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Overview of in-situ oxygen production technologies for lunar resources

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 233-255页

作者： Youpeng Xu Sheng Pang liangwei Cong Guoyu Qian Dong Wang Laishi li Yusheng Wu zhi Wang College of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China CAS Key Laboratory of Green Process and Engineering National Engineering Research Center for Green Recycling of Strategic Metal ResourcesInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China

The rich resources and unique environment of the Moon make it an ideal location for human expansion and the utilization of extraterrestrial ***,crucial for supporting human life on the Moon,can be extracted from lunar regolith,which is highly rich in oxygen and contains polymetallic *** oxygen and metal extraction can be achieved using existing metallurgical ***,the ample reserves of water ice on the Moon offer another means for oxygen *** paper offers a detailed overview of the leading technologies for achieving oxygen production on the Moon,drawing from an analysis of lunar resources and environmental *** delves into the principles,processes,advantages,and drawbacks of water-ice electrolysis,two-step oxygen production from lunar regolith,and one-step oxygen production from lunar *** two-step methods involve hydrogen reduction,carbothermal reduction,and hydrometallurgy,while the one-step methods encompass fluorination/chlorination,high-temperature decomposition,molten salt electrolysis,and molten regolith electrolysis(MOE).Following a thorough comparison of raw materials,equipment,technology,and economic viability,MOE is identified as the most promising approach for future in-situ oxygen production on the *** the corrosion characteristics of molten lunar regolith at high temperatures,along with the Moon's low-gravity environment,the development of inexpensive and stable inert anodes and electrolysis devices that can easily collect oxygen is critical for promoting MOE technology on the *** review significantly contributes to our understanding of in-situ oxygen production technologies on the Moon and supports upcoming lunar exploration initiatives.

关键词： lunar resources in-situ oxygen production space metallurgy molten lunar regolith electrolysis

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Targeted migration of engrafted neural precursor cells derived from ES cells and their differentiation in A β-injuried hippocampus of rats

Targeted migration of engrafted neural precursor cells deriv...

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中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Jun TANG,Hai-Wei XU~*,Xiao-Tang FAN,zhi-Fang li,da-Bing li,li YANG,Guang-Ji ZHOU Department of Physiology,Third Military Medical University,Chongqing,400038,China

＜正＞Neural stem cells（NSCs） could be applied for neuronal regeneration and structural brain repair only when they migrate within the CNS and reach the precise regions where neuronal replacement is *** the brain was injuried, NSCs in the hippocampus and subventricular zone（SVZ） of the adult changed their migratory route and moved toward the injury *** present study,we observed the migration and differentiation of neural precursor cells（NPCs） derived from murine embryonic stem（ES） cells when transplanted into the A β-injuried hippocampus of *** between migration distance and differentiation ratio of the engrafted NPCs was also *** ES cell line MESPU35,which expressing enhanced green fluorescent protein（EGFP）,was differentiated into nestin-positive NPCs with modified serumfree methods before *** migration distance was increased about 5 times 12 weeks *** differentiation ratio to GFAP-positive cells of migratory NPCs kept rising from about 30.41±1.45%in 4 weeks to 49.25±1.23%in 16 weeks,and differentiation ratio to NF200-positive cells was increased from 16.68±0.95%in 4 weeks to 27.94±1.21%in 16 ***,the percentage of migratory GFAP-positive cells distributed at the ipsilateral of Aβplaques were increased from 60.2%to 81.3%,and the percentage of migratory NF200-positive cells localized at the ipsilateral was increased from 61.3%to 84.1%.It showed that there was a significant positive linear correlation between migration distance and the neural differentiation ratio（correlation coefficient,r=0.991）,a significant positive linear correlation between migration distance and differentiation ratio to astrocyte（correlation coefficient,r = 0.953）.Our findings suggested that engrafted NPCs migrated targetedly to the A β-injured site and differentiated into neurons and astrocyte.

关键词： Embryonic stem cells β-amyloid peptide Cell transplantation Differentiation Migration Rat

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Synergistic effect of bonding heterogeneity and phonon localization in introducing excellent thermoelectric properties in layered heteroanionic NdZnSbO material

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Journal of Energy Chemistry 2025年第1期100卷 259-272页

作者： da Wan Shuwei Tang Shulin Bai Xiaodong li Peng Ai Wanrong Guo Tuo Zheng College of Materials Science and Engineering Liaoning Technical University Faculty of Chemistry Northeast Normal University

