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Nano Research 2024年第4期17卷 2574-2591页

作者： Guoyin Zhu Qingzhu Wu Xianghua Zhang Yuwen Bao Xuan Zhang zhuoyao shi Yizhou Zhang Lianbo Ma Institute of Advanced Materials and Flexible Electronics(IAMFE) School of Chemistry and Materials ScienceNanjing University of Information Science&TechnologyNanjing 210044China School of Materials Science and Engineering Anhui University of TechnologyMaanshan 243002China School of Mechanical Engineering Jiangsu University of TechnologyChangzhou 213001China

Lithium-sulfur(Li-S)batteries,known for their high energy density,are attracting extensive research interest as a promising next-generation energy storage ***,their widespread use has been hampered by certain issues,including the dissolution and migration of polysulfides,along with sluggish redox *** sulfides present a promising solution to these obstacles regarding their high electrical conductivity,strong chemical adsorption with polysulfides,and remarkable electrocatalytic capabilities for polysulfide *** this review,the recent progress on the utilization of metal sulfide for suppressing polysulfide shuttling in Li-S batteries is systematically summarized,with a special focus on sulfur hosts and functional *** critical roles of metal sulfides in realizing high-performing Li-S batteries have been comprehensively discussed by correlating the materials’structure and electrochemical ***,the remaining issues/challenges and future perspectives are *** offering a detailed understanding of the crucial roles of metal sulfides,this review dedicates to contributing valuable knowledge for the pursuit of high-efficiency Li-S batteries based on metal sulfides.

关键词： lithium-sulfur batteries metal sulfides polysulfide shuttling sulfur hosts separator coating layers

Long-term in vivo chimeric cells tracking in non-human primate

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Protein & Cell 2024年第3期15卷 207-222页

作者： Junmo Wu Yu Kang Xiang Luo Shaoxing Dai Yuxi shi zhuoyao Li Zengli Tang Zhenzhen Chen Ran Zhu Pengpeng Yang Zifan Li Hong Wang Xinglong Chen Ziyi Zhao Weizhi ji Yuyu Niu State Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China Yunnan Key Laboratory of Primate Biomedical Research Kunming 650500China Faculty of Life Science and Technology Kunming University of Science and TechnologyKunming 650500China

Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology ***,given the ethical issues and costs associated with this model,it would be highly advantageous to use NHP cellular models in clinical ***,developing and maintaining the naive state of primate pluripotent stem cells(PSCs)remains difficult as does in vivo detection of PSCs,thus limiting biotech-nology application in the cynomolgus ***,we report a chemically defined,xeno-free culture system for culturing and deriving monkey PSCs in *** cells display global gene expression and genome-wide hypometh-ylation patterns distinct from monkey-primed *** also found expression of signaling pathways components that may increase the potential for chimera *** for biomedical applications,we were also able to integrate bioluminescent reporter genes into monkey PsCs and track them in chimeric embryos in vivo and in *** engineered cells retained embryonic and extra-embryonic developmental ***,we generated a chimeric monkey carrying bioluminescent cells,which were able to track chimeric cells for more than 2 years in living *** study could have broad utility in primate stem cell engineering and in utilizing chimeric monkey models forclinical studies.

关键词： pluripotent stem cells bioluminescence imaging non-human primates

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基于挠性梁结构的电推进器推力测量方法研究

核技术 2024年第5期47卷 91-101页

作者：王洛麒郑金星刘海洋李飞孟东东陆玉东杜宜凡唐卓尧吴涛史佳明中国科学技术大学合肥230026 中国科学院合肥物质科学研究院合肥230031 中国科学院力学研究所高温气体动力学国家重点实验室北京100190 北京工业大学机械与能源工程学院北京100124

电推进系统在空间任务中相比于传统化学燃料推进工作寿命更长、燃料消耗更低,在近年来备受关注。但基于可控核聚变思想研发的高功率霍尔效应电推进器,其推力很难测量,原因在于这些电推进器需要在高温环境下电离推进剂,所以工作时会产生... 详细信息

电推进系统在空间任务中相比于传统化学燃料推进工作寿命更长、燃料消耗更低,在近年来备受关注。但基于可控核聚变思想研发的高功率霍尔效应电推进器,其推力很难测量,原因在于这些电推进器需要在高温环境下电离推进剂,所以工作时会产生高温等离子体羽流,导致传统推力测试方法无法准确测量其推力。推进器推力的准确测量直接关系到航天器姿态以及轨道保持的控制精度,因此必须在地面测试中准确地测量推力。本文设计并搭建了一套基于挠性梁结构的推力测量平台,可以在高温环境下测量电推进器产生的推力。实验结果表明,以可变比冲磁等离子体火箭为例,在中心磁场强度0.2 T、质量流率为20 mg·s-1的工况下,实时测得电推进器推力为266.5 mN,证明了测量平台的可行性,为后续电推进器推力测量实验提供参考。

