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Traceable ring signature schemes based on SM2 digital signature algorithm and its applications in the data sharing scheme

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Frontiers of Computer Science 2024年第2期18卷 251-253页

作者： yongxin zhang Hong LEI Bin WANG Qinghao WANG Ning LU Wenbo SHI Bangdao CHEN Qiuling YUE R&D Department SSC Holding CompanyLtd.Chengmai 571924China School of Cyberspace Security(School of Cryptography) Hainan UniversityHaikou 570228China College of Computer Science and Engineering Northeastern UniversityShenyang 110819China School of Computer Science and Technology Xidian UniversityXi'an 710071China Blockchain Research Group Oxford-Hainan Blockchain Research InstituteChengmai 571924China

1 Introduction Identity privacy concerns hinder data sharing by casting doubt on the safeguarding of personal information,eroding trust,and impeding the willingness of individuals and organizations to exchange their data[1,2].The traceable ring signatures(TRSs)addresses the contradiction between identity privacy and regulation[3],no scheme has been developed thus far that is based on SM2,the Chinese cryptographic public key algorithm standard,without relying on centralized trust.

关键词： SM2 signature scheme

Interferon-induced MXB protein restricts vimentin-dependent viral infection

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2520-2536页

作者： Dongrong Yi Ni An Quanjie Li Qian Liu Huihan Shao Rui Zhou Jing Wang yongxin zhang Ling Ma Fei Guo Xiaoyu Li Zhenlong Liu Shan Cen Institute of Medicinal Biotechnology Chinese Academy of Medical ScienceBeijing 100050China Institute of Pathogen Biology Chinese Academy of Medical ScienceBeijing 100730China Lady Davis Institute for Medical Research Jewish General HospitalMontrealQuebec H3T 1E2Canada

Type I interferon(IFN)inhibits a wide spectrum of viruses through stimulating the expression of antiviral *** an IFN-induced protein,myxovirus resistance B(MXB)protein was reported to inhibit multiple highly pathogenic human *** remains to be determined whether MXB employs a common mechanism to restrict different ***,we find that IFN alters the subcellular localization of hundreds of host proteins,and this IFN effect is partially lost upon MXB *** results of our mechanistic study reveal that MXB recognizes vimentin(VIM)and recruits protein kinase B(AKT)to phosphorylate VIM at amino acid S38,which leads to reorganization of the VIM network and impairment of intracellular trafficking of virus protein complexes,hence causing a restriction of virus *** results highlight a new function of MXB in modulating VIM-mediated trafficking,which may lead towards a novel broad-spectrum antiviral strategy to control a large group of viruses that depend on VIM for successful replication.

关键词： MXB Vimentin Broad antiviral strategy Cytoskeleton network AKT

Bisulfite-mediated base-free decarboxylative carbonylsulfination of alkenes:access to β-keto sultines

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Science China Chemistry 2024年

作者： yongxin zhang Pan Zhou Xinyue Ma Xiaoxiao Yang Xing Fang Yuxi Wang Chao Shu State Key Laboratory of Green Pesticide Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction CCNU-uOttawa Joint Research Centre College of Chemistry Central China Normal University (CCNU) Key Laboratory of Functional Molecular Solids Ministry of Education Anhui Normal University

A straightforward three-component decarboxylative cross-coupling of α-keto acids, alkenes and sodium bisulfite is established for the construction of otherwise challenging-to-access β-keto sultine derivatives. This reaction involves the photoinduced carbonylsulfination of alkenes and utilizes sodium bisulfite as both a sulfur dioxide surrogate and buffer agent for deprotonation of α-keto carboxylic acids. Of note, the practical procedure featured broad substrate scope and group tolerance for diverse biologically important molecules under mild and operationally simple conditions, using an organic photocatalyst. Mechanistic studies indicated that the transformation proceeds an apparent two-pronged radical addition/radical-polar crossover/SO2insertion/ionic cyclization relay process, distinct from traditional alkenes bifunctionalization.

