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SEI/dead Li-turning capacity loss for high-performance anode-free solid-state lithium batteries

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Journal of Energy Chemistry 2024年第9期96卷 145-152页

作者： Qianwen yin Tianyu Li Hongzhang zhang Guiming zhong Xiaofei Yang Xianfeng Li Division of Energy Storage Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Long-Duration and Large-Scale Energy Storage Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina Laboratory of Advanced Spectro-Electrochemistry and Lithium-Ion Batteries Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina

Anode-free solid-state lithium metal batteries(AF-SSLBs)have the potential to deliver higher energy density and improved safety beyond lithium-metal ***,the unclear mechanism for the fast capacity decay in AF-SSLBs,either determined by dead Li or solid electrolyte interface(SEI),limits the proposal of effective strategies to prolong cycling *** clarify the underlying mechanism,herein,the evolution of SEI and dead Li is quantitatively analyzed by a solid-state nuclear magnetic resonance(ss-NMR)technology in a typical LiPF6-based polymer *** results show that the initial capacity loss is attributed to the formation of SEI,while the dead Li dominates the following capacity loss and the growth rate is 0.141 mA h cm^(−2)cycle−*** reduce the active Li loss,the combination of inorganic-rich SEI and self-healing electrostatic shield effect is proposed to improve the reversibility of Li deposition/dissolution behavior,which reduces the capacity loss rate for the initial SEI and following dead Li generation by 2.3 and 20.1 folds,*** a result,the initial Coulombic efficiency(ICE)and stable CE increase by 15.1%and 15.3%in Li-Cu cells,which guides the rational design of high-performance AF-SSLBs.

关键词： Solid-state lithium batteries Solid-state NMR Anode-free SEI Dead Li

Strain sensor on a chip for quantifying the magnitudes of tensile stress on cells

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Microsystems & Nanoengineering 2024年第3期10卷 305-315页

作者： Yuyin zhang Yue Wang Hongze yin Jiahao Wang Na Liu Songyi zhong Long Li Quan zhang Tao Yue School of Mechatronics Engineering and Automation Shanghai UniversityShanghaiChina School of Future Technology Shanghai UniversityShanghaiChina Key Laboratory of Advanced Manufacturing Technology of Zhejiang Province School of Mechanical EngineeringZhejiang UniversityHangzhouChina Shanghai Key Laboratory of Intelligent Manufacturing and Robotics Shanghai UniversityShanghaiChina Shanghai Institute of Intelligent Science and Technology Tongji UniversityShanghaiChina

During cardiac development,mechanotransduction from the in vivo microenvironment modulates cardiomyocyte growth in terms of the number,area,and arrangement ***,the response of cells to different degrees of mechanical stimuli is ***-on-a-chip,as a platform for investigating mechanical stress stimuli in cellular mimicry of the in vivo microenvironment,is limited by the lack of ability to accurately quantify externally induced ***,previous technology lacks the integration of external stimuli and feedback sensors in microfluidic platforms to obtain and apply precise amounts of external ***,we designed a cell stretching platform with an in-situ *** in-situ liquid metal sensors can accurately measure the mechanical stimulation caused by the deformation of the vacuum cavity exerted on *** platform was applied to human cardiomyocytes(AC16)under cyclic strain(5%,10%,15%,20 and 25%),and we found that cyclic strain promoted cell growth induced the arrangement of cells on the membrane to gradually unify,and stabilized the cells at 15%amplitude,which was even more effective after 3 days of *** platform’s precise control and measurement of mechanical forces can be used to establish more accurate in vitro microenvironmental models for disease modeling and therapeutic research.

