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China Foundry 2024年第1期21卷 51-59页

作者： Dong Pan Qing-tao Guo Kai-lun Zhang Fu-zhi yu yu-ying Li yu-bao Xiao State Key Laboratory of Metal Materials for Marine Equipment and Application Anshan 114009LiaoningChina Ansteel Beijing Research Institute Co. Ltd.Beijing 102200China

Electromagnetic stirring is one of the widely applied techniques to modify the quality of casting *** from conventional rotate stirring,the helical stirring is more professional in assisting multi-dimensional flow of molten metal and eliminating solidification *** this study,the single-winding helical stirring(SWHS)was introduced,offering advantages such as smaller volume and lower electromagnetic shielding compared to traditional helical stirring *** a comprehensive numerical simulation,the stirring parameters of SWHS were adjusted to yoke inclination angle of 43°and frequency of 12 *** higher electromagnetic force and flow velocity in drawing direction,as well as the lower temperature gradient induced by the SWHS,are positive factors for homogeneous solidification of *** experimental results on Al-8%Si alloy and 0.4%C-1.1%Mn steel demonstrate that compared to rotate stirring,the SWHS process can induce better billet quality and is more effective in accelerating the equiaxed expansion and reducing element *** SWHS process can enhance the equiaxed ratio of the billet by 58.3%and reduce segregation degree of carbon element by 10.97%.Consequently,SWHS holds great promise as a potential approach for improving the quality of continuous casting billets.

关键词： billet electromagnetic stirring helical solidification element segregation numerical simulation

High uniformity and stability of 1S1R directly stacked for high-density cross-point memory applications

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Rare Metals 2022年第11期41卷 3671-3676页

作者： zhi-ying yu Jia-Yi Zhao Guo-Kun Ma Ao Chen Da-Lei Chen Yi-Heng Rao Hao Wang Hubei Yangtze Memory Laboratories Wuhan430205China School of Microelectronic Hubei UniversityWuhan430062China School of Physics and Technology Wuhan UniversityWuhan430072China

In this letter,the Ti-doped NbO_(x)-based selector is applied to SiNOx-based resistive random-access memory(RRAM),forming Pt/NbOx(Ti-doped)/SiNO_(x)/Ti one selector-one RRAM device(1S1R),to suppress the sneak path *** fabricated 1S1R exhibits stable direct current(DC)endurance(>200 cycles),suitable memory window(>40),matched selectivity(>40)and high uniformity of switching parameters.

关键词： Ti stability high

Predator-prey encounters:deciphering the robbery relationship between highwayman flies and their ant victims

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Integrative Zoology 2024年第2期19卷 253-261页

作者： ying ZHAO yulong yu zhi CHEN ying LI Huidan TENG Guillaume CHOMICKI Chuntian ZHANG Gao CHEN yunnan Key Laboratory for Integrative Conservation of Plant Species with Extremely Small Populations KunmingChina CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunmingChina College of Life Science Shenyang Normal UniversityShenyangChina School of Ecology and Environmental Science Yunnan UniversityKunmingChina University of Chinese Academy of Sciences BeijingChina Ecology and Evolutionary Biology School of BiosciencesAlfred Denny BuildingUniversity of SheffieldWestern BankSheffieldUK

Examples of predator–prey interactions in which flies rob ants are *** date,this behavior has only been recorded in the genus Bengalia Robineau-Desvoidy(Bengaliinae,Diptera,Calliphoridae).These predatory flies ambush ants,and rob them of the food or offspring that they are ***,because of the rarity of this behavior,the reasons and consequences(evolutionary advantages)are unknown,and indeed,the behavior has been sometimes considered *** this study,we employed field investigations and behavioral analyses to investigate whether the sex of the fly Bengalia varicolor,or the weight and quality of the food carried by Pheidole nodus ants influenced fly–ant interactions in their natural *** show that food weight and quality influenced the behavior of *** independent of the fly’s *** behavior by the flies was more successful when the food robbed was of high-quality and light in ***,the weight of the food robbed modulated the escape distance the flies could carry *** then may affect the food quality and weight transported by the *** is a novel example of deciphering the relationship between highwayman flies and their ant *** the widespread distribution of Bengalia flies,we suggest that such interspecific predator–prey encounters may shape the robbery interactions and the carrying behavior of further ant species in nature.

关键词： Bengalia kleptoparasitism Pheidole predatory flies robbing

Beamline design for multipurpose muon beams at CSNS EMuS

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Nuclear Science and Techniques 2024年第5期35卷 1-12页

作者： Yang Hong ying-Peng Song Lu-Ping Zhou Jing-yu Tang zhi-Hao Zhou Nikolaos Vassilopoulos Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China University of Chinese Academy of Sciences Beijing 100049China Radiotherapy Physics and Technology Center Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China Xi’an Jiaotong University Health Science Center Xi’an 710049China Department of Radiation Oncology First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710049China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China

A new muon beam facility,called the Experimental Muon Source(EMuS),was proposed for construction at the China Spallation Neutron Source(CSNS).The design of the complex muon beamlines for the EMuS baseline scheme,which is based on superconducting solenoids,superferric dipoles and room-temperature magnets,is presented *** muon beams,including surface muons,decay muons and low energy muons,have been developed for multipurpose *** optics design and simulation results of the trunk beamline and branch beamlines are *** a proton beam power of 25 kW at a standalone target station that consists of a conical graphite target and high-field superconducting solenoids,the muon beam intensity in the trunk beamline varies from 10^(7)/s for surface muons to 10^(10)/s for high-momentum decay *** at the endstations,these values vary from 10^(5)/s for surface muons to 10^(8)/s for decay muons.

