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Chinese Science Bulletin 2008年第21期53卷 3294-3300页

作者： zhao Zhe hao JiMing li JunHua WU Shan Department of Environmental Science and Engineering Tsinghua University Beijing 100084 China

Ozone(O3) and secondary organic aerosol(SOA) are considered to be the most serious secondary air pollutants of concern in most metropolitan areas,as well as for *** this study,O3 and SOA for-mation potential of α-pinene,the most abundant biogenic VOCs,is investigated at Tsinghua Indoor Chamber *** experiments were conducted under atmospheric relevant HCs/NOx ratios in both presence and absence of ammonia sulfate seed aerosol.A Scanning Mobility Particle Sizer system(3936,TSI) and a Condensation Particle Counter(3010,TSI) were used to study the SOA formation and a gas chromatograph(GC) equipped with a DB-5 column and a flame ionization detector(FID) was used to measure α-pinene *** results show that the presence of ammonia sulfate seed aerosol did not change the formation trend of O3,but significantly contribute to SOA formation.A strong linear relationship(r2 = 0.90) between SOA yield enhancement(△Y*) and surface concentration of seed aerosol(PMi,s)has been found,denoting that the PMi,s is the control factor for SOA yield *** the possible reason for the enhancement is acid-catalyzed heterogeneous reactions.

关键词：种子微粒物气溶胶照射 a-蒎烯-NOx-H2O 化学

Study on the inclusion interaction of methylated-β-cyclodextrins with albendazole by spectrofluorimetry and its application

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Chinese Chemical Letters 2008年第8期19卷 951-954页

作者： Guo Yan zhao hao Wu Sheng li Dong li Ming Du Analytical and Testing Center Shanxi Normal University Linfen 041004 China

The inclusion interaction between three types of methylated-β-cyclodextrins （Me-β-CDs） and albendazole （ABZ） was studied by spectrofluorimetry. The result showed that Me-β-CDs reacted with ABZ to form an inclusion complex, 1： 1 stoichiometry for Me- β-CDs-ABZ complex was established and its association constant have been determined from fluorescence data by Benesi- Hildebrand＇s method （double reciprocal plots）. It was noted that 2,6-DM-β-CD exhibited stronger binding ability than other Me-β- CDs. Based on the significant enhancement of fluorescence intensity of inclusion complex, a simple and highly sensitive fluorimetric method is proposed for the determination of ABZ in the presence of 2,6-DM-β-CD. The proposed method was successfully applied to the determination of ABZ in tablets and human urine.

关键词： Methylated-β-cyclodextrins Albendazole Spectrofluorimetry

Preparing UO_2 kernels by gelcasting

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Nuclear Science and Techniques 2009年第2期20卷 124-128页

作者： GUO Wenli liANG Tongxiang zhao Xingyu hao Shaochang li Chengliang Institute of Nuclear and New Energy Technology Tsinghua University Beijing 100084 China

A process named gel-casting has been developed for the production of dense UO2 kernels for the high-temperature gas-cooled *** with the sol-gel process,the green microspheres can be got by dispersing the U3O8 slurry in gelcasting process,which means that gelcasting is a more facilitative process with less waste in fabricating UO2 *** UO2 kernels with the size of 500 μm,O/U≤2.01,density of 10.70 g·cm-3 were obtained by gel-casting process followed by heat treatment.

关键词：凝胶注模成型内核高温气冷实验堆铀成型过程溶胶凝胶法 U3O8 高密度

A lexicalized second-order-HMM for ambiguity resolution in Chinese segmentation and POS tagging

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High Technology Letters 2005年第4期11卷 346-350页

作者：陈鄞 Yang Muyun zhao Tiejun Yu hao li Sheng The Machine Translation Laboratory School of Computer Science and Engineering Harbin Institute of Technology Harbin 150001 P.R. China

Hidden Markov Model（HMM） is a main solution to ambiguities in Chinese segmentation anti POS （part-of-speech） tagging. While most previous works tot HMM-based Chinese segmentation anti POS tagging eonsult POS informatiou in contexts, they do not utilize lexieal information which is crucial for resoMng certain morphologieal ambiguity. This paper proposes a method which incorporates lexieal information and wider context information into HMM. Model induction anti related smoothing technique are presented in detail. Experiments indicate that this technique improves the segmentation and tagging accuracy by nearly 1%.

关键词： hidden Markov model chinese segmentation part-of-speech tagging

Establishment and Optimization of the Regeneration System of Mature Embryos of Maize (Zea mays L.)

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Agricultural Sciences in China 2008年第9期7卷 1046-1051页

作者： zhao Cheng-hao ZHANG li-jun GE Chao HU Kai College of Biotechnology Shenyang Agricultural University Shenyang 110161 P.R.China

A reliable system was developed for regeneration from mature embryos derived from callus of four maize inbred lines （liao 7980, Dan 9818, Dan 340, and Dan 5026）. The protocol was mainly based on a series of experiments involving the composition of culture medium. We found that 9 pM 2,4-dichlorophenoxyacetic acid in MS medium was optimum for the induction of callus. The induction frequency of primary calli was over 85% for four inbred lines tested. The addition of L- proline （12 mM） in subculture medium significantly promoted the formation of embryogenic callus but it did not significantly enhance growth rate of callus. Efficient shoot regeneration was obtained on regeneration medium containing 2.22 μM 6- benzylaminopurine in combinations with 4.64 μM Kinetin. Regenerated shoots were rooted on half-strength MS medium containing 2.85 μM indole-3-butyric acid. This plant regeneration system provides a foundation for genetic transformation of maize.