关键词： stress deformation arrangement

Diagnosis of cytomegalovirus encephalitis using metagenomic nextgeneration sequencing of blood and cerebrospinal fluid:A case report

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World Journal of Clinical Cases 2022年第14期10卷 4601-4607页

作者： Chang-Qing Xu Xia-Ling Chen Dong-Sheng zhang Jia-Wei Wang Hong Yuan Wei-Fan Chen Han Xia zhong-yin zhang Fu-Hua Peng Department of Neurology Dongguan Kanghua HospitalDongguan 523080Guangdong ProvinceChina Department of Scientific Affairs Hugobiotech Co.Ltd.Beijing 100176China Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Cytomegalovirus(CMV)infections in the population are mostly subclinical,inapparent,or ***,it is rare in brain *** reported CMV encephalitis cases were patients with *** diagnosis and detection rate of CMV encephalitis in patients with normal immune function needs to be further *** SUMMARY An 86-year-old male was admitted due to a sudden onset of unconsciousness for 3 *** patient developed status epilepticus and was relieved after antiepileptic *** was considered due to the high signals of diffusionweighted imaging sequences in the right central region by magnetic resonance *** next-generation sequencing(mNGS)of blood and cerebrospinal fluid revealed CMV,with unique reads number being 614 and 1,*** quantitative PCR results showed CMV positive in blood samples and negative in cerebrospinal fluid *** patient was finally diagnosed as CMV encephalitis with status *** the antiviral,hormonal,andγ-globulin pulse therapy,the patient’s condition improved,and he was finally *** mNGS could be a reliable approach for the diagnosis of CMV encephalitis,with high efficiency,sensitivity,and specificity.

关键词： Cytomegalovirus encephalitis Metagenomic next-generation sequencing Quantitative real-time PCR Diagnosis Case report

Mechanical Janus lattice with plug-switch orientation

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Theoretical & Applied Mechanics Letters 2024年第1期14卷 23-26页

作者： Yupei zhang Jiawei zhong Zhengcai Zhao Ruiyu Bai Yanqi yin Yang Yu Bo Li State Key Laboratory for Manufacturing System EngineeringShaanxi Key Laboratory of Intelligent Robots School of Mechanical Engineering Xi’an Jiaotong UniversityXi’an 710049China Qian Xuesen Honors College Xi’an Jiaotong UniversityXi’an 710049China

In recent years,materials with asymmetric mechanical response properties(mechanical Janus materials)have been found possess numerous potential applications,*** absorption and vibration *** this study,we propose a novel mechanical Janus lattice whose asymmetric mechanical response can be switched in orientation by a *** finite element analysis and experimental verification,this lattice exhibits asymmetric displacement responses to symmetric ***,with such a plug structure inside,individual lattices can switch the orientation of asymmetry and thus achieve reprogrammable design of a mechanical structure with chained *** reprogrammable asymmetry of this material will offer multiple functions in design of mechanical metamaterials.

关键词： Janus Non-reciprocity Programmability Mechanical metamaterial

Molecular insights into self-incompatibility systems:From evolution to breeding

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Plant Communications 2024年第2期5卷 23-45页

作者： Diyang zhang Yuan-Yuan Li Xuewei Zhao Cuili zhang Ding-Kun Liu Siren Lan Weilun yin zhong-Jian Liu Key Laboratory of National Forestry and Grassland Administration for Orchid Conservation and Utilization Fujian Agriculture and Forestry UniversityFuzhou 350002China College of Forestry Fujian Agriculture and Forestry UniversityFuzhou 350002China College of Biological Sciences and Technology Beijing Forestry UniversityBeijing 100083China

Plants have evolved diverse self-incompatibility(SI)systems for *** Darwin’s time,consid-erable progress has been made toward elucidating this unrivaled reproductive *** advances in interdisciplinary studies and applications of biotechnology have given rise to major break-throughs in understanding the molecular pathways that lead to SI,particularly the strikingly different SI mechanisms that operate in Solanaceae,Papaveraceae,Brassicaceae,and *** best-un-derstood SI systems,together with discoveries in other"nonmodel"SI taxa such as Poaceae,suggest a complex evolutionary trajectory of SI,with multiple independent origins and frequent and irreversible *** exploration of self-/nonself-discrimination signaling cascades has revealed a compre-hensive catalog of male and female identity genes and modifier factors that control *** also enable the characterization,validation,and manipulation of SI-related factors for crop improvement,helping to address the challenges associated with development of inbred ***,we review current knowledge about the evolution of SI systems,summarize key achievements in the molecular basis of pol-len‒pistil interactions,discuss potential prospects for breeding of SI crops,and raise several unresolved questions that require further investigation.

