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华夏医学 1999年第6期12卷 677-678页

作者：王瑞芝朱玉昆北京市西城区展览路医院内科北京市100044

冠状动脉造影术是诊断冠心病最直观、最可靠的方法,同时可了解冠脉病变部位、范围及程度,为选择合理治疗和判断预后提供了决定性依据[1,2].现将我院1995年8月至1997年11月进行的64例冠脉造影病例分析如下.

关键词：冠心病冠状动脉造影术诊断

An improved social force model (ISFM)-based crowd evacuation simulation method in virtual reality with a subway fire as a case study

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International Journal of Digital Earth 2023年第1期16卷 1186-1204页

作者： Jinbin Zhang Jun zhu Pei Dang Jianlin Wu Yuxuan Zhou Weilian Li Lin Fu yukun Guo Jigang You Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduPeople’s Republic of China Institute of Geodesy and Geoinformation University of BonnBonnGermany School of Engineering and Geomatics Southwest Petroleum UniversityChengduPeople’s Republic of China

Crowd evacuation simulation using virtual reality(VR)is significant for digital emergency response ***,existing evacuation simulation studies suffer from poor adaptation to complex environments,inefficient evacuations,and poor simulation effects and do not fully consider the impacts of specific disaster environments on crowd *** more realistically express the crowd evacuation results obtained under the influence offire environments and the subjective consciousness of pedestrians in subway stations,we designed a dynamic pedestrian evacuation path planning method under multiple constraints,analysed the influences of an‘environmental role’and a‘subjective initiative’on crowd evacuation,established an improved social force model(ISFM)-based crowd evacuation simulation method in VR,developed a prototype system and conducted experimental *** experimental results show that the crowd evacuation time of the ISFM is affected by the disaster *** simulation experiments without disaster scenarios,the improved model’s crowd evacuation efficiency improved by averages of 12.53%and 15.37%over the commercial Pathfinder software and the original social force model,*** method described herein can effectively support real-time VR crowd evacuation simulation under multiexit and multifloor conditions and can provide technical support for emergency evacuation learning and management decision analyses involving subwayfires.

关键词： Subway stationfire improved social force model crowd evacuation simulation virtual reality path planning

基于AHP和熵权法的航空维修差错致因因素分析

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安全 2024年第9期45卷 47-52页

作者：张玎孙正楠朱做涛张宇坤孔光明海军航空大学青岛校区山东青岛266041 海军第91049部队山东青岛266100

为准确识别航空维修差错重要致因因素,提升预防措施制定的针对性,基于由人员、硬件、软件以及环境组成的SHEL模型构建了航空维修差错致因评价指标体系,以海军航空兵某部队航空维修为例采用层次分析法(AHP)和熵权法对各指标重要度进行分... 详细信息

为准确识别航空维修差错重要致因因素,提升预防措施制定的针对性,基于由人员、硬件、软件以及环境组成的SHEL模型构建了航空维修差错致因评价指标体系,以海军航空兵某部队航空维修为例采用层次分析法(AHP)和熵权法对各指标重要度进行分析,结合两者的分析结果,提出预防措施。分析结果显示:层次分析法获得的主要致因因素为人际关系和交际能力、信息平台、生理/心理素质、工作负荷和人员培训;熵权法获得的主要致因因素为飞机结构、人员培训、人际关系和交际能力、维修装备与设备以及知识与技能;提出该部队可通过信息化等手段强化过程记录以确保工作交接完备等措施。

关键词：航空维修差错致因因素分析 SHEL模型层次分析法(AHP) 熵权法

Essential role of Msx1 in regulating anterior-posterior patterning of the secondary palate in mice

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Journal of Genetics and Genomics 2022年第1期49卷 63-73页

作者： Shicheng zhu Hanjing Song Liangjun Zhong Suman Huo yukun Fang Wanxin Zhao Xueqin Yang Zhong-Min Dai Rui He Mengsheng Qiu Zunyi Zhang Xiao-Jing zhu Institute of Life Sciences College of Life and Environmental SciencesKey Laboratory of Mammalian Organogenesis and RegenerationHangzhou Normal UniversityHangzhouZhejiang 311121China The Affiliated Hospital Hangzhou Normal UniversityHangzhouZhejiang 310015China

