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南京医科大学学报（自然科学版） 2007年第10期27卷 1155-1155页

作者： Luo, C. x. j.ang, j. Zhou, Q. G. zhu, x. j. Wang, W. Zhang, Z. j. Han, x. zhu, D. Y. Nanj.ng Med Univ Sch Pharm Dept Pharmacol. Nanjing Peoples R China. Chinese Acad Sci Shanghai Inst Biol Sci Inst Neurosci Shanghai Peoples R China. Nanj.ng Med Univ Lab Mammalian Genes Nanjing Peoples R China.

Neuronal nitric ox.de synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis

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南京医科大学学报(自然科学版) 2008年第1期 4-4页

作者： Zhou,Q. G. Hu,Y. Hua,Y. Hu,M. Luo,C. x. Han,x. zhu,x. j. Wang,B. x.,j. S. zhu,D. Y Nanj.ng Med Univ,Sch Pharm,Dept Pharmacol,Nanj.ng 210029,Peoples R China. Nanj.ng Med Univ,Key Lab Mammalian Genes,Nanj.ng,Peoples R China.

Increasing evidence suggests that depression may be associated with a lack of hippocampal neurogenesis. It is well established that neuronal nitric ox.de synthase(nNOS)-derived NO ex.rts a negative control on the hippocampal neurogenesis. Using genetic and pharmacological methods,we investigated the roles of nNOS in depression induced by chronic mild stress(CMS) in mice. Hippocampal nNOS over-ex.ression was first observed 4 days and remained elevated 21 and 56 days after ex.osure to CMS. The mice ex.osed to CMS ex.ibited behavioral changes typical of depression,and impaired neurogenesis in the hippocampus. The CMS-induced behavioral despair and hippocampal neurogenesis impairment were prevented and reversed in the null mutant mice lacking nNOS gene(nNOS-/-) and in the mice receiving nNOS inhibitor. Disrupting hippocampal neurogenesis blocked the antidepressant effect of nNOS inhibition. Moreover,nNOS-/-mice ex.ibited antidepressant-like properties. Our findings suggest that nNOS over-ex.ression in the hippocampus is essential for chronic stress-induced depression and inhibiting nNOS signaling in brain may represent a novel approach for the treatment of depressive disorders.

关键词： depression hippocampal neurogenesis neuronal nitric ox.de synthase nitric ox.de stress element-binding protein chronic mild stress ischemia stimulates neurogenesis rat paraventricular nucleus adult dentate gyrus antidepressant-like cell-proliferation anx.olytic-like prefrontal cortex progenitor cells

A mini review： Shape memory polymers for biomedica applications

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Frontiers of Chemical Science and Engineering 2017年第2期11卷 143-153页

作者： Kaoj.n Wang Satu Strandman x. x. zhu Departement de Chimie Universite de Montreal Montreal QC H3C 3J7 Canada

Shape memory polymers （SMPs） are smart materials that can change their shape in a pre-defined manner under a stimulus. The shape memory functionality has gained considerable interest for biomedical applications, which require materials that are biocompatible and sometimes biodegradable. There is a need for SMPs that are prepared from renewable sources to be used as substitutes for conventional SMPs. In this paper, advances in SMPs based on synthetic monomers and bio-compounds are discussed. Materials designed for biomedical applica- tions are highlighted.

关键词： shape memory polymer biodegradability biocompatibility biomedical application bile acids

Impacts of the annual cycle of background SST in the tropical Pacific on the phase and amplitude of ENSO

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 12-17页

作者： Song j.ang Congwen zhu Ning j.ang State Key Laboratory of Severe Weather(LASW) Chinese Academy of Meteorological SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina

The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific ex.ibits an antisymmetric mode,which ex.lains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of *** on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bj.rknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual *** magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity *** reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.

