检索结果-南通市图书馆

Impact of co-infections with enteric pathogens on children suffering from acute diarrhea in southwest China

Infectious Diseases of Poverty 2016年第1期5卷 534-546页

作者： Shun-Xian Zhang Yong-Ming Zhou Wen Xu Li-Guang Tian Jia-Xu Chen Shao-Hong Chen zhi-sheng dang Wen-Peng Gu Jian-Wen Yin Emmanuel Serrano Xiao-Nong Zhou National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025People’s Republic of China Key Laboratory for Parasite and Vector Biology Ministry of Health of ChinaWHO Collaborating Center for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghai 200025People’s Republic of China Yunnan Provincial Center for Disease Control and Prevention KunmingPeople’s Republic of China Centre for Environmental and Marine Studies Departamento de BiologíaUniversidade de AveiroAveiroPortugal Servei d’Ecopatologia de Fauna Salvatge Departament de Medicina i Cirurgia AnimalsUniversitat Autònoma de BarcelonaBellaterraSpain

Background:Acute diarrhea is a global health problem,resulting in high morbidity and mortality in *** has been suggested that enteric pathogen co-infections play an important role in gastroenteritis,but most research efforts have only focused on a small range of species belonging to a few pathogen *** study aimed to assess the impact of co-infections with a broad range of enteric pathogens on children aged below five years who suffer from acute diarrhea in southwest ***:A total of 1020 subjects(850 diarrhea cases and 170 healthy controls)were selected from four sentinel hospitals in Kunming,Yunnan province,southwest China,from June 2014 to July *** specimens were collected to detect five virus(rotavirus group A,RVA;norovirus,NoV;Sapovirus,SaV;astrovirus,As;and adenovirus,Ad),seven bacterial(diarrheagenic Escherichia coli,DEC;non-typhoidal Salmonella,NTS;Shigella spp.;Vibrio cholera;Vibrio parahaemolyticus;Aeromonas spp.;and Plesiomonas spp.),and three protozoan(Cryptosporidium spp.,Giardia lamblia,and Blastocystis hominis,***)species using standard microbiologic and molecular *** were analyzed using the partial least square regression technique and chi-square ***:At least one enteric pathogen was detected in 46.7%(n=397)of acute gastroenteritis cases and 13.5%(n=23)of healthy controls(χ^(2)=64.4,P<0.05).Single infection with RVA was associated with acute diarrhea(26.5%vs.5.8%,P<0.05).The prevalence of a single infection with *** in diarrhea cases was higher than in healthy controls(3.1%vs.0.5%,OR=4.7,95%CI:1.01–112.0).Single infection with NoV GII was not associated with diarrhea(4.4%vs.3.5%,OR=1.2,95%CI:0.5–3.3).Single infections with bacterial species were not *** prevalence of co-infections with two enteric pathogens in diarrhea cases was higher than in asymptomatic children(20.1%vs.5.3%,P<0.05).RVA-NoV GII was the most common co-infection in symptomatic children(4.4%),with it aggravating the

关键词： Co-infection Diarrhea Bacteria Virus Intestinal protozoa Children Severity Kunming Yunnan China

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Study roadmap for high-throughput development of easy to use and affordable biomarkers as diagnostics for tropical diseases:a focus on malaria and schistosomiasis

引用

Infectious Diseases of Poverty 2017年第1期6卷 1149-1156页

作者： Kokouvi Kassegne Ting Zhang Shen-Bo Chen Bin Xu zhi-sheng dang Wang-Ping Deng Eniola Michael Abe Hai-Mo Shen Wei Hu Takele Geressu Guyo Solomon Nwaka Jun-Hu Chen Xiao-Nong Zhou National Institute of Parasitic Diseases(NIPD) Chinese Centre for Disease Control and PreventionShanghai 200025People’s Republic of China WHO Collaborating Centre for Tropical Diseases National Centre for International Research on Tropical DiseasesKey Laboratory of Parasite and Vector Biology of the Chinese Ministry of HealthShanghai 200025People’s Republic of China Department of Microbiology and Microbial Engineering School of Life ScienceFudan UniversityShanghai 200433People’s Republic of China African Network for Drugs&Diagnostics Innovation(ANDI) Addis AbabaEthiopia

