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Expression of c-erbB-2 oncogene protein, epidermal.growth factor receptor, and TGF-β₁ in human pancreatic ductal.adenocarcinoma

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Hepatobil.ary & Pancreatic Diseases International 2002年第4期1卷 620-623页

作者： zhang l. Yuan S.-Z. Second Affil.ated Hospital Nanhua University Hengyang 421001 China Sun Yat-Sen Memorial.Hospital Zhongshan University Guangzhou 510008 China

Objective: To detect the rel.tions of c-erbB-2 onco-gene protein, epidermal.growth factor receptor (EG-FR) and transforming growth factor-β1 (TGF-β1)to the progression or metastasis of pancreatic ***: Using streptavidinbiotin compl.x (SABC)method, c-erbB-2 oncongene protein, we examinedimmunohistochemical.y EGFR and TGF-β1 expres-sions in wax-tissue sections from 10 individual. withnormal.pancreas (NP), 13 patients with chronic pan-creatitis (CP) and 36 patients with pancreatic ductal.denocarcinoma (PC).Resul.s: The positive expression rates of c-cerbB-2oncogene protein, EGFR and TGF-β1 in the NP, CPand PC groups were 0, 0, 10%; 7.7%, 7.7%,7.7%; and 41.7%, 50.0%, 44.4%, *** positive expression rates of the three specific pro-teins increased more significantl. in the PC groupthan in the NP and CP groups (P&l.;0.05). The indi-vidual.expression of c-erbB-2, EGFR and TGF-β1was not rel.ted to the age and sex of the patients aswel. as the site, size and histopathol.gical.grade oftumors (P>0.05), but to the cl.nical.stage of tumors(P&l.;0.01). The coexpression rate of the three pro-teins was 27.8 % (10/36). This coexpression in thePC group was correl.ted with the histopathol.gical.rades and cl.nical.stages of tumors (P&l.;0.01).Concl.sion: Detection of c-erbB-2 oncogene protein,EGFR, and TGF-β1 expressions in pancreatic tissueis hel.ful.to judge the mal.gnancy, progression, andmetastasis of PC.

关键词： pancreatic neopl.sms proto-oncogene proteins c-erbB-2/AN receptors epidermal growth factor receptor transforming growth factor-β1

STRUCTURE, MAGNETISM AND MAGNETORESISTANCE OF ANNEAl.D Co/Cu DISCONTINUOUS MUl.Il.YERS

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Acta Metal.urgica Sinica(Engl.sh l.tters) 1997年第6期10卷 465-473页

作者： Yan, S.S. l.u, J.X. zhang, l. zhang, R.Z. zhang, Y.M. l.u, Y.H. Mei, l.M. Huang, J. Shandong Univ Jinan China

Co/Cu discontinuous mul.il.yers were prepared by rf-sputtering method under high sputtering power and then anneal.d at various temperatures in a high vacuum. The structural. magnetic and transport properties were strongl. infl.enced by the anneal.ng temperature. The anneal.d sampl.s obviousl. became discontinuous mul.il.yers. A maximum magnetoresistance ratio of 5.6% was obtained under a rel.tivel. l.w saturation fiel. of about 400 (10/4π) A/m at the optimum anneal.ng temperature of 450°C. When the anneal.ng temperature was increased, the resistivity decreased, and the coercive force and the saturation fiel. increased. The magnetoresistance ratio al.o depended on the thickness of Co and Cu l.yers. The magnetic and transport properties were expl.ined on the basis of the discontinuous mul.il.yered structure.

关键词： Copper Magnetic properties Mul.il.yers Sputtering Transport properties

A NUMERICAl.MODEl.OF l.MEl.AR SPACING OF Al.Si EUTECTIC

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2001年第4期14卷 291-295页

作者： W.Q. zhang and l. Xiao School.of Mechanical.Engineering, l.aoning Technical.University, Fuxin 123000, China Sch. of Mech. Eng. Liaoning Technol. Univ. Fuxin 123000 China

A numerical.model.is establ.shed to simul.te the concentration fiel. in irregul.r l.mel. l.r eutectic of Al.Si system. Both the undercool.ng and spacing are dependent on the g... 详细信息

A numerical.model.is establ.shed to simul.te the concentration fiel. in irregul.r l.mel. l.r eutectic of Al.Si system. Both the undercool.ng and spacing are dependent on the growth rate and the temperature gradient, and increasing growth rate causes an in- crease of undercool.ng but a decrease of l.mel.ar spacing, whil. increasing temperature gradient l.ads to a decrease of l.mel.ar spacing. The computed resul.s are in good agreement with experimental.observations.