关键词： Surface muons Decay muons Muon beamline Superconducting solenoids Multi-channel electrostatic separator

Effects of dietary intervention on human diseases:molecular mechanisms and therapeutic potential

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1389-1422页

作者： yu-Ling Xiao yue Gong ying-Jia Qi zhi-Ming Shao Yi-Zhou Jiang Key Laboratory of Breast Cancer in Shanghai Department of Breast SurgeryFudan University Shanghai Cancer CenterShanghaiChina Department of Oncology Shanghai Medical CollegeFudanUniversityShanghai200032China

Diet,serving as a vital source of nutrients,exerts a profound influence on human health and disease ***,dietary interventions have emerged as promising adjunctive treatment strategies not only for cancer but also for neurodegenerative diseases,autoimmune diseases,cardiovascular diseases,and metabolic *** interventions have demonstrated substantial potential in modulating metabolism,disease trajectory,and therapeutic *** reprogramming is a hallmark of malignant progression,and a deeper understanding of this phenomenon in tumors and its effects on immune regulation is a significant challenge that impedes cancer *** intake,as a key environmental factor,can influence tumor *** evidence indicates that dietary interventions might affect the nutrient availability in tumors,thereby increasing the efficacy of cancer ***,the intricate interplay between dietary interventions and the pathogenesis of cancer and other diseases is *** encouraging results,the mechanisms underlying diet-based therapeutic strategies remain largely unexplored,often resulting in underutilization in disease *** this review,we aim to illuminate the potential effects of various dietary interventions,including calorie restriction,fasting-mimicking diet,ketogenic diet,protein restriction diet,high-salt diet,high-fat diet,and high-fiber diet,on cancer and the aforementioned *** explore the multifaceted impacts of these dietary interventions,encompassing their immunomodulatory effects,other biological impacts,and underlying molecular *** review offers valuable insights into the potential application of these dietary interventions as adjunctive therapies in disease management.

关键词： diseases metabolism potential

Engineering morphologies of yttrium oxide supported nickel catalysts for hydrogen production

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Rare Metals 2023年第1期42卷 176-188页

作者： Rong-Bin Zhang Zi-Ao Tu Shuai Meng Gang Feng Zhang-Hui Lu ying-zhi yu Tomas Ramirez Reina Fei-Yang Hu Xiao-Han Chen Run-Ping Ye Key Laboratory of Jiangxi Province for Environment and Energy Catalysis Institute of Applied ChemistrySchool of Chemistry and Chemical EngineeringNanchang UniversityNanchang330031China Chemistry Examination Department Patent OfficeChina National Intellectual Property AdministrationBeijing100088China College of Chemistry and Chemical Engineering Jiangxi Normal UniversityNanchang330022China Department of Chemical and Process Engineering University of SurreyGuildfordGU27XHUK Department of Inorganic Chemistry and Materials Sciences Institute University of Seville-CSICSeville41092Spain

The catalytic performance is highly related to the catalyst ***,a series of Ni nanoparticles supported on Y_(2)O_(3) with different morphologies were successfully synthesized via hydrothermal process screening different pH *** Ni/Y_(2)O_(3)catalysts were applied to efficiently produce CO_(x)-free H2through ammonia *** identify a significant impact of Y_(2)O_(3)supports on nickel nanoclusters sizes and *** experimental results show that Ni/Y11 catalyst achieves 100% ammonia decomposition conversion under a gas hour space velocity(GHSV) of 12,000 ml·h^(-1)·gcat^(-1) and temperature of 650℃.Such a high level of activity over Ni/Y11 catalyst was attributed to a large specific surface area,appropriate alkalinity,and small Ni nanoparticles diameter with high dispersion.

