷 985-993页

作者： jia-qiang Chen Shu-zong Chen chang-chun Hua Cheng jia Cheng Qian Institute of Electrical Engineering Yanshan UniversityQinhuangdao 066004HebeiChina National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan UniversityQinhuangdao 066004HebeiChina

A robust torsional vibration suppression strategy is proposed for the main drive system of the rolling mill subject to uncertainties,disturbances and input *** given model information incorporated into observer design,an extended state observer that relies only on roller speed measurements is developed to estimate the system states and lumped uncertainties of the rolling mill main drive *** handle the motor torque saturation,an auxiliary signal system with the same order as the plant is *** error between the control input and plant input is taken as the input of the constructed auxiliary system,and a number of signals are generated to compensate for the effect of the motor torque ***,a robust output feedback controller is introduced to obtain better transient and steady-state performance of the rolling mill main drive system and the stability of the closed-loop system is strictly proved via Lyapunov ***,comparative simulations are performed to verify the effectiveness and superiority of the proposed control strategy.

关键词： Rolling mill Main drive system Vibration suppression Extended state observer Input saturation

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Effect of sintering parameters on the microstructure and thermal conductivity of diamond/Cu composites prepared by high pressure and high temperature infiltration

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International Journal of Minerals,Metallurgy and Materials 2013年第2期20卷 180-186页

作者： Hui Chen Cheng-chang jia Shang-jie Li School of Materials Science and Engineering University of Science and Technology Beijing Shenzhen Haimingrun Industrial Co. Ltd.

Pure Cu composites reinforced with diamond particles were fabricated by a high pressure and high temperature （HPHT） infiltration technique. Their microstructural evolution and thermal conductivity were presented as a function of sintering parameters （temperature, pressure, and time）. The improvement in interfacial bonding strength and the maximum thermM conductivity of 750 W/（m.K） were achieved at the optimal sintering parameters of 1200℃, 6 GPa and 10 min. It is found that the thermal conductivity of the composites depends strongly on sintering pressure. When the sintering pressure is above 6 GPa, the diamond skeleton is detected, which greatly contributes to the excellent thermal conductivity.

关键词： metallic matrix composites particle reinforced composites copper diamonds infiltration microstructuralevolution thermal conductivity

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Advances in biotechnological production of santalenes and santalols

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Chinese Herbal Medicines 2021年第1期13卷 90-97页

作者： Wen-long Zha jia-chen zi Biotechnological Institute of Chinese Materia Medica Jinan UniversityGuangzhou 510632China College of Pharmacy Jinan UniversityGuangzhou 510632China

Sandalwood essential oil has been widely used not only as natural medicines but also in perfumery and food industries, with sesquiterpenoids as its major components including(Z)-a-santalol and(Z)-bsantalol and so on. The mature heartwoods of Santalum album, Santalum austrocaledonicum and Santalum spicatum are the major plant resources for extracting sandalwood essential oil, which have been overexploited. Synthetic biology approaches have been successfully applied to produce natural products on large scale. In this review, we summarize biosynthetic enzymes of santalenes and santalols, including various santalene synthases(STSs) and cytochrome P450 monooxygenases(CYPs), and then highlight the advances of biotechnological production of santalenes and santalols in heterologous hosts, especially metabolic engineering strategies for constructing santalene-and santalol-producing Saccharomyces cerevisiae.

关键词： biosynthesis biotechnological production sandalwood oil santalenes santalols

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法国英语教材价值观呈现研究

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外语学刊 2025年第1期 78-85页

作者：谈佳北京外国语大学法语语言文化学院北京100089

本文梳理了法国阿歇特出版社中学英语教材Teen Time的价值观呈现方式。研究发现,教材选择呈现的价值元素,不仅对应欧洲价值观调查揭示的法国人坚持的价值观,同时也是英语素材所承载的目的语国家所认同的价值观,反复出现的“社团活动、... 详细信息

本文梳理了法国阿歇特出版社中学英语教材Teen Time的价值观呈现方式。研究发现,教材选择呈现的价值元素,不仅对应欧洲价值观调查揭示的法国人坚持的价值观,同时也是英语素材所承载的目的语国家所认同的价值观,反复出现的“社团活动、规则意识、文化多样性和生态保护”,反映出在与他人、与社会以及与自然关系上法国与英语国家的共同态度和期许。Teen Time通过标题引领、图文呼应和文化板块拓展深入的呈现方式,传递价值观,并设置层层任务,让学习者在行动中体验,将价值观内化于心、外化于行,实现外语教学的育人功能,其价值观的选取角度和呈现方式对我国中学外语教材的编写具有一定的借鉴意义。

