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Epstein-Barr virus enhances proliferation of nasopharyngeal carcinoma via dysregulating iron metabolism

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Epstein-Barr virus enhances proliferation of nasopharyngeal ...

Downregulation of key genes involved in ketone body metabolism is associated with poor prognosis for clear cell renal cell carcinoma patients

2019年中国肿瘤标志物学术大会暨第十三届肿瘤标志物青年科学家论坛

作者： Zhao,Weilin Feng,Guofei zhong,suhua Liang,Yushan Gao,Xiaoyu Tong,Yan Zhou,Xiaoying Xiao,Xue Mo,Yingxi Huang,Guangwu Zhang,Zhe Department of Otolaryngology Head and Neck Surgery First Affiliated Hospital of Guangxi Medical University Life Science Institute Guangxi Medical University Department of Research Affiliated Tumor Hospital of Guangxi Medical University

Background:Nasopharyngeal carcinoma(NPC) is a common viral-associated neoplasm in southern *** iron overload may contribute to ***,how EBV modulate tumor malignant biological behavior via iron metabolism is still ***:We used the GCBI bioinformatics platform to analyze TFR1 and investigated TFR1 expression by qPCR and ***,we quantified the intracellular iron in NPC *** addition,the biological role of TFR1 in NPC was ***:We found that TFR1 was upregulated in head and neck cancer and NPC *** of TFR1 was associated with lymph node metastasis and poor *** iron was dramatically higher in EBV positive NPC cell ***,the dysregulated expression of TFR1 was more pronounced in EBV positive NPC cell *** of TFR1 in NPC cells increased cell proliferation and ***:Our results suggest that TFR1 is overexpressed in NPC and promoted cell proliferation and *** may involve in modulate tumorigenic behavior via iron metabolism in *** findings could provide new targets for NPC target therapy.

关键词： Nasopharyngeal carcinoma EBV iron metabolism TFR1

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Downregulation of key genes involved in ketone body metaboli...

用阜新煤矸石制备阿利特-硫铝酸盐水泥的试验研究

2019年中国肿瘤标志物学术大会暨第十三届肿瘤标志物青年科学家论坛

作者： Zhou,Xiaoying Cui,Wanmeng Luo,Wenqi Zhou,Xiaohui Lu,Yunliang Xu,Wenqing zhong,suhua Feng,Guofei Liang,Yushan Liang,Libin Mo,Yingxi Xiao,Xue Huang,Guangwu Matskova,Liudmila Zhang,Zhe Li,Ping Guangxi Medical University Immanuel Kant Baltic Federal University

Kidney is an important organ for ketone body ***,the role of abnormal ketone metabolism and its possible function in tumorigenesis of clear cell renal cell carcinoma (ccRCC) have not yet been *** differentially expressed key enzymes involved in ketone body metabolism,ACAT1,BDH2 and HMGCL,were screened out between ccRCC and normal kidney tissues using the GEO and TCGA databases.

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地质论评 2005年第5期51卷 600-605页

作者：王国平孙传敏张平萍王自有苏小丽钟素华成都理工大学地球科学学院 610059

我国大量堆存和正在排放的煤矸石,既是一种矿业排量最大的废弃物,又可以被认为是一种可利用的巨型资源。阜新煤矸石主要由石英、长石、伊利石等矿物组成,化学成分含60%～67%SiO2,13%～18%Al2O3,具有高硅低铝特征,属于目前难以利用煤矸... 详细信息

我国大量堆存和正在排放的煤矸石,既是一种矿业排量最大的废弃物,又可以被认为是一种可利用的巨型资源。阜新煤矸石主要由石英、长石、伊利石等矿物组成,化学成分含60%～67%SiO2,13%～18%Al2O3,具有高硅低铝特征,属于目前难以利用煤矸石。本文实验采用了C3S-C4A3S-C2S-C4AF体系,利用煤矸石的Al2O3煅烧成无水硫铝酸钙而不是铝酸三钙。添加BaSO4、CaF2和铬渣,使硅酸三钙和无水硫铝酸钙能在1300～1360℃共生,制备出了阿利特-硫铝酸盐水泥。水泥熟料在1360℃,保温1小时烧成。研制的煤矸石水泥3天和28天抗压强度分别达到了34.7～36.8MPa和52.2～54.4MPa,达到了525#早强型高性能水泥指标。

