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Synergistic creation of highly stable strain-insensitive pressure sensors by in-plane strain modulation and quasi-homogenous interfacial design

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Journal of Materials Science & Technology 2023年第28期159卷 72-80页

作者： Xuyang Feng Shaoxiong Hu Jiajie Yu zhanpeng guo Rui Wang Wei Zhu Yuan Deng School of Materials Science and Engineering Beihang UniversityBeijing 100191China Key Laboratory of Intelligent Sensing Materials and Chip Integration Technology of Zhejiang Province Hangzhou Innovation Institute of Beihang UniversityHangzhou 310052China Research Institute for Frontier Science Beihang UniversityBeijing 100083China

The urgent requirement of electronic skin conformably attached to nonplanar surfaces to provide sta-ble monitoring in areas of healthcare,prosthetics,and robotics promotes the development of strain-insensitive/unperturbed pressure *** main challenges lie in:(1)stretchability and conduc-tive stability of flexible electrodes and(2)mechanical stability of heterogeneous *** study presents a highly stable strain-insensitive pressure sensor achieved by in-plane strain modulation and quasi-homogenous interfacial *** modulation of stretchable electrodes by both periodic mi-crostructured engineering and pre-stretching strategies(called“island-ripple”)was employed to suppress microcracks *** improvement in stretchability and cyclic conductive stability of electrodes was identified by finite element analysis and experimental *** pre-stretched microconed stretchable electrode with a low sheet resistance of 0.546sq^(−1) shows a maximum deformation of up to 80%and excellent cyclic conductive stability over 10000 times under 30%***-homogenous interface strategy by the CNTs/PDMS system was employed to enhance the mechanical and electrical sta-bility of the electrode-active materials interface,demonstrating a strong peel strength and shear strength of>40.9 N/m and>124.8 kPa,*** as-prepared strain-insensitive pressure sensor provides constant sensing performance over 5000 stretching-releasing cycles within 20%*** addition,a 4×4 pixel strain-insensitive pressure sensor array with reduced cross-talk circuit design was further integrated to identify the shape and weight of different objects under *** stretchability and sta-bility of our sensor enable it to be applied in stretchable electronics with great potential.

关键词： Strain-insensitive/unperturbed pressure sensor Stretchable electrode Finite element analysis Quasi-homogenous design

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Enhanced electrical and mechanical properties of Bi_(2)Te_(3)-based thermoelectric thick films enabled by a practical dynamic regulation strategy

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Journal of Materiomics 2024年第2期10卷 480-489页

作者： Jie Zhou Wei Zhu Qingqing Zhang Guangyu Han YuTong Liu zhanpeng guo Siming guo Yue Huang Yuan Deng School of Materials Science and Engineering Beihang UniversityBeijing 100191China Research Institute for Frontier Science Beihang UniversityBeijing 100191China Key Laboratory of Intelligent Sensing Materials and Chip Integration Technology of Zhejiang Province Hangzhou Innovation Institute of Beihang UniversityHangzhou310051China

The application of high-density and high-performance micro thermoelectric devices is still in its infancy,mainly restricted by the low performance of Bi_(2)Te_(3)-based thick film as well as the limited device *** this study,we proposed a dynamic regulation strategy to simultaneously strengthen the thermoelectric and mechanical properties for n-type Bi_(2)Te_(3)-based thick *** effects of growth temperature and time on thermoelectric properties have been firstly *** the thermoelectric properties exhibit consistent degradation with increasing thickness at static growth temperature,an effective rising temperature method is introduced to dynamically regulate the nucleation rate and growing diffusion ***,the grain refinement with compact texture structure leads to a relatively large carrier mobility(77.1 cm^(2)·V^(-1)·s^(-1))and appropriate concentration(5.25×10^(19)cm^(-3))as well as further 12%improvement of power factor with an average value up to 12.0 mW·cm^(-1)·K^(-2)over a wide temperature ranging from 313 K to 453 ***,significant enhancement of mechanical property is also achieved with high elastic modules(56.03 GPa),hardness(0.63 GPa)and large energy dissipation capacity to prevent *** study provides a practical solution with dynamic temperature control to fabricate high-performance Bi_(2)Te_(3) thick films with enhanced mechanical property and pro-cessing feasibility for micro thermoelectric devices.