关键词： Annual cycle SST anomaly Antisymmetric mode ENSO

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Satellite remote sensing reveals overwhelming recovery of forest from disturbances in Asia

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 46-51页

作者： Yiying zhu Hesong Wang Anzhi Zhang School of Ecology and Nature Conservation Beijing Forestry UniversityBeijingChina Key Laboratory of Regional Climate and Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Forestry and Landscape Architecture Xinjiang Agricultural UniversityUrumqiChina

Forest ecosystems play key roles in mitigating human-induced climate change through enhanced carbon uptake;however,frequently occurring climate ex.remes and human activities have considerably threatened the stability of *** the same time,detailed accounts of disturbances and forest responses are not yet well quantified in *** study employed the Breaks For Additive Seasonal and Trend method-an abrupt-change detection method-to analyze the Enhanced Vegetation Index.time series in East Asia,South Asia,and Southeast *** approach allowed us to detect forest disturbance and quantify the resilience after *** showed that 20%of forests ex.erienced disturbance with an increasing trend from 2000 to 2022,and Southeast Asian countries were more severely affected by ***,95%of forests had robust resilience and could recover from disturbance within a few *** resilience of forests suffering from greater magnitude of disturbance tended to be stronger than forests with lower disturbance *** summary,this study investigated the resilience of forests across the low and middle latitudes of Asia over the past two *** authors found that most forests ex.ibited good resilience after disturbance and about two-thirds had recovered to a better state in *** findings of this study underscore the complex.relationship between disturbance and resilience,contributing to comprehension of forest resilience through satellite remote sensing.

关键词： Forest ecosystem Enhanced vegetation index Breaks for additive seasonal and trend method Disturbance Resilience

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EFFECTS OF GAS TYPE AND TEMPERATURE ON FINE PARTICLE FLUIDIZATION

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China Particuology 2006年第3期4卷 114-121页

作者： Chunbao x. j.-x. zhu Department of Chemical Engineering Lakehead University Thunder Bay Ontario P7B 5E1 Canada powder Technology Research Centre Department of Chemical & Biochemical Engineering The University of Western Ontario London Ontario N6A 5B9 Canada

The influence of gas type （helium and argon） and bed temperature （77-473 K） on the fluidization behaviour of Geldart groups C and A particles was investigated. For both types of particles tested, i.e., Al2O3 （4.8μm） and glass beads （39 μm）, the fluidization quality in different gases shows the following priority sequence： Ar 〉 He. In the same gaseous atmosphere, the particles when fluidized at an elevated temperature usually show larger bed voidages, higher bed pressure drops, and a lower Umf for the group A powder, all indicating an enhancement in fluidization quality. Possible mechanisms governing the operations of gas type and temperature in influencing the fluidization behaviours of fine particles have been discussed with respect to the changes in both gas properties and interparticle forces （on the basis of the London-van der Waals theory）. Gas viscosity （varying significantly with gas-type and temperature） proves to be the key parameter that influences the bed pressure drops and Umf in fluidization of fine particles, while the interparticle forces （also varying with gas-type and temperature） may play an important role in fine-particle fluidization by affecting the ex.ansion behaviour of the particle-bed.

关键词： fluidization fine particles gas type temperature interparticle forces

GAS-SOLIDS FLOW BEHAVIOR WITH A GAS VELOCITY CLOSE TO ZERO

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China Particuology 2006年第3期4卷 167-177页

作者： H. Zhang j.-x. zhu Department of Chemical Engineering University of Western Ontario London Ontario Canada N6A 5B9 Canada

In a 9.3 m high and 0.10 m i.d. gas-solids downflow fluidized bed （downer）, the radial and ax.al distributions of the local solids holdups and particle velocities along the downer column were measured with the superficial gas velocity set to zero. A unique gas-solids flow structure was found in the downer system with zero gas velocity, which is completely different from that under conditions with higher gas velocities, in terms of its radial and ax.al flow structures as well as its micro flow structure. The gas-solids flow pattern under zero gas velocity conditions, together with that under low gas velocity conditions, can be considered as a special regime which differs from that under higher gas velocity conditions. According to the hydrodynamic properties of the two regimes, they can be named the ＂dense annulus＂ regime for the flow pattern under zero or low gas velocity conditions and the ＂dense core＂ regime for that under higher gas velocity conditions.

