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The First Non-Chordates QRFP-Like Peptide Receptor Gene in the Cephalopod Sepiella japonica:Identification,Characterization and Possible Role in Food Intake

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Journal of Ocean University of China 2025年第1期24卷 195-208页

作者： LI Shuang HAO Qing QIU Jiayin zhou xu CHI Changfeng ZHENG Libing National and Provincial Joint Engineering Research Centre for Marine Germplasm Resources Exploration and Utilization School of Marine Science and TechnologyZhejiang Ocean UniversityZhoushan 316022China School of Food Science and Technology Jiangnan UniversityWuxi 214122China

The novel identified receptor,GPR103,now renamed QRFPR(also referred to as SP9155 or AQ27),is the endogenous receptor for the neuropeptide QRFP(also referred to as 26RFa).The distribution pattern,structure,and biological actions,such as feeding behavior,bone formation,and hormone secretion of QRFPR have been largely described in chordate species,while no research on QRFPR has been reported in non-chordate ***,the first non-chordates QRFP-like peptide receptor gene in the cephalopod Sepiella japonica(Sj_QRFPLR)was identified and *** from multiple alignments,phylogenetic analysis,and in vitro subcellular localization analysis indicated that Sj_QRFPLR is a class A GPCR and it belongs to the QRFPR ***,QRFPR is likely to be structurally conserved in cephalopod *** situ hybridization and RT-PCR data revealed a widespread distribution pattern of Sj_QRFPLR in multiple function lobes of the female brain and numerous peripheral tissues in both male and female ***,a food deprivation and refeeding experiment showed that Sj_QRFPLR is likely to stimulate food intake in ***,a possible link between Sj_QRFPLR and immune response was briefly detected in *** results will contribute to our understanding of QRFPR in the cephalopod as well as the peptidergic regulation of the QRFP/QRFPR system in non-chordates.

关键词： neuropeptide 26RFa/QRFP QRFP-like peptide receptor cuttlefish Sepiella japonica

Tunable non-Markovian and quantum coherence in the single-qubit dephasing noise channel

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Science China(Physics,Mechanics & Astronomy) 2025年第3期Mechanics & Astronomy) .卷 96-105页

作者： Na-Na Zhang Chao-Yi Wu xu zhou Qi-Yuan Liu Cheng-Ge Liu Yong-Rui Guo Ren-Pu Li School of Optoelectronic Engineering Chongqing University of Posts and Telecommunications Department of Physics Applied Optics Beijing Area Major Laboratory Beijing Normal University

In this paper, we construct a single-qubit dephasing noise channel based on the nuclear magnetic resonance（NMR） system by employing the bath-engineering technology, and achieve the construction of the tunable non-Markovian environment in the dephasing noise channel. Our findings indicate that for the single-qubit system, the transition of system dynamics from Markovian to non-Markovian can be achieved by adjusting the base frequency of the noise power spectrum. However, the base frequency corresponding to this phase transition point is not fixed, and there is a certain relationship between it and the total evolution time of the single-qubit system. Through our research, we discovered a fundamental relationship: if the single-qubit system dynamics undergoe a transition from Markovian to non-Markovian at ω0within 0-2t ms, shortening the evolution time to 0-t ms results in an increase of the phase transition point to 2ω0. This insight offers crucial guidance for artificially crafting non-Markovian environments across arbitrary time scales in single-qubit systems, and it is not limited by the type of noise. Apart from system dynamics, quantum coherence is also a focal point of our research. We find that when the system dynamics exhibit non-Markovian behavior, the quantum coherence of the single-qubit system experiences revivals. Notably, the timing of these coherence revivals aligns with the instants of the non-Markovianity enhancement. Therefore, our research also serves as a pivotal foundation for the artificial manipulation and realization of quantum coherence revivals within diverse single-qubit systems.

