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Exact Solutions and Coherence Structures of Generalized Breor-Kaup Equations

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Communications in Theoretical Physics 2008年第12期50卷 1283-1286页

作者： ZHENG Qiang zhang xiao-ping REN Zhong-Zhou Department of Physics Nanjing University Nanjing 210093 China

Using the mapping method based on q-deformed hyperbolic functions,the exact solutions of generalizedBreor-Kaup equations are *** on the solutions,two coherent structures,periodic-branch kink and non-propagating kink,h... 详细信息

关键词： mapping method periodic-branch kink non-propagating kink soliton interaction background

Ground State Properties of Superheavy Nuclei in Macroscopic-Microscopic Model

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Communications in Theoretical Physics 2008年第9期50卷 707-714页

作者： ZHI Qi-Jun REN Zhong-Zhou zhang xiao-ping ZHENG Qiang School of Science Guizhou Normal University Guiyang 550001 China Department of Physics Nanjing University Nanjing 210008 China Center of Theoretical Nuclear Physics National Laboratory of Heavy-Ion Accelerator Lanzhou 730000 China Joint Center for Particle Nuclear Physics and Cosmology Nanjing University Nanjing 210008 China

The ground state properties of superheavy nuclei are systematically calculated by the macroscopic-microscopic (MM) model with the Nilsson *** calculations well produced the ground state binding energies,α-decay energies,and half lives of superheavy *** calculated results are systematically compared with availableexperimental *** calculated results are also compared with theoretical results from other MM models and fromrelativistic mean-field *** calculations and comparisons show that the MM model is reliable in superheavy regionand that the MM model results are not very sensitive to the choice of microscopic single-particle potential.

关键词： macroscopic-microscopic model.superheavy nuclei binding energy half life

Hepatic non-parenchymal cells and extracellular matrix participate in oval cell-mediated liver regeneration

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World Journal of Gastroenterology 2009年第5期15卷 552-560页

作者： Wei zhang xiao-ping Chen Wan-Guang zhang Feng zhang Shuai Xiang Han-Hua Dong Lei zhang Hepatic Surgery Center Tongji Hospital Tongji Medical College HuazhongUniversity of Science and Technology Wuhan 430030 HubeiProvince China

AIM： To elucidate the interaction between non- parenchymal cells, extracellular matrix and oval cells during the restituting process of liver injury induced by partial hepatectomy （PH）. METHODS： We examined the localization of oval cells, non-parenchymal cells, and the extracellular matrix components using immunohistochemical and double immunofluorescent analysis during the proliferation and differentiation of oval cells in N-2- acetylaminofluorene （2-AAF）/PH rat model. RESULTS： By day 2 after PH, small oval cells began to proliferate around the portal area. Most of stellate cells and laminin were present along the hepatic sinusoids in the periportal area. Kupffer cells and fibronectin markedly increased in the whole hepatic Iobule. From day 4 to 9, oval cells spread further into hepatic parenchyma, closely associated with stellate cells, fibronectin and laminin. Kupffer cells admixed with oval cells by day 6 and then decreased in the periportal zone. From day 12 to 15, most of hepatic stellate cells （HSCs）, laminin and fibronectin located around the small hepatocyte nodus, and minority of them appeared in the nodus. Kupffer cells were mainly limited in the pericentral sinusoids. After day 18, the normal liver Iobule structures began to ***： Local hepatic microenvironment may participate in the oval cell-mediated liver regeneration through the cell-cell and cell-matrix interactions.

关键词： Oval cells Liver regeneration Extracellularmatrix Hepatic stellate cells Kupffer cells

Using ^(137)Cs Tracer Technique to Evaluate Erosion and Deposition of Black Soil in Northeast China

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Pedosphere 2006年第2期16卷 201-209页

作者： FANG Hua-Jun YANG Xue-Ming zhang xiao-ping LIANG Ai-Zhen Northeast Institute of Geography and Agricultural Ecology CAS Changchun 130012 （China）. Graduate School of the Chinese Academy of Sciences Beijing 100039 （China） Greenhouse ＆ Processing Crops Research Centre Agriculture ＆ Agri-Food Canada Harrow Ontario NOR 1 GO （Canada）

