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Selective CO_(2)electroreduction to formate over oxide-derived In nanosheets under industrial-current-density

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Rare Metals 2024年第11期43卷 6105-6112页

作者： Shan Zhu Yue Zhao Tai-Yun Zhu zhi-xin sun Feng Zhu Jun Cao Feng-Xiang Ma Xiao-dong Li Xiao-Jing Zhang Yong-Fu sun State Grid Anhui Electric Power Research Institute Hefei 230601China Max Planck Institute of MIcrostructure Physics Halle 06120Germany Hefei National Research Center for Physical Sciences University of Science and Technology of ChinaHefei 230026China

The strategy for converting CO_(2)into high-value chemicals through electroreduction is feasible and promising;however,its selectivity and current densities are highly dependent on the selection and modulation of ***,In_(2)O_(3)nanosheets were successfully fabricated and then converted into oxide-derived In nanosheets under the same CO_(2)electroreduction condition,where the in-situ X-ray diffraction and in-situ Raman results clearly revealedthe surface dynamic regulation process.

关键词： process oxide sheets

SARM1 participates in axonal degeneration and mitochondrial dysfunction in prion disease

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Neural Regeneration Research 2022年第10期17卷 2293-2299页

作者： Meng-Yu Lai Jie Li Xi-Xi Zhang Wei Wu zhi-Ping Li zhi-xin sun Meng-Yang Zhao Dong-Ming Yang Dong-Dong Wang Wen Li De-Ming Zhao Xiang-Mei Zhou Li-Feng Yang National Animal Transmissible Spongiform Encephalopathy Laboratory College of Veterinary MedicineChina Agricultural UniversityBeijingChina

Prion disease represents a group of fatal neurogenerative diseases in humans and animals that are associated with energy loss,axonal degeneration,and mitochondrial *** degeneration is an early hallmark of neurodegeneration and is triggered by *** found that depletion or dysfunctional mutation of SARM1 protected against NAD+loss,axonal degeneration,and mitochondrial functional disorder induced by the neurotoxic peptide ***+supplementation rescued prion-triggered axonal degeneration and mitochondrial dysfunction and SARM1 overexpression suppressed this protective ***+supplementation in PrP106-126-incubated N2a cells,SARM1 depletion,and SARM1 dysfunctional mutation each blocked neuronal apoptosis and increased cell *** results indicate that the axonal degeneration and mitochondrial dysfunction triggered by PrP^(106-126) are partially dependent on SARM1 NADase *** pathway has potential as a therapeutic target in the early stages of prion disease.

关键词： axonal degeneration mitochondrial dysfunction NAD+metabolism NADase neurodegenerative disease prion disease SARM1 sterile alpha and TIR motif-containing 1

A simple physical mixing method for MnO2/MnO nanocomposites with superior Zn^2+storage performance

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Transactions of Nonferrous Metals Society of China 2020年第12期30卷 3347-3355页

作者： Xiao-bei ZANG Ling-tong LI zhi-xin sun Rabah BOUKHERROUB Jia-xin MENG Kun-peng CAI Qing-guo SHAO Ning CAO School of Materials Science and Engineering China University of Petroleum(East China)Qingdao 266580China University Lille CNRS UMR 8520-IEMNLilleF-59000France

MnO2/MnO cathode material with superior Zn^2+storage performance is prepared through a simple physical mixing *** MnO2/MnO nanocomposite with a mixed mass ratio of 12:1 exhibits the highest specific capacity(364.2 mA·h/g at 0.2C),good cycle performance(170.4 mA·h/g after 100 cycles)and excellent rate performance(205.7 mA·h/g at 2C).Analysis of cyclic voltammetry(CV)data at various scan rates shows that both diffusioncontrolled insertion behavior and surface capacitive behavior contribute to the Zn2+storage performance of MnO2/MnO *** the capacitive behavior contributes more at high discharge rates,due to the short paths of ion diffusion and the rapid transfer of electrons.

