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The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish

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Neuroscience Bulletin 2020年第9期36卷 1023-1034页

作者： Jian Zhu Han-Tsing Wang Yu-Rong Chen Ling-Ya Yan Ying-Ying Han Ling-Yan liu Ying Cao zhi-zhi liu Hong A.Xu Institute of Life Science Nanchang UniversityNanchang 330031China School of Life Sciences Nanchang UniversityNanchang 330031China Jiangxi Provincial Collaborative Innovation Center for Cardiovascular Digestive and Neuropsychiatric DiseasesNanchang 330031China Department of Molecular and Cell Biology Tongji University School of Life Sciences and TechnologyShanghai 200092China Precise Genome Engineering Center School of Life SciencesGuangzhou UniversityGuangzhou 510006China

Joubert syndrome is characterized by unique malformation of the cerebellar *** than thirty Joubert syndrome genes have been identified,including ARL13 ***,its role in cerebellar development remains *** found that knockdown or knockout of arl13b impaired balance and locomotion in zebrafish *** cells were selectively reduced in the corpus cerebelli,a structure homologous to the mammalian *** cell progenitors were also selectively disturbed *** expression of atoh1 and ptf1,proneural genes of granule and Purkinje cells,respectively,were selectively down-regulated along the dorsal midline of the ***,wnt1,which is transiently expressed early in cerebellar development,was selectively ***,activating Wnt signaling partially rescued the granule cell defects in arl13b *** findings suggested that Arl13 b is necessary for the early development of cerebellar granule and Purkinje *** arl13b-deficient zebrafish can serve as a model organism for studying Joubert syndrome.

关键词： Joubert syndrome arl13b Cerebellum Development Granule cell Purkinje cell Wnt

Green synthesis of luminescent La-MOF nanoparticle from waste poly(ethylene terephthalate) for high-performance in Fe(Ⅲ) detection

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Rare Metals 2024年第8期43卷 3833-3843页

作者： zhi Gong zhi-Kui Dai zhi-Yue Dong Qiu-Xuan liu Valentin A.Milichko Hua-Jian liu Jie liu Ran Niu Jiang Gong Key Laboratory of Material Chemistry for Energy Conversion and Storage Hubei Key Laboratory of Material Chemistry and Service FailureHubei Engineering Research Center for Biomaterials and Medical Protective MaterialsSemiconductor Chemistry CenterSchool of Chemistry and Chemical EngineeringMinistry of EducationHuazhong University of Science and TechnologyWuhan 430074China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430073China Collaborative Innovation Center for Advanced Organic Chemical Materials Co-constructed by the Province and Ministry Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules and College of Chemistry and Chemical EngineeringHubei UniversityWuhan 430062China School of Physics and Engineering ITMO UniversitySt.Petersburg197101Russia School of Materials Science and Engineering Hubei UniversityWuhan430062China Guangdong Provincial Key Laboratory of Technique and Equipment for Macromolecular Advanced Manufacturing School of Mechanical and Automotive EngineeringKey Laboratory of Polymer Processing EngineeringMinistry of EducationSouth China University of TechnologyGuangzhou 510641China

Developing luminescent metal-organic frameworks(MOFs) capable of high-efficiency Fe^(3+)sensing has aroused great attraction in the fields of biology,chemistry,***,previous solvothermal methods are limited by organic solvent usage,time consuming,high pressure,and high-energy ***,we propose the waste-toMOF strategy towards the scale-up production of La-MOF nanoparticles through the ball milling of recycled poly(-ethylene terephthalate)(PET) bottles and La(NO_(3))_(3)·_(6)H_(2)*** goes on alkaline hydrolysis to form 1,4-benzenedicarboxylic acid sodium salt(Na_(2)BDC) and ethylene glycol by ball ***,BDC reacts with La^(3+)to form *** as-prepared La-MOF crystal nanoparticles possess a rod-like morphology with the size of few hundred ***,La-MOF nanoparticles display high selectivity and sensitivity for Fe^(3+)*** quenching constant and limit of detection are 5.29×10^(3)(mol·L^(-1))^(-1) and 0.147 μmol·L^(-1),respectively,thus surpassing many advanced Fe^(3+) *** to the result of density functional theory,the high Fe^(3+) detection performance of La-MOF is related to the complexing of Fe^(3+)with La-MOF,which leads to the gradual dissociation of the coordination bond between terephthalic acid and La^(3+).It is anticipated that the mechanochemistry milling-based wasteto-MOF strategy provides a new platform for the massive production of functional MOFs in a green manner.