关键词：电推进器可控核聚变等离子体挠性梁推力测量

磁等离子体推进器阳极半径对阳极功率沉降的影响

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核技术 2024年第5期47卷 82-90页

作者：唐卓尧郑金星刘海洋陆玉东杜宜凡柯茂林王洛麒吴梅起吴涛史佳明中国科学院合肥物质科学研究院等离子体物理研究所合肥230031 中国科学技术大学合肥230026

随着人类航天事业的发展,需要研发适用于不同空间任务的推进系统,与磁约束核聚变原理类似的磁等离子体动力推进器(MegnetoPlasmaDynamic Thruster,MPDT)在推力功率比和比冲方面具有优越性能。阳极功率沉降是MPDT运行过程中等离子体与壁... 详细信息

随着人类航天事业的发展,需要研发适用于不同空间任务的推进系统,与磁约束核聚变原理类似的磁等离子体动力推进器(MegnetoPlasmaDynamic Thruster,MPDT)在推力功率比和比冲方面具有优越性能。阳极功率沉降是MPDT运行过程中等离子体与壁面相互作用的结果,占总功率的40%~90%,严重降低推进器效率。针对该问题,本文从阳极功率沉降的角度探究了阳极半径对推进器效率的影响。基于磁流体力学方程(MagnetoHydroDynamic,MHD),利用数值计算方法建立径向放电参数数值模型和阳极功率沉降物理模型,研究计算了阳极半径对放电参数和阳极功率沉降的影响规律,并建立热仿真模型对阳极水冷散热结构进行了热仿真。研究结果表明:增大阳极半径,电子密度及离子速度得到提高,阳极功率沉降增大,但阳极功率沉降分数降低,推进器效率得到提升。热仿真结果显示,水冷结构阳极在输入阳极功率沉降约为3 kW时,对应的阳极冷却水温差为5 K。本研究验证了阳极功率沉降物理模型的可靠性,并指出增大阳极半径是提升推进器效率的有效手段。

关键词：磁等离子体推进器阳极功率沉降数值计算热仿真磁流体力学方程

Current state of stem cell research in non-human primates:an overview

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Medical Review 2023年第4期3卷 277-304页

作者： Junmo Wu Yuxi shi Shanshan Yang Zengli Tang Zifan Li zhuoyao Li Jiawei Zuo Weizhi Ji Yuyu Niu Kunming University of Science and Technology KunmingYunnan ProvinceChina Yunnan Key Laboratory of Primate Biomedical Research KunmingYunnan ProvinceChina

The remarkable similarity between non-human primates(NHPs)and humans establishes them as essential models for understanding human biology and diseases,as well as for developing novel therapeutic strategies,thereby providing more comprehensive reference data for clinical *** stem cells such as embryonic stem cells and induced pluripotent stem cells provide unprecedented opportunities for cell therapies against intractable diseases and *** continue to harness the potential of these biotechnological therapies,NHPs are increasingly being employed in preclinical trials,serving as a pivotal tool to evaluate the safety and efficacy of these ***,we review the recent advancements in the fundamental research of stem cells and the progress made in studies involving NHPs.

关键词： non-human primates cell therapy stem cell

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花生红衣中高聚原花青素的水解

生物加工过程 2021年第3期19卷 268-273页

作者：徐旺姚旭王元初史卓尧王建蒋佳乐王海红曹佳凯戴晨曦江苏海洋大学环境与化学工程学院江苏连云港222005

原花青素抗氧化程度受原花青素平均聚合度的影响很大,低聚原花青素的活性明显高于高聚原花青素的活性。从花生红衣提取物中所得到的原花青素相当一部分是以高聚体的形式存在,将高聚体通过水解,变成低聚体,对于增加人体吸收效率和植物的... 详细信息

原花青素抗氧化程度受原花青素平均聚合度的影响很大,低聚原花青素的活性明显高于高聚原花青素的活性。从花生红衣提取物中所得到的原花青素相当一部分是以高聚体的形式存在,将高聚体通过水解,变成低聚体,对于增加人体吸收效率和植物的利用度都有较大作用。以花生红衣原花青素提取物为原料,经水溶解平衡后过滤分离,滤去低聚体,对高聚体原花青素分别使用磷酸、柠檬酸及732型阳离子树脂等为催化剂进行水解。着重研究温度和时间对水解反应的影响,水解后原花青素平均聚合度的测定采用硫酸香草醛法。研究表明,在相同条件下,732型阳离子树脂是最适宜的水解催化剂。通过单因素和正交试验得到优化的水解反应条件:原花青素甲醇溶液与阳离子树脂体积比为2.0∶1、水解温度60℃下,反应15 min的平均聚合度为2.55。

关键词：花生红衣高聚原花青素水解平均聚合度生物资源