关键词：低铝煤矸石阜新 C3S—C4A3S—C2S—C4AF体系阿利特-硫铝酸盐水泥煤矸石水泥试验研究制备无水硫铝酸钙 Al2O3 C4A3S

老年人自身免疫性IgG4相关性肺疾病的多层螺旋CT表现

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实用医学影像杂志 2020年第6期21卷 603-605页

作者：钟素华李传旺邱清香福建省龙岩市第一医院放射科 364000

目的探讨老年人自身免疫性IgG4增高相关性疾病肺部受累的多层螺旋CT表现。方法回顾性分析该院8例经临床确诊的自身免疫性IgG4增高肺部受累患者的螺旋CT表现,总结其影像特征,所有患者均行256层螺旋CT扫描。结果4例不同程度肺间质性改变,... 详细信息

目的探讨老年人自身免疫性IgG4增高相关性疾病肺部受累的多层螺旋CT表现。方法回顾性分析该院8例经临床确诊的自身免疫性IgG4增高肺部受累患者的螺旋CT表现,总结其影像特征,所有患者均行256层螺旋CT扫描。结果4例不同程度肺间质性改变,4例伴多发小结节影,3例散在索条影及局限性肺气肿改变,轻度肺动脉高压1例,肺门及纵隔淋巴结钙化1例。其中1例肺部呈分叶状小结节并肺门、纵隔淋巴结肿大及肺内多发小结节影,手术前误诊为肺癌,后经病理及临床激素治疗后诊断为IgG4相关性肺疾病。结论老年人自身免疫性IgG4增高相关性疾病,肺部受累的MSCT表现多种多样,以炎性结节及肺部慢性纤维化表现多见,伴肺门及纵隔淋巴结肿大时应与肺癌鉴别。

关键词：老年人体层摄影术,螺旋计算机肺疾病免疫球蛋白g4相关性疾病

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转铁蛋白受体1在头颈肿瘤中的表达及其意义

广西医科大学学报 2019年第5期36卷 691-695页

作者：冯国飞梁瑜珊钟素华张哲广西医科大学第一附属医院耳鼻咽喉头颈外科

目的:观察转铁蛋白受体1(TFR1)在头颈肿瘤中的表达,并分析其表达水平与患者临床病理特征的关系。方法:通过挖掘cDNA表达谱芯片(GSE33205、GSE29330)和人类肿瘤基因组(TCGA)中头颈肿瘤的数据,比较TFR1在肿瘤组织和正常组织中的转录水平,... 详细信息

目的:观察转铁蛋白受体1(TFR1)在头颈肿瘤中的表达,并分析其表达水平与患者临床病理特征的关系。方法:通过挖掘cDNA表达谱芯片(GSE33205、GSE29330)和人类肿瘤基因组(TCGA)中头颈肿瘤的数据,比较TFR1在肿瘤组织和正常组织中的转录水平,用KM-plotter在线软件研究TFR1表达与患者总生存率关系,进一步用头颈肿瘤组织芯片免疫组化技术检测TFR1的蛋白表达情况。结果:生物信息分析结果提示,头颈肿瘤中TFR1的表达较正常对照组织明显上调(P<0.05),TFR1高表达患者的总生存率较低(HR=1.43;P=0.0084)。免疫组化结果提示TFR1在肿瘤组织中表达较正常上调(P<0.05),高表达TFR1的头颈肿瘤患者有不良的预后(更易发生转移、更高的T分期,P<0.05)。结论:TFR1在头颈肿瘤中表达上调,可能参与肿瘤的发生和发展。

关键词：铁转运蛋白受体1 头颈肿瘤生物信息学预后分子标志物

导数光谱微计算机程序设计及复方制剂中咖啡因含量的测定

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化学试剂 1986年第3期 189-190页

作者：王慧尹和平吴仲王素华北京市药品检验所

导数光谱法对有机混合物、混浊溶液的含量测定显示出了良好的优越性,但是目前国内所报导的有关导数方面的文章,都是使用带有导数附件的进口仪器,使它的推广应用受到了较大限制。鉴于目前进口仪器的数量有限,国产仪器又不带导数附件,而... 详细信息

导数光谱法对有机混合物、混浊溶液的含量测定显示出了良好的优越性,但是目前国内所报导的有关导数方面的文章,都是使用带有导数附件的进口仪器,使它的推广应用受到了较大限制。鉴于目前进口仪器的数量有限,国产仪器又不带导数附件,而用手计算工作量很大,为此我们设计了导数光谱定量分析的微计算机程序,用751紫外分光光度计及自记分光光度计对安钠咖(咖啡因、苯甲酸钠)注射液中咖啡因的含量进行了测定。对用导数附件作图法测得的结果与上述结果进行了比较,误差小于2%。