关键词： downer reactor gas-solids cocurrent downflow fluidized bed hydrodynamics flow development particle velocity solids holdup solids flux flow regime

Glucose-sensitivity of core-shell microspheres and their crystalline colloidal arrays

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Science China Chemistry 2013年第1期56卷 65-70页

作者： BAZIN Gwénaёlle zhu j.lian x. x. Département de Chimie Université de MontréalC.P.6128Succursale Centre-villeMontréalQuébec H3C 3J7Canada

Thermoresponsive core-shell microspheres are prepared and functionalized with 3-aminophenylboronic acid to make them responsive to *** volume phase transition of the resulting particles is shifted to a lower temperature and a clear swelling is caused by the presence of *** particles after the functionalization preserved their capability to form crystalline colloidal *** changes of their properties may be used in the design of glucose sensors.

关键词： core-shellmicrospheres thermo-sensitivity crystalline colloidal arrays glucose sensors

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Low-cost and fluoride-free synthesis of MFI zeolite nanosheets with enhanced stability for benzene alkylation with ethanol

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j.urnal of Energy Chemistry 2025年第1期100卷 458-468页

作者： Peng zhu Cun Liu Yiren Yu Guoshu Gao Yumeng Zhao x.ongfu Zhang Guodong Liu Guohui Yang State Key Laboratory of Fine Chemicals School of Chemical Engineering Dalian University of Technology State Key Laboratory of Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences

Zeolite nanosheets with a short b-ax.s thickness are highly desirable in lots of catalytic reactions due to their reduced diffusion resistance. Nevertheless, conventional synthesis methods usually require ex.ensive structure-directing agents(SDAs), pricey raw materials, and eco-unfriendly fluorine-containing additives. Here, we contributed a cost-effective and fluoride-free synthesis method for synthesizing high-quality MFI zeolite nanosheets through a Silicalite-1(Sil-1) seed suspension and urea cooperative strategy, only with inex.ensive colloidal silica as the Si source. Our approach was effective for synthesizing both Sil-1 and aluminum-containing ZSM-5 nanosheets. By optimizing key synthesis parameters,including seed aging time, seed quantity, and urea concentration, we achieved precise control over the crystal face aspect ratio and b-ax.s thickness. We also revealed a non-classical oriented nanosheet growth mechanism, where Sil-1 seeds induced the formation of quasi-ordered precursor particles, and the(010)crystal planes of these particles facilitated urea adsorption, thereby promoting c-ax.s-oriented *** obtained ZSM-5 nanosheets ex.ibited ex.eptional catalytic performance in the benzene alkylation with ethanol, maintaining stability for over 500 h, which is 5 times longer than traditional ZSM-5 catalysts. Furthermore, large-scale production of ZSM-5 nanosheets was successfully carried out in a 3 L highpressure autoclave, yielding samples consistent with those from laboratory-scale synthesis. This work marks a significant step forward in the sustainable and efficient production of MFI nanosheets using inex.ensive and environmentally friendly raw materials, offering the broad applicability in catalysis.

关键词： Aspect ratio

Thermal stability of nanograins with grain boundary relax.tion in microalloyed Cu-Sb and Cu-Fe

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j.urnal of Materials Science & Technology 2023年第24期155卷 66-71页

作者： R.j. zhu x.Zhou x.Y. Li Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China School of Materials Science and Engineering University of Science and Technology of China Shenyang 110016 China

Grain refinement into nanoscale significantly enhances the strength and hardness of metallic materials but generally reduces the thermal stability by the introduced strong tendency for grain boundary(GB)*** nanograins through GB relax.tion had been proven as an effective way in several metals recently when the grain size is below a critical ***,we discovered that the abnormally enhanced thermal stability induced by GB relax.tion can be realized in 0.5%Sb or Fe doped Cu,similar to that in pure *** observed critical grain sizes for GB relax.tion in the two Cu alloys are almost the same as pure ***,the GB relax.tion effect on thermal stability is kind of suppressed compared to pure Cu with similar grain sizes because of the segregation/precipitation of Sb/Fe during the annealing process,which accelerates the detwinning and the failure of relax.d GBs.

关键词： Thermal stability Grain boundary relax.tion Nanograined Cu alloy Segregation Precipitate