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Acta Mechanica Sinica 2014年第3期30卷 403-409页

作者： Run-Tao Zhan zhao-xia li Lei Wang Department of Engineering Mechanics Southeast UniversityJiangsu Key Laboratory of Engineering Mechanics School of Civil Engineering Southeast University

Fractional differential constitutive relationships are introduced to depict the history of dynamic stress inten- sity factors （DSIFs） for a semi-infinite crack in infinite viscoelastic material subjected to anti-plane shear impact load. The basic equations which govern the anti-plane deformation behavior are converted to a fractional wave-like equation. By utilizing Laplace and Fourier integral transforms, the fractional wave-like equation is cast into an ordinary differential equation （ODE）. The unknown function in the solution of ODE is obtained by applying Fourier transform directly to the boundary conditions of fractional wave-like equation in Laplace domain instead of solving dual integral equations. Analytical solutions of DSIFs in Laplace domain are derived by Wiener-Hopf technique and the numerical solutions of DSIFs in time domain are obtained by Talbot algorithm. The effects of four parameters α, β, b1, b2 of the fractional dif- ferential constitutive model on DSIFs are discussed. The numerical results show that the present fractional differential constitutive model can well describe the behavior of DSIFs of anti-plane fracture in viscoelastic materials, and the model is also compatible with solutions of DSIFs of anti-plane fracture in elastic materials.

关键词： Dynamic fracture Stress intensity factors Fractional differentiation - Anti-plane fracture Viscoelasticmaterial Wiener-Hopf

Gene Sequence, Soluble Expression and Homologous Comparison of a D-Hydantoinase fromPseudomonas putida YZ-26

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Chemical Research in Chinese Universities 2005年第5期21卷 552-557页

作者： SHI Ya-wei zhao li-xia NIU li-xi FENG xia YUAN Jing-ming Key Laboratory for Chemical Biology and Molecular Engineering of Ministry of Education Institute of Biotechnology Shanxi University Taiyuan 030006 P. R. China

A 1440bp open-reading frame encoding D-hydantoinase from Pseudomonas putida YZ-26 was cloned and sequenced（ GenBank AY387829）. The DNA fragment was inserted into Nde and BamHI sites of vector pET-3a, yielding a recombinant plasmid, pET-HDT. After being transferred into the host strain, the artificial strain, pET-HDT/ E. coli BL21 can express the D-hydantoinase as the soluble form in the Lura-Bertani medium without addition of any inducers. The activity of the enzyme toward substrate DL-hydantoin can reach 3000-4000 IU per cells from one-liter bacterial culture incubated at 30 ℃ for 10-12 h. By the comparison of amino acid sequence homology, hydrophobic residues analysis and secondary structure prediction, it was found that D-hydantoinase reported herein is quite similar to that from Pseudomonas putdia CCRC12857, and alike to that from Pseudomonas putdia DSM84 or other bacteria. A rapid and efficient purification procedure of the enzyme was performed by a three-step procedure： ammonium sulfate fractionation, phenyl Sepharose hydrophobic interaction chromatography and Sephacryl S-200 gel filtration. The molecular mass of the monomeric enzyme is 52042 Da as determined by MALDI-TOF mass spectrometry.

关键词： D-Hydantoinase Gene sequence Soluble expression Homologous comparison Purification Mass spectrum

Study on superoxide and hydroxyl radicals generated in indirect electrochemical oxidation by chemiluminescence and UV-Visible spectra

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Journal of Environmental Sciences 2008年第8期20卷 1006-1011页

作者： ZHANG, Bo-Tao zhao, li-xia liN, Jin-Ming State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China Department of Chemistry Tsinghua University Beijing 100084 China

The generation and transformation of radicals on the cathode of indirect electrochemical oxidation were studied by chemilumines- cence(CL)and UV-Visible spectra in the reactor with a salt bridge that connected the separated *** CL intensity of 4×10^(-9)mol/L luminol on the cathode with bubbling oxygen was about seven times that of the intensity without it,which was because of the generation of reactive oxygen species(ROS).The existence of ROS,especially the generation of the superoxide radical,coul...

关键词： chemiluminescence(CL) UV-Visible radical indirect electrochemical oxidation

Chromosomal imbalances revealed in primary rhabdomyosarcomas by comparative genomic hybridization

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Chinese Medical Journal 2009年第11期122卷 1277-1282页

作者： li Qiao-xin liU Chun-xia CHUN Cai-pu QI Yan CHANG Bin li Xin-xia CHEN Yun-zhao NONG Wei-xia li Hong-an li Feng Department of Pathology Key Laboratory of Xinjiang Endemic & Ethnic Disease of Ministry of Education Shihezi University School of Medicine Shihezi Xinjiang 832002 China