关键词： Metal-organic framework Waste polyester Mechanochemistry milling Fluorescence sensor

Research progress on micro-force measurement of a hydrate particle system

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Petroleum Science 2024年第4期21卷 2169-2183页

作者： Qiang Luo Wei Li zhi-Hui liu Feng Wang zhi-Chao liu Fu-Long Ning Faculty of Engineering China University of Geosciences (Wuhan) Suzhou Laboratory

It remains a great challenge to understand the hydrates involved in phenomena in practical oil and gas systems. The adhesion forces between hydrate particles, between hydrate particles and pipe walls, and between hydrate particles and reservoir particles are essential factors that control the behaviors of clathrate hydrates in different applications. In this review, we summarize the typical micro-force measurement apparatus and methods utilized to study hydrate particle systems. In addition, the adhesion test results, the related understandings, and the applied numerical calculation models are systematically discussed.

关键词： Clathrate hydrates Hydrate particle Micro-force measurements Adhesion Interactions

Equivalence between the internal observability and equation

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 89-97页

作者： liu Wen-jun TU zhi-yu School of Mathematics and Statistics Nanjing University of Information Science and TechnologyNanjing 210044China

This paper is concerned with a third order in time linear Moore-Gibson-Thompson equation which describes the acoustic velocity potential in ultrasound wave *** by the work of Kaltenbacher,Lasiecka and Marchand(Control Cybernet.2011,40:971-988),we establish an observability inequality of the conservative problem,and then discuss the equivalence between the exponential stabilization of a dissipative system and the internal observational inequality of the corresponding conservative system.

关键词： Moore-Gibson-Thompson equation internal observability exponential stability

Growth process,defects,and dopants of bulkβ-Ga_(2)O_(3)semiconductor single crystals

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China Foundry 2024年第5期21卷 491-506页

作者： Yan-shen Wang Ming-zhi Zhu Yuan liu School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology(Ministry of Education) Beijing 100084China

β-gallium oxide(β-Ga2O3),as the typical representative of the fourth generation of semiconductors,has attracted increasing attention owing to its ultra-wide bandgap,superior optical properties,and excellent tolerance to high temperature and *** to the single crystals of other semiconductors,high-quality and large-sizeβ-Ga_(2)O_(3)single crystals can be grown with low-cost melting methods,making them highly *** this review,the growth process,defects,and dopants ofβ-Ga_(2)O_(3)are primarily ***,the growth process(e.g.,decomposition,crucible corrosion,spiral growth,and development)ofβ-Ga_(2)O_(3)single crystals are summarized and compared in ***,the defects ofβ-Ga_(2)O_(3)single crystals and the influence of defects on Schottky barrier diode(SBD)devices are emphatically ***,the influences of impurities and intrinsic defects on the electronic and optical properties ofβ-Ga_(2)O_(3)are also briefly *** this comprehensive analysis,the article offers a concise summary of the current state,challenges and prospects ofβ-Ga_(2)O_(3)single crystals.

关键词： β-Ga_(2)O_(3) single-crystal growth defects dopants semiconductor

Revolution in thermoelectric cooling using PbSe thermoelectrics by grid plainification

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Science China Materials 2024年第5期67卷 1672-1673页

作者： Xiao-Lei Shi Qingfeng liu zhi-Gang Chen School of Chemistry and Physics ARC Research Hub in Zero-emission Power Generation for Carbon Neutralityand Centre for Materials ScienceQueensland University of TechnologyBrisbaneQueensland4000Australia State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing211816China

Thermoelectric materials and devices enable direct conversion between heat and electricity,holding potential applications in thermoelectric power generation,localized cooling,and electronic thermal management[1].Howev... 详细信息

关键词： enable thermoelectric constrained

Quasi-2D weak lensing cosmological constraints using the PDF-SYM method

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Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 44-58页

作者： Zhenjie liu Jun Zhang Hekun Li zhi Shen Cong liu Department of Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Key Laboratory for Particle Physics and Cosmology Shanghai 200240China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China