Background:Interventions are currently being used against‘infectious diseases of poverty’,which remain highly debilitating and deadly in most endemic countries,especially malaria,schistosomiasis,echinococcosis and African sleeping ***,major limitations of current‘traditional’methods for diagnosis are neither simple nor convenient for population surveillance,and showed low sensitivity and *** to novel technologies for the development of adequate and reliable tools are expressly needed.A collaborative project between African Network for Drugs and Diagnostics Innovation and partner institutions in Africa and China aims to screen suitable serological biomarkers for diagnostic pipelines against these‘diseases of the poor’.Methods:Parasite-specific exposed versus unexposed individuals were screened and sera or urine/stools were collected through case-control studies in China and African *** genes/open reading frames were selected,then will be cloned and cell-free expressed,quantified and *** antigens/epitopes will be probed and screened with sera from exposed or unexposed individuals using a high-throughput antigen screening platform as the study *** specificity and sensitivity of highly immunoreactive biomarkers will be evaluated as well,using enzyme-linked immunosorbent assays or ***:This roadmap explicitly unfolds the integrated operating procedures with focus on malaria and schistosomiasis,for the identification of suitable biomarkers that will aid the prioritization of diagnostics for population ***,there is need to further validate any new diagnostic through comparison with standard methods in field deployable tests for each *** expectations for the future are to seek regulatory approval and promote the use of diagnostics in endemic areas.

关键词： Malaria Schistosomiasis Neglected tropical diseases Immunoproteomics Protein microarray Serological biomarker Diagnosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dynamic coupling of ferrihydrite transformation and associated arsenic desorption/redistribution mediated by sulfate-reducing bacteria

引用

Journal of Environmental Sciences 2024年第1期135卷 39-50页

作者： Wenjing Zhou Huiyan Zhu Shiwen Hu Bowei Zhang Kun Gao zhi dang Chongxuan Liu State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control School of Environmental Science and EngineeringSouthern University of Science and TechnologyShenzhen 518055China The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters Ministry of EducationSouth China University of TechnologyGuangzhou 510006China

Sulfate-reducing bacteria play an important role in the geochemistry of iron(oxyhydr)oxide and arsenic(As)in natural environments;however,the associated reaction processes are yet to be fully *** this study,batch experiments coupled with geochemical,spectroscopic,microscopic,and thermodynamic analyses were conducted to investigate the dynamic coupling of ferrihydrite transformation and the associated As desorption/redistribution mediated by Desulfovibrio vulgaris(***).The results indicated that *** could induce ferrihydrite transformation via S^(2-)-driven and direct reduction *** the absence of SO_(4)^(2-),*** directly reduced ferrihydrite,and As desorption and re-sorption occurred simultaneously during the partial transformation of ferrihydrite to *** increase in SO_(4)^(2-)loading promoted the S^(2-)-driven reduction of ferrihydrite and accelerated the subsequent mineralogical *** the low and medium SO_(4)^(2-)treatments,ferrihydrite was completely transformed to a mixture of magnetite and mackinawite,which increased the fraction of As in the residual phase and stabilized *** the high SO_(4)^(2-)treatment,although the replacement of ferrihydrite by only mackinawite also increased the fraction of As in the residual phase,22.1%of the total As was released into the solution due to the poor adsorption affinity of As to mackinawite and the conversion of As^(5+)to As^(3+).The mechanisms of ferrihydrite reduction,mineralogy transformation,and As mobilization and redistribution mediated by sulfate-reducing bacteria are closely related to the surrounding SO_(4)^(2-)*** results advance our understanding of the biogeochemical behavior of Fe,S,and As,and are helpful for the risk assessment and remediation of As contamination.

