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SalenZn-bridged D-π-A Dyes For Dye-Sensitized Solar Cells

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Chinese Journal of Chemistry 2014年第6期32卷 513-520页

作者： Yongjian Jia Faliang Gou Ran Fang Huanwang Jing zhenping zhu State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering Lanzhou UniversityLanzhouGansu 730000China State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesTaiyuanShanxi 030001China

A series of SalenZn based dyes with triphenylamine derivatives as the donor,benzoic acid as the acceptor,and coplanar Salen complexes as the spacer have been designed and synthesized for dye-sensitized solar *** ab-sorption,electrochemical,and photovoltaic properties for all sensitizers have been systematically *** the tail length of the alkyl substituents is increased from C-0 to C-8 on the donor part,the efficiency of its DSSC augments *** is found that the incorporation of bis-carboxyl groups instead of the single carboxyl group as anchoring groups induces a remarkable enhancement of the electron injection efficiency from the excited dyes to the TiO_(2)semiconductor and generates higher electron density and voltage.

关键词： dye-sensitized solar cells SalenZn complexes salicylic acid anchoring group

Targeted cancer therapies based on antibodies directed against epidermal growth factor receptor:status and perspectives

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Acta Pharmacologica Sinica 2007年第9期28卷 1476-1493页

作者： zhenping zhu Im Clone Systems Incorporated,New York,NY 10014,USA ImClone Systems Incorporated New York USA

Compelling experimental and clinical evidence suggests that epidermal growthfactor receptor (EGFR) plays an important role in the pathogenesis of a variety ofhuman cancers;thus,providing a strong rationale for the development of receptorantagonists as effective and specific therapeutic strategies for the treatment ofEGFR-expressing *** antibodies (mAb),owing to their highspecificity towards a given target,represent a unique class of novel cancertherapeutics.A number of anti-EGFR mAb are currently being developed in ourclinic,including two that have been approved by the United States Food andDrug Administration for the treatment of refractory metastatic colorectal cancer(mCRC) and squamous cell carcinomas of the head and neck (SCCHN).Cetuximab(Erbitux,IMC-C225),an IgG1 mAb,has demonstrated significant antitumor activity,both as a single agent and in combination with chemotherapeutics and radiation,in patients with refractory mCRC and SCCHN,***(Vectibix),an IgG2 mAb,has been approved as a single agent for the treatment ofpatients with refractory *** mAb,via blocking ligand/receptorinteractions,exert their biological activity via multiple mechanisms,includinginhibition of cell cycle progression,potentiation of cell apoptosis,inhibition ofDNA repair,inhibition of angiogenesis,tumor cell invasion and metastasis and,potentially,induction of immunological effector ***-EGFR anti-bodies have demonstrated good safety profiles and potent anticancer activity inour clinic and may prove to be efficacious agents in the treatment of a variety ofhuman malignancies.

关键词： wear particles osteolysis aseptic loosening doxycycline

Efficacy of anti-CD20 chimeric Fab' fragment on proliferation of B lymphoma cells

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Chinese Science Bulletin 2001年第14期46卷 1182-1186页

作者： LAI Zengzu XIONG Dongsheng FAN Dongmei XU Yuanfu LIU Hanzhi PENG Hui zhu zhenping YANG Chunzheng National Laboratory of Experimental Hematology Institute of Hematol-ogyChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China

The variable domain of heavy chain (VH) and light chain (VL) genes of anti-CD20 monoclonal antibody HL47 were cloned from anti-CD20 ScFv expression vector pCANBTEcd20 by PCR and ligated into vector pYZF to construct chimeric anti-CD20 Fab’ fragment expression vector pTZFcd20. Chimeric anti-CD20 Fab’ fragment was expressed in E. coli 16C9 and purified by protein G affinity chromatography. Competitive inhibition assay showed that anti-CD20 Fab’ fragment inhibited binding of HI47 to CD20 on the surface of Daudi cells. Results from MTT assay indicated that chimeric anti-CD20 Fab’fragment inhibited the proliferation of Daudi cells, IC50=69 ug/mL. Affinity of chimeric anti-CD20 Fab’ fragment was determined, Ka was about 8.9×108 (mol/L)-1.

关键词： monoclonal antibody chimeric Fab’ B lymphoma CD20.

Mechanism study and molecular design in controlled/“living” radical polymerization

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Science China Chemistry 2010年第8期53卷 1605-1619页

作者： TU YingFeng,CHENG zhenping,ZHANG ZhengBiao,zhu Jian,ZHANG Wei,ZHOU NianChen,NI PeiHong & zhu XiuLin College of Chemistry,Chemical Engineering and Materials Science,Soochow University,Suzhou 215123,China College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou China

This tutorial review summarizes recent progress in the research field of controlled/"living" radical polymerization (CLRP) from Soochow *** present paper gives a broad overview of the mechanism study and molecular design in *** mechanism study in CLRP aided by microwave,initiated by γ-radiation at low temperature,mediated by iron,in reversible addition-fragmentation chain transfer (RAFT) polymerization and the mechanism transfer between different CLRP processes are reviewed and *** molecular design in CLRP,especially in RAFT polymerization for mechanism study,and in achieving tailor-made functional polymers is studied and discussed in the later part.

