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Study on Intervention of Blood Sugar and Blood Lipid in Diabetic Mice by Abrus Cantoniensis and Armeniaca mume Sieb and Their Compatibility

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TMR Pharmacology Research 2021年第4期1卷 13-19页

作者： Yixin Zhang Shibo Zhao Sitong Lu Danni Lu Yedong Shen Changhuan He zhonggang wu Suoyi Huang College of Clinical Medicine Youjiang Medical University for NationalitiesBaiseChina Key Laboratory of Guangxi Universities on National Medicine in Youjiang River BaiseChina

Objective:The study aims to explore the interventional effect of Abrus cantonensis and Armeniaca mume Sieb and their compatibility on blood glucose and blood lipid in diabetic mice and to explore the optimal ratio of efficacy of their ***:SPF Kunming male mice were fed with high sugar and high fat diet for 6 weeks and then intraperitoneally injected with STZ solution to establish a diabetes *** successfully modeled mice were randomly divided into 6 groups according to their body weight:model group,Abrus Cantoniensis group,Armeniaca mume Sieb group,as well as Abrus Cantoniensis and Armeniaca mume Sieb group divided into 1:2,1:1 and 2:1 groups according to volume ratio with 10 mice in each *** 10 healthy mice were taken as blank group and intraperitoneally injected with sodium citrate *** corresponding solution was given intragastric administration by body mass once a day for 20 *** the last administration,fasting was performed for 12 *** was collected by the method of eyeball blood collection to determine the contents of fasting blood glucose,total cholesterol Triacylglycerol,triglyceride,low density lipoprotein and high-density ***:Compared with Abrus Cantoniensis and Armeniaca mume Sieb groups,Glu,TG,TC and LDL-C of the three compatibility groups significantly decreased,with the most significant decrease in the compatibility group 1:2,while there was no significant difference in HDL-C among all ***:Abrus Cantoniensis and Armeniaca mume Sieb and their combination have synergistic effects on the improvement of blood glucose and lipid levels in mice with high glucose and high fat combined with STZ-induced diabetes mellitus *** all the experimental groups,the compatibility 1:2 group had the best effect.

关键词： Abrus Cantoniensis Armeniaca mume Sieb compatibility diabetes mellitus blood sugar blood lipid

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一种基于局部相似性的社区发现算法

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计算机工程 2016年第12期42卷 196-203页

作者：吴钟刚吕钊华东师范大学计算机科学技术系上海200241

现有社区发现算法大多仅考虑图的拓扑结构或节点的属性信息,其中结合两者的属性图聚类算法挖掘效果不理想,而基于共享邻居的局部相似性算法却未充分度量节点间相似度。针对上述问题,提出一种新的基于局部相似性的节点相似度社区发现算... 详细信息

现有社区发现算法大多仅考虑图的拓扑结构或节点的属性信息,其中结合两者的属性图聚类算法挖掘效果不理想,而基于共享邻居的局部相似性算法却未充分度量节点间相似度。针对上述问题,提出一种新的基于局部相似性的节点相似度社区发现算法。该算法包括基于局部相似性的节点相似度计算和节点聚类2个模块。利用Pagerank算法计算基于图链接结构的节点重要性,衡量节点间的链接强度并结合节点的属性得到节点对相似性。为避免基于共享邻居的节点相似度计算的低估倾向,引入邻居节点集之间的相似度作为节点局部相似性。采用K-Medoids聚类算法将节点与分组中心节点的局部相似性值作为节点类别归属的判断,得到社区划分的结果。实验结果表明,与经典SA-Cluster与k-SNAP等算法相比,该算法能挖掘出质量更高的社区,具有较好的社区划分效果。

关键词：社区发现图聚类属性图节点重要性局部相似性节点相似度

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普列克底物蛋白同源结构域家族A成员1蛋白在肿瘤中的研究进展

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中国医学科学院学报 2022年第5期44卷 863-867页

作者：赵士博马汉俊吴忠港凌博叶广彬右江民族医学院临床医学院广西百色533000 右江民族医学院药学院广西百色533000 右江民族医学院基础医学院广西百色533000