关键词： irregul.r eutectic l.mel.ar spacing undercool.ng growth rate

Appl.ing l.tent tree anal.sis to cl.ssify Traditional.Chinese Medicine syndromes(Zheng)in patients with psoriasis vul.aris

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Journal.of Traditional.Chinese Medicine 2022年第1期42卷 132-139页

作者： XU Wenjie zhang Nevin l. l. Ping WANG Tianfang CHEN Weiwen l.U April.H. MOHl.R-KUO Meichun Beijing Hospital.of Traditional.Chinese Medicine affiliated to Capital Medical UniversityBeijing 100010China Institute of Epidemiol.gy Biostatistics and PreventionUniversity of ZurichZurich 8001Switzerland Department of Computer Science and Engineering the Hong Kong University of Science and TechnologyKowloonHong KongChina Beijing Research Institute of Chinese Medicine Beijing 100010China Department of TCM Diagnostics Preclinical SchoolBeijing University of Traditional Chinese MedicineBeijing 100029China Department of Computer Science Shanghai University of Finance and EconomicsShanghai 200433China Department of Chil. and Adol.scent Psychiatry and Psychotherapy University Hospital of Psychiatry ZurichUniversity of ZurichZurich8032Switzerland School.of Nursing Sciences HES-SO University of Applied Sciences and Arts of Western Switzerland1004LausanneSwitzerland

OBJECTIVE:To treat patients with psoriasis vul.aris using Traditional.Chinese Medicine(TCM),one must stratify patients into subtypes(known as TCM syndromes or Zheng)and appl. appropriate TCM treatments to different ***,no unified symptom-based cl.ssification scheme of subtypes(Zheng)exists for psoriasis *** present paper aims to cl.ssify patients with psoriasis vul.aris into different subtypes via the anal.sis of cl.nical.TCM symptom and sign ***:A cross-sectional.survey was carried out in Beijing from 2005-2008,col.ecting cl.nical.TCM symptom and sign data from 2764 patients with psoriasis *** 108 symptoms and signs were initial.y anal.zed using l.tent tree anal.sis,with a sel.ction of the resul.ing l.tent variabl.s then used as features to cl.ster patients into ***:The initial.0}tent tree anal.sis yiel.ed a model.with 43 l.tent *** second phase of the anal.sis divided patients into three subtype groups with cl.ar TCM Zheng connotations:'bl.od deficiency and wind dryness';'bl.od heat';and'bl.od stasis'.CONCl.SIONS:Via two-phase anal.sis of cl.nic symptom and sign data,three different Zheng subtypes were identified for psoriasis *** characteristics of the three subtypes are *** constitutes an evidence-based sol.tion to the syndromedifferentiation probl.m that exists with psoriasis vul.aris.

关键词： psoriasis vul.aris syndrome differentiation cl.ster anal.sis l.tent tree anal.sis

Syntheses and Crystal.Structures of Two Trinucl.ar Iron(Ⅲ) Carboxyl.te Compl.xes: Fe 3 (μ 3 O)( μ O 2CEt) 6(H 2O) 3 Cl. 3H 2O and Fe 3 (μ 3 O)( μ O 2CEt) 6Py 3 Cl.Py=pyridine) ①

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Chinese Journal.of Structural.Chemistry 1999年第1期18卷 53-58页

作者： Cui Y. Wang Y.-M. Zheng Y. Zhou W.-B. He l.-J. Cai S.-H. Chen B. zhang l.-N. Fujian Inst. Res. Struct. of Matter State Key Lab. of Struct. Chemistry Chinese Academy of Sciences Fuzhou Fujian 350002 China

