检索结果-南通市图书馆

Current State and Challenges of Rehabilitation Needs Among Elderly-China,1990-2019

China CDC weekly 2022年第39期4卷 871-874,I0003,I0004页

作者： Xin Guo Jiakang Huo Wanwei Dai zhongyan wang Jian Du Xiaoying Zheng Erdan Dong Department of Cardiology and Institute of Vascular Medicine Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesKey Laboratory of Molecular Cardiovascular ScienceMinistry of EducationBeijing Key Laboratory of Cardiovascular Receptors ResearchResearch Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular DiseasesChinese Academy of Medical SciencesHaihe Laboratory of Cell EcosystemBeijingChina Personnel Department Peking University Third HospitalBeijingChina Office of Academic Research Peking University Third HospitalBeijingChina Research Center of Population Health and Social Development University of Health and Rehabilitation Sciences/Soft Science Research Base of Public Policy on Population Health in Shandong ProvinceQingdao CityShandong ProvinceChina National Institute of Health Data Science Peking UniversityBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina APEC Health Science Academy Peking UniversityBeijingChina Institute of Cardiovascular Sciences Peking UniversityBeijingChina

Summary What is already known about this topic?Rehabilitation is an essential part of achieving health for all,whereas the estimates of rehabilitation needs,especially for elderly individuals in China,are not clear.What is added by this report?Compared with 1990,the prevalence and years of life lived with disability for health conditions in need of rehabilitation in China increased by 71.3%and 77.0%in 2019,respectively,at a rate much higher than the global average.What are the implications for public health practices?This study mainly presents scientific data and a systematic analysis of the current state and challenges of rehabilitation needs for elderly individuals(aged 60 and above)in China based on the World Health Organization Rehabilitation Need Estimator.

关键词： rehabilitation Rehabilitation elderly

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparative pharmacokinetics of six components in normal and rheumatoid arthritis rats after intragastrical administration of Qianghuo Shengshi Decoction granules by LC-MS/MS

引用

Chinese Herbal Medicines 2024年第3期16卷 457-465页

作者： Xin Li Min wang Yuhong Zhong Qianqian Yin Zheming Hu Wenli Tian zhongyan Liu Zhidong Liu Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique Ministry of EducationTianjin University of Traditional Chinese Medicine State Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese Medicine

Objective:To investigate the plasma pharmacokinetics of six representative components(nodakenin,osthole,5-0-methylvisammioside,ferulic acid,liquiritigenin,and liquiritin),which were the ingredients of Qianghuo Shengshi Decoction(QSD) granules,in normal and rheumatoid arthritis(RA) rats administrated QSD granules intragastrically.Methods:A rapid and accurate ultra-high performance liquid chromatography-tandem mass spectrometry(LC-MS/MS) method was developed for the simultaneous determination of six components in plasma,and it showed a good specificity,linearity,intra-day and inter-day precision,intra-day and inter-day accuracy,extraction recovery,stability,and the less matrix effect.Results:The validated LC-MS/MS method was successfully used to compare the plasma pharmacokinetics of six ingredients between normal and RA rats after intragastrical administration of QSD granules and differences in the pharmacokinetics were found in two types of rats.The absorption rate in the RA rats was lower for nodakenin,osthole,5-0-methylvisammioside,liquiritigenin and liquiritin than in the normal group,while the absorption rate of ferulic acid remained constant in two groups.In comparison with the normal rats,the exposure concentration of nodakenin was higher and that of other five components except for nodakenin was lower under pathological conditions.Additionally,the absorptive amount of nodakenin,osthole,5-0-methylvisammioside and liquiritin was increased and that of ferulic acid and liquiritigenin was reduced in the RA rats than in the normal rats.Compared with the normal rats,the retention time of nodakenin,ferulic acid and liquiritin was reduced in vivo,whereas the retention time of osthole,5-0-methylvisammioside and liquiritigenin was raised in the body for the RA rats.In contrast to the normal rats,the data demonstrated an increase in the elimination velocity of nodakenin and a decrease in the elimination velocity of the other five components except for nodakenin in the pathological state.Conclusion:This study showed th

关键词： LC-MS/MS pharmacokinetics Qianghuo Shengshi Decoction granules rheumatoid arthritis

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The role of CO_(2)dissociation in CO_(2)hydrogenation to ethanol on CoCu/silica catalysts