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RP11-789C1.1 inhibits gastric cancer cell proliferation and accelerates apoptosis via the ATR/CHK1 signaling pathway

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中华医学杂志(英文版) 2024年第15期137卷 1835-1843页

作者： Liu Wenwei Feng Wei zhang yongxin Lei Tianxiang Wang Xiaofeng Qiao Tang Chen Zehong Song Wu Digestive Diseases Center The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen Guangdong China Department of Gastrointestinal Surgery The First Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong China Laboratory of General Surgery The First Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong China Department of Gastrointestinal Surgery The Third Affiliated Hospital of Sun Yat-sen University Guangzhou Guangdong China

Background: Long non-coding RNAs (lncRNAs) plays an important role in the progression of gastric cancer (GC). Their involvement ranges from genetic regulation to cancer progression. However, the mechanistic roles of RP11-789C1.1 in GC are not fully ***: We identified the expression of lncRNA RP11-789C1.1 in GC tissues and cell lines by real-time fluorescent quantitative polymerase chain reaction. A series of functional experiments revealed the effect of RP11-789C1.1 on the proliferation of GC *** vivo experiments verified the effect of RP11-789C1.1 on the biological behavior of a GC cell line. RNA pull-down unveiled RP11-789C1.1 interacting proteins. Western blot analysis indicated the downstream pathway changes of RP11-789C1.1, and an oxaliplatin dosing experiment disclosed the influence of RP11-789C1.1 on the drug sensitivity of ***: Our results demonstrated that RP11-789C1.1 inhibited the proliferation of GC cells and promoted the apoptosis of GC cells. Mechanistically, RP11-789C1.1 inhibited checkpoint kinase 1 (CHK1) phosphorylation by binding ataxiatelangiectasia mutated and Rad3 related (ATR), a serine/threonine-specific protein kinase, promoted GC apoptosis, and mediated oxaliplatin ***: In general, we discovered a tumor suppressor molecule RP11-789C1.1 and confirmed its mechanism of action, providing a theoretical basis for targeted GC therapy.

关键词： Long non-coding RNA RP11-789C1.1 Stomach neoplasms ATR CHK1 Oxaliplatin

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磁极组合式永磁丝杠的结构分析与优化

机械强度 2024年第2期46卷 355-363页

作者：宋晓庆张永鑫张佳琛张晓冬郑州商学院信息与机电工程学院巩义451200

为改善永磁丝杠复杂的螺旋形磁极加工制造难度,对螺旋磁极结构进行改进替代。应用有限元法(Finite Element Method,FEM)对推力和转矩静特性进行仿真,证明丝杠磁极为斜环、螺母磁极为螺旋结构和丝杠磁极为螺旋结构、螺母磁极为斜环的两... 详细信息

为改善永磁丝杠复杂的螺旋形磁极加工制造难度,对螺旋磁极结构进行改进替代。应用有限元法(Finite Element Method,FEM)对推力和转矩静特性进行仿真,证明丝杠磁极为斜环、螺母磁极为螺旋结构和丝杠磁极为螺旋结构、螺母磁极为斜环的两种永磁丝杠结构能够实现平稳传动。由于结构中仍部分存在螺旋结构,故进行实用化改进。方案一是将直环离散的若干圆弧形磁极块阶梯式组合排列;方案二是采用半斜环磁极组合结构。结果表明,后者组合磁极块数更少,在保证运动系统平稳传动的同时,具有更大的推力和转矩。同双螺旋永磁丝杠相比,推力误差和转矩误差仅分别为3.981%和0.583%,故而为替代螺旋磁极的一种较为理想的方案。此外,提出了极距比K的概念,得出K=0.3时,单位磁极产生的电磁推力和转矩最大,磁极利用率最高。在此基础上,将半斜环磁极结构采用Halbach阵列优化,峰值推力和转矩可分别提升42.3%和36.3%,且存在最优辅配比λ=0.4。

关键词：永磁丝杠磁极半斜环 Halbach

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东北抗联忠诚于党的坚定信念探析

长春市委党校学报 2024年第4期 4-11页

作者：张永新中共长春市委党校(长春市行政学院)资政研究中心

忠诚于党的坚定信念是东北抗联精神内涵首要的一条,它不仅是东北抗联性质的内在要求,而且是东北抗联矢志不渝的自觉行动,在东北抗联精神价值体系中居于核心地位。学习研究和弘扬东北抗联忠诚于党的坚定信念,具有重要的理论和实践价值。