关键词： dephasing noise channel non-Markovian quantum coherence

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改性纳米TiO_(2)的制备及光催化降解废水性能的研究

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功能材料 2025年第1期56卷 1164-1170页

作者：吴丹刘伯赈徐洲成都理工大学工程技术学院核工程与新能源技术系四川乐山614000

以Ti(SO_(4))_(2)和Ce(NO_(3))_(3)·6H_(2)O为原料,通过水热法制备了Ce-TiO_(2)复合光催化材料,通过XRD、SEM、UV-Vis、拉曼、红外光谱、PL等手段表征了Ce-TiO_(2)复合光催化材料的晶格结构、微观形貌及光谱性能,并以罗丹明B(RhB)溶液... 详细信息

以Ti(SO_(4))_(2)和Ce(NO_(3))_(3)·6H_(2)O为原料,通过水热法制备了Ce-TiO_(2)复合光催化材料,通过XRD、SEM、UV-Vis、拉曼、红外光谱、PL等手段表征了Ce-TiO_(2)复合光催化材料的晶格结构、微观形貌及光谱性能,并以罗丹明B(RhB)溶液模拟废水,以300 W氙灯为光源进行照射,研究了Ce掺杂量对Ce-TiO_(2)光催化性能的影响。结果表明,水热法制备出的Ce-TiO_(2)复合光催化材料的晶型均属于锐钛矿相,形貌为不规则的球状颗粒。Ce的掺杂降低了Ce-TiO_(2)的禁带宽度,吸收边发生红移,光致发光测试表明TiO_(2)的本征发射峰随Ce掺杂量的增多而降低,0.9%Ce-TiO_(2)的光致发光强度最低,吸收边和禁带宽度分别为474 nm和2.62 eV,0.9%Ce-TiO_(2)在30 min时对RhB的降解率最高可达99.6%,相比纯TiO_(2)提高了82.8%,Ce-TiO_(2)对RhB的光催化降解符合一级反应动力学方程,拟合方程的相关度均超过了99%。

关键词： TiO_(2) Ce掺杂复合光催化废水降解动力学方程

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研究生教育促进新质生产力的机制研究

黑龙江高教研究 2025年第1期43卷 91-97页

作者：周均旭王涛广西大学广西南宁530004

基于2011-2020年我国30个省份的面板数据,运用双向固定效应模型、中介效应模型和门槛效应模型探究了研究生教育对新质生产力的影响效应。结果表明:在全国层面,研究生教育能够有效促进新质生产力发展,经过一系列稳健性检验结论依然成立;... 详细信息

基于2011-2020年我国30个省份的面板数据,运用双向固定效应模型、中介效应模型和门槛效应模型探究了研究生教育对新质生产力的影响效应。结果表明:在全国层面,研究生教育能够有效促进新质生产力发展,经过一系列稳健性检验结论依然成立;科技创新在研究生教育促进新质生产力发展的影响过程中发挥部分中介作用;研究生教育在促进新质生产力发展过程中存在产学研合作的门槛效应;区域异质性分析表明,研究生教育显著促进东部地区新质生产力发展,中西部地区次之,东北地区则不显著。对此,应聚焦研究生教育高质量发展,重视科技创新机制转化作用,充分发挥产学研合作调节效应,优化研究生教育布局结构,促进区域新质生产力形成与协调发展。

关键词：新质生产力研究生教育科技创新产学研合作

The miR172a–SNB module orchestrates both induced and adult-plant resistance to multiple diseases via MYB30-mediated lignin accumulation in rice

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Molecular Plant 2025年第1期18卷 59-75页

作者： He Wang Zhe-xu Wang Hong-Yuan Tian Yu-Long Zeng Hao xue Wan-Ting Mao Lu-Yue Zhang Jun-Ni Chen Xiang Lu Yong Zhu Guo-Bang Li Zhi-xue Zhao Ji-Wei Zhang Yan-Yan Huang Jing Fan Pei-zhou xu Xiao-Qiong Chen Wei-Tao Li Xian-Jun Wu Wen-Ming Wang Yan Li State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130China Rice Research Institute and Key Lab for Major Crop Diseases Sichuan Agricultural UniversityChengduChina