关键词： Bi_(2)Te_(3)material Thick film Magnetron sputter Dynamic temperature Thermoelectric property Mechanical property

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Can muscle-derived stem cells serve as seed cells to repair spinal cord injury?

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Neural Regeneration Research 2010年第19期5卷 1451-1455页

作者： Xifan Mei Chang Liu Gang Lv Yansong Wang Quanshuang Li zhanpeng guo Shiqiong Liu He Zhang Department of Orthopedics First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China Department of Endocrinology First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China Department of Emergency First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China

Muscle-derived stem cells （MDSCs） can come from a number of different sources, which are easy to isolate and culture, and are also useful in the transformation and expression of exogenous genes. Therefore, MDSCs could possibly be used for gene therapy in the treatment of neurological diseases. However, research on MDSCs has focused on identifying phenotypes and induced differentiation, with few in vivo animal experiments conducted. In this study, MDSCs were selected as seed cells and implanted into the rat spinal cord injury area. Results demonstrated that the MDSCs survived, migrated, and were distributed along the spinal nerves. Moreover, the motor function of rat lower limbs improved significantly, suggesting that MDSCs could be used as seed cells to repair spinal cord injury.

关键词： muscle-derived stem cells green fluorescent protein transplantation spinal cord injury rats

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Green tea polyphenols protect spinal cord neurons against hydrogen peroxide-induced oxidative stress

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Neural Regeneration Research 2014年第14期9卷 1379-1385页

作者： Jianbo Zhao Shiqiang Fang Yajiang Yuan zhanpeng guo Jinhao Zeng Yue guo Peifu Tang Xifan Mei Vertebral Column Ward Department of OrthopedicsFirst Affiliated Hospital of Liaoning Medical University Department of Orthopedics General Hospital of People’s Liberation Army

Green tea polyphenols are strong antioxidants and can reduce free radical damage. To investigate their neuroprotective potential, we induced oxidative damage in spinal cord neurons using hydrogen peroxide, and applied different concentrations （50-200μg,/mL） of green tea polyphenol to the cell medium for 24 hours. Measurements of superoxide dismutase activity, malondialdehyde content, and expression of apoptosis-related genes and proteins revealed that green tea polyphenol effectively alleviated oxidative stress. Our results indicate that green tea polyphenols play a protective role in spinal cord neurons under oxidative stress.

关键词： nerve regeneration spinal cord injury nerve cells green tea polyphenols spinal cordneurons oxidative stress apoptosis malondialdehyde superoxide dismutase rats NSFC grant neural regeneration

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Neuron-like differentiation of adult rat bone marrow stromal cells induced by transforming growth factor-beta and brain-derived neurotrophic factor

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Neural Regeneration Research 2009年第4期4卷 297-301页

作者： Chang Liu Xifan Mei Gang LU Yansong Wang Quanshuang Li zhanpeng guo Department of Endocrinology First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China Department of Orthopaedics First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China Department of Emergency First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China

BACKGROUND： It has been demonstrated that transforming growth factor-β （TGF-β） and brain- derived neurotrophic factor （BDNF） can induce stem cell differentiation into neuron-like cells. OBJECTIVE： To investigate the efficacy of TGF-β and BDNF at inducing the differentiation of adult rat bone marrow stromal cells （BMSCs） into neuron-like cells, both in combination or alone. DESIGN, TIME AND SETTING： A comparative observation experiment was performed at the Department of Orthopedics, First Affiliated Hospital of Liaoning Medical University between October 2007 and January 2008. MATERIALS： TGF-~ and BDNF were purchased from Sigma, USA; mouse anti-rat neuron specific enolase, neurofilament and glial fibrillary acidic protein were purchased from Beijing HMHL Biochem Ltd., China. METHODS： BMSCs were isolated from rats aged 4 weeks and incubated with TGF-β（1μ g/L） and/or BDNF （50 μ g/mL）. MAIN OUTCOME MEASURES： Expression of neuron-specific enolase, neurofilament and glial fibrillary acidic protein were determined by immunocytochemistry. RESULTS： BMSCs differentiated into neuron-like cells following induction of TGF-β and BDNF, and expressed both neuron-specific enolase and neurofilament. The percent of positive cells was significantly greater in the combination group than those induced with TGF-β or BDNF alone （P 〈 0.01）. CONCLUSION： Treatment of BMSCs with a combination of TGF-β and BDNF induced differentiation into neuron-like cells, with the induction being significantly greater than with TGF-β or BDNF alone.

