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基于多阶邻居传播度量和拓扑特征的高影响力节点识别

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中国科学：信息科学 2024年第4期54卷 944-959页

作者：罗余王建波李平杜占玮许小可西南石油大学计算机与软件学院成都610500 香港大学公共卫生学院中国香港999077 北京师范大学计算传播学研究中心珠海519087 北京师范大学新闻传播学院北京100875

如何定量评估复杂网络中节点的影响力是一个重要的研究课题,因为它有助于深入理解网络的结构和功能.现有的多数方法主要基于网络固有拓扑的分析建立,缺少对多阶邻居节点的传播性质和拓扑信息的综合利用,然而它们对影响力节点识别有重要... 详细信息

如何定量评估复杂网络中节点的影响力是一个重要的研究课题,因为它有助于深入理解网络的结构和功能.现有的多数方法主要基于网络固有拓扑的分析建立,缺少对多阶邻居节点的传播性质和拓扑信息的综合利用,然而它们对影响力节点识别有重要影响.为此,本文提出了一种综合多阶邻居传播度量和拓扑特征(multi-order neighbor propagation metrics and topological features,MNPMTF)的算法来有效识别复杂网络中的影响力节点.首先,该算法结合传播模型和最短路径来刻画邻居节点的传播概率,从而量化节点之间信息传播的可能性.其次,考虑多阶邻居中的邻居重叠比形成邻居重叠度,进而量化信息在邻居网络中的传播路径.再次,利用节点的k壳、h指数和聚类系数构成新指标KHC系数,以此来描述节点的拓扑特征.最后,算法综合3阶邻居范围内的传播概率、邻居重叠度和拓扑特征以评估节点的影响力.在9个真实网络上的大量实验表明,所提算法在排序准确性、有效性和区分能力等多方面均优于7种具有代表性的方法,为复杂网络中节点影响力评估提供了一种新的思路.

关键词：传播概率邻居重叠度 KHC系数影响力节点复杂网络

Epidemic Surveillance of Influenza Infections:A Network-Free Strategy—Hong Kong Special Administrative Region,China,2008–2011

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China CDC weekly 2022年第46期4卷 1025-1031,I0002-I0005页

作者： zhanwei du Qi Tan Yuan Bai Lin Wang Benjamin J.Cowling Petter Holme WHO Collaborating Centre for Infectious Disease Epidemiology and Control School of Public HealthLi Ka Shing Faculty of MedicineThe University of Hong KongHong Kong SARChina Laboratory of Data Discovery for Health Limited(D24H) Hong Kong Science and Technology ParkHong Kong SARChina Department of Genetics University of CambridgeCambridgeUK Department of Computer Science Aalto UniversityEspooFinland

Introduction:The ease of coronavirus disease 2019(COVID-19)non-pharmacological interventions and the increased susceptibility during the past COVID-19 pandemic could be a precursor for the resurgence of influenza,potentially leading to a severe outbreak in the winter of 2022 and future *** recent increased availability of data on Electronic Health Records(EHR)in public health systems,offers new opportunities to monitor individuals to mitigate ***:We introduced a new methodology to rank individuals for surveillance in temporal networks,which was more practical than the static *** targeting previously infected nodes,this method used readily available EHR data instead of the contactnetwork ***:We validated this method qualitatively in a real-world cohort study and evaluated our approach quantitatively by comparing it to other surveillance methods on three temporal and empirical *** found that,despite not explicitly exploiting the contacts’network structure,it remained the best or close to the best *** related the performance of the method to the public health goals,the reproduction number of the disease,and the underlying temporal-network structure(e.g.,burstiness).Discussion:The proposed strategy of using historical records for sentinel surveillance selection can be taken as a practical and robust alternative without the knowledge of individual contact behaviors for public health policymakers.