关键词： self-incompatibility S-RNase evolution genome editing crop improvement

SENP1 regulates IFN-γ-STAT1 signaling throug STAT3-SOCS3 negative feedback loop

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Journal of Molecular Cell Biology 2017年第2期9卷 144-153页

作者： Tingting Yu Yong Zuo Rong Cai Xian Huang Shuai Wu Chenxi zhang Y. Eugene Chin Dongdong Li Zhenning zhang Nansong Xia Qi Wang Hao Shen Xuebiao Yao zhong-yin zhang Song Xue Lei Shen Jinke Cheng Department of Biochemistry and Molecular Cell Biology Shanghai Key Laboratory for Tumor Microenvironment and Inflammation Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Developmental Genetics School of Basic Medical Sciences Nanjing Medical University Nanjing 211166 China Shanghai Institute of Immunology Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Institute of Health Sciences Chinese Academy of Sciences Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Microbiology University of Pennsylvania Perelman School of Medicine Philadelphia PA 19104 USA Anhui Key Laboratory of Cellular Dynamics Hefei National Laboratory for Physical Sciences at Nanoscale University of Science and Technology of ChinaHefei 230026 China Department of Biochemistry and Molecular Biology Indiana University School of Medicine Indianapolis IN 46202 USA Shanghai Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200127 China

Interferon-γ （IFN-γ） triggers macrophage for inflammation response by activating the intracellular JAK-STAT1 signaling. Suppressor of cytokine signaling 1 （SOCS1） and protein tyrosine phosphatases can negatively modulate IFN-γ signaling. Here, we identify a novel negative feedback loop mediated by STAT3-SOCS3, which is tightly controlled by SENP1 via de-SUMOylation of protein tyrosine phosphatase 1B （PTPIB）, in IFN-y signaling. SENP1-deficient macrophages show defects in IFN-γ signaling and M1 macrophage activation. PTP1B in SENP1-deficient macrophages is highly SUMOylated, which reduces PTP1B-induced de-phosphorylation of STAT3. Activated STAT3 then suppresses STAT1 activation via SOCS3 induction in SENP1-deficient macro- phages. Accordingly, SENP1-deficient macrophages show reduced ability to resist Listerio rnonocytogenes infection. These results reveal a crucial role of SENP1-controlled STAT1 and STAT3 balance in rnacrophage polarization.

关键词： IFN-γ macrophage SENP1 SUMOylation

New structure transistors for advanced technology node CMOS ICs

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National Science Review 2024年第3期11卷 24-41页

作者： Qingzhu zhang Yongkui zhang Yanna Luo Huaxiang yin Integrated Circuit Advanced Process R&D Center Institute of Microelectronics of Chinese Academy of Sciences(IMECAS) State key Lab of Fabrication Technologies for Integrated Circuits Institute of Microelectronics of Chinese Academy of Sciences School of Integrated Circuits University of Chinese Academy of Sciences

Over recent decades, advancements in complementary metal-oxide-semiconductor integrated circuits(ICs)have mainly relied on structural innovations in transistors. From planar transistors to the fin field-effect transistor(FinFET) and gate-all-around FET(GAAFET), more gate electrodes have been added to three-dimensional(3D) channels with enhanced control and carrier conductance to provide higher electrostatic integrity and higher operating currents within the same device footprint. Beyond the 1-nm node, Moore's law scaling is no longer expected to be applicable to geometrical shrinkage. Vertical transistor stacking, e.g. in complementary FETs(CFET), 3D stack(3DS) FETs and vertical-channel transistors(VFET), for enhanced density and variable circuit or system design represents a revolutionary scaling approach for sustained IC development. Herein, innovative works on specific structures, key process breakthroughs, shrinking cell sizes and design methodologies for transistor structure research and development are reviewed. Perspectives on future innovations in advanced transistors with new channel materials and operating theories are also discussed.