关键词： Sulfate-reducing bacteria Arsenic Ferrihydrite Transformation Redistribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Mo and cold forging deformation on strength and ductility of cobalt-based alloy L605

引用

Journal of Iron and Steel Research International 2024年第7期31卷 1811-1823页

作者： Zhong-lin Wang zhi-hua Gong Quan Li Han-sheng Bao School of Materials and Metallurgy Inner Mongolia University of Science and TechnologyBaotou 014017Inner MongoliaChina Institute of Special Steels Central Iron and Steel Research Institute Co.Ltd.Beijing 100081China

Mo element was added to cobalt-based alloy L605,and cold forging deformation was *** effects of the addition and cold forging deformation on the microstructure and mechanical properties of the alloy were studied by thermodynamic calculation,electron backscatter diffraction,transmission electron microscopy,and X-ray *** stacking fault energy(SFE)of the alloy decreased after the addition,and the formation of stacking faults and intersections were promoted to improve the strength and *** tensile strength of the alloy with Mo increased from 1190 to 1702 MPa after 24%cold deformation,producing significant work *** strengthening mechanism is strain-induced martensitic transformation(SIMT)and deformation *** alloy,combined with Mo and after 24%deformation,had both high strength and ductility in comparison with the original cobalt-based alloy *** is attributed to the lower SFE which caused the increase in stacking fault *** the tensile process,theε-hcp phase was easily generated at the stacking fault to reduce the stress concentration and increase the *** SIMT by adjusting the density of stacking faults can improve the mechanical properties of cobalt-based ***ε-hcp phase,the interaction between deformation twins and dislocations,and the interaction between e-hcp phases during cold forging deformation caused local stress concentration,lowering ductility and toughness.

关键词： Cobalt-based alloy-Stacking fault energy Strain-induced martensitic transformation Deformation twin Cold forging deformation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Achieving Synergistic Improvement in Dielectric and Energy Storage Properties of All-Organic Poly(Methyl Methacrylate)-Based Copolymers Via Establishing Charge Traps

引用

Energy & Environmental Materials 2024年第2期7卷 312-323页

作者： Guanghu He Huang Luo Chuanfang Yan Yuting Wan dang Wu Hang Luo Yuan Liu sheng Chen Key Laboratory of Polymeric Materials and Application Technology of Hunan Province College of Chemistry Xiangtan University State Key Laboratory of Powder Metallurgy Central South University Guangdong University of Petrochemical Technology

How to achieve synergistic improvement of permittivity（εr） and breakdown strength（Eb） is a huge challenge for polymer ***,for the first time,the π-conjugated comonomer（MHT） can simultaneously promote theεrand Ebof linear poly（methyl methacrylate）(PMMA) *** PMMA-based random copolymer films(P（MMA-co-MHT）),block copolymer films（PMMA-b-PMHT）,and PMMA-based blend films were prepared to investigate the effects of sequential structure,phase separation structure,and modification method on dielectric and energy storage properties of PMMA-based dielectric *** a result,the random copolymer P（MMA-coMHT） can achieve a maximum εrof 5.8 at 1 kHz owing to the enhanced orientation polarization and electron *** electron injection and charge transfer are limited by the strong electrostatic attraction ofπ-conjugated benzophenanthrene group analyzed by the density functional theory（DFT）,the discharge energy density value of P（MMA-co-PMHT）containing 1 mol% MHT units with the efficiency of 80% reaches15.00 J cm-3at 872 MV m-1,which is 165% higher than that of pure *** study provides a simple and effective way to fabricate the high performance of polymer dielectrics via copolymerization with the monomer of P-type semi-conductive polymer.

关键词： dielectric capacitor electrical properties energy density polymer dielectric semiconductor polymer

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Endoscopic band ligation or endoscopic tissue adhesive injection in the treatment of gastric varices:Which is better?