Layered rare-earth metal oxides, harnessing the dual properties of oxides and two-dimensional layered materials, exhibit remarkable thermal stability and quantum confinement effects. Therefore, this work adopts the first-principles calculation combined with the Boltzmann transport theory to predict the thermoelectric properties of NdZnSbO compound. The coexistence of weak interlayer van der Waals interactions, robust intralayer ionic bonding, and partial covalent bonding leads to remarkable bonding heterogeneity, which engenders pronounced phonon scattering and imposes constraints on thermal transport along the out-of-plane direction. The weakened chemical bonds induced by the antibonding states, together with the rattling-like behavior of the Zn atom, culminate in the profound anharmonicity in the layered NdZnSbO compound. The weakening bond and heavy element contribute to the softness of phonon modes, which significantly diminishes the phonon group velocity. The redistribution-dominated four-phonon scattering process spans a large optical gap, which effectively reduces the lattice thermal conductivity. The NdZnSbO compound exhibits direct semiconductor characteristic with a bandgap of 0.73 e V by adopting the Heyd-Scuseria-Ernzerhof(HSE06) functional in combination with spin–orbit coupling(SOC) effect. The multi-valley feature of NdZnSbO compound augur favorably for band degeneracy, thus amplifying the power factor. Consequently, an optimal figure-of-merit(ZT) of 3.40 at 900 K is achieved for the n-type NdZnSbO compound. The present study delves deeply insights into the origins for the low thermal conductivity of NdZnSbO compound and proposes an optimization scheme to enhance overall thermoelectric performance.

关键词： Bond strength (chemical)

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Progress in research into the mechanism of Radix salviae miltiorrhizae in treatment of acute pancreatitis

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Hepatobiliary & Pancreatic Diseases International 2006年第4期5卷 501-504页

作者： Xi-Ping Zhang, zhi-Jun li and da-Ren liu Department of General Surgery, Hangzhou First People’s Hospital, Hangzhou 310006, China , Zhejiang University of Traditional Chinese Medine, Hangzhou 310053, China Department of General Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China Department of General Surgery Hangzhou First People's Hospital Hangzhou 310006 China. zxp99688@***

BACKGROUND: Acute pancreatitis (AP) is a common acute abdomen with high mortality, multiple complications and complicated causes. There is no effective therapy for AP. Radix salviae miltiorrhizae (danshen), a traditional herbal medicine, has a low price and a wide range of clinical applications. It is effective to promote blood flow, eliminate stagnancy, and relieve pain. It is also found to be effective in treating AP. We reviewed the progress in research into the mechanism of Radix salviae miltiorrhizae in treatment of AP. daTA SOURCES: An english-language literature search was conducted using MEDliNE (1988-2005) on Radix salviae miltiorrhizae (danshen) and acute pancreatitis. RESULTS: The mechanisms of danshen in the treatment of AP include improvement of microcirculatory disturbances; elimination of oxygen free radicals; modulation of the metabolism of lipid inflammatory mediator; and blocking of calcium inflow and prevention of calcium ***: danshen can effectively reduce the mortality and complications of AP.

关键词： Radix salviae miltiorrhizae (danshen) acute pancreatitis mechanism

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Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen li Hui Ye Xue-zhi Zhang Jian-Xiang liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

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A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： zhi li Yang Wei Kang Zhou Xin Huang Xing Zhou Jie Xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （lic *** three-sodium storage mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

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急性生理与慢性健康状况评分Ⅱ在老年高渗性高血糖状态患者中的应用

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中华老年医学杂志 2009年第4期28卷 298-300页

作者：支力大张国强张坚 Xiaoqiang Mingyang li 闫圣涛郭诗东北京中日友好医院急诊科 100029 Lawrence S. Bloomberg Faculty ot Nursing University of Toronto

目的探讨急性生理与慢性健康状况评分（APACHE）Ⅱ对糖尿病高渗性高血糖状态患者病情评价和治疗预后的价值。方法2003年1月至2008年5月．在本院急诊抢救室治疗的糖尿病高渗性高血糖状态患者在入院当天进行治疗前APACHEⅡ评分，根据患者... 详细信息

目的探讨急性生理与慢性健康状况评分（APACHE）Ⅱ对糖尿病高渗性高血糖状态患者病情评价和治疗预后的价值。方法2003年1月至2008年5月．在本院急诊抢救室治疗的糖尿病高渗性高血糖状态患者在入院当天进行治疗前APACHEⅡ评分，根据患者预后分为死亡组和存活组，对两组APACHEⅡ评分进行比较。应用Logistic同归分析评价死亡的危险因素。结果40例患者入选，死亡10例，存活30例，病死率为25／00。治疗前两组患者血糖、血钠、血渗透压、血肌酐和血红蛋白差异无统计学意义（t=-1．50～1．53，P〉0．05）。入院当天治疗前死亡组APACHEⅡ评分分值明显高于存活组，分别为（30．1±5．4）分和（22．9±3．9）分（Z=-4．08．P〈0．01）；Logistic回归分析显示，入院当天治疗前APACHEⅡ分值是死亡独立危险因素．年龄、性别、血糖、有效血渗透压、血肌酐和血红蛋白不是死亡危险因素。结论APACHEⅡ评分有助于评价糖尿病高渗性高血糖状态患者的病情和预后。