关键词： transistor CMOS GAAFET CFET 3DS FET

Nutrient transport following water transfer through the world's largest water diversion channel

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Journal of Environmental Sciences 2024年第1期135卷 703-714页

作者： Yuanhui Cheng Hong zhang Wei yin State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085 China Changjiang Water Resources Protection Institute Wuhan 430051China University of Chinese Academy of Sciences Beijing 100049China

Nutrient levels in the artificial channel constructed for the Middle Route Project are significant indicators of water quality safety and aquatic ecological integrity for this large,interbasin ***,the distribution and transport of nutrients along the channel were poorly *** on a time-series dataset as well as mass balance and material flow analysis methods,the water and nutrient transport fluxes in the Middle Route of the South-to-North Water Diversion Project were identified in this *** results indicate that the nutrient concentrations varied considerably with time,but there was no significant difference among the 30 stations of the main *** temperature difference was the major factor in the large fluctuations of water quality indicators over *** nutrient loadings varied with the water volume outputs from the main channel to the waterreceiving *** deposition was an important source of nutrients in the main channel,accounting for 9.13%,20.6%,and 0.635%of the nitrogen,phosphorus,and sulfur input from the Danjiangkou Reservoir,*** 2021,a net accumulation of 988 tons of N,29 tons of P,and 2,540 tons of S,respectively,were present in the main *** increase of these external and internal nutrient loadings would cause water quality fluctuation and deterioration in some local sections of the main *** study quantified the spatial and temporal patterns of nutrient transport in the Middle Route and revealed the ecological effects on the aquatic environment,assisting authorities on the project to develop effective water conservation strategies.

关键词： Nutrient transport Spatiotemporal patterns The Middle Route The South-to-North Diversion Project Hydro-ecological effects Water-receiving cities

An approach to estimate tree height using PolInSAR data constructed by the Sentinel-1 dual-pol SAR data and RVoG model

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Journal of Electronic Science and Technology 2024年第3期22卷 69-79页

作者： yin zhang Ding-Feng Duan School of Resources and Environment University of Electronic Science and Technology of ChinaChengdu611731China

We estimate tree heights using polarimetric interferometric synthetic aperture radar(PolInSAR)data constructed by the dual-polarization(dual-pol)SAR data and random volume over the ground(RVoG)*** the Sentinel-1 SAR dual-pol(SVV,vertically transmitted and vertically received and SVH,vertically transmitted and horizontally received)configuration,one notes that S_(HH),the horizontally transmitted and horizontally received scattering element,is *** S_(HH)data were constructed using the SVH data,and polarimetric SAR(PolSAR)data were *** proposed approach was first verified in simulation with satisfactory *** was next applied to construct PolInSAR data by a pair of dual-pol Sentinel-1A data at Duke Forest,North Carolina,*** to local observations and forest descriptions,the range of estimated tree heights was overall *** the heights with the ICESat-2 tree heights at 23 sampling locations,relative errors of 5 points were within±30%.Errors of 8 points ranged from 30%to 40%,but errors of the remaining 10 points were>40%.The results should be encouraged as error reduction is *** instance,the construction of PolSAR data should not be limited to using SVH,and a combination of SVH and SVV should be ***,an ensemble of tree heights derived from multiple PolInSAR data can be considered since tree heights do not vary much with time frame in months or one season.

关键词： Constructed polarimetric SAR data Dual polarization Sentinel-1 SAR data Polarimetric interferometric SAR Random volume over the ground model Tree height estimation