引用

World Journal of Gastroenterology 2024年第21期30卷 2827-2828页

作者： Li-zhi Yi sheng-Bing Zhao Department of Gastroenterology The People’s Hospital of LeshanLeshan 614000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalThe Second Military Medical University/Naval Medical UniversityShanghai 200433China

The combination of endoscopic ultrasound with endoscopic treatment of type 1 gastric variceal hemorrhage may improve the robustness and generalizability of the findings in future ***,the esophageal varices should also... 详细信息

关键词： Gastric varices Esophageal varices Endoscopic band ligation Endoscopic tissue adhesive injection Endoscopic ultrasound

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Towards designing high mechanical performance low-alloyed wrought magnesium alloys via grain boundary segregation strategy:A review

引用

Journal of Magnesium and Alloys 2024年第5期12卷 1774-1791页

作者： zhi Zhang Jinshu Xie Jinghuai Zhang Xu-sheng Yang Ruizhi Wu Key Laboratory of Superlight Material and Surface Technology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China State Key Laboratory of Ultra-Precision Machining Technology Department of Industrial and Systems EngineeringThe Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518060China

Low-alloyed magnesium(Mg)alloys have emerged as one of the most promising candidates for lightweight ***,their further application potential has been hampered by limitations such as low strength,poor plasticity at room temperature,and unsatisfactory *** address these challenges,grain refinement and grain structure control have been identified as crucial factors to achieving high performance in low-alloyed Mg *** effective way for regulating grain structure is through grain boundary(GB)*** review presents a comprehensive summary of the distribution criteria of segregated atoms and the effects of solute segregation on grain size and growth in Mg *** analysis encompasses both single element segregation and multi-element co-segregation behavior,considering coherent interfaces and incoherent ***,we introduce the high mechanical performance low-alloyed wrought Mg alloys that utilize GB segregation and analyze the potential impact mechanisms through which GB segregation influences materials *** upon these studies,we propose strategies for the design of high mechanical performance Mg alloys with desirable properties,including high strength,excellent ductility,and good formability,achieved through the implementation of GB *** findings of this review contribute to advancing the understanding of grain boundary engineering in Mg alloys and provide valuable insights for future alloy design and optimization.

关键词： Magnesium alloys Grain boundary segregation High strength High plasticity High formability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Development of a prognostic scoring system for hepatic vena cava Budd-Chiari syndrome with hepatocellular carcinoma

引用

Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 370-375页

作者： sheng-Yan Liu Lu-Hao Li Zhao-Chen Liu Su-Xin Li Xiao-Wei dang Department of Hepatopancreatobiliary Surgery the First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Budd-Chiari Syndrome Diagnosis and Treatment Center of Henan Province Zhengzhou 450052China

Background:Hepatocellular carcinoma(HCC)is a serious complication of hepatic vena cava Budd-Chiari syndrome(HVC-BCS)that significantly reduces the survival time of *** study aimed to analyze the prognostic factors influencing the survival of HVC-BCS patients with HCC and to develop a prognostic scoring ***:The clinical and follow-up data of 64 HVC-BCS patients with HCC who received invasive treatment at the First Affiliated Hospital of Zhengzhou University between January 2015 and December 2019 were retrospectively ***-Meier curves and log-rank tests were used to analyze the survival curve of patients and the difference in prognoses between the *** and multivariate Cox regression analyses were performed to analyze the influence of biochemical,tumor,and etiological characteristics on the total survival time of patients,and a new prognostic scoring system was developed according to the regression coefficients of the independent predictors in the statistical *** prediction efficiency was evaluated using the time-dependent receiver operating characteristics curve and concordance ***:Multivariate analysis showed that serum albumin level7 cm(HR=8.623,95%CI:3.771-19.715,P<0.001),and inferior vena cava stenosis(HR=3.612,95%CI:1.646-7.928,P=0.001)were independent predictors of survival.A prognostic scoring system was developed according to the above-mentioned independent predictors,and patients were classified into grades A,B,C and *** differences in survival were found among the four ***:This study successfully developed a prognostic scoring system for HVC-BCS patients with HCC,which is helpful for clinical evaluation of patient prognosis.