Background Previous cytogenetic studies revealed rhabdomyosarcoma. We profiled chromosomal imbalances aberrations varied among the three subtypes of n the different subtypes and investigated the relationships between clinical parameters and genomic aberrations. Methods Comparative genomic hybridization was used to investigate genomic imbalances in 25 cases of primary rhabdomyosarcomas and two rhabdomyosarcoma cell lines. Specimens were reviewed to determine histological type, pathological grading and clinical staging. Results Changes involving one or more regions of the genome were seen in all rhabdomyosarcomal patients. For rhabdomyosarcoma, DNA sequence gains were most frequently （〉30%） seen in chromosomes 2p, 12q, 6p, 9q, 10q, lp, 2q, 6q, 8q, 15q and 18q; losses from 3p, 11p and 6p. In aggressive alveolar rhabdomyosarcoma, frequent gains were seen on chromosomes 12q, 2p, 6p, 2q, 4q, 10q and 15q; losses from 3p, 6p, lq and 5q. For embryonic rhabdomyosarcoma, frequent gains were on 7p, 9q, 2p, 18q, lp and 8q; losses only from 11p. Frequently gained chromosome arms of translocation associated with rhabdomyosarcoma were 12q, 2, 6, 10q, 4q and 15q; losses from 3p, 6p and 5q. The frequently gained chromosome arms of nontranslocation associated with rhabdomyosarcoma were 2p, 9q and 18q, while 11p and 14q were the frequently lost chromosome arms. Gains on chromosome 12q were significantly correlated with translocation type. Gains on chromosome 9q were significantly correlated with clinical staging. Conclusions Gains on chromosomes 2p, 12q, 6p, 9q, 10q, lp, 2q, 6q, 8q, 15q and 18q and losses on chromosomes 3p, 11p and 6p may be related to rhabdomyosarcomal carcinogenesis. Furthermore, gains on chromosome 12q may be correlated with translocation and gains on chromosome 9q with the early stages of rhabdomyosarcoma.

关键词： rhabdomyosarcoma fusion gene comparative genomic hybridization

Pre-treatment with puerarin affects pharmacokinetics of warfarin, but not clopidogrel, in experimental rats

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Chinese Journal of Natural Medicines 2015年第4期13卷 257-263页

作者： liU An-Chang zhao li-xia YU Shu-Wen LOU Hong-xiang Qilu hospital of Shandong University Jinan Central Hospital Affiliated to Shandong University School of Pharmaceutical Sciences Shandong University

The present study was designed to determine the effects of puerarin pre-treatment on the pharmacokinetics of the oral anticoagulant agent warfarin and the antiplatelet agent clopidogrel in rats. In the treatment group, rats was gavaged with warfarin or clopidogrel after repeated treatment with puerarin at intraperitoneal doses of 20, 60, or 200 mg·kg-1 for 7 days, while rats in the control group were administrated only with the same dose warfarin or clopidogrel. Plasma samples were obtained at the prescribed times and analyzed by liquid chromatography tandem mass spectrometry(LC-MS/MS). The results showed that rats treated with puerarin at all the test doses of 20, 60 and 200 mg·kg-1 were found to affect the pharmacokinetics of warfarin, but not clopidogrel, suggesting a potential herb-drug interaction between puerarin and warfarin.

关键词： Puerarin Warfarin Clopidogrel Pharmacokinetics Drug interaction

A Case Study on xiamen-TSA(1998)in China

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Journal of Systems Science and Systems Engineering 2001年第4期13卷 443-449页

作者： zhao li-xia Dept. of Planning & Statistics, xiamen University, xiamen 36l005, China Dept. of Planning & Statistics Xiamen University Xiamen 361005 China

Tourism Satellite Account (TSA) is the newest method for measuring the impact of tourism on economy in the wor1d. There has been globally a big trend of development of TSAs after it was approved as a internationa1 standard by United Nations Statistica1 Commission (UNSC) in March of 2000. This research is a first pilot exercise of TSA method in China. The result of the research has drawn much attention from the tourism administrations and statistics offices at national level and the 1ocal levels.

关键词： tourism satellite account j tourism statistics the tourism's impact on economy

YANJI CITY ORIENTATION AND INDUSTRYDEVELOPMENT TOWARDS 21ST CENTURY

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Chinese Geographical Science 2001年第1期11卷 70-75页

作者： ZHANG Ping-yu, MA Yan-ji, zhao Yan-xia, PAN li-li (Changchun Institute of Geography, the Chinese Academy of Sciences, Changchun 130021, P. R. China) Changchun Institute of Geography the Chinese Academy of Sciences Changchun P. R. China

Yanji is the biggest China Korean inhabited city. Based on a newly finished research project, this paper discusses strategic problems about Yanji towards 21st century. The general point of the authors is that at the beginning of new century, Yanji will play a more important role in Tumen River Delta development, regional economy cooperation in Korea Peninsula as well as Northeast Asia, and it will develop to be an important central city in this area. This paper puts forwards Yanji City’s developing goal, urban nature, and urban size, probes its regional orientation, and further probes how to establish The Yanji Urban Economy Cooperation Zone. The authors think that Yanji should depend on its intellect resources and other characteristic resources. Industry development need to pay much attention to modern agriculture, tertiary industry (especially commerce, trade and tourism) and dominant industries, and high-tech industry must give a special care, in order to establish a light industrial structure.

