Downregulation of key genes involved in ketone body metabolism is associated with poor prognosis for clear cell renal cell carcinoma patients
作者单位:Guangxi Medical University Immanuel Kant Baltic Federal University
会议名称:《2019年中国肿瘤标志物学术大会暨第十三届肿瘤标志物青年科学家论坛》
会议日期:2019年
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要:Kidney is an important organ for ketone body ***,the role of abnormal ketone metabolism and its possible function in tumorigenesis of clear cell renal cell carcinoma (ccRCC) have not yet been *** differentially expressed key enzymes involved in ketone body metabolism,ACAT1,BDH2 and HMGCL,were screened out between ccRCC and normal kidney tissues using the GEO and TCGA databases.