Cosmic shear statistics,such as the two-point correlation function(2PCF),can be evaluated with the PDF-SYM method instead of the traditional weighted-sum *** makes use of the full PDF information of the shear estimators,and does not require weightings on the shear estimators,which can in principle introduce additional systematic *** work presents our constraints on S8and?mfrom the shear-shear correlations using the PDF-SYM *** data we use is from the z-band images of the Dark Energy Camera Legacy Survey(DECa LS),which covers about 10000 deg2with more than 100 million *** shear catalog is produced by the Fourier Quad method,and well tested on the real data itself with the field-distortion *** main approach is called quasi-2D as we do use the photo-z information of each individual galaxy,but without dividing the galaxies into redshift *** mainly use galaxy pairs within the redshift interval between 0.2 and 1.3,and the angular range from 4.7 to 180 *** analysis yields S8=0.762±0.026 and?m=0.234±0.075,with the baryon effects and the intrinsic alignments *** results are robust against redshift *** check the consistency of our results by deriving the cosmological constraints from auto-correlations ofγ1andγ2separately,and find that they are consistent with each other,but the constraints from theγ1component are much weaker than that fromγ*** implies a much worse data quality ofγ1,which is likely due to additional shear uncertainties caused by CCD electronics(according to the survey strategy of DECa LS).We also perform a pure 2D analysis,which gives S8=0.81_(-0.04)^(+0.03)and?m=0.25_(-0.05)^(+0.06).Our findings demonstrate the potential of the PDF-SYM method for precision cosmology.

关键词： weak lensing shear-shear correlations cosmological parameters observations analysis

Magnetic emission intensity enhancement for amorphous alloys by constructing a multi-phase structure withα-Fe nanocrystals

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Nano Research 2024年第7期17卷 6630-6637页

作者： Ke liu zhi Qin Jie Shen zhi Cheng Shiyue You Liang Ma Jing Zhou Wen Chen State Key Laboratory of Advanced Technology for Materials Synthesis and Processing School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070China Sanya Science and Education Innovation Park Wuhan University of TechnologySanya 572024China Hubei Longzhong Laboratory Wuhan University of Technology Xiangyang Demonstration ZoneXiangyang 441000China

The perturbation in the magnetic field generated by the rotation or oscillation of magnetic domains in magnetic materials can emit low-frequency electromagnetic waves,which are expected to be used in low-frequency ***,the magnetic emission intensity,defined by the perturbation ability,of current commercially applied amorphous alloys,such as Metglas,cannot meet the application requirements for low-frequency antennas due to the domain motion energy ***,a multi-phase Metglas amorphous alloy was constructed by incorporatingα-Fe nanocrystals using rapid annealing to manipulate the domain *** was found that 3.89 times higher magnetic emission intensity is obtained compared to the pristine due to the synergism of the deformation and displacement ***,the low-frequency magnetic emission performance verification was carried out by preparing magnetoelectric composites as the antenna vibrator by assembling the alloy and macro piezoelectric fiber composites(MFC).Enhancements of magnetic emission intensity are found at 93.3%and 49.2%at the first and second harmonic frequencies compared with the unmodified alloy ***,the approach leads to the development of high-performance communication with a novel standard for evaluation.

关键词： multi-phase amorphous alloys magnetic emission intensity enhancing mechanism magnetic domain pinning theory Jiles-Atherton model analysis

SNR-adaptive deep joint source-channel coding scheme for image semantic transmission with convolutional block attention module

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The Journal of China Universities of Posts and Telecommunications 2024年第1期31卷 1-11页

作者： Yang Yujia liu Yiming Zhang Wenjia Zhang zhi State Key Laboratory of Networking and Switch Technology Beijing University of Posts and TelecommunicationsBeijing 100876China

With the development of deep learning(DL),joint source-channel coding(JSCC)solutions for end-to-end transmission have gained a lot of *** deep JSCC schemes support dynamically adjusting the rate according to different channel conditions during transmission,enhancing robustness in dynamic wireless ***,most of the existing adaptive JSCC schemes only consider different channel conditions,ignoring the different feature importance in the image processing and *** uniform compression of different features in the image may result in the compromise of critical image details,particularly in low signal-to-noise ratio(SNR)*** address the above issues,in this paper,a dual attention mechanism is introduced and an SNR-adaptive deep JSCC mechanism with a convolutional block attention module(CBAM)is proposed,in which matrix operations are applied to features in spatial and channel dimensions *** proposed solution concatenates the pooling feature with the SNR level and passes it sequentially through the channel attention network and spatial attention network to obtain the importance evaluation *** show that the proposed solution outperforms other baseline schemes in terms of peak SNR(PSNR)and structural similarity(SSIM),particularly in low SNR scenarios or when dealing with complex image content.

关键词： semantic communication joint source-channel coding image transmission