关键词： network policy networks

Heterogeneous influence of individuals’ behavior on mask efficacy in gathering environments

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Frontiers of Engineering Management 2022年第4期9卷 550-562页

作者： Haochen SUN Xiaofan LIU zhanwei du Ye WU Haifeng ZHANG Xiaoke XU College of Information and Communication Engineering Dalian Minzu UniversityDalian 116600China Web Mining Laboratory Department of Media and CommunicationCity University of Hong KongHong KongChina WHO Collaborating Centre for Infectious Disease Epidemiology and Control School of Public HealthLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina Laboratory of Data Discovery for Health Hong Kong Science and Technology ParkHong KongChina Computational Communication Research Center Beijing Normal University(Zhuhai)Zhuhai 519087China School of Journalism and Communication Beijing Normal UniversityBeijing 100875China Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education School of Mathematical ScienceAnhui UniversityHefei 230601China

Wearing masks is an easy way to operate and popular measure for preventing *** masks can slow down the spread of viruses,their efficacy in gathering environments involving heterogeneous person-to-person contacts remains ***,we aim to investigate the epidemic prevention effect of masks in different real-life gathering *** study uses four real interpersonal contact datasets to construct four empirical networks to represent four gathering *** transmission of COVID-19 is simulated using the Monte Carlo simulation *** heterogeneity of individuals can cause mask efficacy in a specific gathering environment to be different from the baseline efficacy in general ***,the heterogeneity of gathering environments causes the epidemic prevention effect of masks to *** masks can greatly reduce the probability of clustered epidemics and the infection scale in primary schools,high schools,and ***,the use of masks alone in primary schools and hospitals cannot control *** high schools with social distancing between classes and in workplaces where the interpersonal contact is relatively sparse,masks can meet the need for *** the heterogeneity of individual behavior,if individuals who are more active in terms of interpersonal contact are prioritized for mask-wearing,the epidemic prevention effect of masks can be ***,asymptomatic infection has varying effects on the prevention effect of masks in different *** effect can be weakened or eliminated by increasing the usage rate of masks in high schools and ***,the effect on primary schools and hospitals cannot be *** study contributes to the accurate evaluation of mask efficacy in various gathering environments to provide scientific guidance for epidemic prevention.

关键词： COVID-19 masks behavioral heterogeneity asymptomatic infection

Semi-Automatic Remote Medicine Monitoring System of Mobile Users

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China Communications 2015年第11期12卷 134-142页

作者： du zhanwei YANG Yongjian College of Computer Science and Technology Jilin University

The advances in biological sensors have resulted in rapid development of various remote medical care systems,which enable extended independent living at home and improvement of quality of life for individuals. Now,it is possible for us to monitor not only people's physical health but also mental health. Considering the incomplete utilization of mental sensors and electronic health record in most Remote medical care systems,we propose a remote medical care system to monitor people's physical and mental health,with the help of ontology model for with Electronic health record knowledge. In this study,the system architecture will be presented first. Then health solutions about the EHR and emotion(the ontology model of EHR and the emotion detection method) are shown. And fi nally,some preliminary tests are given out to show this system's practicability and novelty.

关键词： remote medical care system ontology model,mobile

Nowcasting and Forecasting Seasonal Influenza Epidemics—China,2022-2023

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China CDC weekly 2023年第49期5卷 1100-1106,I0003-I0005页

作者： zhanwei du Zengyang Shao Xiao Zhang Ruohan Chen Tianmu Chen Yuan Bai Lin Wang Eric H.Y.Lau Benjamin J.Cowling WHO Collaborating Center for Infectious Disease Epidemiology and Control School of Public HealthLKS Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Laboratory of Data Discovery for Health Limited Hong Kong Science and Technology ParkHong Kong Special Administrative RegionChina State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics School of Public HealthXiamen UniversityXiamen CityFujian ProvinceChina Department of Genetics University of CambridgeCambridgeUK Institute for Health Transformation&School of Health&Social Development Deakin UniversityMelbourneAustralia