Soil and water losses through erosion have been serious in the black soil region of Northeast China. Therefore, a sloping cultivated land in Songnen Plain was selected as a case study to： 1） determine the ^137Cs reference inventory in the study area; 2） calculate erosion and deposition rates of black soil on different slope locations; 3） conduct a sensitivity analysis of some model parameters; and 4） compare overall outputs using four different models. Three transects were set in the field with five slope locations for each transect, including summit, shoulder-slope, back-slope, foot-slope, and toe-slope. Field measurements and model simulation were used to estimate a bomb-derived ^137Cs reference inventory in the study area. Soil erosion and deposition rates were estimated using four ^137Cs models and percentage of ^137Cs loss/gain. The ^137Cs reference value in the study area was 2 232.8 Bq m^-2 with ^137Cs showing a clear topographic pattern, decreasing from the summit to shoulder-slope, then increasing again at the foot-slope and reaching a maximum at the toe-slope, Predicted soil redistribution rates for different slope locations varied. Among models, the Yang Model （YANG-M） overestimated erosion loss but underestimated deposition. However, the standard mass balance model （MBM1） gave predictions similar to a mass balance model incorporating soil movement by tillage （MBM2）. Sensitivity analysis of the proportion factor and distribution pattern of ^137Cs in the surface layer demonstrated the impact of ^137Cs enrichment on calculation of the soil erosion rate. Factors influencing the redistribution of fallout ^137Cs in landscape should be fully considered as calculating soil redistribution rate using ^137Cs technique.

关键词： black soil cesium-137 (^137Cs) Northeast China quantitative models soil erosion

Purification and Characterization of Protein Tyrosine Phosphatase MEG1 and Preparation of Anti-PTPMEG1 Antibody

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Chemical Research in Chinese Universities 2010年第4期26卷 591-595页

作者： zhang xiao-ping XING Shu xiao-xia LIN Fan FU Xue-qi LI Wan-nan Edmond H. Fischer Signal Transduction Laboratory College of Life Sciences Jilin University Changchun 130012 P. R. China Clinical Laboratory China Japan Union Hospital Jilin University Changchun 130033 P. R. China Key Laboratory for Molecular Enzymology and Engineering Ministry of Education Jilin University Changchun 130012 P. R. China School of Life Science Northeast Normal University Changchun 130024 P. R. China

PTPMEGI is an intracellular protein tyrosine phosphatase（PTP）, which contains FERM and PDZ domains This study focuses our attention on the expression, purification and characterization of catalytic domain of PTPMEG1 （AMEG1） and preparation of its polyclonal antibody. A cDNA fragment encoding AMEG1 protein（amino acid residues 643-926） was amplified by PCR and then cloned into the pT7-7 vector. Both soluble and insoluble recombinant AMEG1 proteins were observed after induction by IPTG. Soluble AMEG1 was purified via two chromatographic steps, and the purified enzyme was characterized. With para-nitrophenylphosphate（pNPP） as a substrate, AMEG1 exhibited typical enzymatic characteristics of classic PTPs and classical Michaelis-Menten kinetics. Insoluble AMEG1, which was mainly distributed in the inclusion body of E. coli cells extracts, was purified by preparative electrophoresis gel for the preparation of the polyclonal antibody. A rabbit was immunized with AMEG1 purified by preparative electrophoresis to generate anti-AMEG1 antibody. Anti-serum was collected on 28th day after initial injection and purified via affinity chromatography. The purified polyconal antibody displayed a satisfactory titer and sensitivity.

关键词： Protein tyrosine phosphatase(PTP) PTPMEG1 AMEG 1 Polyclonal antibody

Advanced primary peritoneal carcinoma:clinicopathological and prognostic factor analyses

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第6期9卷 435-440页

作者： Chao zhang xiao-ping LI Heng CUI Dan-hua SHEN Li-hui WEI Gynecological Oncology Center Peking University People＇s Hospital Beijing 100044 China

Objective: To investigate the factors favoring a positive prognosis for advanced primary peritoneal carcinoma (PPC). Methods: Twenty-four cases meeting the criteria for PPC were analyzed retrospectively for the clinicopathologic profiles. Im- munohistochemistry was used to determine the expressions of p53, Top2α, Ki-67 and Her-2/neu. Then all these clinicopa- thological factors and molecular markers were correlated with the prognosis. Results: There were 15 cases of primary peritoneal serous papillary carcinoma (PPSPC), 6 cases of mixed epithelial carcinoma (MEC) and 3 cases of malignant mixed Mullerian tumor (MMMT). All patients underwent cytoreductive surgery with optimal debulking achieved in 3 cases. Among those re- ceiving first-line chemotherapy, 13 patients received the TP regimen (paclitaxel-cisplatin or carboplatin) and 7 patients received the PAC regimen (cisplatin-doxorubicin-cyclophosphamide). The median overall survival of all patients was 42 months, while the breakdown for survival time for patients with PPSPC, MMT and MEC was 44, 13 and 19 months, respectively. The expressions of p53, Top2α and Ki-67 were all demonstrated in 11 cases respectively. None showed the expression of Her-2/neu. There were significant differences in the median survival between patients with PPSPC and those with MMMT (44 months vs 13 months, P<0.05), also between patients receiving TP combination and those receiving the PAC regimen (75 months vs 28 months, P<0.05). Another significant difference in the median progression-free survival (PFS) was identified between patients with positive p53 immunostaining and those with negative p53 immunostaining (15 months vs 47 months, P<0.05), whereas age, menopausal status, residual tumor size and the other molecular factors did not significantly impact survival. Conclusion: Patients with PPC should be treated with a comprehensive management plan including appropriate cytoreductive surgery and responsive chemotherapy. Overestimating an opt