关键词： maize (Zea mays L.) mature embryo callus induction embryogenic callus plant regeneration

RRAS:A key regulator and an important prognostic biomarker in biliary atresia

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World Journal of Gastroenterology 2011年第6期17卷 796-803页

作者： Rui zhao hao li Chun Shen Shan Zheng Department of Pediatric Surgery Children's Hospital of Fudan University Shanghai 201102 China

AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of BA,and identify the novel prognostic markers for ***:liver tissue samples from control patients,neonatal cholestasis patients,and BA patients at the age of 90 d were pooled for DNA microarray *** analysis was performed using,series test cluster of gene ontology,and Pathway-Finder ***-transcription polymerase chain reaction was performed to confirm changes in selected *** between RRAS gene expression and prognosis of 40 BA patients was analyzed in a 2-year follow-up ***:The 4 identified significant gene expression profiles could confidently separate BA liver tissue from normal and other diseased liver *** included genes were mainly involved in inflammation response and reconstruction of cellular *** significant pathways associated with BA were primarily involved in autoimmune response,activation of T lymphocytes and its related *** RRAS,POMC,SLC26A6 and STX3 genes were important regulatory modules in pathogenesis of *** expression of RRAS was negatively correlated with the elimination rate of jaundice and positively correlated with the occurrence rate of ***:Autoimmune response mediated by T lymphocytes may play a vital role in the pathogenesis of *** RRAS gene is an important regulatory module in the pathogenesis of BA,which may serve as a novel prognostic marker for BA.

关键词： Biliary atresia DNA microarray Bioinformatics RRAS Prognostic biomarker

Preliminary Study on Resistance of the Rice Stem Borer (Chilo Suppressalis) to Fipronil

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Rice science 2005年第4期12卷 295-298页

作者： JIANG Wei-hua HAN zhao-jun hao Ming-li Key Laboratory of Monitoring and Management of Plant Disease and Insects Ministry of Agriculture Nanjing AgriculturalUniversity Nanjing 210095 China E mail. jwh@njau.edu.en

By means of topical application, fipronil resistance was surveyed in the rice stem borer, Chilo suppressalis, from 12 diferent areas in east China from 2001 to 2004. The rice stem borers in most regions of Jiangsu and Anhui were still susceptible to fipronil. But in Wuxi, Jiangsu Province and Cixi, Zhejiang Province, their sensitivity became decreased （resistance ratios were 3.1 and 3.6, respectively）, and the medium level of resistance （resistance ratio was 21.2） was found in Cangnan, Zhejiang Province. So, it was still at the early stage for fipronil resistance development in this pest. Synergism experiments showed that piperonyl butoxide（PBO） had a little effect on both susceptible and resistant borers （synergism ratios were 1.1-1.2）. Though triphenyl phosphate （TPP） and diethyl meleate （DEM） had no effect on the susceptible borers, they had significant synergism on fipronil in the resistant population to fipronil （synergism ratios were 1.8 and 1.6, respectively）, indicating esterase and glutathion S-transferase may be involved in the resistance mechanism. Bioassay with currently used insecticides indicated that triazophos （because of high resistance）, trichlorphon and acephate had very low toxicity to resistant borers. But diazinon, pyridaphenthion, decamethrin and avermeatin showed high toxicity and had no cross resistance to fipronil, which could be considered as substitute insecticides in the resistance managment.

关键词： Chilo suppressalis fipronil resistance relative toxicity

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan li Peng hao Hongmei Duan Fei hao Wen zhao Yudan Gao zhaoyang Yang Kwok-Fai So Xiaoguang li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

Structure, Decarboxylative Behavior and Band Gap Energy of a Nitro-coordinated Potassium Compound

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Structure, Decarboxylative Behavior and Band Gap Energy of a...

Methyl viologen-templated cadmium crystalline material with photo-/thermochromism properties

河南省化学会2016年学术年会

作者： zhao-hao li li-Ping Xue Hai-Xia Wu Jing-Jing Tao Bang-Tun zhao College of Chemistry and Chemical Engineering Luoyang Normal University

A novel nitro-coordinated potassium compound [K(Hntdc)(HO)](Hntdc = 3-nitro-thiophene-2,5-dic arboxylic acid), has been synthesized and characterized. The complex contains KO dimer, which is connected through carboxyl and unusual nitro-coordination of Hntdc anion to form a two-dimensional(2D) layer structure with 5-connected P 2-periodic net(6,3)IIa net. Then the 2D layers are further ext ended by intermolecule hydrogen-bonding to form a three-dimensional(3D) supramoleculalr *** temperature powder X-ray diffractions and thermogravimetric analysis studies exhibit that the framework is thermally stable up to 200 ℃, decarboxylative behavior beyond the temperature is occur ed. Moreover, the optical band gap energy of the complex is also measured and discussed.

关键词： Nitro-coordination Decarboxylative behavior Band gap energy

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Methyl viologen-templated cadmium crystalline material with ...