关键词： bone marrow stromal cells green fluorescent protein transforming growth factor-β brain-derived neurotrophic factor neuron-like cells

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Negative effects of Notch1 on the differentiation of muscle-derived stem cells into neuronal-like cells

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Neural Regeneration Research 2011年第31期6卷 2414-2418页

作者： Xifan Mei Chang Liu zhanpeng guo Yajiang Yuan Shiqiang Fang Yansong Wang Yue guo Jinhao Zeng Department of Orthopedics First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China Department of Endocrinology First Affiliated Hospital of Liaoning Medical University Jinzhou 121000 Liaoning Province China

We cultured rat muscle-derived stem cells in medium containing nerve growth factor and basic fi-broblast growth factor to induce neuronal-like cell *** staining and reverse transcription-PCR showed that the differentiated muscle-derived stem cells exhibited processes similar to those of neuronal-like cells and neuron-specific enolase expression,but Notch1 mRNA and protein expression was ***-regulation of Notch1 expression may facilitate neuronal-like cell differentiation from muscle-derived stem cells.

关键词： muscle-derived stem cells neuronal-like cells Notch signal pathway Notch1 differentiation neural regeneration

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Protein hairy enhancer of split-1 expression during differentiation of muscle-derived stem cells into neuron-like cells

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Neural Regeneration Research 2012年第28期7卷 2182-2187页

作者： Mina Huang zhanpeng guo Kun Liu Xifan Mei Shiqiang Fang Jinhao Zeng Yansong Wang Yajiang Yuan Department of Nursing College Liaoning Medical College Jinzhou 121000 Liaoning Province China Department of Orthopedics FirstAffiliated Hospital of Liaoning Medical College Jinzhou 121000 Liaoning Province China

Muscle-derived stem cells were isolated from the skeletal muscle of Sprague-Dawley neonatal rats aged 3 days old. Cells at passage 5 were incubated in Dulbecco＇s modified Eagle＇s medium supplemented with 10% （v/v） fetal bovine serum, 20 IJg/L nerve growth factor, 20 pg/L basic fibroblast growth factor and 1% （v/v） penicillin for 6 days. Cells presented with long processes, similar to nerve cells. Connections were formed between cell processes. Immunocytochemical staining with neuron specific enolase verified that cells differentiated into neuron-like cells. Immunofluorescence cytochemistry and western blot results revealed that the expression of protein hairy enhancer of split-1 was significantly reduced. These results indicate that low expression of protein hairy enhancer of split-1 participates in the differentiation of muscle-derived stem cells into neuron-like cells.

关键词： muscle-derived stem cells neuron-like cells protein hairy enhancer of split-l proliferation neuronspecific enolase neural regeneration

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衣康酸基环氧树脂和双酚A环氧树脂性能对比研究

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电工技术学报 2022年第9期37卷 2366-2376页

作者：刘贺晨郭展鹏李岩周松松吴璇华北电力大学河北省输变电设备安全防御重点实验室保定071003 中国电力科学研究院有限公司北京100192

为探索环保型生物基环氧树脂在电气领域的应用前景,该文比较了一种生物基树脂——衣康酸基环氧树脂(EIA)与双酚A环氧树脂(DGEBA)在理化参数、热性能、力学性能及电气绝缘性能等方面的优缺点。研究结果表明,EIA与DGEBA的环氧当量接近,同... 详细信息

为探索环保型生物基环氧树脂在电气领域的应用前景,该文比较了一种生物基树脂——衣康酸基环氧树脂(EIA)与双酚A环氧树脂(DGEBA)在理化参数、热性能、力学性能及电气绝缘性能等方面的优缺点。研究结果表明,EIA与DGEBA的环氧当量接近,同时两种树脂均具有典型的粘-温特性,EIA的流变性能略优于DGEBA,保证了其可加工性;EIA固化体系的玻璃化转变温度和5%热裂解温度略低于DGEBA;EIA固化体系的击穿场强(32.1kV/mm)略低于DGEBA(36.7kV/mm),且泄漏电流高于DGEBA约13.4%,表明EIA的电气绝缘性能稍弱于DGEBA;力学性能测试表明,EIA固化体系的平均抗拉强度和弯曲强度分别比DGEBA低15.3%和28.5%;与此同时,EIA固化体系的吸水率略高于DGEBA,且高温水解能力较强,或将限制其户外应用前景。综上所述,EIA作为基体树脂受交联密度与分子内酯键影响,较双酚A环氧树脂在力学性能、热稳定性、电气强度方面略有不足,耐热性、黏性相近,而在可降解特性、环保性等方面更优异。后期可通过增加交联度以及通过与双酚A等其他类型环氧树脂进行共混以提高其各项性能。