关键词： controlled/"living" radical polymerization atom transfer radical polymerization reversible addition-fragmentation chain transfer polymerization molecule design mechanism study

Controlled synthesis and luminance properties of lanthanide-doped β-NaYF_4 microcrystals

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Journal of Rare Earths 2015年第4期33卷 339-345页

作者：王军梅李克训赵彦保朱珍平 Key Laboratory for Special Functional Materials Henan University State Kay Laboratory of Coal Conversion Institute of Coal Chemistry Chinese Academy of Sciences University of Chinese Academy of Sciences The Electromagnetic Protection Technology Key Laboratory of Shanxi of NO.33 Institute of China Electronic Technology Group Corporation

Hexagonal yb3＋,Er3＋-doped NaYF4 crystals with different morphologies were synthesized by a facile hydrothermal method at 140-200 ℃. Their shape and size could be controlled by varying hydrothermal temperature, time and doping effect of Ce3＋ ions. Interestingly, the products displayed hexagonal sheet, plate, crown-like prism to tube changes in the temperature range from 140 to 200 ℃. A combination of ＂diffusion-controlled growth＂ and ＂selective adsorption＂ was proposed to understand the formation of the NaYF4 crystals with well-defined shapes. NaYF4：yb3＋/Er3＋ crystals exhibited shape-dependent up-conversion （UC） luminescence under excitation of 980 nm, and their luminescence property could be tuned by doping Ce3＋ ions.

关键词： nanostructures inorganic compounds chemical synthesis optical properties rare earths

大采高大断面碎裂煤巷围岩稳定性控制对策研究

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矿业研究与开发 2018年第11期38卷 46-50页

作者：朱振平长治三元中能煤业有限公司山西长治市046600

针对大采高大断面碎裂回采巷道受多次采动影响进而诱发围岩碎裂变形失稳的难题,以长治三元中能煤业2302大采高工作面回风平巷为研究对象,综合运用现场监测、钻孔窥视、数值模拟及工程实践等多种研究方法对后续试验段巷道围岩变形破坏机... 详细信息

针对大采高大断面碎裂回采巷道受多次采动影响进而诱发围岩碎裂变形失稳的难题,以长治三元中能煤业2302大采高工作面回风平巷为研究对象,综合运用现场监测、钻孔窥视、数值模拟及工程实践等多种研究方法对后续试验段巷道围岩变形破坏机理与强化控制技术进行了系统研究,提出以"高强全断面锚网+高强加长锚杆+高预应力强力锚索"为基础的围岩强化控制方案,并成功应用于现场工程实践,确保了大断面碎裂煤巷围岩在采掘全过程中的安全稳定性。

关键词：围岩稳定性大采高大断面数值模拟强化控制

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治疗性抗体药物发展现状及展望

科学 2011年第1期63卷 12-16页

作者：朱祯平美国Kadmon制药公司纽约10016美国

抗体是机体对抗原刺激发生反应，由浆细胞产生的一种免疫球蛋白，它能特异性地识别相应的抗原物质并与之反应。抗体是体内最奇妙的分子，有巨大的多样性，任何被人体免疫系统视为“异己”的外源性物质，如细菌、病毒或毒素等，都能引起... 详细信息

抗体是机体对抗原刺激发生反应，由浆细胞产生的一种免疫球蛋白，它能特异性地识别相应的抗原物质并与之反应。抗体是体内最奇妙的分子，有巨大的多样性，任何被人体免疫系统视为“异己”的外源性物质，如细菌、病毒或毒素等，都能引起机体产生抗体，从而发挥预防和治疗疾病的作用。

关键词：抗体受体基因工程药物

Selectively modifying carbon nanotubes with carboxyl / hydroxyl groups and their catalytic activity

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Selectively modifying carbon nanotubes with carboxyl / hydro...

New concepts for the controllable construction of carbon nanostructures and their catalytic functions in new energy processes

第十四届全国催化学术会议

作者： Li Wang Jianghong Zhao Shuli Bai Chang Song Souai Feng zhenping zhu State Key Laboratory of Coal Conversion Institute of Coal Chemistry CAS

＜正＞*** The unique one-dimensional tubular structure and accessible surface make carbon nanotubes（CNTs）an intriguing candidate of catalyst ***,their surface properties can be altered by selectively modifying with different functional *** was reported that the oxygen-containing functional groups brought about increase of the corresponding catalyst dispersion and loading of active phase on the surface of CNTs,thus promoted its catalytic ***,it is difficult to get clear understanding about the

关键词： carbon nanotubes selectively modifying catalytic

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New concepts for the controllable construction of carbon nan...