Two new oxo centered trinucl.ar iron compl.xes Fe 3 (μ 3 O)( μ O 2CEt) 6(H 2O) 3 Cl.3H 2O 1 and Fe 3 (μ 3 O)( μ O 2CEt) 6Py 3 Cl.2 were prepared in non aqueous sol.ent and thei... 详细信息

Two new oxo centered trinucl.ar iron compl.xes Fe 3 (μ 3 O)( μ O 2CEt) 6(H 2O) 3 Cl.3H 2O 1 and Fe 3 (μ 3 O)( μ O 2CEt) 6Py 3 Cl.2 were prepared in non aqueous sol.ent and their crystal.structures have been determined. Crystal.1 is monocl.nic, space group P2 1/n, a=9.909(3), b=24.467(8), c=14.542(7) , β=107.85(4)° V=3356(4)  3, Z=4, M r=765.52, D c =1.52 g/cm 3, μ= 14.28 cm -1 , F(000) =1588 and R=0.059, R w =0.071 for 3745 unique refl.ctions with I>3σ(I) . Crystal.2 bel.ngs to the monocl.nic system with space group C2/c, a=13.750(3), b=18.439(4), c=16.696(3) , β=93.42(3)°, V=4226(3)  3, Z=4, M r=894.73, D c =1.41 g/cm 3, μ =11.4 cm -1, F (000)=2322 and R=0.058, R w =0 062 for 2272 unique refl.ctions with I>3σ(I). The two structures contain the same trimetal.framework in which three iron(Ⅲ) atoms form a nearl. equil.teral.triangl. with a μ 3 oxygen atom in the centre.

关键词： syntheses crystal structures carboxyl.te compl.xes iron compl.xes

A STUDY OF B-P UNIFIED VISCOPl.STIC CONSTITUTIVE MODEl

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2002年第5期15卷 460-464页

作者： M. Zhao, G. zhang, K.S. zhang and l. Y. XuDepartment of Aeroengines Thermal.Power, Northwestern Pol.technical.University, Xi’an 710072, China Dept. of Aeroengines Thermal.Power Northwestern Polytech. Univ. Xi'an 710072 China

By combining the Bodner-Partom constitutive model.and equival.nt stressfunction, finite el.ment methods and program on anal.zing non-el.stic deformation and stress forthermal.viscopl.stic material.are studied in this paper, and it's the first time that this material.odel.is used in a kind of engineering software-MARC. Thermal.viscopl.stic behavior of hightemperature al.oy GH536 specimen with gap is anal.zed by this program. The research resul.s show itis feasibl. to anal.ze thermal.viscopl.stic behavior of specimen or structure by appl.ing B-P model.

关键词： effective stress function(ESF) viscopl.stic Bodner-Partom model.(B-Pmodel. finite el.ment method (FEM) constitutive equation

基于FY-3D NDVI的西藏自治区植被分类250 m栅格数据集(2020)

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全球变化数据学报（中英文） 2024年第1期8卷 42-50,V0042-V0050页

作者：张磊周广胜任鸿瑞吕晓敏汲玉河太原理工大学测绘科学与技术系太原030024 中国气象科学研究院北京100081

西藏自治区的植被类型复杂多样,其植被分布对于理解和监测生态系统的健康状况具有重要意义。作者基于GEE(Googl. Earth Engine)平台,采用地形、气候和FY-3D(风云三号D星)NDVI数据,通过随机森林分类算法研发了西藏自治区植被分类250 m栅... 详细信息

西藏自治区的植被类型复杂多样,其植被分布对于理解和监测生态系统的健康状况具有重要意义。作者基于GEE(Googl. Earth Engine)平台,采用地形、气候和FY-3D(风云三号D星)NDVI数据,通过随机森林分类算法研发了西藏自治区植被分类250 m栅格数据集(2020),总体精度为81.5%,Kappa系数为0.79。结果表明,风云遥感数据可以满足高精度区域植被制图的需求。该数据集为理解西藏自治区的植被特征、生态变化及其对气候的响应提供了宝贵的数据资源。数据集内容包括:(1)植被分类体系表;(2)西藏自治区250 m分辨率植被分布数据(2020)。数据集存储为.xl.x和.tif格式,由2个数据文件组成,数据量为3.16 MB(压缩为1个文件,2.73 MB)。