关键词：东北抗联忠诚于党价值体系

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具有非线性收获的捕食-食饵模型的建立及分析

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石河子大学学报（自然科学版） 2024年第2期42卷 246-251页

作者：张永鑫罗航李晓伟中北大学数学学院山西太原030051

本文建立并分析了具有非线性收获函数的捕食-食饵模型。首先,讨论了平衡点的存在性,分析结果表明系统始终存在1个灭绝平衡点,且存在2个边界平衡点和1个正平衡点共存的现象;其次,对不同类型平衡点的稳定性进行了分析,发现了系统会出现鞍... 详细信息

本文建立并分析了具有非线性收获函数的捕食-食饵模型。首先,讨论了平衡点的存在性,分析结果表明系统始终存在1个灭绝平衡点,且存在2个边界平衡点和1个正平衡点共存的现象;其次,对不同类型平衡点的稳定性进行了分析,发现了系统会出现鞍结点分支、Hopf分支等复杂的动力学行为。数值模拟结果表明,随着收获强度的改变,捕食者的规模会趋于灭绝、常数或者周期性震荡。这就表明在实际中可通过调节收获强度这一措施来实现控制捕食者数目的目的。本文的理论研究结果可进一步丰富有关具有非线性收获的捕食-食饵模型的研究,为合理收获策略的制定提供理论依据。

关键词：捕食-食饵模型鞍结点分支 Hopf分支动力学行为

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电网调控一体化运行系统的应用研究

电力系统装备 2024年第6期 77-78,105页

作者：张永新国网冀北电力有限公司迁西县供电分公司河北唐山064300

随着社会经济的发展和人民生活水平的提高,电力系统的稳定和高效运行变得尤为重要。电网调控一体化运行系统作为现代电力系统的重要技术手段,在提高电网运行效率、增强电网稳定性方面具有显著优势。文章阐述了电网调控一体化运行系统的... 详细信息

随着社会经济的发展和人民生活水平的提高,电力系统的稳定和高效运行变得尤为重要。电网调控一体化运行系统作为现代电力系统的重要技术手段,在提高电网运行效率、增强电网稳定性方面具有显著优势。文章阐述了电网调控一体化运行系统的原理和特征,研究了该系统的实际运用和效果分析,以期为我国电力行业的持续发展提供理论支持和实践参考依据。

关键词：电网调控一体化运行系统关键技术

电力巡检中改进YOLOv5s的缺陷检测算法研究

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计算机工程与应用 2024年第10期60卷 256-265页

作者：王磊郝涌汀潘明然赵慕东张永鑫张茗宇沈阳理工大学机械工程学院沈阳110159 辽沈工业集团有限公司研发中心沈阳110045

针对无人机进行电力巡检时关键零件的检测精度较低的问题,提出了一种基于YOLOv5s的改进型缺陷检测算法。在骨干网络中引入卷积神经网络注意力模块(CBAM),增强网络对特征图中重要信息的提取效率;将YOLOv5s中原有的PANet特征融合框架替换... 详细信息

针对无人机进行电力巡检时关键零件的检测精度较低的问题,提出了一种基于YOLOv5s的改进型缺陷检测算法。在骨干网络中引入卷积神经网络注意力模块(CBAM),增强网络对特征图中重要信息的提取效率;将YOLOv5s中原有的PANet特征融合框架替换为双向特征金字塔网络(BiFPN),引入可学习的权重,映射不同的学习特征,增加对贡献较大特征的映射。在空间金字塔池化模块(spatial pyramid pooling,SPP)的基础上加入上下文卷积模块,提升特征的表达能力。通过构建航拍数据集进行实验验证,结果表明,改进后的算法mAP达到95.6%,准确率达到93.7%,召回率达到93.8%。为进一步验证算法在嵌入式系统的运行效果,通过缩小网络宽度进行轻量化,利用TensorRT推理引擎,优化了网络结构并加速了模型的推理。将模型加速后部署至Jetson Xavier NX平台进行测试,单帧图像平均运行时间为24.6 ms,检测准确率为90.8%,召回率为90.5%,能够在Jetson Xavier NX设备上对目标实现精准识别。改进后的模型提高了检测精度,体现了算法的有效性,满足电力巡检作业的实时检测需求。

关键词：电力巡检目标检测注意力机制特征融合 YOLO