Plants mount induced resistance and adult-plant resistance against different pathogens throughout the whole growth *** production faces threats from multiple major diseases,including rice blast,sheath blight,and bacterial leaf ***,we report that the miR172a–SNB–MYB30 module regulates both induced and adult-plant resistance to these three major diseases via lignification in ***,pathogen infections induce the expression of miR172a,which downregulates the transcription factor SNB to release its suppression of MYB30,leading to an increase in lignin biosynthesis and disease resistance throughout the whole growth ***,expression levels of miR172a and MYB30 gradually increase and are consistently correlated with lignin contents and disease resistance during rice development,reaching a peak at full maturity,whereas SNB RNA levels are negatively correlated with lignin contents and disease resistance,indicating the involvement of the miR172a–SNB–MYB30 module in adult-plant *** functional domain of SNB protein and its binding sites in the MYB30 promoter are highly conserved among more than 4000 rice accessions,while abnormal expression of miR172a,SNB,or MYB30 compromises yield traits,suggesting artificial selection of the miR172a–SNB–MYB30 module during rice *** together,these results reveal a novel role for a conserved miRNA-regulated module that contributes significantly to induced and adult-plant resistance against multiple pathogens by increasing lignin accumulation,deepening our understanding of broad-spectrum resistance and adult-plant resistance.

关键词： miR172a SNB MYB30 lignin induced resistance adult-plant resistance

基于条件生成对抗网络与迁移学习的暂态电压稳定超前判别

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电力自动化设备 2025年第2期45卷 159-166页

作者：王渝红何其多郑宗生周旭马欢程定一赵康周辰予四川大学电气工程学院四川成都610065 国网山东省电力公司电力科学研究院山东济南250002

为解决样本不平衡导致的暂态电压稳定判别准确性不足的问题以及实现暂态电压稳定超前判别,提出一种基于条件生成对抗网络(CGAN)与迁移学习的暂态电压稳定超前判别方法。考虑暂态电压稳定样本类型,利用CGAN定向扩增暂态电压样本集,解决... 详细信息

为解决样本不平衡导致的暂态电压稳定判别准确性不足的问题以及实现暂态电压稳定超前判别,提出一种基于条件生成对抗网络(CGAN)与迁移学习的暂态电压稳定超前判别方法。考虑暂态电压稳定样本类型,利用CGAN定向扩增暂态电压样本集,解决样本不平衡问题,从而提升暂态电压稳定判别准确性;考虑到CGAN生成器与暂态电压时序预测模型具有相似的学习任务,将CGAN生成器模型迁移至暂态电压时序预测模型,结合工程判据实现暂态电压稳定超前判别,并进一步提升暂态电压稳定判别准确性。在CEPRI-VC暂态电压稳定分析系统中验证了所提方法的有效性。

关键词：暂态电压稳定稳定超前判别迁移学习条件生成对抗网络数据生成

Correction:Βρ-defined isochronous mass spectrometry at the storage ring CSRe

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Nuclear Science and Techniques 2025年第2期36卷 156-156页

作者： xu zhou Meng Wang Yu-Hu Zhang Xiao-Hong zhou Xin-Liang Yan Yuan-Ming Xing CAS Key Laboratory of High Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

Correction to:Nuclear Science and Techniques(2024)35:213 https://***/10.1007/s41365-024-01587-y The Acknowledgements section was missing from this arti-cle and should have read‘This work is supported in part by the National Key R&D Program of China(Grant No.2023YFA1606401),CAS Project for Young Scientists in Basic Research(Grant ***-002),Strategic Pri-ority Research Program of the Chinese Academy of Sci-ences(Grant ***34000000),and NSFC(Grant No.12305126).*** the support from the Young Scholar of Regional Development,CAS(Grant No.[2023]15).*** the support from the Youth Innovation Promotion Association of the Chinese Academy of Sciences(Grant No.2021419)’.

关键词： NSFC knowledge Scholar

Tandem asymmetric dearomatized functionalization reaction of phenols with Evans-ynamides enabled by divergent electrophiles

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Science China Chemistry 2025年第2期 649-660页

作者： Ying-Qi Zhang Gan-Lu Qian Yun Liu Jia-Hui Li Xin Hong zhou xu Bo zhou Long-Wu Ye State Key Laboratory of Physical Chemistry of Solid Surfaces Key Laboratory of Chemical Biology of Fujian Provinceand College of Chemistry and Chemical EngineeringXiamen University Center of Chemistry for Frontier Technologies Department of ChemistryState Key Laboratory of Clean Energy UtilizationZhejiang University Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy School of PharmacyXuzhou Medical University State Key Laboratory of Elemento-Organic Chemistry Nankai University State Key Laboratory of Organometallic Chemistry Chinese Academy of Sciences