普列克底物蛋白同源结构域家族A成员1蛋白(PHLDA1)又称TDAG51,其异常表达与肿瘤的发生、发展和转移密切相关。本文对PHLDA1的基因结构、生物学特性及其在乳腺癌、胃癌、肝癌、黑色素瘤和骨肉瘤等多种恶性肿瘤中的研究进展进行综述,以期... 详细信息

普列克底物蛋白同源结构域家族A成员1蛋白(PHLDA1)又称TDAG51,其异常表达与肿瘤的发生、发展和转移密切相关。本文对PHLDA1的基因结构、生物学特性及其在乳腺癌、胃癌、肝癌、黑色素瘤和骨肉瘤等多种恶性肿瘤中的研究进展进行综述,以期更全面综合地了解PHLDA1基因及其对肿瘤诊断治疗的临床意义。

关键词：普列克底物蛋白同源结构域家族A成员1蛋白生物特性肿瘤研究进展

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Tectonic modes of mantle convection and their implications for Earth's tectonic evolution based on three-dimensional numerical simulations

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Science China Earth Sciences 2025年第1期68卷 270-296页

作者： Song XIANG Jinshui HUANG Bingcheng wu School of Earth and Space Sciences University of Science and Technology of China CAS Center of Excellence in Comparative Planetary Studies

Five tectonic modes of mantle convection are obtained and analyzed with three-dimensional numerical models in a spherical shell domain. The five tectonic convective modes are non-plate mobile-lid, plate-like mobile-lid, episodic plate-like mobile-lid, episodic stagnant-lid, and stagnant-lid convective modes, respectively. The typical characteristics of these five tectonic modes and their numerical classification criteria based on plateness, mobility, and their standard deviations are presented and discussed. The results show that the yield stress of the lithosphere has profound effects on the tectonic convective *** the gradual increase of yield stress, the tectonic mode of mantle convection changes from one to another sequentially through the aforementioned five modes. Additionally, as the Rayleigh number increases, the range of yield stress for the platelike mobile-lid convective mode decreases, and the dimensionless transition stress between different tectonic modes ***, the dimensional transition stress between the non-plate mobile-lid convective mode and plate-like mobile-lid convective mode increases with the increase of Rayleigh number, but decreases between other tectonic modes. Furthermore, we find that the transition stress between different tectonic modes is inversely proportional to the internal heating rate, with the transition stress decreasing as the internal heating rate increases. The fitting analysis of the transition stress between tectonic modes shows that Earth's current plate tectonics correspond to a lithospheric yield stress of 150–250 MPa, which aligns with the strength of serpentinized mantle rock determined by experimental petrography. If the Archean mantle was 300°C warmer than it is today, then the Earth was in an episodic stagnant-lid convective mode. The tectonic evolution of the Earth's surface is closely related to the lithospheric strength and the process of thermal evolution. If the lithospheric strength w

关键词： Tectonic mode of mantle convection Plate-like mobile-lid convection Episodic plate-like mobile-lid convection Episodic stagnant-lid convection Plate tectonics and tectonic evolution of the Earth

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Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第2期20卷 483-484页

作者： Yun Li Junfang wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

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Crustal magma oxidation state and endowments in porphyry copper deposits

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Science China Earth Sciences 2025年第1期68卷 226-236页

作者： Yumin AI Massimo CHIARADIA Chao wu Huayong CHEN Key Laboratory of Mineralogy and Metallogeny Guangzhou Institute of Geochemistry Chinese Academy of Sciences University of Chinese Academy of Sciences Department of Earth Sciences University of Geneva Guangdong Provincial Key Laboratory of Mineral Physics and Materials