关键词：价值观呈现方式法国英语教材中学行动中体验

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Hoxc13/β-catenin Correlation with Hair Follicle Activity in Cashmere Goat

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Journal of Integrative Agriculture 2012年第7期11卷 1159-1166页

作者： WU jiang-hong ZHANG Yan-jun ZHANG jia-xin chang zi-li LI Jin-quan YAN Zu-wei Husile ZHANG Wen-guang Key Laboratory of Animal Genetics Breeding and Reproduction Inner Mongolian Autonomous Region Hohhot 010018 P.R.China College of Animal Science Inner Mongolia Agricultural University Hohhot 010018 P.R.China College of Science Inner Mongolia Agricultural University Huhhot 010018 P.R.China

Seasonal hair follicle activity and fibre growth in some Cashmere-bearing goats （Caprus hircus） is a cyclic process that is well characterized morphologically but understood incompletely at the molecular level. As an initial step in discovering regulators in hair-follicle activity and cycling, we used qPCR to investigate 19 genes expression in Cashmere goat side skin from 12 mon. Many of these genes may be associated with the hair follicle development-relevant genes （HFDRGs） in the literature. Here we show that Hoxc13/β-catenin gene associated with the follicle activity. In addition, Hoxc13 was found to be expressed with an drastic increase between July and November for melatonin treatments. To further investigate the role of Hoxcl3 on HFDRGs, fibroblasts and keratinocytes from Cashmere goat skin were transfected with p-ECFP- Hoxc13. The result suggested that overexpression ofHoxcl3 gene decreased HFDRGs with negative role for hair follicle development and increase HFDRGs with positive role for hair follicle development in vitro. These findings provide data on the Hoxc13 expression profile of normal Cashmere goat skin and Cashmere goat skin with melatonin treatment, and demonstrate hair-follicle-activity dependent regulation of Hoxc13 expression.

关键词： Hoxcl3 β-catenin Cashmere goat hair follicle activity cycle

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A global analysis searching for neutrinos associated with black hole merger gravitational wave events

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Research in Astronomy and Astrophysics 2018年第11期18卷 11-16页

作者： Yu-zi Yang jia-Jie Ling Wei Wang Zhao-Kan Cheng School of Physics Sun Yat-sen University School of Science Harbin Institute of Technology

Several neutrino observatories have searched for coincident neutrino signals associated with gravitational waves induced by the merging of two black holes. No statistically significant neutrino signal in excess of the background level was observed. These experiments use different neutrino detection technologies and are sensitive to various neutrino types. A combined analysis was performed on the KamLAND, Super-Kamiokande and Borexino experimental data with a frequentist statistical approach to achieve a global picture of the associated neutrino fluence. Both monochromatic and Fermi-Dirac neutrino spectra were assumed in the calculation. The final results are consistent with null neutrino signals associated with the process of a binary black hole merger. The derived 90% confidence level upper limits on the fluence and luminosity of various neutrino types are presented for neutrino energy less than110 MeV.

关键词： gravitational wave black hole merger neutrino fluence global analysis

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Recent Advances in Energy Chemical Engineering of Next-Generation Lithium Batteries

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Engineering 2018年第6期4卷 831-847页

作者： Xue-Qiang Zhang Chen-zi Zhao jia-Qi Huang Qiang Zhang Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China

Rechargeable lithium-ion batteries(LIBs)afford a profound impact on our modern daily ***,LIBs are approaching the theoretical energy density,due to the inherent limitations of intercalation chemistry;thus,they cannot further satisfy the increasing demands of portable electronics,electric vehicles,and ***,battery chemistries beyond LIBs are being widely ***-generation lithium(Li)batteries,which employ Li metal as the anode and intercalation or conversion materials as the cathode,receive the most intensive interest due to their high energy density and excellent potential for ***,significant progress has been achieved in Li batteries attributed to the increasing fundamental understanding of the materials and reactions,as well as to technological *** review starts by summarizing the electrolytes for next-generation Li *** challenges and recent progress in lithium-ion,lithium–sulfur,and lithium–oxygen batteries are then reviewed from the perspective of energy and chemical engineering ***,possible directions for further development in Li batteries are ***-generation Li batteries are expected to promote the sustainable development of human civilization.

关键词： Lithium-ion batteries Lithium–sulfur batteries Lithium–oxygen batteries Lithium metal Solid-state batteries Battery chemistry Electrolyte

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