引用

Nano Research 2023年第5期16卷 6128-6133页

作者： zhongyan wang Chengsheng Yang Xianghong Li Xiwen Song Chunlei Pei Zhi-Jian Zhao Jinlong Gong Key Laboratory for Green Chemical Technology of Ministry of Education School of Chemical Engineering and TechnologyCollaborative Innovation Center of Chemical Science and EngineeringTianjin UniversityTianjin 300072China Joint School of National University of Singapore and Tianjin University International Campus of Tianjin UniversityFuzhou 350207China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

CoCu-based catalysts are widely used in CO_(x) hydrogenation reactions to produce higher alcohols due to the C–C coupling ability of Co and the ability of Cu to produce alcohols.This work describes the role of easily happened CO_(2)dissociation on the CoCu surface during the reaction,using different silica support to tune the metal–support interaction,reaches different selectivity to ethanol.CoCu supported on mesoporous silica MCM-41 shows ethanol selectivity as high as 85.3%,the ethanol space-time yield(STY)is 0.229 mmol/(gmetal∙h),however,poor selectivity to ethanol as low as 28.8%is observed on CoCu supported on amorphous silica.The different selectivity is due to the different intensities of CO_(2)dissociation on the catalysts.The adsorbed O*produced via CO_(2)dissociation can occupy the cobalt hollow sites on CoCu surfaces,which are also the adsorption sites of C1 intermediates for further C–C coupling.

关键词： CO_(2)hydrogenation bimetallic catalysts cobalt catalysts CO_(2)dissociation ethanol synthesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of Cold Spells on Ischemic Stroke Severity and Clinical Outcomes in Tianjin, China

引用

Journal of Meteorological Research 2023年第4期37卷 564-572页

作者： Juanjuan XUE Chanjuan WEI Xiaoshuang XIA Xuemei QI Yumeng GU zhongyan wang Suqin HAN Lin wang Xin LI Department of Neurology The Second Hospital of Tianjin Medical UniversityTianjin 300200 Department of Geriatrics The Second Hospital of Tianjin Medical UniversityTianjin 300200 Tianjin Environmental Meteorology Center Tianjin 300200

There are several studies on the impact of extreme weather on the incidence and mortality of stroke, but the research on the effect of extreme weather events on severity and outcome of ischemic stroke is scarce. This study aimed to evaluate the impact of cold spells on the severity and clinical outcomes of patients with initial acute ischemic stroke in a hospital-based study. We enrolled 553 patients with initial ischemic stroke during the cold seasons between 2016 and 2019. Patients were separated into the mild stroke group and moderate-to-severe stroke group according to the National Institutes of Health Stroke Scale(NIHSS) of the U.S., and good outcome group and poor outcome group according to modified Rankin Scale(mRS) scores. There are nine different definitions of cold spells according to intensities and duration time. After adjustment for climate factors, air quality index, and common risk factors, it is found that cold spells were associated with moderate-to-severe neurological deficits and clinical outcomes in overall ischemic stroke patients. Furthermore, the delay effect for stroke severity started at the beginning of the cold wave(Lag 0) and lasted up to 14 days(Lags 0–14). In addition, when a cold spell was set as a daily mean temperature < 3rd or 5th percentile and with a duration ≥ 2 or 3 consecutive days, cold spells had a significant impact on clinical outcomes, and there was a definite delay effect of at least 7 days(Lags 0–7) and it lasted up to 14days(Lags 0–14). At last, we concluded that cold spells may be a contributory factor for more severe neurological deficits and worse outcomes in patients with initial ischemic stroke.

关键词： cold spell meteorological data ischemic stroke severity treatment outcome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inkjet printing-based fabrication of microscale 3D ice structures

引用

Microsystems & Nanoengineering 2020年第1期6卷 305-314页

作者： Fengyi Zheng zhongyan wang Jiasheng Huang Zhihong Li National Key Laboratory of Science and Technology on Micro/Nano Fabrication Institute of MicroelectronicsPeking UniversityBeijing 100871China

This study proposed a method for fabricating 3D microstructures of ice without a supporting material.The inkjet printing process was performed in a low humidity environment to precisely control the growth direction of the ice crystals.In the printing process,water droplets(volume=hundreds of picoliters)were deposited onto the previously formed ice structure,after which they immediately froze.Different 3D structures(maximum height=2000µm)could be formed by controlling the substrate temperature,ejection frequency and droplet size.The growth direction was dependent on the landing point of the droplet on the previously formed ice structure;thus,3D structures could be created with high degrees of freedom.

