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A Small Heat Shock Protein for Rosa chinesis Confers Resistance to a Variety of Stresses in Both Prokaryotic and Eurkaryotic Cells

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A Small Heat Shock Protein for Rosa chinesis Confers Resista...

Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing 1,2,4-Triazolinone Moiety

中国细胞生物学学会第九次会员代表大会暨青年学术大会

作者： Chang-hua Jiang Jin-Lei Shi Jian-Yao Xu,Feng Ming~* (Institute of genetics,state key laboratory of Genetic Engineering,School of Life Science,Fudan University,Shanghai 200433,China)

The Chinese rose(Rosa chinesis)is an important horticultural plant throughout the *** have identify two different varieties(MD and KP)that exhibit differing responses to high *** this study,we have used comparative pr... 详细信息

关键词： Rosa chinesis L. thermotolerance smHSP resistence expression

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Chemical Research in Chinese Universities 2013年第3期29卷 466-472页

作者： LIU zhuo PAN Li LIYong-hong WANG Su-hua LI Zheng-ming state key laboratory of Elemento-Organic Chemistry Institute of Elemento-Organic Chemistry Nankai University Tianjin 300071 P. R. China

A series of new sulfonylureas incorporating 1,2,4-triazolinone moiety was synthesized, which were further bio-assayed for the herbicidal activity against four herbs, representative of monocotyledons and dicotyledons. Some of them exhibited high potency to inhibit the growth of dicotyledons（Bassica napus and Arnaranthus retroflexus） in the pot experiment. Compounds 9a and 9b also displayed an excellent herbicidal activity against Bassica napus at a concentration of 15 g/hectare, which were comparable with commercial triasulfuron.

关键词： Sulfonylurea herbicide Acetohydroxyacid synthetase(AHAS) 1,2,4-Triazolinone derivative Protox Herbicidal activity

Effect of Deformation Temperature on Deformation Mechanism of Fe-6.5Si Alloys with Different Initial Microstructures

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Journal of Iron and Steel Research International 2016年第4期23卷 344-349页

作者： hua-dong FU Yuan-ke MO Long-chao zhuo Zhi-hao zhang Jian-xin XIE Institute for Advanced Materials and Technology University of Science and Technology Beijing School of Materials Science and Engineering Xi'an University of Technology

Deformation behaviors and mechanisms under different temperatures for columnar-grained Fe 6.5Si （mass%） alloys fabricated by directional solidification and equiaxed grained Fe-6.5Si alloy fabricated by forging were comparatively investigated. The results showed that, with increasing the deformation temperature from 300℃ to 500℃, the elongation increased from 2.9% to 30.1% for the equiaxed-grained Fe-6.5Si alloy, while from 6.6% to about 51% for the columnar-grained Fe-6.5Si alloy. The deformation mode of equiaxed-grained Fe 6.5Si alloy trans ferred from nearly negligible plastic deformation to large plastic deformation dominated by dislocation slipping. Comparatively, the deformation mode of the columnar grained alloy transferred from nearly negligible plastic deformation to plastic deformation dominated by the twining, and finally to plastic deformation dominated by dislocation slipping. Meanwhile, compared with the alloy with equiaxed grains, it was found that ultimate tensile strength and elongation could be increased simultaneously, which was ascribed for the twinning deformation in columnar-grained Fe-6.5Si al loy. This work would assist us to further understand the plastic deformation mechanism of Fe-6.5Si alloy and pro vide more clues for high-efficiency production of the alloy.

关键词： Fe-6.5Si alloy deformation behavior microstructure control mechanical property tensile deformation

Effect of Warm Rolling on Micro-deformation Behavior and Mechanical Properties of Columnar-grained Fe-6.5 mass%Si Alloy

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Journal of Iron and Steel Research International 2016年第3期23卷 225-230页

Micro-deformation behavior and mechanical properties of columnar-grained Fe-6.5 mass%Si alloy before and after warm rolling were investigated by means of micro-indentation and three-point bending *** results show that the columnar-grained Fe-6.5mass%Si alloy before warm rolling presents sink-in mode of micro-indentation,while pile-up mode with a number of arc-shaped deformation bands exists in the warm-rolled *** with that of the alloy before warm rolling,the maximum bending fracture stress and maximum bending fracture deflection of the warm-rolled alloy are increased by 96% and 50%,*** different micro-deformation behavior and mechanical properties of the columnar-grained Fe-6.5mass%Si alloy are ascribed to the changes of dislocation density,dislocation configuration and long-range order degree,which significantly improve the room temperature plasticity of the alloy after warm rolling.