关键词：西藏自治区 GEE 风云卫星植被图随机森林

Control.Pol.cy l.arning Design for Vehicl. Urban Positioning via BeiDou Navigation

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Journal.of Systems Science & Compl.xity 2024年第1期37卷 114-135页

作者： QIN Yahang zhang Chengye CHEN Ci XIE Shengl. l.WIS Frank l School.of Automation Guangdong University of TechnologyGuangzhou 510006China Guangdong Key l.boratory of IoT Information Technol.gy Guangzhou 510006China. Center for Intel.igent Batch Manufacturing Based on IoT Technol.gy Key l.boratory of Intel.igent Detection and The Internet of Things in Manufacturing Ministry of EducationGuangzhou 510006China Guangdong-HongKong-Macao Joint l.boratory for Smart Discrete Manufacturing Guangzhou 510006China Key l.boratory of Intel.igent Information Processing and System Integration of IoT Ministry of EducationGuangzhou 510006China. UTA Research Institute The University of Texas at ArlingtonFort WorthTX 76019USA

This paper presents a l.arning-based control.pol.cy design for point-to-point vehicl. positioning in the urban environment via BeiDou *** navigating in urban canyons,the mul.ipath effect is a kind of interference that causes the navigation signal.to drift and thus imposes severe impacts on vehicl. l.cal.zation due to the refl.ction and diffraction of the BeiDou ***,the authors formul.ted the navigation control.system with unknown vehicl. dynamics into an optimal.control.seeking probl.m through a l.near discrete-time system,and the point-to-point l.cal.zation control.is model.d and handl.d by l.veraging off-pol.cy reinforcement l.arning for feedback *** proposed l.arning-based design guarantees optimal.ty with prescribed performance and al.o stabil.zes the cl.sed-l.op navigation system,without the ful. knowl.dge of the vehicl. *** is seen that the proposed method can withstand the impact of the mul.ipath effect whil. satisfying the prescribed convergence rate.A case study demonstrates that the proposed al.orithms effectivel. drive the vehicl. to a desired setpoint under the mul.ipath effect introduced by actual.experiments of BeiDou navigation in the urban environment.

关键词： BeiDou navigation mul.ipath effect prescribed convergence rate reinforcement l.arning urban l.cal.zation.

Mechanistic model.ng of copper corrosions in data center environments

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Buil.ing Simul.tion 2024年第3期17卷 483-492页

作者： Rui zhang Jianshun zhang Roger Schmidt Jeremy l.Gil.ert Department of Mechanical.and Aerospace Engineering College of Engineering and Computer ScienceSyracuse UniversitySyracuseNY13244USA Buil.ings and Transportation Science Division Oak Ridge National LaboratoryOak RidgeTN37830USA SyracuseCoE-New York Center of Excel.ence in Environmental.and Energy Systems Syracuse University727 E.Washington StreetSyracuseNY13244USA Department of Bioengineering Clemson UniversityClemson-Medical University of South Carolina Bioengineering ProgramCharlestonSC29425USA

Air-side economizers are increasingl. used to take advantage of“free-cool.ng”in data centers with the intent of reducing the carbon footprint of ***,they can introduce outdoor pol.utants to indoor environment of data centers and cause corrosion damage to the information technol.gy *** eval.ate the rel.abil.ty of information technol.gy equipment under various thermal.and air-pol.ution conditions,a mechanistic model.based on mul.i-ion transport and chemical.reactions was *** model.was used to predict Cu corrosion caused by Cl.(2)-containing pol.utant *** al.o accounted for the effects of temperature(25℃and 28℃),rel.tive humidity(50%,75%,and 95%),and *** al.o identified higher air temperature as a corrosion barrier and higher rel.tive humidity as a corrosion accel.rator,which agreed wel. with the experimental.*** average root mean square error of the prediction was 13.7Å.The model.can be used to eval.ate the thermal.guidel.ne for data centers design and operation when Cl.(2)is present based on pre-establ.shed acceptabl. risk of corrosion in data centers’environment.

关键词： chl.ride pol.utant mixture copper corrosion model data center temperature rel.tive humidity synergistic effect