关键词： zinc-ion battery MnO2/MnO cathode material physical mixing method reaction kinetics

三维石墨烯/苯胺-吡咯共聚复合物的制备及其超级电容性能

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材料导报 2017年第14期31卷 16-21,34页

作者：智新彭同江孙红娟汪建德西南科技大学材料科学与工程学院绵阳621010 西南科技大学分析测试中心绵阳621010 西南科技大学固体废物处理与资源化教育部重点实验室绵阳621010

以制备的氧化石墨凝胶和苯胺-吡咯共聚物为原料,将二者进行混合超声分散,再以其混合分散液为前驱体,采用一步水热法制得三维石墨烯/苯胺-吡咯共聚复合物(3DAP)。利用X射线衍射(XRD)、拉曼光谱(Raman)、傅里叶变换红外(FT-IR)光谱、扫描... 详细信息

以制备的氧化石墨凝胶和苯胺-吡咯共聚物为原料,将二者进行混合超声分散,再以其混合分散液为前驱体,采用一步水热法制得三维石墨烯/苯胺-吡咯共聚复合物(3DAP)。利用X射线衍射(XRD)、拉曼光谱(Raman)、傅里叶变换红外(FT-IR)光谱、扫描电镜(SEM)、透射电镜(TEM)和电化学测试等研究了复合物的结构、形貌及电化学性能。结果表明:3DAP拥有丰富的三维多孔网状结构,并且颗粒状的苯胺-吡咯共聚物能够均匀地分布于孔隙间;作为电极材料,该复合物在0.5A·g^(-1)电流密度下比电容可达628.5F·g^(-1),即使在大电流密度(20A·g^(-1))条件下仍可高达384F·g^(-1),且在1A·g^(-1)电流密度下经过1 000次的充放电循环后比容量保持率高达86.1%,表现出良好的倍率特性和循环稳定性,其超级电容性能远优于单纯的石墨烯以及苯胺-吡咯共聚物。

关键词：氧化石墨烯水热法苯胺-吡咯共聚物多孔网状结构超级电容性能

Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying sun Haoyan Li Dongqing sun Shaliu Fu Lei Gu xin Shao Qinqin Wang xin Dong Bin Duan Feiyang xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

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双因子自适应阈值的镜头边界检测算法

上海交通大学学报 2009年第11期43卷 1685-1688页

作者：方之昕孙锬锋蒋兴浩上海交通大学信息安全工程学院上海200240

针对传统镜头边界检测算法在阈值选取上的局限性,提出了基于镜头时间连续性的时间因子和基于镜头运动相关性的运动差异因子概念,并基于该双因子设定自适应阈值,将其运用于MPEG-2压缩域视频中.结果表明,该算法能够减少漏检和镜头运动造... 详细信息

针对传统镜头边界检测算法在阈值选取上的局限性,提出了基于镜头时间连续性的时间因子和基于镜头运动相关性的运动差异因子概念,并基于该双因子设定自适应阈值,将其运用于MPEG-2压缩域视频中.结果表明,该算法能够减少漏检和镜头运动造成的误检,有效提高镜头边界检测的准确率.

关键词：时间因子运动差异因子自适应阈值镜头边界检测

Staged dendrite suppression for high safe and stable lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 674-683页

作者： Jun Jiang Zhenjie Lu Yanwen Ding Shujun Liu zhijie Qi Tian Tang Yunfan Zhang zhiyuan Ma Jingwen sun Liang Xue Wenyao Zhang Pan Xiong xin Wang Junwu Zhu Yongsheng Fu Key Laboratory for Soft Chemistry and Functional Materials of Ministry of Education Nanjing University of Science and Technology Jiangsu Pylon Battery Co.Ltd