关键词： Budd-Chiari syndrome Hepatocellular carcinoma Prognostic factors Inferior vena cava stenosis Prognostic scoring system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nitrogen-doped carbon dots as photocatalysts for organic synthesis:Effect of nitrogen content on catalytic activity

引用

Nano Research 2024年第6期17卷 4825-4833页

作者： Kai-Kai Niu Chao-Qun Ma Rui-zhi Dong Hui Liu sheng-sheng Yu Ling-Bao Xing School of Chemistry and Chemical Engineering Shandong University of TechnologyZibo 255000China

Regulating the doping of carbon dots(CDs)and the generation of reactive oxygen species(ROS)is essential to selectively control their application in photocatalytic organic *** study successfully synthesized five newly developed nitrogen-doped carbon dots(CDs 1-5)with varying nitrogen content,which have the ability to generate ROS when exposed to light radiation,specifically superoxide anion radicals(O_(2)•-)and singlet oxygen(^(1)O_(2)).The utilization of the aforementioned nitrogen-doped CDs as photocatalysts enables the realization of their potential in facilitating efficient photocatalytic organic ***,it was observed that the photocatalytic efficiency exhibited a gradual decrease when the nitrogen content in the CDs *** order to provide more evidence for this claim,we employed a set of five CDs in the context of photocatalytic dehalogenation ofα-bromoacetophenone,photocatalytic oxidative coupling reaction of amines to imines,photooxidation reaction of sulfides to sulfoxides,and cross-dehydrogenation coupling(CDC)reaction,in which it was further observed that there was a steady decrease in the yields of photocatalytic organic reactions as the nitrogen content in CDs ***,CDs 1 exhibited the best photocatalytic efficiency,thereby reinforcing the hypothesis that a higher nitrogen content corresponds to a decreased catalytic *** study not only investigates the impact of the nitrogen content on the catalytic performance of CDs,but also offers valuable insights for the future utilization of CDs for photocatalytic organic reactions in water.

关键词： carbon dots nitrogen-doped reactive oxygen species photocatalysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interpretation and characterization of rate of penetration intelligent prediction model

引用

Petroleum Science 2024年第1期21卷 582-596页

作者： zhi-Jun Pei Xian-zhi Song Hai-Tao Wang Yi-Qi Shi Shou-Ceng Tian Gen-sheng Li College of Petroleum Engineering China University of Petroleum(Beijing)Beijing102249China State Key Laboratory of Petroleum Resources and Prospecting Beijing102249China Kunlun Digital Technology Co. Ltd.Beijing102206China

Accurate prediction of the rate of penetration(ROP)is significant for drilling *** the intelligent ROP prediction model based on fully connected neural networks(FNN)outperforms traditional ROP equations and machine learning algorithms,its lack of interpretability undermines its *** study proposes a novel interpretation and characterization method for the FNN ROP prediction model using the Rectified Linear Unit(ReLU)activation *** leveraging the derivative of the ReLU function,the FNN function calculation process is transformed into vector *** FNN model is linearly characterized through further simplification,enabling its interpretation and *** proposed method is applied in ROP prediction scenarios using drilling data from three vertical wells in the Tarim *** results demonstrate that the FNN ROP prediction model with ReLU as the activation function performs exceptionally *** relative activation frequency curve of hidden layer neurons aids in analyzing the overfitting of the FNN ROP model and determining drilling data *** the well sections with similar drilling data,averaging the weight parameters enables linear characterization of the FNN ROP prediction model,leading to the establishment of a corresponding linear representation ***,the quantitative analysis of each feature's influence on ROP facilitates the proposal of drilling parameter optimization schemes for the current well *** established linear characterization equation exhibits high precision,strong stability,and adaptability through the application and validation across multiple well sections.

关键词： Fully connected neural network Explainable artificial intelligence Rate of penetration ReLU active function Deep learning Machine learning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：