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O_(2)-generating multifunctional polymeric micelles for highly efficient and selective photodynamic-photothermal therapy in melanoma

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Chinese Chemical Letters 2024年第7期35卷 394-399页

作者： Yu Qin Mingyang Huang Chenlu Huang Hannah LPerry Linhua Zhang Dunwan zhu Tianjin Key Laboratory of Biomedical Materials Key Laboratory of Biomaterials and Nanotechnology for Cancer ImmunotherapyInstitute of Biomedical EngineeringChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300192China Molecular Sciences Research Hub Department of ChemistryWhite City CampusImperial College LondonLondon W120BZUnited Kingdom

Photothermal therapy(PTT)and photodynamic therapy(PDT)have received tremendous attention owing to their great potential for tumor ***,two main issues hamper the antitumor performance of PDT:overexpression of glutathione(GSH)in tumors,which consumes PDT-induced reactive oxygen species(ROS),and hypoxia within the tumor *** drawbacks of PTT include uneven temperature distribution and the upregulation of the heat-shock proteins in tumors,both of which result in ineffective *** address these issues,a MnO_(2)doped nano-delivery system(HTIM-PMs)was synthesized by one-step self-assembly of disulfide bond bridged copolymers for indocyanine green(ICG)and MnO_(2)*** surface of polymeric micelles was layered with hyaluronan(HA)and transactivator(TAT)peptides to improve active targeting and increase cell *** internalization,HTIM-PMs showed responsiveness to the tumor microenvironment(acid pH,high glutathione,high H_(2)O_(2)).Breaking the disulfide bond reduced the intratumoral GSH level and simultaneously released the MnO_(2)and *** released MnO_(2)further reduced the GSH level and promoted O_(2)generation,thus enhancing the PDT *** PTT-mediated hyperthermia accelerated blood flow,which is beneficial for O_(2)distribution,and promotes ROS *** PTT-mediated adjuvant effects further overcame the limitations of PDT and the robust PDT effect in turn compensated for the deficiency of *** promising platform exhibited a significant improvement in the PTT-PDT cancer treatment strategy compared to previously reported nanostructures.

关键词： Photodynamic therapy Photothermal therapy Oxygen generating One-step self-assembly Stimuli-responsive nanoparticles

A visual analysis approach for data imputation via multi-party tabular data correlation strategies

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Frontiers of Information Technology & Electronic Engineering 2024年第3期25卷 398-414页

作者： Haiyang zhu Dongming HAN Jiacheng PAN Yating WEI Yingchaojie FENG Luoxuan WENG Ketian MAO Yuankai XING Jianshu LV Qiucheng WAN Wei CHEN The State Key Lab of CAD&CG Zhejiang UniversityHangzhou 310058China Wuchan Zhongda Digital Technology Co. Ltd.Hangzhou 310020China Zhejiang Metals and Materials Co. Ltd.Hangzhou 310005China

Data imputation is an essential pre-processing task for data governance,aimed at filling in incomplete ***,conventional data imputation methods can only partly alleviate data incompleteness using isolated tabular data,and they fail to achieve the best balance between accuracy and *** this paper,we present a novel visual analysis approach for data *** develop a multi-party tabular data association strategy that uses intelligent algorithms to identify similar columns and establish column correlations across multiple ***,we perform the initial imputation of incomplete data using correlated data entries from other ***,we develop a visual analysis system to refine data imputation *** interactive system combines the multi-party data imputation approach with expert knowledge,allowing for a better understanding of the relational structure of the *** significantly enhances the accuracy and eficiency of data imputation,thereby enhancing the quality of data governance and the intrinsic value of data *** validation and user surveys demonstrate that this method supports users in verifying and judging the associated columns and similar rows using theirdomain knowledge.