Background:Seasonal influenza resurged in China in February 2023,causing a large number of *** influenza epidemics occurred across China during the coronavirus disease 2019(COVID-19)pandemic,the relaxation of COVID-19 containment measures in December 2022 may have contributed to the spread of acute respiratory infections in winter 2022/***:Using a mathematical model incorporating influenza activity as measured by influenza-like illness(ILI)data for northern and southern regions of China,we reconstructed the seasonal influenza incidence from October 2015 to September 2019 before the COVID-19 *** this trained model,we predicted influenza activities in northern and southern China from March to September ***:We estimated the effective reproduction number Re as 1.08[95%confidence interval(CI):0.51,1.65]in northern China and 1.10(95%CI:0.55,1.67)in southern China at the start of the 2022-2023 influenza *** estimated the infection attack rate of this influenza wave as 18.51%(95%CI:0.00%,37.78%)in northern China and 28.30%(95%CI:14.77%,41.82%)in southern ***:The 2023 spring wave of seasonal influenza in China spread until July 2023 and infected a substantial number of people.

关键词： winter relaxation measures

An Adaptive Anomaly Detection Algorithm Based on CFSFDP

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Computers, Materials & Continua 2021年第8期68卷 2057-2073页

作者： Weiwu Ren Xiaoqiang Di zhanwei du Jianping Zhao School of Computer Science and Technology Changchun University of Science and TechnologyChangchun130022China SRoom 657 J.T.Patterson Labs Bldg.(PAT)Austin78712TXUSA

CFSFDP(Clustering by fast search and find of density peak)is a simple and crisp density clustering *** does not only have the advantages of density clustering algorithm,but also can find the peak of cluster ***,the lack of adaptability makes it difficult to apply in intrusion *** new input cannot be updated in time to the existing profiles,and rebuilding profiles would waste a lot of time and ***,an adaptive anomaly detection algorithm based on CFSFDP is proposed in this *** analyzing the influence of new input on center,edge and discrete points,the adaptive problem mainly focuses on processing with the generation of new cluster by new *** improved algorithm can integrate new input into the existing clustering without changing the original ***,the improved algorithm takes the advantage of multi-core parallel computing to deal with redundant computing.A large number of experiments on intrusion detection on Android platform and KDDCUP 1999 show that the improved algorithm can update the profiles adaptively without affecting the original detection *** with the other classical algorithms,the improved algorithm based on CFSFDP has the good basic performance and more room of improvement.

关键词： Anomaly detection density clustering original profiles adaptive profiles

Edge dislocation-induced strains break the limit of PtNi alloys in boosting Pt mass activity for efficient alkaline hydrogen evolution

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Nano Research 2024年第6期17卷 4711-4719页

作者： Miao Zhou Yao Zhao zhanwei Liu Xueru Zhao Enzuo Liu Liyang Xiao Pengfei Yin Cunku Dong Hui Liu Xiwen du Jing Yang New Energy Materials Institute School of Materials Science and EngineeringTianjin UniversityTianjin 300072China School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China Chemistry Division Brookhaven National LaboratoryUptonNew York 11973USA Advanced Metallic Materials Institute School of Materials Science and EngineeringTianjin UniversityTianjin 300072China

Creating lattice defects and alloying to produce strain effect in Pt-based bimetallic alloys are both effective methods to optimize the crystal and electronic structure and improve the electrocatalytic ***,the principles that govern the alkaline hydrogen evolution reaction(HER)performance remain unclear,which is detrimental to the rational design of efficient Pt-based ***,PtNi alloys with different Pt/Ni ratios and edge dislocations were synthesized,and the effects of Pt/Ni composition and edge dislocations on the alkaline HER electrocatalytic activity of PtNi alloys were systematically *** experimental and theoretical investigations reveal that tuning Pt/Ni ratio results in only 1.1 times enhancements in Pt mass activity,whereas edge dislocations-induced extra tensile strain on Ni site and compressive strain on Pt site further boost the alkaline HER intrinsic activity at all Pt/Ni ***,the introduction of edge dislocations in PtNi alloys could break the limit of alloying in boosting Pt mass activity and result in up to 13.7-fold enhancement,in the case that Pt and Ni contents are nearly identical and thus edge dislocation density reaches the *** mechanism studies demonstrate that the edge dislocation strategy could make a breakthrough in facilitating water dissociation kinetics of PtNi alloys.