关键词： Ammonia decomposition Hydrogen production Yttrium oxide morphology Ni catalysts Hydrothermal method

Micropulse transscleral laser therapy for secondary angle-closure glaucoma in nanophthalmos: a case report

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1381-1384页

作者： Ping yu Bai-yu Hu yu He Lin Jing Han-ying Fan Jing Shu Liu-zhi Zeng Chengdu First People’s Hospital Chengdu 610095Sichuan ProvinceChina Eye School of Chengdu University of TCM Chengdu 610075Sichuan ProvinceChina

Dear Editor,The choice of surgical intervention for nanophthalmos patients with secondary angle-closure glaucoma poses a challenging decision for *** nanophthalmos patients who have undergone filtration surgery or other intraocular procedures are more susceptible to severe complications,including choroidal effusion,malignant glaucoma,and explosive choroidal hemorrhage,all of which can lead to vision loss[1].This dilemma is particularly pronounced in patients with shorter axial *** transscleral laser therapy(M-TLT),also known as micropulse transscleral cyclophotocoagulation(MP-TSCPC),is a nonincisional laser therapy surgery for glaucoma[2].In 2015,Golan and Kurtz[3]were the first to report four patients with secondary angle-closure glaucoma in nanophthalmos with axial lengths ranging between 17 and 19 mm(mean 18 mm)who were successfully treated with M-TLT,and choroidal detachment was observed in all patients(recovery spontaneously in two patients and recovery after systemic steroid treatment in the other two),of which two had a slight decrease in visual acuity.

关键词： glaucoma surgery closure

Both gain-and loss-of-function variants of KCNA1 are associated with paroxysmal kinesigenic dyskinesia

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Journal of Genetics and Genomics 2024年第8期51卷 801-810页

作者： Wan-Bing Sun Jing-Xin Fu yu-Lan Chen Hong-Fu Li zhi-ying Wu Dian-Fu Chen Department of Medical Genetics and Center for Rare Diseases and Department of Neurologyand Zhejiang Key Laboratory of Rare Diseases for Precision Medicine and Clinical Translation in Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310009China Nanhu Brain-computer Interface Institute HangzhouZhejiang 314050China MOE Frontier Science Center for Brain Science and Brain-machine Integration School of Brain Science and Brain MedicineZhejiang UniversityHangzhouZhejiang 310012China

KCNA1 is the coding gene for Kv1.1 voltage-gated potassium-channelα*** variants of KCNA1 have been reported to manifest as paroxysmal kinesigenic dyskinesia(PKD),but the correlation between them remains unclear due to the phenotypic complexity of KCNA1 variants as well as the rarity of PKD *** the whole exome sequencing followed by Sanger sequencing,we screen for potential pathogenic KCNA1 variants in patients clinically diagnosed with paroxysmal movement disorders and identify three previously unreported missense variants of KCNA1 in three unrelated Chinese *** proband of one family(c.496G>A,p.A166T)manifests as episodic ataxia type 1,and the other two(c.877G>A,p.V293I and c.1112C>A,p.T371A)manifest as *** pathogenicity of these variants is confirmed by functional studies,suggesting that p.A166T and p.T371A cause a loss-of-function of the channel,while p.V293I leads to a gain-of-function with the property of voltage-dependent gating and activation kinetic *** reviewing the locations of PKD-manifested KCNA1 variants in Kv1.1 protein,we find that these variants tend to cluster around the pore domain,which is similar to ***,our study strengthens the correlation between KCNA1 variants and PKD and provides more information on genotype–phenotype correlations of KCNA1 channelopathy.

关键词： Paroxysmal kinesigenic dyskinesia KCNA1 Loss-of-function Gain-of-function Channelopathy Episodicataxiatype1

Equivalence between the internal observability and equation

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 89-97页

作者： LIU Wen-jun TU zhi-yu School of Mathematics and Statistics Nanjing University of Information Science and TechnologyNanjing 210044China

This paper is concerned with a third order in time linear Moore-Gibson-Thompson equation which describes the acoustic velocity potential in ultrasound wave *** by the work of Kaltenbacher,Lasiecka and Marchand(Control Cybernet.2011,40:971-988),we establish an observability inequality of the conservative problem,and then discuss the equivalence between the exponential stabilization of a dissipative system and the internal observational inequality of the corresponding conservative system.

关键词： Moore-Gibson-Thompson equation internal observability exponential stability

An analytical model for predicting sheet springback after V-bending

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第2期8卷 237-244页

作者： ZHANG Dong-juan CUI Zhen-shan CHEN zhi-ying RUAN Xue-yu National Mold ＆ Die CAD Engineering Research Center Shanghai Jiao Tong University Shanghai 200030 China

Springback is caused by the redistribution of stress in sheet material after the tooling is removed. Precise prediction of sheet springback is very important in die design. Based on Hill’s yielding criterion and plane strain condition, an analytical model is proposed in this paper which takes into account the effects of contact pressure, the length of bending arm between the punch and die, transverse stress, neutral surface shifting and sheet thickness thinning on the sheet springback of V-bending. The predicted results by this analytical model indicated that the contact pressure and transverse stress have much effect on the springback when the bending ratio (the ratio of punch radius to sheet thickness) is less than five. The contact pressure declined when the length of bending arm goes up, which means that shorter length of bending arm will result in larger springback. The effect of neutral surface shifting on the springback is less than that of contact pressure and decreases with the bending ratio. However, this research showed that the influence of thickness thinning on the springback can be ignored. Comparison with finite element method (FEM) simu-lating results shows that the predicted results by the analytical model accord well with simulation results by FEM. In addition to that, the bending ability—the limit bending ratio for a given sheet thickness and material properties was also determined.

关键词：回弹弯曲有限元分析冷冲压工艺