关键词：环保衣康酸基环氧树脂双酚A环氧树脂性能对比

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衣康酸基环氧树脂与双酚A环氧树脂的电树枝特性对比

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高电压技术 2022年第7期48卷 2607-2615页

作者：刘贺晨郭展鹏刘云鹏周松松吴璇华北电力大学河北省输变电设备安全防御重点实验室保定071003 华北电力大学新能源电力系统国家重点实验室北京102206 中国电力科学研究院有限公司北京100192

衣康酸基环氧树脂(EIA)是利用可再生资源衣康酸制备的环保型环氧树脂,具备应用于电工绝缘材料的前景。为此,探索了EIA的电树枝引发及生长特性,并与常规E–51型环氧树脂(EP)进行了对比研究。通过试验观测了工频电压下两种树脂中电树枝的... 详细信息

衣康酸基环氧树脂(EIA)是利用可再生资源衣康酸制备的环保型环氧树脂,具备应用于电工绝缘材料的前景。为此,探索了EIA的电树枝引发及生长特性,并与常规E–51型环氧树脂(EP)进行了对比研究。通过试验观测了工频电压下两种树脂中电树枝的引发特性以及12 kV和14 kV下的电树枝生长情况,并采用分子动力学模拟(MD)方法建立了EIA和EP的交联结构模型并计算了其微观结构参数以分析其分子结构对其耐电树枝特性的影响机理。试验及MD仿真结果表明,EP树脂存在庞大的苯基链结构,限制了聚合物主链的旋转或移动,自由体积较小,导致其电树枝引发电压较高,但电树枝主要以枝状电树枝为主,后续生长较为迅速;相对而言,EIA树脂分子交联模型为柔性长链结构,自由体积占比较大,其电树枝引发电压较低且引发后短时间内增长较快,但其电树枝主要以丛状电树枝为主,后续生长缓慢。

关键词：衣康酸基环氧树脂双酚A环氧树脂电树枝特性分子模拟微观结构

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直流预压时间对直流叠加冲击电压下XLPE中电树枝引发特性的影响

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高电压技术 2021年第2期47卷 671-678页

作者：刘贺晨徐晓彬刘云鹏蒙绍新郭展鹏张铭嘉华北电力大学河北省输变电设备安全防御重点实验室保定071003 华北电力大学新能源电力系统国家重点实验室北京102206 中国电力科学研究院有限公司电网环境保护国家重点实验室武汉430074

为探究直流预压时间对直流叠加冲击电压下电树枝引发特性的影响,在幅值为0、±10 kV预压时间为1、10、60、180min的直流偏置电压下分别叠加±50k V的雷电冲击电压。此外,利用双极性载流子输运模型对复合电压下针尖附近空间电荷及电场分... 详细信息

为探究直流预压时间对直流叠加冲击电压下电树枝引发特性的影响,在幅值为0、±10 kV预压时间为1、10、60、180min的直流偏置电压下分别叠加±50k V的雷电冲击电压。此外,利用双极性载流子输运模型对复合电压下针尖附近空间电荷及电场分布进行了仿真分析。试验及仿真结果指出,随着直流电压作用时间的增加,复合电压下的电树枝引发长度逐渐增加,介质内部空间电荷浓度及分布范围有所增加,且复合电压下电树枝引发长度与空间电荷浓度、注入深度以及流注发展过程有关。复合电压作用下电树枝引发长度以及直流电压下空间电荷分布特性与所加电压的极性存在紧密联系,正极性冲击电压下电树枝引发长度明显大于负极性;当直流预压时间及幅值相同时,负极性直流预压下空间电荷浓度及分布范围均大于正极性。

关键词：直流叠加冲击电压电树枝引发特性空间电荷仿真极性效应交联聚乙烯

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