关键词： Data governance Data incompleteness Data imputation Data visualization Interactive visual analysis

Rare earth element-modified MOF materials:synthesis and photocatalytic applications in environmental remediation

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Rare Metals 2024年第4期43卷 1390-1406页

作者： Shu-Kun Le Qi-Jie Jin Jia-Ao Han Hua-Cong Zhou Quan-Sheng Liu Fu Yang Jie Miao Pei-Pei Liu Cheng-Zhang zhu Hai-Tao Xu Inner Mongolia Key Laboratory of High-Value Functional Utilization of Low Rank Carbon Resources Chemical Engineering CollegeInner Mongolia University of TechnologyHohhot010050China School of Environmental Science and Engineering Nanjing Tech UniversityNanjing210009China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang212100China Institut National de la Recherche Scientifique-Énergie Matériaux et Télécommunications MontrealQCJ3X 1P7Canada

Metal-organic framework-like materials(MOFs)have been developed in the fields of photocatalysis for their excellent optical properties and physicochemical properties,including environmental remediation,CO_(2)photoreduction,water splitting,and so *** their important roles in various fields,rare earth elements have received growing interests from *** MOFs with rare earth elements for modification allows broadening the absorption spectrum,while the active electrons on their empty 4f orbitals can act as traps to capture photoexcited carriers to inhibit the recombination of electron-hole pairs,thus promoting photocatalytic ***,rare earth elements modified MOFs provide an attractive way to achieve their high value *** this mini-review,the synthesis of rare earth element-modified MOFs photocatalysts and corresponding applications in the removal of antibiotics,CO_(2)reduction,and hydrogen production are constructively summarized and ***,the latest advancements and current difficulties of these materials as well as the application prospects are also provided.

关键词： Rare earth metals MOFs Photocatalytic CO_(2) reduction Environmental remediation Water splitting

High-performance carbon-electrode-based self-powered optoelectronic synaptic devices

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Science China(Information Sciences) 2024年第5期67卷 339-340页

作者： Wen HUANG Xuwen XIA Huixing ZHANG Tenglong GUO Pengjie HANG Bin LI Jiawei TANG Biao LI Chen zhu Lei WANG Deren YANG Xuegong YU Xing'ao LI Jiangsu Provincial Engineering Research Center of Low Dimensional Physics and New Energy & School of Science Nanjing University of Posts and Telecommunications College of Integrated Circuit Science and Engineering Nanjing University of Posts and Telecommunications State Key Laboratory of Silicon and Advanced Semiconductor Materials Zhejiang University

A two-terminal self-powered optoelectronic structure could mimic synaptic functions of a human brain synapse unit(Figure 1(a)) based on the photovoltaic effects [1], demonstrating the potential for decreasing energy consumption for future computing. However, current self-powered optoelectronic synaptic devices face issues of stability and cost,which mainly arise from noble metal electrodes and independent hole transport layers used in these structures. Substituting low-cost carbon for these metal electrodes and carrier transport layers may promise to solve these challenges.

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急性肾功能衰竭的中医药治疗概况

上海中医药大学学报 2000年第2期14卷 63-63,F003页

作者：朱戎胥晓芳上海市龙华医院上海200032 上海市曙光医院上海200021

从近年来中医药治疗急性肾功能衰竭的文献报道看 ,中医药治疗对各种年龄、不同病因。

关键词：急性肾功能衰竭中医药疗法 EHF

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川西坳陷新场气田成藏环境的划分及识别标志

石油实验地质 2001年第2期23卷 174-177页

作者：朱彤叶军王胜中国石化新星石油公司西南石油局研究院四川成都610081

新场气田是川西坳陷中最具规模的典型的多层含气、多类型气藏叠置而成的复杂气田。通过三维地震解释成果的精细描述 ,依据须家河组超压气源的压力分带、气水赋存状态以及所建立和预测的 6类气藏类型 ,在提出了“成藏环境”这一多因素综... 详细信息

新场气田是川西坳陷中最具规模的典型的多层含气、多类型气藏叠置而成的复杂气田。通过三维地震解释成果的精细描述 ,依据须家河组超压气源的压力分带、气水赋存状态以及所建立和预测的 6类气藏类型 ,在提出了“成藏环境”这一多因素综合性概念的基础上 ,作者划分出新场气田 5种不同成藏机制的成藏环境类型 ,并对各成藏环境的成藏条件和主控因素进行了分析 ,确定了各成藏环境的识别标志。

关键词：识别标志主控因素成藏条件成藏环境新场气田川西坳陷

Brillouin Klein space and half-turn space in three-dimensional acoustic crystals

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Science Bulletin 2024年第13期69卷 2050-2058页