Herein, we disclose a highly regio-/chemoselective tandem asymmetric dearomatized halofunctionalization reaction of phenoltethered ynamides with diverse electrophilic halogenation sources in a catalyst-free manner for the practical and rapid assembly of a series of halogenated spirocyclic enones. Besides, the related dearomatized selenation and protonation are also achieved,affording the corresponding selenated and protonated spirocycles in high efficiency. Moreover, the enantioselectivities of these products can be perfectly induced by Evans auxiliaries(99% ees). Significantly, this protocol not only represents the first tandem asymmetric halofunctionalization reaction of phenol derivatives, but also constitutes the first asymmetric halogenation/selenation of ynamides. Theoretical calculations indicate a remote induction model of Evans chiral auxiliary-attached keteniminium.

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富马酸二甲酯减轻帕金森病模型鼠神经损伤的作用机制

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中国组织工程研究 2025年第5期29卷 989-994页

作者：逯冉冉周旭张利杰杨新玲新疆医科大学第二附属医院新疆维吾尔自治区乌鲁木齐市830028 新疆生产建设兵团医院新疆维吾尔自治区乌鲁木齐市830000 新疆医科大学新疆维吾尔自治区乌鲁木齐市830054

背景:帕金森病是一种特征为多巴胺能神经元进行性丢失的多因素神经系统疾病,富马酸二甲酯(dimethyl fumarate,DMF)在神经退行性疾病中具有强大的神经保护和免疫调节作用。目的:探究DMF对MPTP诱导的帕金森病小鼠模型的神经保护机制。方法... 详细信息

背景:帕金森病是一种特征为多巴胺能神经元进行性丢失的多因素神经系统疾病,富马酸二甲酯(dimethyl fumarate,DMF)在神经退行性疾病中具有强大的神经保护和免疫调节作用。目的:探究DMF对MPTP诱导的帕金森病小鼠模型的神经保护机制。方法:选取24只C57BL/6系小鼠,随机将其分为对照组、模型组及DMF低剂量和DMF高剂量组。除对照组外,其余各组小鼠腹腔注射MPTP 30 mg/kg,1次/d,连续注射5 d,建立帕金森病的动物模型。每次注射MPTP后间隔30 min给予小鼠灌胃,DMF低剂量组和DMF高剂量组每天分别灌胃DMF 30,50 mg/kg,1次/d,对照组和模型组灌同等剂量的生理盐水,连续灌胃7 d。通过行为学检测、Western Blot、氧化应激标志物检测和免疫组织化学染色等方法,分析DMF对MPTP诱导的帕金森病小鼠氧化应激和Keap1/Nrf2信号通路的调节作用,以及DMF对多巴胺神经元变性的保护机制。结果与结论:①与模型组比较,DMF低剂量组小鼠的运动迟缓和姿势平衡障碍得到明显改善(P<0.01),在DMF高剂量组中的改善更为显著(P<0.01)。②与对照组相比,模型组氧化应激标志物丙二醛明显升高,超氧化物歧化酶表达降低(P<0.01);与模型组相比,DMF低、高剂量组降低了丙二醛的产生,增加了超氧化物歧化酶的表达(P<0.01)。③模型组小鼠的中脑黑质多巴胺能神经元数目和酪氨酸羟化酶蛋白表达较对照组明显减少(P<0.01),而DMF低剂量组小鼠的黑质多巴胺能神经元数目和蛋白表达增多(P<0.01),DMF高剂量组改善更明显(P<0.01)。④模型组Keap1蛋白表达升高伴随Nrf2蛋白表达降低;与模型组相比,DMF组降低了Keap1蛋白表达且伴随Nrf2蛋白表达增多(P<0.01)。⑤结果说明,DMF对帕金森病小鼠黑质区Keap1/Nrf2通路有调控作用,且与剂量呈现正相关(P<0.01),推测DMF依赖于Keap1/Nrf2信号发挥神经元保护作用。

关键词：富马酸二甲酯 DMF Keap1 Nrf2 帕金森病氧化应激神经元变性