Development of the secondary palate displays molecular heterogeneity along the anterior-posterior axis;however, the underlying molecular mechanism remains largely unknown. MSX1 is an anteriorly expressed transcription repressor required for palate development. Here, we investigate the role of Msx1 in regional patterning of the secondary palate. The Wnt1-Cre-mediated expression of Msx1(Rosa Msx1^(Wnt1-Cre))throughout the palatal mesenchyme leads to cleft palate in mice, associated with aberrant cell proliferation and cell death. Osteogenic patterning of the hard palate in Rosa Msx1^(Wnt1-Cre)mice is severely impaired, as revealed by a marked reduction in palatine bone formation and decreased expression of the osteogenic regulator Sp7. Overexpression and knockout of Msx1 in mice show that the transcription repressor promotes the expression of the anterior palate-specific Alx1 but represses the expression of the medialposterior palate genes Barx1, Meox2, and Tbx22. Furthermore, Tbx22 constitutes a direct Msx1 target gene in the secondary palate, suggesting that Msx1 can directly repress the expression of medial-posterior specific genes. Finally, we determine that Sp7 is downstream of Tbx22 in palatal mesenchymal cells,suggesting that a Msx1/Tbx22/Sp7 axis participates in the regulation of palate development. Our findings unveil a novel role for Msx1 in regulating the anterior-posterior growth and patterning of the secondary palate.

关键词： Cleft palate Conditional knock-in Mouse model Msx1 Organ development

贯彻落实党的二十大人才强国和乡村振兴战略——以专业技能竞赛为抓手提升园艺专业人才培养质量

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科技资讯 2024年第19期22卷 4-9,78页

作者：王玉昆蒋园园朱云娜肖艳辉王斌广东省粤北食药资源保护与利用重点实验室(韶关学院生物与农业学院) 广东韶关512005

党的二十大报告指出,要全面推进乡村振兴战略,人才是最关键的因素。地方涉农高等院校是培养乡村振兴所需高素质和高技能人才的主阵地,专业技能竞赛是提高人才培养质量的重要手段。以韶关学院园艺专业为例,介绍其通过专业技能竞赛贯彻落... 详细信息

党的二十大报告指出,要全面推进乡村振兴战略,人才是最关键的因素。地方涉农高等院校是培养乡村振兴所需高素质和高技能人才的主阵地,专业技能竞赛是提高人才培养质量的重要手段。以韶关学院园艺专业为例,介绍其通过专业技能竞赛贯彻落实党的二十大人才强国和乡村振兴战略的举措和成效,着重探讨专业技能竞赛对园艺专业学生的综合素质、专业技能、实践能力,以及教师的教育教学能力等方面的促进作用,以期为同类型地方普通本科院校园艺专业的实践教育和教育综合改革提供参考,有效提高地方本科院校园艺专业的人才培养质量,助力乡村振兴战略。

关键词：党的二十大精神人才强国乡村振兴人才培养专业技能竞赛

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HL-1装置中的等离子体与器壁相互作用

核聚变与等离子体物理 1988年第2期 65-72页

作者：朱毓坤严东海王明旭张年满唐素筠孙立李国栋西南物理研究所西南物理研究所四川乐山

本文对HL-1装置欧姆加热放电时,等离子体—器壁相互作用进行了实验研究。质谱分析定性地指出,主要气相杂质H2O来自零级表面化学反应,CH4来自多步骤合成表面化学反应,CO（CO2）则来自碰撞表面化学反应。收集探针的表面分析显示出,Mo,Cr... 详细信息

本文对HL-1装置欧姆加热放电时,等离子体—器壁相互作用进行了实验研究。质谱分析定性地指出,主要气相杂质H2O来自零级表面化学反应,CH4来自多步骤合成表面化学反应,CO（CO2）则来自碰撞表面化学反应。收集探针的表面分析显示出,Mo,Cr和Ni等为主要的重杂质;蒙特卡罗模拟分析给出了氢粒子注入硅探针的特征深度和其动力温度的拟合直线关系式。

关键词：质谱收集探针二次离子质谱蒙特卡罗分析

A terahertz on-chip InP-based power combiner designed using coupled-grounded coplanar waveguide lines

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Chinese Physics B 2021年第12期30卷 329-333页

作者： Huali zhu Yong Zhang Kun Qu Haomiao Wei yukun Li Yuehang Xu Ruimin Xu School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

This article presents the design and performance of a terahertz on-chip coupled-grounded coplanar waveguide(GCPW)power combiner using a 50μm-thick InP *** proposed topology uses two coupled-GCPW lines at the end of the input port to substitute two quarter-wavelength GCPW lines,which is different from the conventional Wilkinson power combiner and can availably minimize the coverage *** to the results obtained,for the frequency range of 210-250 GHz,the insertion losses for each two-way combiner and four-way combiner were lower than 1.05 dB and1.35 dB,respectively,and the in-band return losses were better than 11 ***,the proposed on-chip GCPW-based combiners achieved a compromise in low-loss,broadband,and small-size,which can find wide applications in terahertz bands,such as power amplifiers and signal distribution networks.