作者： Zhenxiao zhu Linyun Yang Jien Wu Yan Meng Xiang Xi Bei Yan Jingming Chen Jiuyang Lu Xueqin Huang Weiyin Deng Ce Shang Perry Ping Shum Yihao Yang Hongsheng Chen Kexin Xiang Gui-Geng Liu Zhengyou Liu Zhen Gao State Key Laboratory of Optical Fiber and Cable Manufacture Technology Department of Electronic and Electrical EngineeringSouthern University of Science and TechnologyShenzhen 518055China School of Physics and Optoelectronics South China University of TechnologyGuangzhou 510640China Key Laboratory of Artificial Micro-and Nanostructures of Ministry of Education and School of Physics and Technology Wuhan UniversityWuhan 430072China King Abdullah University of Science and Technology(KAUST) Physical Science and Engineering Division(PSE)Thuwal 23955-6900Saudi Arabia Interdisciplinary Center for Quantum Information State Key Laboratory of Modern Optical InstrumentationZJU-Hangzhou Global Science and Technology Innovation CenterCollege of Information Science and Electronic EngineeringZJU-UIUC InstituteZhejiang UniversityHangzhou 310027China Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingapore 637371Singapore Institute for Advanced Studies Wuhan UniversityWuhan 430072China

The Bloch band theory and Brillouin zone(bz)that characterize wave-like behaviors in periodic mediums are two cornerstones of contemporary physics,ranging from condensed matter to topological *** theoretical breakthrough revealed that,under the projective symmetry algebra enforced by artificial gauge fields,the usual two-dimensional(2D)bz(orientable Brillouin two-torus)can be fundamentally modified to a non-orientable Brillouin Klein bottle with radically distinct manifold ***,the physical consequence of artificial gauge fields on the more general three-dimensional(3D)bz(orientable Brillouin three-torus)was so far ***,we theoretically discovered and experimentally observed that the fundamental domain and topology of the usual 3D bz can be reduced to a non-orientable Brillouin Klein space or an orientable Brillouin half-turn space in a 3D acoustic crystal with artificial gauge *** experimentally identify peculiar 3D momentum-space non-symmorphic screw rotation and glide reflection symmetries in the measured band ***,we experimentally demonstrate a novel stacked weak Klein bottle insulator featuring a nonzero Z2 topological invariant and self-collimated topological surface states at two opposite surfaces related by a nonlocal twist,radically distinct from all previous 3D topological *** discovery not only fundamentally modifies the fundamental domain and topology of 3D bz,but also opens the door towards a wealth of previously overlooked momentum-space multidimensional manifold topologies and novel gaugesymmetry-enriched topological physics and robust acoustic wave manipulations beyond the existing paradigms.

关键词： Momentum-space non-symmorphic symmetry Brillouin Klein space and half-turn space Acoustic Klein bottle insulator Self-collimated topological surface states

新质生产力推动高质量发展的内在要求与原则遵循

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西南民族大学学报（人文社会科学版） 2024年第5期45卷 186-193页

作者：何毅祝建华四川师范大学马克思主义学院四川师范大学马克思主义理论研究中心四川成都610066

生产力是马克思主义政治经济学的核心范畴,是不断从低级到高级发展演进的过程。作为从传统生产力胎胞中实现新跃迁的新质生产力,其科学内涵突出体现为以科技创新为根本驱动,以新发展理念为根本遵循。新质生产力同高质量发展要求的新生... 详细信息

生产力是马克思主义政治经济学的核心范畴,是不断从低级到高级发展演进的过程。作为从传统生产力胎胞中实现新跃迁的新质生产力,其科学内涵突出体现为以科技创新为根本驱动,以新发展理念为根本遵循。新质生产力同高质量发展要求的新生产力理论指导、创新驱动经济增长方式和绿色发展鲜明底色具有高度适配性,是符合且驱动高质量发展的生产力。以新质生产力推动高质量发展过程中必须注重三个层面的原则遵循,即坚持党的领导的政治性原则、坚持因地制宜的方法论原则以及坚持以人民为中心的目的性原则。

关键词：新质生产力高质量发展科技创新原则遵循

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有机磷农药对小麦幼苗的影响研究

山东建筑工程学院学报 2000年第1期15卷 94-97页

作者：朱丽王念文崔红兰山东建筑工程学院环境工程系山东济南250014 山东建筑工程学院教务处山东济南250014 沂水城建开发公司山东沂水276400

通过模拟土壤溶液水培小麦实验 ,分别研究了有机磷农药和小麦生长量、死苗率之间的关系。在实验基础上。

关键词：有机磷农药小麦生长量死苗率