关键词： edge dislocations PtNi composition strain effects water dissociation hydrogen evolution reaction

Natural polysaccharide-based smart CXCR4-targeted nano-system for magnified liver fibrosis therapy

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Chinese Chemical Letters 2024年第2期35卷 341-346页

作者： Liqiong Sun Xinping Luo Chenxi Zhou zhanwei Zhou Minjie Sun College of Horticulture Nanjing Agricultural UniversityNanjing 210095China NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients State Key Laboratory of Natural MedicinesDepartment of PharmaceuticsChina Pharmaceutical UniversityNanjing 210009China

Activated hepatic stellate cells(aHSCs),the main source of extracellular matrix deposition,are key targets in liver ***,no effective drug specific to aHSCs has been clinically applied due to poor drug delivery ***,we designed a CXC chemokine receptor 4(CXCR4)-targeted reactive oxygen species(ROS)-responsive platform AMD-Dex-ROS-responsive-sorafenib(ARS)based on natural polysaccharide and thioctic acid frame,which can deliver anti-fibrosis drug represented by sorafenib specifically to aHSCs on account of CXCR4 over-expression on aHSCs,and smartly disassemble via ROS-responsive thioketal rupture relying on high intracellular ROS in HSCs,realized on-demand drug release and effective liver fibrosis ***,in this platform,the CXCR4 antagonist AMD3100 not only enhanced aHSCs targeting efficiency of sorafenib but also effectively magnified the aHSCs elimination of sorafenib by blocking stroma cell derived factor-1(SDF-1)/CXCR4-induced aHSCs protection,resulting in synergistic anti-fibrosis *** platform provided a new approach for drug delivery system design and liver fibrosis treatment.

关键词： Nanoparticle CXCR4 antagonism ROS-responsive Hepatic stellate cells Liver fibrosis

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China CDC weekly 2022年第40期4卷 885-889,I0002-I0005页

作者： Yuan Bai Mingda Xu Caifen Liu Mingwang Shen Lin Wang Linwei Tian Suoyi Tan Lei Zhang Petter Holme Xin Lu Eric H.Y.Lau Benjamin J.Cowling zhanwei du WHO Collaborating Centre for Infectious Disease Epidemiology and Control School of Public HealthLi Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Laboratory of Data Discovery for Health Limited(D24H) Hong Kong Science ParkHong Kong Special Administrative RegionChina China-Australia Joint Research Center for Infectious Diseases School of Public HealthXi’an Jiaotong University Health Science CenterXi’an CityShaanxi ProvinceChina Department of Genetics University of CambridgeCambridge CB23EHUK College of Systems Engineering National University of Defense TechnologyChangsha CityHunan ProvinceChina Department of Computer Science Aalto UniversityEspooFinland Center for Computational Social Science Kobe UniversityKobeJapan

Introduction:Minimizing the importation and exportation risks of coronavirus disease 2019(COVID-19)is a primary concern for sustaining the“Dynamic COVID-zero”strategy in *** estimation is essential for cities to conduct before relaxing border control ***:Informed by the daily number of passengers traveling between 367 prefectures(cities)in China,this study used a stochastic metapopulation model parameterized with COVID-19 epidemic characteristics to estimate the importation and exportation ***:Under the transmission scenario(R0=5.49),this study estimated the cumulative case incidence of Changchun City,Jilin Province as 3,233(95%confidence interval:1,480,4,986)before a lockdown on March 14,2022,which is close to the 3,168 cases reported in real life by March 16,*** a total of 367 prefectures(cities),127(35%)had high exportation risks according to the simulation and could transmit the disease to 50%of all other regions within a period from 17 to 94 *** average time until a new infection arrives in a location in 1 of the 367 prefectures(cities)ranged from 26 to 101 ***:Estimating COVID-19 importation and exportation risks is necessary for preparedness,prevention,and control measures of COVID-19—especially when new variants emerge.

关键词： Export Changchun prevention