The unavoidable dendrite growth and shuttle effect have long been stranglehold challenges limiting the safety and practicality of lithium-sulfur ***,we propose a dual-action strategy to address the lithium dendrite issue in stages by constructing a multifunctional surface-negatively-charged nanodiamond layer with high ductility and robust puncture resistance on polypropylene （PP） *** uniformly loaded compact negative layer can not only significantly enhance electron transmission efficiency and promote uniform lithium deposition,but also reduce the formation of dendrite during early deposition *** importantly,under the strong puncture stress encountered during the deterioration of lithium dendrite growth under limiting current,the high ductility and robust puncture resistance（145.88 MPa） of as-obtained nanodiamond layer can effectively prevent short circuits caused by unavoidable lithium *** Li||Li symmetrical cells assembled with nanodiamond layer modified PP demonstrated a stable cycle of over 1000 h at 2 mA cm-2with a polarization voltage of only 29.3 ***,the negative charged layer serves as a physical barrier blocking lithium polysulfide ions,effectively mitigating capacity *** improved cells achieved a capacity decay of only 0.042%per cycle after 700 cycles at 3 C,demonstrating effective suppression of dendrite growth and capacity attenuation,showing promising prospect.

关键词： Lithium-sulfur batteries Staged dendrite suppression Shuttle effect Surface-negatively-charged nanodiamond

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渐开线插齿刀CAD专家系统的开发

四川大学学报（工程科学版） 2002年第2期34卷 85-88页

作者：王玫王杰贾志欣陶孙杰四川大学制造科学与工程学院四川成都610065

根据渐开线插齿刀设计的特点 ,分析了渐开线插齿刀设计的关键参数 ,即变位系数和齿数的合理选择 ,进而提出一种实用的渐开线插齿刀CAD的方法———渐开线插齿刀CAD专家系统的模式 ,并着重介绍了专家系统模式中的齿轮信息表示法和知识库... 详细信息

根据渐开线插齿刀设计的特点 ,分析了渐开线插齿刀设计的关键参数 ,即变位系数和齿数的合理选择 ,进而提出一种实用的渐开线插齿刀CAD的方法———渐开线插齿刀CAD专家系统的模式 ,并着重介绍了专家系统模式中的齿轮信息表示法和知识库的组织和管理。

关键词：渐开线插齿刀 CAD专家系统变位系数设计渐开线齿轮加工

不同避孕措施使用者生殖道人乳头瘤病毒感染检测

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毒理学杂志 2009年第1期23卷 22-24页

作者：吴玉璘姜志欣孙志明潘丽丁菊红李瑛江苏省生殖健康检验中心江苏省计划生育科学技术研究所江苏南京210036

目的了解不同避孕措施长期使用者生殖道人乳头状瘤病毒(HPV)感染的情况。方法采用聚合酶链反应(PCR)检测服用口服避孕药或使用宫内节育器5年以上的妇女226人宫颈分泌物中HPV DNA,研究对象按避孕措施分成1号片组、复方18-甲组和宫内节育... 详细信息

目的了解不同避孕措施长期使用者生殖道人乳头状瘤病毒(HPV)感染的情况。方法采用聚合酶链反应(PCR)检测服用口服避孕药或使用宫内节育器5年以上的妇女226人宫颈分泌物中HPV DNA,研究对象按避孕措施分成1号片组、复方18-甲组和宫内节育器组。结果三组研究对象的HPV总检出率为14.2%,HPV的检出率复方18-甲组最高,宫内节育器组最低,分别为复方18-甲组20.45%、1号片组11.11%、宫内节育器组8.77%,三组间的差异无统计学意义(P>0.05)。三组中HPV感染者的宫颈均有异常表现,但差异无统计学意义(P>0.05)。结论对有性生活,特别是长期使用避孕措施的妇女提供常规的宫颈涂片检查和HPV检测服务,有助于提高避孕措施使用者的身心健康。

关键词：口服避孕药宫内节育器人乳头状瘤病毒聚合酶链反应