关键词： Yanji China Korean city orientation industry development

Development of High Deformation X70 Pipeline Steel Plates in NISCO

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Journal of Iron and Steel Research International 2011年第S1期18卷 915-919页

作者： liU zhao-xia,li xiao-ling,CHEN Yuan-shu,SONG Shi-jia (Technology and Quality Department,Jiangsu Nanjing Iron and Steel Cooperation,Nanjing 210035,Jiangsu,China) Jiangsu Nanjing Iron & Steel Cooperat Technol & Qual Dept Nanjing 210035 Jiangsu Peoples R China

A series of trial tests for high deformation (HD) X70 pipeline steel plates were performed in NISCO,and the technical routes as thermal mechanical controlled rolling process (TMCP),TMCP + Quenching (Q) and TMCP +Q & tempering (T) were studied systematically through the plate shape quality,properties and microstructure *** results show that problems as plate shape and inhomogeneous microstructures are for finish rolling at low temperature and high cooling rate after the rolling by the route of *** the route of TMCP+Q,the yield strength (YS) of the trial steels is not *** the route of TMCP+QT,the YS is enhanced,as well as good toughness and plasticity due to the martensite decomposition at low temperature tempering process,and 4 sheets of HD X70 pipeline steel plates by the route TMCP+QT with superior plate shape quality,microstructure and comprehensive properties were successfully developed in NISCO.

关键词： high deformation pipeline steel microstructure TMCP quenching tempering

Enhanced mechanical stability and corrosion resistance ofsuperhydrophobic coating reinforced with inorganic binder

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Journal of Central South University 2024年第10期31卷 3502-3516页

作者： zhao li-xia li Hong-yan ZHOU Kun liU Hai-xing WANG Jian ZHANG Bin-bin College of Chemistry and Molecular Engineering Qingdao University of Science and TechnologyQingdao 266042China Key Laboratory of Advanced Marine Materials Key Laboratory of Marine Environmental Corrosion and Bio-foulingInstitute of OceanologyChinese Academy of SciencesQingdao 266071China College of Marine Science and Biological Engineering Qingdao University of Science and TechnologyQingdao 266042China Pipe China Tianjin LNG Co. Ltd.Tianjin 300452China Department of Materials Science and Engineering School of Materials and Chemical TechnologyTokyo Institute of TechnologyTokyo 152-8552Japan

The development of superhydrophobic materials has demonstrated significant potential in the realm ofcorrosion protection for aluminum alloy(Al alloy)***,the limited mechanical stability ofsuperhydrophobic surfaces has impeded the rapid advancement in this *** this research,we synthesized analuminum phosphate(AP)inorganic binder and combined it with hydrophobic fumed SiO_(2)(HF-SiO_(2))nanoparticles andpolydimethylsiloxane(PDMS)to develop a HF-SiO_(2)@PDMS@AP superhydrophobic composite coating with improvedmechanical stability on Al alloy substrates using a simple spray-coating *** findings indicate that the additionof the AP inorganic binder significantly enhanced the coating’s resistance to abrasion,maintaining its superhydrophobicproperties and micro-nano hierarchical structure even after being subjected to a sandpaper abrasion distance of 2000 *** impedance spectroscopy(EIS)testing showed that the low-frequency modulus(|Z|0.01Hz)of theHF-SiO_(2)@PDMS@AP superhydrophobic coating increased by four orders of magnitude compared to the initial Al alloysubstrate,resulting in a substantial improvement in corrosion protection *** impressive corrosion resistanceand mechanical stability exhibited by this coating have the potential to greatly expand the practical applications of suchmaterials for surface functional protection in marine and industrial environments.

关键词： superhydrophobicity anti-corrosion stability self-cleaning

泪液及血清白介素及微量元素与白内障的关系研究

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国际眼科杂志 2016年第2期16卷 281-283页

作者：李赵霞中国上海市浦东新区人民医院眼科 201299

目的:研究及分析泪液及血清白介素及微量元素与白内障的关系,为白内障的防控、诊断及治疗提供依据。方法:选取2014-06/2015-04于本院进行治疗的67例白内障患者为观察组,并从于本院体检者中选取67例同龄健康人为对照组,然后将两组的泪液... 详细信息

目的:研究及分析泪液及血清白介素及微量元素与白内障的关系,为白内障的防控、诊断及治疗提供依据。方法:选取2014-06/2015-04于本院进行治疗的67例白内障患者为观察组,并从于本院体检者中选取67例同龄健康人为对照组,然后将两组的泪液及血清白介素、微量元素进行检测及比较,并比较不同发病时间及分期白内障患者的上述检测指标,并采用logistic法分析泪液及血清检测指标与白内障的关系。结果:观察组的泪液及血清白介素均高于对照组,而微量元素则低于对照组,且不同疾病分期白内障患者的检测指标也存在明显差异(均P0.05),经logistic法分析泪液及血清检测指标与白内障有密切的关系。结论:白内障患者的泪液及血清白介素及微量元素呈现异常的状态,并且不同疾病分期患者的差异也较为突出,检测指标与疾病的关系密切。

关键词：泪液血清白介素微量元素白内障