关键词： printing structures hundreds

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High‑Performance Flexible Microneedle Array as a Low‑Impedance Surface Biopotential Dry Electrode for Wearable Electrophysiological Recording and Polysomnography

引用

Nano-Micro Letters 2022年第8期14卷 142-163页

作者： Junshi Li Yundong Ma Dong Huang zhongyan wang Zhitong Zhang Yingjie Ren Mengyue Hong Yufeng Chen Tingyu Li Xiaoyi Shi Lu Cao Jiayan Zhang Bingli Jiao Junhua Liu Hongqiang Sun Zhihong Li National Key Laboratory of Science and Technology on Micro/Nano Fabrication School of Integrated CircuitsPeking UniversityBeijing 100871People’s Republic of China Peking University Sixth Hospital Peking University Institute of Mental HealthNHC Key Laboratory of Mental Health(Peking University)National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital)Beijing 100191People’s Republic of China School of Electronics Peking UniversityBeijing 100871People’s Republic of China Hypnometry Microsystem Beijing 100871People’s Republic of China College of Engineering Peking UniversityBeijing 100871People’s Republic of China

Microneedle array(MNA)electrodes are an effective solution to achieve high-quality surface biopotential recording without the coordination of conductive gel and are thus very suitable for long-term wearable applications.Existing schemes are limited by flexibility,biosafety,and manufacturing costs,which create large barriers for wider applications.Here,we present a novel flexible MNA electrode that can simultaneously achieve flexibility of the substrate to fit a curved body surface,robustness of microneedles to penetrate the skin without fracture,and a simplified process to allow mass production.The compatibility with wearable wireless systems and the short preparation time of the electrodes significantly improves the comfort and convenience of electrophysiological recording.The normalized electrode–skin contact impedance reaches 0.98 kΩcm^(2)at 1 kHz and 1.50 kΩcm^(2)at 10 Hz,a record low value compared to previous reports and approximately 1/250 of the standard electrodes.The morphology,biosafety,and electrical/mechanical properties are fully characterized,and wearable recordings with a high signal-to-noise ratio and low motion artifacts are realized.The first reported clinical study of microneedle electrodes for surface electrophysiological monitoring was conducted in tens of healthy and sleep-disordered subjects with 44 nights of recording(over 8 h per night),providing substantial evidence that the electrodes can be leveraged to substitute for clinical standard electrodes.

关键词： Flexible microneedle array Dry electrode Low-impedance electrode–skin contact Wearable wireless electrophysiological recording Polysomnography

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

电磁导航床旁鼻肠管置管技术在老年卧床患者中的应用

引用

中华护理杂志 2024年第1期59卷 70-76页

作者：马骁石海燕王湘王军韩中彦张华果解放军总医院第二医学中心/国家老年疾病临床医学研究中心消化内科北京市100853 首都医科大学附属北京世纪坛医院护理部

目的探讨电磁导航床旁鼻肠管置管技术在老年卧床患者中的应用效果。方法采用便利抽样法,选取2021年6月—2022年12月北京市某三级甲等医院收治的92例老年卧床管饲患者作为应用对象,采用随机数字表法将其分为试验组和对照组各46例。试验... 详细信息

目的探讨电磁导航床旁鼻肠管置管技术在老年卧床患者中的应用效果。方法采用便利抽样法,选取2021年6月—2022年12月北京市某三级甲等医院收治的92例老年卧床管饲患者作为应用对象,采用随机数字表法将其分为试验组和对照组各46例。试验组采用电磁导航床旁鼻肠管置管技术留置鼻肠管,对照组采用盲插法留置鼻肠管,比较两组的总置管成功率、一次置管成功率、置管用时、导管尖端到达空肠的比例、置管相关并发症发生率。结果两组均无脱落病例。试验组总置管成功率为95.7%,对照组为80.4%;试验组一次置管成功率为95.7%,对照组为71.7%;试验组置管用时为(12.37±4.19)min,对照组为(19.22±5.48)min;试验组导管尖端到达空肠的比例为60.9%,对照组为28.3%。以上数据两组比较,差异均具有统计学意义(P0.05);两组均未发生导管异位、气胸、穿孔等并发症。结论采用电磁导航床旁鼻肠管置管技术为老年卧床患者留置鼻肠管的成功率高,用时短,可提升导管尖端到达空肠的比例,降低鼻出血、便潜血试验阳性发生率。

关键词：电磁导航鼻肠管肠内营养老年人卧床患者护理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于复合标志的四旋翼无人机自主降落系统