Porphyry copper deposits（PCDs） supply the majority of the world's copper（Cu） as well as significant amounts of molybdenum（Mo） and gold（Au）. The formation of these deposits is controlled by a variety of geological factors, among which the magmatic oxidation is one of the focuses of current research. This study investigates the redox characteristics of arc magmas by analyzing the ratio of vanadium（V） to scandium（Sc） and its correlation with the oxygen fugacity （fO2） of magmas from arcs of various crustal thicknesses globally. We compiled an extensive dataset of published V/Sc values and studied the partition coefficients of Vand Sc between minerals and silicate melts across various magmatic environments. The results demonstrate that fractional crystallization of magnetite markedly reduces V/Sc values of the residual melt. Furthermore, magnesium number（Mg#） at the onset of magnetite fractionation is strongly positively correlated with fO2of the equilibrium magma. Based on this,the oxidation of arc magmas from different crustal thicknesses can be evaluated. The result suggests that magmas generated in crusts thicker than 20 km tend to be more oxidized with increasing crust thickness. This trend is attributed to enhanced intracrustal differentiation processes involving garnet and amphibole, particularly in mature island and continental arcs. In contrast,magmas in thinner arc crusts（<20 km）, which are significantly influenced by subducted slab materials, display higher oxidation states than most of their thicker crust counterparts. These findings suggest that both subduction dynamics and crustal thickness play a vital role in determining the oxidation state of arc magmas and, consequently, their capacity to generate PCDs. Highly oxidized, primitive arc magmas are less favorable for PCD formation due to that they tend to experience magnetite fractionation and thus sulfide saturation in the early stage of magma evolution, a process leading to copper depletion. On the contra

关键词： Magma evolution V/Sc systematics Magnetite Oxygen fugacity Porphyry copper deposits

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室内卷烟阴燃颗粒物的粒径分布与迁移特性

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燃烧科学与技术 2014年第4期20卷 368-372页

作者：胡玉琦周晓冬章涛林吴众刚陈艳秋杨立中中国科学技术大学火灾科学国家重点实验室合肥230026

为探究卷烟阴燃亚微米颗粒物在室内环境中的粒径分布与迁移特性,采用DMS500快速型微粒光谱仪在线监测室内不同位置处卷烟阴燃粒径在5-1,000,nm范围内的烟颗粒,记录并分析随时间变化的气溶胶粒径谱分布信息,得到以累计颗粒数密度、几何... 详细信息

为探究卷烟阴燃亚微米颗粒物在室内环境中的粒径分布与迁移特性,采用DMS500快速型微粒光谱仪在线监测室内不同位置处卷烟阴燃粒径在5-1,000,nm范围内的烟颗粒,记录并分析随时间变化的气溶胶粒径谱分布信息,得到以累计颗粒数密度、几何中位径、颗粒数目衰减指数为表征的室内亚微米颗粒物迁移特性参数.结果表明：卷烟阴燃前后亚微米烟颗粒粒径谱呈现不同的对数偏态分布,且室内不同位置烟颗粒粒径谱形态类似;扩散、沉降、凝并等作用是导致烟颗粒在一定范围内迁移呈现不同变化规律的影响因素.

关键词：烟颗粒室内环境粒径分布迁移特性

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“双一流”建设背景下翻转课堂在医用化学教学改革中的应用探索与研究

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山东化工 2019年第22期48卷 244-246页

作者：赵士博吴忠港郑淮远黄锁义右江民族医学院临床医学院广西百色533000 右江民族医学院药学院科学实验中心广西百色533000 右江民族医学院广西高校右江流域特色民族药研究重点实验室广西百色533000

目的:“双一流”建设背景下高等教育教学改革势在必行,现以医用化学教学改革为例,对翻转课堂在高校医学专业教育教学改革中的应用进行研究。方法:通过与其他教学模式在医用化学教学中的应用进行对比分析,对翻转课堂在医用化学教学改革... 详细信息

目的:“双一流”建设背景下高等教育教学改革势在必行,现以医用化学教学改革为例,对翻转课堂在高校医学专业教育教学改革中的应用进行研究。方法:通过与其他教学模式在医用化学教学中的应用进行对比分析,对翻转课堂在医用化学教学改革中的应用进行研究与探索。结果:借鉴翻转课堂在其他学科教学中的应用,对医用化学的教学理念与人才培养模式进行调整与完善,打造成具有医用化学教学特色的翻转课堂教学模式。结论:翻转课堂教学模式在医用化学教学中的应用理论上能够推动医用化学的学科发展与进步。有助于强化医学生的理论基础与操作水平,是提升医学生专业水平与综合能力的有效手段。