关键词： Fe-6.5mass%Si alloy warm rolling micro-deformation mechanical property

Superconductivity in kagome metal ThRu3Si2

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Chinese Physics B 2024年第5期33卷 50-55页

作者：刘艺厉静杨武璋卢佳依曹博雅李华旬柴万力武思祺李佰卓孙云蕾焦文鹤王操许晓峰任之曹光旱 School of Physics Zhejiang University Department of Applied Physics Zhejiang University of Technology School of Science Westlake Institute for Advanced Study Westlake University Department of Physics Shandong University of Technology School of Information and Electrical Engineering Zhejiang University City College Interdisciplinary Center for Quantum Information and State Key Laboratory of Silicon and Advanced Semiconductor MaterialsZhejiang University Collaborative Innovation Centre of Advanced Microstructures Nanjing University

We report the physical properties of ThRu3Si2featured with distorted Ru kagome lattice. The combined experiments of resistivity, magnetization and specific heat reveal bulk superconductivity with Tc= 3.8 K. The specific heat jump and calculated electron–phonon coupling indicate a moderate coupled BCS superconductor. In comparison with LaRu3Si2,the calculated electronic structure in ThRu3Si2shows an electron-doping effect with electron filling lifted from 100 meV below flat bands to 300 meV above it. This explains the lower superconducting transition temperature and weaker electron correlations observed in ThRu3Si2. Our work suggests the Tc and electronic correlations in the kagome superconductor could have an intimate connection with the flat bands.

关键词： superconductivity kagome lattice flat band

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绵羊MYL基因家族的鉴定与组织表达分析

畜牧兽医学报 2024年第4期55卷 1551-1564页

作者：杨杨余乾刘昱成杨华赵卓王立民周平杨庆勇代蓉新疆农垦科学院省部共建绵羊遗传改良与健康养殖国家重点实验室石河子832000 华中农业大学信息学院武汉430070

为了解肌球蛋白轻链(myosin light chain,MYL)基因家族在绵羊中的分子进化关系及表达变化,本研究利用生物信息学方法对绵羊MYL基因家族进行鉴定和系统分析。各选取了3只军垦白肉羊、新疆细毛羊和湖羊成年公羊各组织样品,采用qRT-PCR方... 详细信息

为了解肌球蛋白轻链(myosin light chain,MYL)基因家族在绵羊中的分子进化关系及表达变化,本研究利用生物信息学方法对绵羊MYL基因家族进行鉴定和系统分析。各选取了3只军垦白肉羊、新疆细毛羊和湖羊成年公羊各组织样品,采用qRT-PCR方法验证家族成员MYL1、MYL6B和MYLPF基因的表达情况。结果显示,12个MYL基因分布在9条染色体上,编码由147~211氨基酸组成的亲水性蛋白质,无信号肽和跨膜结构域,二级结构以α-螺旋为主。根据基因结构、保守结构域和基序分布等特征,可以将这些基因家族成员分为3个组。共线性分析结果表明,MYL2和MYL10、MYL2和MYLPF存在片段复制,且这些片段受到较强的选择压力。蛋白互作网络显示MYH10与绵羊MYL家族成员均存在互作关系。MYLs的组织表达模式差异较大,其中MYL1、MYL2、MYL6B和MYLPF在骨骼肌组织中高水平表达。基因克隆测序结果显示,扩增得到目的基因的CDS全长,qRT-PCR结果表明,MYL1、MYL6B和MYLPF在军垦白肉羊肌肉组织中的表达水平显著高于其他组织(P<0.0001),并且在军垦白肉羊骨骼肌中的表达水平显著高于湖羊和细毛羊(P<0.0001)。以上结果为深入研究绵羊MYL基因家族的功能以及优化绵羊肉用性能提供了线索。

关键词：绵羊 MYL 基因家族生物信息学分析基因表达

Effect of confinement on the three-phase equilibrium of water-oil-CO_(2)mixtures in nanopores

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Petroleum Science 2022年第1期19卷 203-210页

作者： Yi-Lei Song Shao-hua Gu Zhao-Jie Song zhuo-Ya zhang Xu-Ya Chang Jia Guo state key laboratory of Petroleum Resources and Prospecting and Unconventional Petroleum Research Institute China University of Petroleum-BeijingBeijing102249China Sinopec Petroleum Exploration and Production Research Institute Beijing100083China