引用

传感器与微系统 2024年第3期43卷 103-107页

作者：袁泽慧陈国栋张亚王忠言中北大学机电工程学院山西太原030051 江苏省机器人技术及智能制造装备工程实验室(苏州大学) 江苏苏州215021

四旋翼无人机能否快速、精确地降落在地面充电装置或回收装置上是实现空地机器人协同的关键步骤之一。提出了一种基于视觉的四旋翼无人机在静止平台上自主降落的模型化框架,设计了基于AprilTag的复合标签着陆标志,将视觉测量与无人机自... 详细信息

四旋翼无人机能否快速、精确地降落在地面充电装置或回收装置上是实现空地机器人协同的关键步骤之一。提出了一种基于视觉的四旋翼无人机在静止平台上自主降落的模型化框架,设计了基于AprilTag的复合标签着陆标志,将视觉测量与无人机自驾仪提供的状态信息利用卡尔曼滤波器进行融合,提高无人机位姿估计精度。利用PID控制器计算无人机的期望加速度,并将其转化为无人机的姿态指令,使得无人机飞行到期望位置。在专用模拟器下,对提出的无人机自主降落系统进行了多次仿真,仿真结果表明,无人机的平均降落误差小于5cm,验证了无人机自主降落系统的有效性和精确性。

关键词：四旋翼无人机自主降落低成本单目摄像头卡尔曼滤波器

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

洋中脊弯折带的构造-岩浆耦合作用:西北印度洋中脊火山锥及断层分布的约束

引用

岩石学报 2024年第7期40卷 2215-2224页

作者：党牛余星韩喜球吴招才邱中炎王叶剑李洪林自然资源部海底科学重点实验室自然资源部第二海洋研究所杭州310012 福建师范大学地理科学学院福州350007 浙江大学海洋学院舟山316021

洋中脊作为全球火山活动最活跃的区域之一,岩浆以裂隙式喷发为主,同时也存在中心式喷发火山锥。本文基于西北印度洋中脊大洋24航次的船载多波束地形数据,选择具有特殊空间位置和构造属性的北部弯折带作为研究靶区,应用定量地貌学方法分... 详细信息

洋中脊作为全球火山活动最活跃的区域之一,岩浆以裂隙式喷发为主,同时也存在中心式喷发火山锥。本文基于西北印度洋中脊大洋24航次的船载多波束地形数据,选择具有特殊空间位置和构造属性的北部弯折带作为研究靶区,应用定量地貌学方法分析火山锥形态特征与空间分布,探索区域火山作用与构造活动的耦合关系。结果表明,火山锥沿洋脊纵向上的分布主要受控于岩浆供应量,但段内其横向上的分布不仅与岩浆供应量有关,还决定于火山锥岩浆通道的形成。火山锥的分布与断层分布密切相关,断层分布密集,易于火山锥通道的形成。弯折带的洋脊段除了受扩张力外,还受到北东方向的应力作用,使弯折带南翼发育有更密集的断层,更高的火山锥密度。该应力效应的产生与非洲板块的北东向推移、印度板块的逆时针旋转以及弯折带效应本身有关。火山锥形态特征与空间分布,对于理解洋中脊区域构造演化以及火山活动过程具有重要价值。

关键词：火山锥分布特征构造-岩浆背景定量地貌学西北印度洋中脊

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

党的二十大精神融入高校思政课教学的价值意蕴、基本原则与推进策略

引用

无锡职业技术学院学报 2024年第2期23卷 88-92页

作者：王桂林徐忠艳重庆邮电大学马克思主义学院重庆南岸400065

党的二十大精神融入高校思政课教学,对推动党和国家事业发展、促进新时代大学生健康成长、推进高校思政课创新发展具有深远意义。将党的二十大精神融入高校思政课教学应遵循政治性和学理性相统一、全面性和重点性相结合、理论教学和实... 详细信息

党的二十大精神融入高校思政课教学,对推动党和国家事业发展、促进新时代大学生健康成长、推进高校思政课创新发展具有深远意义。将党的二十大精神融入高校思政课教学应遵循政治性和学理性相统一、全面性和重点性相结合、理论教学和实践教学相结合的基本原则,在融入过程中要抓好教师这一关键力量,强化科学技术赋能,开展多元实践活动,确保党的二十大精神全面系统进课堂、进学生头脑。

关键词：党的二十大精神高校思政课教学推进策略

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：