关键词： coupled-GCPW InP technology terahertz monolithic integrated circuits(TMICs) Wilkinson power combiner

Web 3.0时代下人工智能赋能体育赛事发展的价值、挑战与应用策略

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当代体育科技 2024年第21期14卷 72-75页

作者：王宇坤丁杰陈根桂超朱磊何晓晗邓钰臻曲阜师范大学研究生部山东济宁272000 国家体育总局运动医学研究所北京100061 山东第一医科大学运动医学与康复学院山东济南250000

在“十四五”规划提出加快数字发展,建设数字中国的背景下,人工智能数字技术在体育赛事领域的应用已成为当今发展的热点之一。然而,随着科技快速的发展,人工智能数字技术在带来利益的同时,也逐渐暴露出了弊端,出现了隐私泄露、垄断资源... 详细信息

在“十四五”规划提出加快数字发展,建设数字中国的背景下,人工智能数字技术在体育赛事领域的应用已成为当今发展的热点之一。然而,随着科技快速的发展,人工智能数字技术在带来利益的同时,也逐渐暴露出了弊端,出现了隐私泄露、垄断资源等问题。现如今,Web 3.0被称为能够有效解决这些问题的新一代互联网,现今,我国正处于Web 3.0发展的初期,因此,通过文献资料法、逻辑分析法等研究方法,探究Web3.0时代下人工智能数字技术对体育赛事发展的价值与挑战,并提出一些应对策略,旨在为体育赛事可持续发展提供参考和支持。

关键词：人工智能新一代互联网体育赛事数字化

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香蕉ADA1家族成员鉴定及其在生物和非生物胁迫下的表达分析

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生物工程学报 2024年第1期40卷 190-210页

作者：赵琪琪任纹慧朱慧菲吴秋桢张春渝许小琼罗彬彬黄玉吉陈裕坤林玉玲赖钟雄福建农林大学园艺植物生物工程研究所福建福州350002

Spt-Ada-Gcn5-乙酰转移酶(Spt-Ada-Gcn5-acetyltransferase,SAGA)是高度保守的辅助转录起始复合物,转录接头蛋白-激活的改变/缺失亚基1(alteration/deficiency in activation 1,ADA1),也称作组蛋白H2A功能互作因子1(histone H2A functional interactor 1,HFI1),它是SAGA核心模块中的一个亚基,在植物的生长发育和抗逆性方面发挥着重要的作用。为了解香蕉ADA1的分子特性,本研究基于香蕉基因组数据库,对香蕉ADA1基因家族成员进行鉴定,分析其基本理化性质、系统进化、选择压力、启动子顺式作用元件及生物与非生物胁迫下的表达等。结果显示,香蕉A、B及阿宽蕉基因组中分别有10、6、7个ADA1家族成员;成员均为不稳定的亲水性蛋白,均保守地含有SAGA-Tad1结构域,MaADA1和MbADA1均可与SAGA核心模块中的SAGA相关因子11(SAGA-associated factor 11,Sgf11)互作;系统发育显示香蕉ADA1基因家族成员可划分为3个亚族,进化过程中大多受纯化选择;香蕉ADA1基因家族成员的基因结构差异性较大;香蕉ADA1基因家族成员含有多个响应激素的作用元件;MaADA1-1可能对香蕉在低温胁迫下的抗性起着重要的作用,MaADA1均响应香蕉枯萎病菌胁迫。本研究表明,ADA1基因家族成员在香蕉中高度保守,并可能响应生物与非生物胁迫。

关键词：香蕉 Spt-Ada-Gcn5-乙酰转移酶激活的改变/缺失亚基1 全基因组鉴定胁迫

A dynamic holographic modelling method of digital twin scenes for bridge construction

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International Journal of Digital Earth 2023年第1期16卷 2404-2425页

作者： Jianlin Wu Jun zhu Jinbin Zhang Pei Dang Weilian Li yukun Guo Lin Fu Jianbo Lai Jigang You YaKun Xie Ce Liang Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduPeople’s Republic of China Institute of Geodesy and Geoinformation University of BonnBonnGermany School of Engineering and Geomatics Southwest Petroleum UniversityChengduPeople’s Republic of China Institute of Computing Technology China Academy of Railway Sciences CoLtdBeijingPeople’s Republic of China

Holographic projection technology can provide a more intuitive and efficient visualization effect for a digital twin bridge construction ***,pre-rendering methods in the existing research work are usually used to implement holographic visualization,which is static *** above-mentioned methods for static display have many shortcomings,such as poor adaptability,low rendering efficiency and lack of real-time.A dynamic holographic modelling approach is proposed for the augmented visualization of digital twin scenes for bridge ***,a dynamic segmentation algorithm with adaptive screen size was designed to high-efficiently generate holographic ***,a motion blur control method was designed to improve the rendering efficiency of holographic scenes according to human visual ***,a prototype system was developed,and the corresponding experimental analysis was *** experimental results show that the method proposed in this article can support adaptive screen size image segmentation and real-time generation of holographic scenes for bridge *** amount of scene data can be reduced to more than 30%,which significantly improves rendering efficiency and reduces glare.

关键词： Bridge construction Digital twins Holographic scene Adaptive segmentation Rendering optimization