Accurate characterization of fluid phase behavior is an important aspect of CO_(2) enhanced shale oil *** far,however,there has been little discussion about the nanopore confinement effect,including adsorption and capillarity on the phase equilibrium of water-oil-CO_(2) *** this study,an improved three-phase flash algorithm is proposed for calculating the phase behavior of water-oil-gas mixture on the basis of an extended Young-Laplace equation and a newly developed fugacity calculation *** fugacity model can consider the effect of water-oil-gas adsorption on phase equilibrium.A water-Bakken oil-CO_(2) mixture is utilized to verify the accuracy of the flash algorithm and investigate the confinement *** show that the confinement effect promotes the transfer of all components in the vapor phase to other phases,while the transfer of water,CO_(2),and lighter hydrocarbons is more *** leads to a large decrease,a large increase,and a small increase in the mole fraction of the vapor,oleic,and aqueous phases,*** the confinement effect is considered,the density difference of vaporoleic phases decreases,and the interfacial tension of vapor-oleic phases decreases;however,the density difference of vapor-aqueous phases increases,the interfacial tension of vapor-aqueous phases still decreases.

关键词： Three-phase behavior Water-oil-CO_(2)mixtures Nanopore confinement CO_(2)enhanced oil recovery Shale reservoirs

Iron metabolism and arthritis: Exploring connections and therapeutic avenues

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中华医学杂志(英文版) 2024年第14期137卷 1651-1662页

作者： zhuo Dachun Xiao Wenze Tang Yulong Jiang Shuai Geng Chengchun Xie Jiangnan Ma Xiaobei zhang Qing Tang Kunhai Yu Yuexin Bai Lu Zou Hejian Liu Jing Wang Jiucun Department of Rheumatology Shanghai Pudong Hospital Human Phenome Institute Zhangjiang Fudan International Innovation Center Fudan University Shanghai China state key laboratory of Genetic Engineering School of Life Science Fudan University Shanghai China Department of Vascular Surgery Shanghai Pudong Hospital Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling Fudan University Pudong Medical Center Shanghai China Department of Anthropology and Human genetics School of Life Sciences Ministry of Education Key Laboratory of Contemporary Anthropology Fudan University Shanghai China Division of Rheumatology Huashan Hospital State Key Laboratory of Genetic Engineering School of Life Science Fudan University Shanghai China Institute of Rheumatology Immunology and Allergy Allergy and Disease Research Center Fudan University Shanghai China Research Unit of Dissecting the Population genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058) Chinese Academy of Medical Sciences Beijing China

Iron is indispensable for the viablility of nearly all living organisms, and it is imperative for cells, tissues, and organisms to acquire this essential metal sufficiently and maintain its metabolic stability for survival. Disruption of iron homeostasis can lead to the development of various diseases. There is a robust connection between iron metabolism and infection, immunity, inflammation, and aging, suggesting that disorders in iron metabolism may contribute to the pathogenesis of arthritis. Numerous studies have focused on the significant role of iron metabolism in the development of arthritis and its potential for targeted drug therapy. Targeting iron metabolism offers a promising approach for individualized treatment of arthritis. Therefore, this review aimed to investigate the mechanisms by which the body maintains iron metabolism and the impacts of iron and iron metabolism disorders on arthritis. Furthermore, this review aimed to identify potential therapeutic targets and active substances related to iron metabolism, which could provide promising research directions in this field.

关键词： Iron metabolism Arthritis Inflammation Immunity Rheumatoid arthritis Psoriatic arthritis Gouty arthritis

集胞蓝藻PCC6803含疏水亚基的NAD(P)H脱氢酶亚复合体的分离

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生物化学与生物物理学报 2003年第8期35卷 723-727页

作者：邓勇叶济宇米华玲沈允钢中国科学院上海生命科学研究院植物生理生态研究所、植物分子遗传国家重点实验室中国科学院上海生命科学研究院植物生理生态研究所、植物分子遗传国家重点实验室上海200032

利用离子交换与凝胶过滤层析 ,从n dodecylβ D maltoside(DM)处理的集胞蓝藻SynechocystisPCC6 80 3细胞粗提液中 ,首次分离到两个包含NDH疏水亚基NdhA的亚复合体。酶活性分析表明 ,分离到的NDH亚复合体具有NADPH 氮蓝四唑 (NBT)氧化... 详细信息

利用离子交换与凝胶过滤层析 ,从n dodecylβ D maltoside(DM)处理的集胞蓝藻SynechocystisPCC6 80 3细胞粗提液中 ,首次分离到两个包含NDH疏水亚基NdhA的亚复合体。酶活性分析表明 ,分离到的NDH亚复合体具有NADPH 氮蓝四唑 (NBT)氧化还原酶活性 ,以NADPH为电子供体可以还原铁氰化钾、二溴百里香醌 (DBMIB)、二氯酚靛酚 (DCPIP)、duroquinone以及UQ 0等质醌类电子受体。

关键词：集胞蓝藻 NAD(P)H脱氢酶疏水亚基