关键词：咖啡因无水微计算机苯甲酸钠嘌呤生物碱取代苯类杀菌剂导数光谱安钠咖注射液复方制剂

Multi boron-doping effects in hard carbon toward enhanced sodium ion storage

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Journal of Energy Chemistry 2025年第1期100卷 730-738页

作者： Peng Zheng Wang Zhou Ying Mo Biao Zheng Miaomiao Han Qin zhong Wenwen Yang Peng Gao Lezhi Yang Jilei Liu College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean Energy Hunan Province Key Laboratory for Advanced Carbon Materials and Applied Technology Hunan University Greater Bay Area Institute for Innovation Hunan University Changsha Research Institute of Mining & Metallurgy Co. LTD.

Hard carbon （HC） has been considered as promising anode material for sodium-ion batteries （SIBs）.The optimization of hard carbon’s microstructure and solid electrolyte interface （SEI） property are demonstrated effective in enhancing the Na+storage capability,however,a one-step regulation strategy to achieve simultaneous multi-scale structures optimization is highly ***,we have systematically investigated the effects of boron doping on hard carbon’s microstructure and interface chemistry.A variety of structure characterizations show that appropriate amount of boron doping can increase the size of closed pores via rearrangement of carbon layers with improved graphitization degree,which provides more Na+storage ***-situ Fourier transform infrared spectroscopy/electrochemical impedance spectroscopy （FTIR/EIS） and X-ray photoelectron spectroscopy （XPS） analysis demonstrate the presence of more BC3and less B–C–O structures that result in enhanced ion diffusion kinetics and the formation of inorganic rich and robust SEI,which leads to facilitated charge transfer and excellent rate *** a result,the hard carbon anode with optimized boron doping content exhibits enhanced rate and cycling *** general,this work unravels the critical role of boron doping in optimizing the pore structure,interface chemistry and diffusion kinetics of hard carbon,which enables rational design of sodium-ion battery anode with enhanced Na+storage performance.

关键词： X ray photoelectron spectroscopy

A new method for preparation of template DNA for PCR from special plant materials

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Chinese Science Bulletin 2002年第9期47卷 725-727页

作者： HUANG Yelin SHI suhua zhong Yang TAN Fengxiao Key Laboratory of Gene Engineering of the Ministry of Education School of Life SciencesZhongshan UniversityGuangzhou 510275China Key Laboratory for Biodiversity Science and Ecological Engineering of the Ministry of Education School of Life SciencesFudan UniversityShanghai 200433China

A simple method for preparation of template DNA suitable for PCR amplification from herbarium samples and plant tissues rich in byproducts, e.g. polysaccha-rides, tannins, polyphenolic, and terpenoids compounds, is described. The total DNA from regular extraction procedure is absorbed by a small amount of glass powder and the final precipitation of glass powder is used directly as a template for PCR. Taking six plant taxa, including the herbarium specimens of Lythraceae collected from Namibia in 1957 and the silicon-dried leaf tissue from mangrove plants (Rhizo-phoraceae and Combretaceae) rich in by-products as examples, the PCR products, including nrDNA ITS regions and cpDNA rbcL gene, amplified following the regular and new methods respectively are compared. Our method provides a simple, rapid and economic approach to purify and prepare template DNA for PCR from special plant materials.

关键词： template DNA for PCR DNA purification nrDNA ITS regions cpDNA rbcL gene.

Effect of CuO on the Formation Mechanism of Calcium Sulphoaluminate

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Journal of Wuhan University of Technology(Materials Science) 2008年第4期23卷 518-521页

作者： MA suhua SHEN Xiaodong HUANG Yeping zhong Baiqian College of Materials Science and Engineering.Nanjing University of Technology Nanjing 210009 China

Calcium sulphoaluminate was prepared with chemical reagents in this paper. The formation mechanism of calcium sulphoaluminate and effect of CuO on the formation mechanism of calcium sulphoaluminate were investigated by the chemical analysis, X-ray diffraction （XRD）, and differential scanning calorimetry （DSC）. The results show that there are three ways in the formation of calcium sulphoaluminate. CuO can promote the decomposition of calcium carbonate and decrease the formation temperature of calcium sulphoaluminate（C4A3S）. When the burning temperature is below 1 000 ℃, the addition of CuO can promote the formation of calcium sulphoaluminate, while CuO can not favor the formation of calcium sulphoaluminate above 1 000 ℃.

关键词： copper oxide calcium sulphoaluminate formation mechanism