关键词：急性病生理学和长期健康评价糖尿病高血糖高渗性非酮性昏迷

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三方不经意多项式求值协议

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计算机工程与设计 2016年第11期37卷 2934-2938页

作者：杨博为孙达志李晓红华东师范大学上海市高可信计算重点实验室上海200241 天津大学计算机科学与技术学院天津300072 中国科学院信息工程研究所信息安全国家重点实验室北京100093

针对多方计算中的隐私保护问题,提出一种三方不经意多项式求值协议。协议拥有3个参与者,分别为一个发送者和两个接收者,发送者拥有一个二元多项式P(x,y),两个接收者分别拥有α和β。该协议通过使用Diffie-Hellman密钥交换协议和任意一... 详细信息

针对多方计算中的隐私保护问题,提出一种三方不经意多项式求值协议。协议拥有3个参与者,分别为一个发送者和两个接收者,发送者拥有一个二元多项式P(x,y),两个接收者分别拥有α和β。该协议通过使用Diffie-Hellman密钥交换协议和任意一种安全的不经意传输协议来实现,完成如下目标:接收者得到P(α,β)的值,但无法得到关于多项式P的任何信息,发送者无法得到关于α和β的任何信息。理论分析结果表明了协议的正确性和对发送者、接收者的安全性,给出了该协议在两方Hamming距离安全计算中的应用,拓展了不经意传输协议的使用范围,为安全多方计算的实现提供了一种新途径。

关键词：安全多方计算不经意传输不经意多项式求值隐私保护密码协议

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乌司他丁与1，6二磷酸果糖对脑缺血-再灌注谷胱甘肽过氧化物酶和丙二醛影响

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中华急诊医学杂志 2007年第6期16卷 619-621页

作者：张坚闫圣涛郭诗东支力大中日友好医院急诊科北京100029

目的研究乌司他丁(UTI)与1,6二磷酸果糖(FDP)对脑缺血-再灌注损伤保护作用,探讨乌司他丁(UTI)联合FDP对脑缺血.再灌注损伤的保护机制。方法纯种白兔随机分为四组(n=6):对照组、UTI保护组、FDP保护组及UTI+FDP保护组。四管闭塞法制成兔... 详细信息

目的研究乌司他丁(UTI)与1,6二磷酸果糖(FDP)对脑缺血-再灌注损伤保护作用,探讨乌司他丁(UTI)联合FDP对脑缺血.再灌注损伤的保护机制。方法纯种白兔随机分为四组(n=6):对照组、UTI保护组、FDP保护组及UTI+FDP保护组。四管闭塞法制成兔全脑缺血-再灌注损伤模型。分别缺血再灌注即刻给予生理盐水、UTI(10μ/kg)、FDP(200 mg/kg)及UTI+ FDP。再灌注后30 min、3 h、6 h静脉血测丙二醛(Mda)和谷光甘肽过氧化物酶(GSH-Px)。结果Mda和GSH-Px值显示对照组与UTI、FDP、及UTI+FDP组比较各组P0.05,3 h后P<0.01。结论UTI联合FDP对脑缺血-再灌注损伤保护作用与单独应用差异明显。表明UTI及FDP对脑缺血-再灌注损伤有保护作用,二者合用较单独应用效果更好。

关键词：缺血-再灌注损伤乌司他丁 1,6二磷酸果糖

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Induced pluripotent stem cell-related approaches to generate dopaminergic neurons for Parkinson's disease

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Neural Regeneration Research 2025年第11期20卷 3193-3206页

作者： ling-Xiao Yi Hui Ren Woon Genevieve Saw li Zeng Eng King Tan zhi Dong Zhou National Neuroscience Institute Singapore Nanyang Technology University Singapore Department of Neurology Singapore General HospitalSingapore Signature Research Program in Neuroscience and Behavioral Disorders Duke-NUS Medical SchoolSingapore

The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative *** the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and *** induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease *** current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem *** benefits of induced pluripotent stem cell-based research are *** dopaminergic neuron differentiation protocols from induced pluripotent stem cells are *** emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are ***,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.

关键词： dopaminergic neurons induced pluripotent stem cells Parkinson's disease stem cell approaches

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