关键词： Primary peritoneal carcinoma (PPC) Cytoreductive surgery Chemotherapy Immunohistochemistry Prognosis

Frequency Stabilization Using Polarization Spectroscopy and Cr-He Hollow Cathode Discharge

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Chinese Physics Letters 2011年第9期28卷 136-138页

作者： YIN Cong QIAN Jin zhang xiao-ping SHI Chun-Ying WANG Han-ping HUANG Sheng-Ye Division of Metrology in Length and Precision Engineering National Institute of MetrologyBeijing 100013 China South Industry Academe Beijing 100089

Polarization spectroscopy is used to lock a frequency-doubled Ti:Sapphire laser to the 425.5 nm ^(7)S3→^(7)P_(4)0 transition of ^(52)Cr.A Cr−He hollow cathode discharge cell is designed and fabricated to produce Cr atom vapor instead of a high temperature *** any modulation devices or lock-in amplifiers,a high signal-to-background level polarization spectroscopy signal is ***,a frequency fluctuation of±295 kHz for more than one hour is achieved.

关键词： polarization signal Polarization

Pyrosequencing of nirS gene revealed spatial variation of denitrifying bacterial assemblages in response to wetland desertification at Tibet plateau

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Journal of Mountain Science 2019年第5期16卷 1121-1134页

作者： GU Yun-fu LIU Ting BAI Yan XIANG Quan-ju zhang xiao-ping CHEN Qiang Department of Microbiology College of Resource Science and Technology Sichuan Agricultural University

Amplicon sequencing of functional genes is a powerful technique to explore the diversity and abundance of microbes involved in biogeochemical processes. One such key process, denitrification, is of particular importance because it can transform nitrate(NO3-) to N2 gas that is released to the atmosphere. In nitrogen limited alpine wetlands, assessing bacterial denitrification under the stress of wetland desertification is fundamental to understand nutrients, especially nitrogen cycling in alpine wetlands, and thus imperative for the maintenance of healthy alpine wetland ecosystems. We applied amplicon sequencing of the nirS gene to analyze the response of denitrifying bacterial community to alpine wetland desertification in Zoige, China. Raw reads were processed for quality, translated with frameshift correction, and a total of 95,316 nirS gene sequences were used for rarefaction analysis, and 1011 OTUs were detected and used in downstream analysis. Compared to the pristine swamp soil, edaphic parameters including water content, organic carbon, total nitrogen, total phosphorous, available nitrogen, available phosphorous and potential denitrification rate were significantly decreased in the moderately degraded meadow soil and in severely degraded sandy soil. Diversity of the soil nirS-type denitrifying bacteria communities increased along the Zoige wetland desertification, and Proteobacteria and Chloroflexi were the dominant denitrifying bacterial species. Genus Cupriavidus(formerly Wautersia), Azoarcus, Azospira, Thiothrix, and Rhizobiales were significantly(P<0.05) depleted along the wetland desertification succession. Soil available phosphorous was the key determinant of the composition of the nirS gene containing denitrifying bacterial communities. The proportion of depleted taxa increased along the desertification of the Zoige wetland, suggesting that wetland desertification created specific physicochemical conditions that decreased the microhabitats for bacteria

关键词： Wetland desertification Amplicon sequencing nirS bacteria Differential abundance analysis

A facile synthesis of the spiroindoline-based growth hormone secretagogue,MK-677

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Chinese Chemical Letters 2012年第6期23卷 661-664页

作者： Xian Liang Qi Er Qun Yang Jun Tao zhang Tao Wang xiao ping Cao State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000 China

A facile and improved route for the synthesis of the orally active spiroindoline-based growth hormone secretagogue, MK-677 was described. The key step adopted the Fischer indole/reduction strategy. The preparation of the key intermediates N-protected piperidine carboxaldehyde 5 and the N-Boc-O-benzyl-D-serine （2） are also optimized.

关键词： MK-677 Synthesis Improved route Fischer indole/reduction