关键词：双一流翻转课堂医用化学教学改革理论研究能力培养

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A Verifiable Trust-Based CP-ABE Access Control Scheme for Cloud-Assisted Renewable Energy Systems

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Computers, Materials & Continua 2025年第1期82卷 1211-1232页

作者： Jiyu Zhang Kehe wu Ruomeng Yan Zheng Tian Yizhen Sun Yuxi wu Yaogong Guo Department of Control and Computer Engineering North China Electric Power UniversityBeijing102206China State Grid Information&Communication Company of Hunan Electric Power Corporation Changsha410118China State Grid Hunan Electric Power Corporation Chenzhou Power Supply Branch Chenzhou423000China

Renewable Energy Systems(RES)provide a sustainable solution to climate warming and environmental pollution by enhancing stability and reliability through status acquisition and analysis on cloud platforms and intelligent processing on edge servers(ES).However,securely distributing encrypted data stored in the cloud to terminals that meet decryption requirements has become a prominent research ***,managing attributes,including addition,deletion,and modification,is a crucial issue in the access control scheme for *** address these security concerns,a trust-based ciphertext-policy attribute-based encryption(CP-ABE)device access control scheme is proposed for RES(TB-CP-ABE).This scheme effectivelymanages the distribution and control of encrypted data on the cloud through robust attribute key *** introducing trust management mechanisms and outsourced decryption technology,the ES system can effectively assess and manage the trust worthiness of terminal devices,ensuring that only trusted devices can participate in data exchange and access sensitive ***,the ES system dynamically evaluates trust scores to set decryption trust thresholds,thereby regulating device data access permissions and enhancing the system’s *** validate the security of the proposed TB-CP-ABE against chosen plaintext attacks,a comprehensive formal security analysis is conducted using the widely accepted random oraclemodel under the decisional q-Bilinear Diffie-Hellman Exponent(q-BDHE)***,comparative analysis with other schemes demonstrates that the TB-CP-ABE scheme cuts energy/communication costs by 43%,and scaleswell with rising terminals,maintaining average latency below 50ms,ensuring real-time service *** proposed scheme not only provides newinsights for the secure management of RES but also lays a foundation for future secure energy solutions.

关键词： Access control renewable energy systems(RES) ciphertext-policy attribute-based encryption(CP-ABE) security

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Hourglass-GCN for 3D Human Pose Estimation Using Skeleton Structure and View Correlation

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Computers, Materials & Continua 2025年第1期82卷 173-191页

作者： Ange Chen Chengdong wu Chuanjiang Leng Faculty of Robot Science and Engineering Northeastern UniversityShenyang110169China

Previous multi-view 3D human pose estimation methods neither correlate different human joints in each view nor model learnable correlations between the same joints in different views explicitly,meaning that skeleton structure information is not utilized and multi-view pose information is not completely ***,existing graph convolutional operations do not consider the specificity of different joints and different views of pose information when processing skeleton graphs,making the correlation weights between nodes in the graph and their neighborhood nodes *** Graph Convolutional Networks(GCNs)cannot extract global and deeplevel skeleton structure information and view correlations *** solve these problems,pre-estimated multiview 2D poses are designed as a multi-view skeleton graph to fuse skeleton priors and view correlations explicitly to process occlusion problem,with the skeleton-edge and symmetry-edge representing the structure correlations between adjacent joints in each viewof skeleton graph and the view-edge representing the view correlations between the same joints in different *** make graph convolution operation mine elaborate and sufficient skeleton structure information and view correlations,different correlation weights are assigned to different categories of neighborhood nodes and further assigned to each node in the *** on the graph convolution operation proposed above,a Residual Graph Convolution(RGC)module is designed as the basic module to be combined with the simplified Hourglass architecture to construct the Hourglass-GCN as our 3D pose estimation ***-GCNwith a symmetrical and concise architecture processes three scales ofmulti-viewskeleton graphs to extract local-to-global scale and shallow-to-deep level skeleton features *** results on common large 3D pose dataset Human3.6M and MPI-INF-3DHP show that Hourglass-GCN outperforms some excellent methods in 3D pose estimati

关键词： 3D human pose estimation multi-view skeleton graph elaborate graph convolution operation Hourglass-GCN

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